Efficacy of atorvastatin therapy in prevention of postoperative atrial fibrillation in patients with ischemic heart disease

Background and Objectives: Atrial fibrillation (AF) is a frequently encountered cardiac arrhythmia which may be either symptomatic or asymptomatic. So, this study was conducted to know clinical presentation and to find out possible clinical and etiological profile of patients with AF.Material and Methods: This cross sectional study was conducted at Osh Regional Integrated Clinical Hospital, Osh Territorial City Clinical Hospital, The Kyrgyz Republic in collaboration with Janaki Medical College Teaching Hospital, Janakpurdham, Nepal. Sixty consecutive patients with AF were taken. Presenting complaints, past history, personal history was recorded. A thorough clinical examination was done, electrocardiogram, chest X-Ray posterio-anterior view, echocardiogram, thyroid function test and relevant test were done and analyzed.Results: Forty percent of the patients complained palpitation. Systemic thrombo-embolism was found in 15% of the patients. Other presenting complaints were cough, chest pain, shortness of breath, dizziness, swelling of the legs, tremors. Eighteen percent of patients presented with features of congestive cardiac failure and 30% of the patients gave history of rheumatic heart disease, 16.6% and 11.6% hypertension and ischemic heart disease respectively. Etiology-wise, rheumatic heart disease was the most common (46.6%) followed by hypertension (21.6%), ischemic heart disease (11.6%), dilated cardiomyopathy (6.6%), hyperthyroidism (5%), pneumonia (5%).Conclusion: Rheumatic heart disease, especially mitral stenosis is the most common cause of AF in this study. Systemic hypertension was next common etiology of AF, followed by ischaemic heart disease, dilated cardiomyopathy, thyroid disease. Heart failure, Systemic thromboembolism, decreased exercise tolerance are a major determinants for development of significant morbidity and mortality.Janaki Medical College Journal of Medical Sciences (2016) Vol. 4 (1): 5-12

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THE USE OF ATORVASTATIN FOR THE PREVENTION OF RECURRENT ATRIAL FIBRILLATION AFTER ELECTRICAL CARDIOVERSION IN PATIENTS WITH ISCHEMIC HEART DISEASE

Rational Pharmacotherapy in Cardiology ◽

10.20996/1819-6446-2010-6-5-657-661 ◽

2010 ◽

Vol 6 (5) ◽

pp. 657-661

Author(s):

S. N. Tereshchenko ◽

N. G. Chuich ◽

A. L. Syrkin ◽

D. A. Andreev ◽

A. V. Kolchurina ◽

...

Keyword(s):

Atrial Fibrillation ◽

Heart Disease ◽

Ischemic Heart Disease ◽

Electrical Cardioversion ◽

Ischemic Heart ◽

Recurrent Atrial Fibrillation

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Improving Medical Attention Through an Integral Care Model for Patients With Ischemic Heart Disease or Atrial Fibrillation

Revista Española de Cardiología (English Edition) ◽

10.1016/j.rec.2018.09.015 ◽

2019 ◽

Vol 72 (9) ◽

pp. 779-781

Author(s):

Román Freixa-Pamias ◽

Pedro Blanch Gràcia ◽

Maria Lluïsa Rodríguez Latre ◽

Luca Basile ◽

Pilar Sánchez Chamero ◽

...

Keyword(s):

Atrial Fibrillation ◽

Heart Disease ◽

Ischemic Heart Disease ◽

Ischemic Heart ◽

Medical Attention ◽

Care Model

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Patterns of Changes in the Psycho-emotional Background in Patients with Stable Coronary Heart Disease, Complicated By Atrial Fibrillation

Galician Medical Journal ◽

10.21802/gmj.2019.2.10 ◽

2019 ◽

Vol 26 (2) ◽

Author(s):

Lesia Serediuk ◽

Ihor Vakalyuk ◽

Halyna Kerniakevych

Keyword(s):

Atrial Fibrillation ◽

Coronary Heart Disease ◽

Heart Disease ◽

Ischemic Heart Disease ◽

Stress Level ◽

Ischemic Heart ◽

Stable Ischemic Heart Disease ◽

Constant Form ◽

Stable Coronary Heart Disease ◽

Echocardiographic Parameters

The objective is to investigate the influence of stress on the clinical and pathogenetic peculiarities of the course of stable coronary heart disease (SIHD) in conjunction with atrial fibrillation (AF). Materials and methods. The analysis of psychodiagnostic tests, labolatory and instrumental research methods in patients with and without AF has been performed. Patients were divided into three groups: group 1 – patients with stable ischemic heart disease (SIHD) with a constant form of AF (15 patients were examined), group 2 – patients with SIHD with paroxysmal form of AF (16 patients were examined), group 3 – patients with SIHD without AF (15 patients were examined). Results. According to the analysis of the data obtained, low level of stress was found in 6 (37.50%) patients with a permanent form of AF, whereas in patients without AF, it was observed in 1 (6.67%) person (p1<0.05) (p1 – the reliability of the differences in indicators relative to patients without AF). Moderate somatic disorder in women with paroxysmal AF was significantly higher than in the group of patients with a constant form of AF (p2<0.05) (p2 – the reliability of the differences in the indicators relative to patients with a constant form of AF). It is confirmed in patients with AF there are signs of the average stress level on the perceived stress level-10 (p2<0.05). Among the social factors that may have an impact on health are the influence of the media, the use of alcohol by relatives, the threat of unemployment for relatives and friends. These indicators were most often found in the group of patients with AF rather than without it (p2<0.05). Changes of ECG and echocardiographic parameters in all groups of patients were revealed. Conclusion. The association of stress with stable ischemic heart disease combined with atrial fibrillation has shown that stress disorders are associated with an increased risk of atrial fibrillation and may worsen their course and predict the risk of developing paroxysm. The dependence between the severity of clinical manifestations, psychodiagnostic tests, laboratory methods, ECG and echocardiographic parameters of the heart on the course of atrial fibrillation is proved.

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Approaches to anticoagulation therapy selection in patients with non-valvular atrial fibrillation and ischemic heart disease

CARDIOVASCULAR THERAPY AND PREVENTION ◽

10.15829/1728-8800-2016-1- ◽

2016 ◽

Vol 15 (2) ◽

pp. 83-92 ◽

Cited By ~ 1

Author(s):

N. A. Koziolova ◽

M. V. Surovtseva

Keyword(s):

Atrial Fibrillation ◽

Heart Disease ◽

Ischemic Heart Disease ◽

Anticoagulation Therapy ◽

Ischemic Heart

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Abstract 325: Readmission among Hospitalized Patients with Non-Valvular Atrial Fibrillation

Circulation Cardiovascular Quality and Outcomes ◽

10.1161/circoutcomes.5.suppl_1.a325 ◽

2012 ◽

Vol 5 (suppl_1) ◽

Author(s):

Karen E Smoyer-Tomic ◽

Kimberly Siu ◽

Barbara Johnson ◽

David R Walker ◽

Stephen Sander ◽

...

Keyword(s):

Risk Factors ◽

Atrial Fibrillation ◽

Heart Disease ◽

Ischemic Heart Disease ◽

Cerebrovascular Disease ◽

Readmission Rate ◽

Ischemic Heart ◽

Index Admission ◽

Readmission Rates ◽

Diagnosis Codes

Background: An important goal of healthcare reform is reducing the need for hospital readmissions. This study examined readmission rates, reasons for readmissions, and risk factors associated with readmissions in non-valvular atrial fibrillation (NVAF) patients, which may facilitate identification of potential gaps in care. Methods: Patients with AF hospitalizations in any diagnostic position in 2004-2009 were extracted from a large, national commercial and Medicare supplemental administrative claims database. Patients with valvular or transient causes of AF, under the age of 18 years, pregnant, or dead at discharge were excluded from the study. All patients had at least 30 days follow up from the index hospitalization discharge date. Readmission rate within 30 days of discharge date was calculated. Reasons for readmission were reported by ICD-9 diagnosis codes in the primary position. ICD-9 diagnosis codes were grouped into common acute conditions (e.g., ischemic heart disease, cerebrovascular disease) and reported. Logistic regression analyses were conducted to identify risk factors for readmission, controlling for patients’ demographic and clinical characteristics. Results: A total of 6439 patients met the study criteria. The overall 30-day readmission rate was 18.0%. Readmission rates for patients with AF as primary or secondary diagnosis in index admissions were 11.8% and 20.3%, respectively (p<0.001). Readmissions on average occurred 9.7 (SD 9.0) days from index admission discharge, with a mean readmission length of stay (LOS) of 7.4 (SD 8.0) days. The 4 most common grouped diagnoses for readmissions were AF (ICD-9 code 427.31, 10.2% of all readmissions), ischemic heart disease (IHD; 410.xx - 414.xx, 7.2%), heart failure (HF; 428.xx, 7.1%), and cerebrovascular disease (CVD; 430.xx - 438.xx, 6.0%). Longer LOS in the index admission, higher Charlson comorbidity index, and emergency room admission for the index admission all significantly increased the likelihood of having a readmission (p<0.001 in all cases). Patients discharged to home from index admission, patients with AF as primary diagnosis in index admissions, and patients living in the South region were less likely to be readmitted (p<0.01 in all cases). Conclusions: Almost one fifth of patients with NVAF were readmitted within 30 days of discharge. AF, IHD, HF, and CVD were the most common reasons for readmission. Identification of risk factors for readmission may assist healthcare providers in targeting good clinical practice aimed at improving quality of care and reducing the need for readmissions.

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Impact of ischemic heart disease and atrial fibrillation on survival after spontaneous intracerebral hemorrhage

Journal of Neurosurgery ◽

10.3171/jns/2008/108/6/1172 ◽

2008 ◽

Vol 108 (6) ◽

pp. 1172-1177 ◽

Cited By ~ 16

Author(s):

Sami Tetri ◽

Liisa Mäntymäki ◽

Seppo Juvela ◽

Pertti Saloheimo ◽

Juhani Pyhtinen ◽

...

Keyword(s):

Atrial Fibrillation ◽

Heart Disease ◽

Mortality Rate ◽

Intracerebral Hemorrhage ◽

Ischemic Heart Disease ◽

Mortality Rates ◽

Ischemic Heart ◽

University Hospital ◽

Spontaneous Intracerebral Hemorrhage

Object The well-known predictors for increased early deaths after spontaneous intracerebral hemorrhage (ICH) include the clinical and radiological severity of bleeding as well as being on a warfarin regimen at the onset of stroke. Ischemic heart disease and atrial fibrillation may also increase early deaths. In the present study the authors aimed to elucidate the role of the last 2 factors. Methods The authors assessed the 3-month mortality rate in patients with spontaneous ICH (453 individuals) who were admitted to the stroke unit of Oulu University Hospital within a period of 11 years (1993–2004). Results The 3-month mortality rate for the 453 patients was 28%. The corresponding mortality rates were 42% for the patients who had ischemic heart disease and 61% for those with atrial fibrillation on admission. The following independent predictors of death emerged after adjustment for sex and the use of warfarin or aspirin at the onset of ICH: 1) ischemic heart disease (hazard ratio [HR] 1.67, 95% confidence interval [CI] 1.12–2.48, p < 0.02); 2) atrial fibrillation on admission (HR 1.79, 95% CI 1.12–2.86, p < 0.02); 3) the Glasgow Coma Scale score on admission (HR 0.82 per unit, 95% CI 0.79–0.87, p < 0.01); 4) size of hematoma (HR 1.11 per 10 ml, 95% CI 1.07–1.16, p < 0.01); 5) intraventricular hemorrhage (HR 2.62, 95% CI 1.71–4.02, p < 0.01); 6) age (HR 1.04 per year, 95% CI 1.02–1.06, p < 0.01); and 7) infratentorial location of the hematoma (HR 1.93, 95% CI 1.26–2.97, p < 0.01). Conclusions Both ischemic heart disease and atrial fibrillation independently and significantly impaired the 3-month survival of patients with ICH.

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