scholarly journals Excessive Hypocoagulation in Therapy with Warfarin within Polypharmacy: Using online database Multi-Drug Interaction Checker and Graphic “Time-Effect-Drug Administration” to Eliminate Adverse Drug Event (Case Report)

2018 ◽  
Vol 14 (5) ◽  
pp. 687-690 ◽  
Author(s):  
G. S. Krasnov ◽  
I. V. Kazancev
Keyword(s):  
Drug Interaction ◽  
Case Report ◽  
Drug Administration ◽  
Adverse Drug Event ◽  
Time Effect ◽  
Drug Event ◽  
Online Database

Etomidate Induced Seizure: Adverse Drug Event Case Report

2020 ◽  
pp. 089719002095824
Author(s):  
Rebecca Ann Rainess ◽  
Vishal Patel ◽  
Eric Stander
Keyword(s):  
Adverse Effect ◽  
Emergency Department ◽  
Case Report ◽  
Incidence Rate ◽  
Adverse Drug Event ◽  
Shoulder Dislocation ◽  
Causality Assessment ◽  
Procedural Sedation ◽  
Drug Event ◽  
Limited Data

Objective/purpose: To report a case of etomidate induced seizure in a patient that received 0.15 mg/kg of etomidate for a procedural sedation which resolved without intervention. Summary: A 68-year-old woman presented to the emergency department with a dislocated shoulder. Etomidate was given to the patient for procedural sedation to allow the physician to reduce the shoulder dislocation. Upon administration of the medication, the patient began seizing; this lasted for about 2 minutes. No medications were needed for cessation of the seizure. Conclusion: A causality assessment determined that the adverse effect of the epileptogenic action in etomidate was possible. Limited data is available in regard to the incidence rate of this adverse effect.

scholarly journals Hallucination in a Seizure Patient Using Levetiracetam: A Case Report

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
D. R. Shakya ◽  
A. Dutta ◽  
R. Gautam
Keyword(s):  
Case Report ◽  
Antiepileptic Drug ◽  
Sodium Valproate ◽  
Adverse Drug Event ◽  
Auditory Hallucination ◽  
Drug Event ◽  
History Of ◽  
Video Eeg

Levetiracetam, a relatively new antiepileptic drug (AED), is used mainly as adjuvant and less as monotherapy of seizure. Though rare, Levetiracetam is reported to induce hallucination. To highlight the potential of this adverse drug event, we report a seizure-case that had auditory hallucination with Levetiracetam. A 32-year lady had 7-year history of unresponsive spells which increased in the last year, also occurred while asleep and were diagnosed as “generalized seizure” with video-EEG. With gradual optimization of Levetiracetam to 2250 mg, she continuously heard distressing sound of saw cutting wooden blocks. After 3-day continuous auditory hallucination, Levetiracetam had to be changed to sodium valproate.

Adverse drug event reports at the United States Food and Drug Administration Center for Veterinary Medicine

2004 ◽  
Vol 225 (4) ◽  
pp. 533-536 ◽  
Author(s):  
Victoria A. Hampshire ◽  
Frederick M. Doddy ◽  
Lynn O. Post ◽  
Teresa L. Koogler ◽  
Tina M. Burgess ◽  
...  
Keyword(s):  
United States ◽  
Veterinary Medicine ◽  
Drug Administration ◽  
Adverse Drug Event ◽  
Food And Drug Administration ◽  
The United States ◽  
Drug Event ◽  
United States Food ◽  
States Food

Completeness of serious adverse drug event reports received by the US Food and Drug Administration in 2014

2016 ◽  
Vol 25 (6) ◽  
pp. 713-718 ◽  
Author(s):  
Thomas J. Moore ◽  
Curt D. Furberg ◽  
Donald R. Mattison ◽  
Michael R. Cohen
Keyword(s):  
Drug Administration ◽  
Adverse Drug Event ◽  
Food And Drug Administration ◽  
Drug Event ◽  
The Us

scholarly journals A Case of a Dispensing Error Causing Iatrogenic Orthostatic Hypotension

2018 ◽  
Vol 13 (2) ◽  
Author(s):  
Kenneth Lam ◽  
Ann Leung ◽  
Trevor Jamieson
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Case Report ◽  
Orthostatic Hypotension ◽  
Adverse Drug Event ◽  
Multidisciplinary Team ◽  
Medication Reconciliation ◽  
Drug Event ◽  
Wrong Number ◽  
Dispensing Error

This is a case report of a patient with Parkinson’s disease and orthostatic hypotension who presented with increasing falls. We discovered that there had been a dispensing error where amiloride (Midamor®) was supplied instead of midodrine. The error was uncovered during a medication reconciliation by our pharmacist; the pharmacist noted that the pills were stamped with the wrong number and the patient’s caregiver noted that at the last refill they had, indeed, changed shape. Beyond providing the impetus for a review of orthostatic hypotension, this case also highlights an easily missed cause of an adverse drug event, and highlights the importance of the multidisciplinary team and engaged patients and caregivers. 

Severe Drug-Induced Liver Injury as an Adverse Drug Event of Antibiotics: A Case Report and Review of the Literature

Chemotherapy ◽  
2017 ◽  
Vol 62 (6) ◽  
pp. 367-373 ◽  
Author(s):  
Martin Munz ◽  
Hans Grummich ◽  
Josef Birkmann ◽  
Martin Wilhelm ◽  
Ulrike Holzgrabe ◽  
...  
Keyword(s):  
Case Report ◽  
Liver Injury ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
Adverse Drug Event ◽  
Drug Event ◽  
Review Of The Literature ◽  
Drug Induced ◽  
Drug Induced Liver Injury ◽  
Life Threatening

Drug-induced liver injury is one of the main reasons for acute liver failure. We report the case of a young patient who experienced a drug-induced liver injury resulting in life-threatening acute liver failure after treatment with different antibiotics (amoxicillin, ciprofloxacin, cefazolin, clindamycin) and acetaminophen, or a combination of these drugs. Moreover, we provide an overview of the hepatotoxic potential of these drugs.

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