scholarly journals Glucose Sensor Based on Ellipsometry and Circular Dichroism in Achiral Plasmonic Structure

Author(s):  
Younes Mazhdi ◽  
S.M. Hamidi ◽  
Vladimir Belotelov ◽  
Alexander Chernov

Various efforts have been made to detect minimum value of glucose in any medium like water or body buffer solutions with high-sensitivity, accurate, and low-cost sensors in order to enhance life style. Therefore, the present study was done to investigate reliability of two-dimensional plasmonic structure by circular dichroism (CD) and ellipsometry tools in different concentrations of glucose. Our results confirmed a dependency of the CD signal on glucose concentrations and also a very good sensitivity based on the phase difference between each polarization in ellipsometry parameters with the help of an achiral plasmonic structure.

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Y. Mazhdi ◽  
S. M. Hamidi

AbstractVarious efforts have been made to detect minimum amounts of any toxic materials in water or the neurotoxic effect of venom (Odontobuthus Doriae Scorpion) in the human’s blood serum nerve by high-sensitivity, accurate, and low-cost sensors in order to enhance life style. Therefore, the present study was done to investigate reliability of two-dimensional plasmonic structure and circular dichroism (CD) in toxic samples in order to measure and determine venom concentrations and its neurotoxic effect on humans҆ blood serum Neurotransmitter analytes. Our results confirmed dependency of CD signal to neurotoxic effect of venom concentrations and good sensitivity of this sensor with the help of achiral plasmonic structure.


2021 ◽  
Author(s):  
Hisako Sato ◽  
Sumio Aisawa ◽  
Honoka Ida ◽  
Masaru Shimizu ◽  
Keisuke Watanabe ◽  
...  

2020 ◽  
Vol 10 (23) ◽  
pp. 8419
Author(s):  
Adriana Remes ◽  
Florica Manea ◽  
Sorina Motoc (m. Ilies) ◽  
Anamaria Baciu ◽  
Elisabeta I. Szerb ◽  
...  

A novel electrochemical glucose sensor was developed, based on a multiwall carbon nanotubes (MWCNTs)-copper-1,3,5-benzenetricarboxylic acid (CuBTC)-epoxy composite electrode, named MWCNT-CuBTC. The electrode nanocomposite was prepared by a two-roll mill procedure and characterized morphostructurally by scanning electron microscopy (SEM). The CuBTC formed defined crystals with a wide size distribution, which were well dispersed and embedded in the MWCNTs. Its electrical conductivity was determined by four-point probe contact (DC) conductivity measurements. The electroactive surface area, determined using cyclic voltammetry (CV), was found to be 6.9 times higher than the geometrical one. The results of the electrochemical measurements using CV, linear sweep voltammetry (LSV), differential pulse voltammetry (DPV), chronoamperometry (CA) and multiple pulse amperometry (MPA) showed that the MWCNT-CuBTC composite electrode displayed high electrocatalytic activity toward the oxidation of glucose and, as a consequence, very high sensitivity. The best sensitivity of 14,949 µAmM−1cm−1 was reached using MPA at the potential value of 0.6 V/SCE, which was much higher in comparison with other copper-based electrodes reported in the literature. The good analytical performance, low cost and simple preparation method make this novel electrode material promising for the development of an effective glucose sensor.


Marine Drugs ◽  
2019 ◽  
Vol 17 (5) ◽  
pp. 289 ◽  
Author(s):  
Xiuli Xu ◽  
Jiahui Han ◽  
Yanan Wang ◽  
Rui Lin ◽  
Haijin Yang ◽  
...  

Two new spiro-heterocyclic γ-lactam derivatives, cephalimysins M (1) and N (2), were isolated from the fermentation cultures of the marine-derived fungus Aspergillus fumigatus CUGBMF17018. Two known analogues, pseurotin A (3) and FD-838 (4), as well as four previously reported helvolic acid derivatives, 16-O-propionyl-16-O-deacetylhelvolic acid (5), 6-O-propionyl-6-O-deacetylhelvolic acid (6), helvolic acid (7), and 1,2-dihydrohelvolic acid (8) were also identified. One-dimensional (1D), two-dimensional (2D) NMR, HRMS, and circular dichroism spectral analysis characterized the structures of the isolated compounds.


2020 ◽  
Vol 50 (2) ◽  
pp. 45-48
Author(s):  
Jens Jüttner ◽  
Nenad Krstic ◽  
Achim Müller ◽  
Monika Knuth ◽  
Christiane Thielemann

This study presents a proof of principle concept for a two-dimensional bioprinted glucose sensor on Petri dishes that allows for glucose measurements in cell culture medium. To improve bioink adhesion, the polystyrene surfaces of standard Petri dishes are activated with argon plasma, which increases roughness and hydrophilicity. The bioink containing the sensor chemistry—namely fluorescently labeled ConA/Dextran embedded in alginate microbeads—was printed on the activated Petri dishes with an extrusion-based bioprinter. The printed sensor showed good stability and adhesive properties on polystyrene. The glucose concentration was examined using a standard fluorescence microscope with filters adapted to the emission wavelength of the donor and reference dyes. The printed glucose sensor showed high sensitivity and good linearity in a physiologically relevant range of glucose concentrations.


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