scholarly journals Treatment for Chronic Sciatica: Do We Have New Evidence Showing That Discectomy Has Any Long-Term Benefits Over Conservative Care?

2021 ◽  
Vol 103 (23) ◽  
pp. e95
Author(s):  
Terence E. McIff
Keyword(s):  
Conservative Care ◽  
Chronic Sciatica ◽  
New Evidence

Reduction of major amputations in the diabetic ischaemic foot: A strategy to "take control" with conservative care as well as revascularisation

VASA ◽  
2001 ◽  
Vol 30 (Supplement 58) ◽  
pp. 6-14 ◽  
Author(s):  
Edmonds ◽  
Foster
Keyword(s):  
Natural History ◽  
Treatment Plan ◽  
Staging System ◽  
Vascular Control ◽  
New Approach ◽  
Conservative Care ◽  
Arterial Bypass ◽  
Therapeutic Footwear ◽  
Frequent Problem

The diabetic ischaemic foot has become an increasingly frequent problem over the last decade. However, we report a new approach consisting of a basic classification, a simple staging system of the natural history and a treatment plan for each stage, within a multi-disciplinary framework. This approach of "taking control" consists of two parts: 1. long-term conservative care including debridement of ulcers (to obtain wound control), eradication of sepsis (micribiological control), and provision of therapeutic footwear (mechanical control), and 2. revascularisation by angioplasty and arterial bypass (vascular control). This approach has led to a 50% reduction in the rate of major amputations in patients attending with ischaemic ulceration and absent foot pulses from 1989 to 1999 (from 4.6% to 2.3% per year). Patients who underwent angioplasty increased from 6% to 13%. Arterial bypass similarly increased from 3% to 7% of cases. However, even with an increased rate of revascularisation, 80% of patients responded to conservative care alone. This,we conclude, is an essential part of the management of all patients with ischaemic feet.

scholarly journals Supporting the development of scientific understanding when constructing an evolving explanation

2022 ◽  
Vol 4 (1) ◽  
Author(s):  
Ann M. Novak ◽  
David F. Treagust
Keyword(s):  
Scientific Explanation ◽  
Project Based Learning ◽  
Incremental Development ◽  
Freshwater Organisms ◽  
Freshwater System ◽  
New Evidence ◽  
Scientific Ideas ◽  
Over Time

AbstractWe explore how students developed an integrated understanding of scientific ideas and how they applied their understandings in new situations. We examine the incremental development of 7th grade students’ scientific ideas across four iterations of a scientific explanation related to a freshwater system. We demonstrate that knowing how to make use of scientific ideas to explain phenomena needs to be learned just as developing integrated understanding of scientific ideas needs to be learned. Students participated in an open-ended, long-term project-based learning unit, constructing one explanation over time to address, “How healthy is our stream for freshwater organisms and how do our actions on land potentially impact the water quality of the stream?” The explanation developed over several weeks as new data were collected and analyzed. Students discussed evidence by revisiting scientific ideas and including new scientific ideas. This research investigates two questions: (1) As students engage in writing a scientific explanation over time, to what extent do they develop integrated understanding of appropriate scientific ideas? and (2) When writing about new evidence, do these earlier experiences of writing explanations enable students to make use of new scientific ideas in more sophisticated ways? In other words, do earlier experiences allow students to know how to make use of their ideas in these new situations? The results indicated statistically significant effects. Through various iterations of the explanation students included richer discussion using appropriate scientific ideas. Students were also able to make better use of new knowledge in new situations.

Questioning the effect of the real exchange rate on growth: new evidence from Mexico

2021 ◽  
Vol 9 (2) ◽  
pp. 253-269
Author(s):  
Florencia Médici ◽  
Augustín Mario ◽  
Alejandro Fiorito
Keyword(s):  
Economic Growth ◽  
Exchange Rate ◽  
Real Exchange Rate ◽  
Public Expenditure ◽  
Institutional Arrangements ◽  
Relative Price ◽  
The Real ◽  
Empirical Results ◽  
New Evidence

This study provides new evidence showing that the real exchange rate (RER) does not play an important role in the growth of Mexican GDP. Economic growth is not an automatically predetermined result of relative price correction, and it is important to consider distinctive aspects of national institutional arrangements (fiscal and monetary, for example) for understanding theoretical causality of demand. The empirical results show public expenditure is an overlooked variable in regressions where the exchange rate affects product growth. After incorporating public expenditure, the RER impact on growth becomes insignificant. For its part, public expenditure has a positive and significant effect on GDP in the long term. The RER does not lead to greater GDP since exports are not stimulated through price.

The Evolution and Importance of Public Credit

2011 ◽  
Author(s):  
David Stasavage
Keyword(s):  
Interest Rates ◽  
Early Modern Europe ◽  
Access To Credit ◽  
Public Credit ◽  
The Difference ◽  
City States ◽  
The Cost ◽  
Territorial States ◽  
New Evidence

This chapter examines why access to credit was important for European states and provides extensive new evidence on the evolution of public credit across five centuries, from 1250 to 1750. The ability to borrow was critical in medieval and early modern Europe because it allowed states to participate in wars, either defensive or offensive. In order to better understand this fact, the chapter analyzes the movement that took place from compulsory to paid service for soldiers, along with opportunities to finance wars through current taxation. It also explains when states first borrowed long-term and measures the cost of borrowing, focusing on interest rates based on nominal rates at issue when these are available, and based on the fiscal proxy when they are not. The chapter highlights the difference between city-states and territorial states, with the former enjoying an apparent financial advantage that allowed them to begin borrowing earlier and to obtain access to lower-cost finance.

Acupuncture in Neurological Disorders: An Evidence-Based Overview

2020 ◽  
pp. 449-494
Author(s):  
Alexandra Dimitrova
Keyword(s):  
Neurological Disorders ◽  
Large Scale ◽  
Healthcare Providers ◽  
Evidence Based ◽  
Tunnel Syndrome ◽  
Meta Analyses ◽  
New Evidence ◽  
Common Misconceptions

Over the past 20 years acupuncture has been rapidly gaining in popularity both in clinical practice and in research. New evidence for the benefits of acupuncture in various disorders is emerging seemingly every week, and recent large-scale systematic reviews and meta-analyses have suggested that acupuncture’s benefits in pain conditions can be maintained long term. At present the strongest evidence for acupuncture in the treatment of neurological disorders is in the fields of migraine, tension headaches, diabetic neuropathy, carpal tunnel syndrome, and Bell’s palsy. Recent trials suggest that acupuncture may be used as an adjunct in stroke rehabilitation and in improving the quality of life in patients with Parkinson’s disease and dementia. Despite recent mechanistic research advances, much remains unknown about acupuncture’s mechanism of action and there are common misconceptions about the origins of modern-day acupuncture. As acupuncture is being rapidly integrated into mainstream medical practice and increasingly being sought by patients, healthcare providers and neurologists in particular need to be educated about its applications and benefits for various neurological disorders. Our hope is that this chapter will serve toward this educational goal.

Sedimentary facies on the rises and slopes of passive continental margins

1980 ◽  
Vol 294 (1409) ◽  
pp. 169-176 ◽  
Keyword(s):  
Sediment Transport ◽  
Debris Flows ◽  
Thermohaline Circulation ◽  
Dominant Role ◽  
Sedimentary Facies ◽  
Turbidity Currents ◽  
Continental Margins ◽  
Passive Margins ◽  
New Evidence

JOIDES drilling results provide new evidence concerning facies patterns on evolving passive margins that strengthens and extends hypotheses constructed from studies of morphology, seismic reflexion data and shallow samples on modern margins, and from field geologic studies of uplifted ancient margins. On the slopes and rise, gravity-controlled mechanisms - turbidity currents, debris flows, slides and the like - play the dominant role in sediment transport over the long term, but when clastic supplies are reduced, as for example during rapid transgressions, then oceanic sedimentation and the effects of thermohaline circulation become important. Sedimentary facies models used as the basis of unravelling tectonic complexities of some deformed margins, for example in the Mesozoic Tethys, may be too simplistic in the light of available data from modern continental margins.

Culture and Love of Money: Evidence From the Iberian Peninsula and U.S. Hispanic Residents

2019 ◽  
Vol 41 (4) ◽  
pp. 550-571 ◽  
Author(s):  
Tânia M. G. Marques ◽  
Cátia Crespo ◽  
Sanjay T. Menon ◽  
Jorge F. S. Gomes ◽  
Sonia R. Gilmartin
Keyword(s):  
Organizational Behavior ◽  
Cultural Values ◽  
Structural Equation ◽  
Equation Modeling ◽  
Organizational Policies ◽  
Love Of Money ◽  
The Love Of Money ◽  
Different Cultures ◽  
New Evidence

Money has become a key element in any kind of relationship, both within and outside national borders. However, different cultures may give money a distinct role in society. Hence, the current study investigated the relationship between cultural values and the love of money. A survey was carried out to collect data from 813 individuals in total, 613 Spanish and Portuguese and 200 U.S. Hispanic. The hypotheses were tested through structural equation modeling (SEM) with partial least squares (PLS). Despite several differences in the results of both samples, Iberian and North American Hispanic samples have in common the fact that long-term orientation and indulgence positively influence the love of money budget factor. This study presents new evidence and reinforces fresh insights for managers to better understand their staff worldwide. Furthermore, organizational policies and practices related to ethics and organizational behavior should be adequately implemented, according to the love of money perception of members of their teams.

scholarly journals Endocrine aspects of anabolic steroids

1997 ◽  
Vol 43 (7) ◽  
pp. 1289-1292 ◽  
Author(s):  
F C W Wu
Keyword(s):  
Androgen Receptor ◽  
Anabolic Steroids ◽  
Muscle Size ◽  
Anabolic Action ◽  
Life Threatening ◽  
Disease Risks ◽  
Women And Children ◽  
Androgenic Anabolic Steroids ◽  
New Evidence

Abstract Understanding of the mechanism of androgen action has been enhanced by advances in knowledge on the molecular basis of activation of the androgen receptor and the importance of tissue conversion of circulating testosterone to dihydrotestosterone and estradiol. New evidence supports the view that supraphysiological doses of anabolic steroids do have a definite, positive effect on muscle size and muscle strength. However, the nature of the anabolic action of androgens on muscle is currently unclear and may involve mechanisms independent of the androgen receptor. The dose–response relationships of anabolic actions vs the potentially serious risks to health of androgenic-anabolic steroids (AAS) use are still unresolved. Most of the adverse effects of AAS are reversible but some are permanent, particularly in women and children. The reported incidence of acute life-threatening events associated with AAS abuse is low, but the actual risk may be underrecognized or underreported; the exact incidence is unknown. The long-term consequences and disease risks of AAS to the sports competitor remain to be properly evaluated.

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