scholarly journals Fundamental theory of void fraction of cohesive spheres with size distribution and its application to multi component mixture system

2012 ◽  
Vol 120 (1397) ◽  
pp. 21-24 ◽  
Author(s):  
Yutaka AIKAWA ◽  
Maki INOUE ◽  
Etsuo SAKAI
Keyword(s):  
Size Distribution ◽  
Void Fraction ◽  
Fundamental Theory ◽  
Component Mixture ◽  
Mixture System

scholarly journals Fundamental theory of void fraction of cohesive spheres with logarithmic normal size distribution

2012 ◽  
Vol 120 (1406) ◽  
pp. 417-419 ◽  
Author(s):  
Yutaka AIKAWA ◽  
Michitaka SUZUKI ◽  
Daiki ATARASHI ◽  
Etsuo SAKAI
Keyword(s):  
Size Distribution ◽  
Void Fraction ◽  
Fundamental Theory

scholarly journals Combined Amoebicidal Effect of Atorvastatin and Commercial Eye Drops against Acanthamoeba castellanii Neff: In Vitro Assay Based on Mixture Design

Pathogens ◽  
2020 ◽  
Vol 9 (3) ◽  
pp. 219 ◽  
Author(s):  
Ines Sifaoui ◽  
Eulalia Capote Yanes ◽  
María Reyes-Batlle ◽  
Rubén L. Rodríguez-Expósito ◽  
José E. Piñero ◽  
...  
Keyword(s):  
Acanthamoeba Castellanii ◽  
Acanthamoeba Keratitis ◽  
Eukaryotic Cell ◽  
Resistance Pattern ◽  
Eye Drops ◽  
Current Standard ◽  
Component Mixture ◽  
Vitro Assay ◽  
Mixture System

The establishment of an effective therapeutic agent against Acanthamoeba keratitis (AK), remains until present, an issue to be solved due to the existence of a cyst stage in the life cycle of Acanthamoeba. Moreover, the effectiveness of the current standard therapeutic agents varies depending on the tested Acanthamoeba strains and its resistance pattern. In the present study, two 10-point augmented simplex-centroid designs were used to formulate a three-component mixture system using water, atorvastatin, and Diclofenaco-lepori or Optiben. The amoebicidal effects and in vitro-induced toxicity in a eukaryotic cell line were determined for all experiments. The optimal mixture to inhibit the parasite without inducing toxicity was established in the first plan as 30% Optiben, 63.5% atorvastatin, and 3.1% water. As for the second experimental design, the optimal mixture to inhibit Acanthamoeba with lower toxicity effect was composed of 17.6% Diclofenaco-lepori and 82.4% atorvastatin.

Numerical Simulation of Subcooled Flow Boiling Using a Bubble Tracking Method

2016 ◽  
Author(s):  
Tomio Okawa ◽  
Naoki Miyano ◽  
Kazuhiro Kaiho ◽  
Koji Enoki
Keyword(s):  
Numerical Simulation ◽  
Size Distribution ◽  
Void Fraction ◽  
Bubble Size ◽  
Flow Boiling ◽  
Bubble Nucleation ◽  
Bubble Size Distribution ◽  
Subcooled Flow Boiling ◽  
Tracking Method ◽  
Subcooled Flow

The process of bubble nucleation in subcooled flow boiling was visualized using a high speed camera to show that the bubble size can be significantly different between the nucleation sites. However, the bubble size is usually assumed constant in the numerical simulation of subcooled flow boiling. To explore the effect of the bubble size distribution on the void fraction in subcooled flow boiling, numerical simulations were performed using a bubble tracking method in which the size and position of each bubble are calculated individually using a Lagrangian coordinates. In the present simulation, the void fraction was greater when the bubble size distribution was taken into consideration. Since the bubble tracking method requires many correlations, further improvement is necessary. The present numerical results however indicate that the bubble size distribution should be taken in to consideration to evaluate the void fraction in subcooled flow boiling accurately.

Application of a Fiber Optic Probe to High Void Fraction Air/Water Flow

2008 ◽  
Author(s):  
A. J. Pertzborn ◽  
W. C. Smith
Keyword(s):  
Size Distribution ◽  
Water Flow ◽  
Void Fraction ◽  
Droplet Size ◽  
Fiber Optic ◽  
Droplet Size Distribution ◽  
Spray Nozzle ◽  
Fiber Optic Probe ◽  
Flow Measurements ◽  
Optic Probe

Successful development of CFD models for droplet flows is aided by knowledge of the droplet size distribution in the flow, but current instrumentation for measuring droplet size is limited. In an attempt to improve the quality of data collected, fiber optic probe (FOP) technology was investigated. A spray nozzle injected water droplets into an air stream to create a high void fraction droplet flow. Measurements were acquired with the spray nozzle at two different locations upstream of the FOP position. Mean droplet velocity measurements were acquired using laser Doppler velocimetry (LDV) at the FOP position. The droplet size distribution at the probe location was determined by using both the FOP and LDV measurements. The initial results indicate that FOP technology can successfully measure the droplet size distribution in a high void fraction air/water flow and it should be further developed for this application.

Concentration addition prediction for a multiple-component mixture containing no effect chemicals

2015 ◽  
Vol 7 (23) ◽  
pp. 9912-9917 ◽  
Author(s):  
Ling Liu ◽  
Shu-Shen Liu ◽  
Mo Yu ◽  
Jin Zhang ◽  
Fu Chen
Keyword(s):  
Prediction Method ◽  
Concentration Effect ◽  
Concentration Addition ◽  
Component Mixture ◽  
Blind Zone ◽  
Multiple Component ◽  
Mixture System

A concentration-effect prediction method for a mixture with a predictive blind zone (PBZone) in a mixture system containing no-effect chemicals.

Jet Fuel Cavitation in a Converging Diverging Nozzle

2007 ◽  
Author(s):  
Michael P. Davis ◽  
Patrick F. Dunn ◽  
Flint O. Thomas
Keyword(s):  
Void Fraction ◽  
Flow Rate ◽  
High Speed ◽  
Primary Source ◽  
Phase Region ◽  
Bubble Nucleation ◽  
Two Phase ◽  
Component Mixture ◽  
Fuel Gas ◽  
Nozzle Flows

The focus of this research proposal is the experimental characterization of fuel cavitation in flow through a converging-diverging nozzle. Cavitation of fuel presents additional complexities (as compared to that in water) because fuel is a multi-component mixture. In any practical engineering environment, large quantities of solid microparticles are resident in the fuel. Gas nuclei trapped on these microparticles has been shown to enhance bubble production in water, and their effect on fuel cavitation is an issue that will be investigated. Measurements also will be made with cavitating water for comparison. A converging-diverging nozzle was chosen as the means for producing cavitation because its type of area constriction is similar to other flow devices such as valves and pumps. Cavitating C-D nozzle flows also have been modeled extensively in the literature. The data that will be acquired include axial pressure profiles, nozzle flow rate, high-speed images of the cavitating region, axial void fraction profiles, and axial velocity profiles. Pressure, velocity, and flow rate data will be used to determine the pressure ratios and limiting mass flow rates when the nozzle is choked. High speed images will be used to identify the structures present in the two-phase region (whether the gaseous voids are spherical bubbles or amorphous slugs. Axial void fraction data will provide information on gas evolution in the flow. Experimental data for cavitating nozzle flows are limited to water cases where bubble nucleation is not a primary source of the two-phase mixture. The proposed research hopes to provide detailed pressure, void-fraction, and velocity measurements for comparison with existing models. The main differences between fuel and water cavitation will be highlighted.

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