scholarly journals Prophylactic vaccines against cancers of non-infectious origin: a dream or a real possibility?

2021 ◽  
Vol 29 (4) ◽  
pp. 247-258
Author(s):  
Vladimír Vonka ◽  
Ivan Hirsch
Author(s):  
Avishag Edri ◽  
Henriette Dahan-Kalev

In Israel, like the rest of Western society, women are still largely responsible for childcare and housework. In homeschooling families, this division is even more prominent. This article explores homeschooling mothers’ perspective on role division. Using the auto-ethnographic-phenomenological approach to qualitative research of individual perceptions and experiences, I recruited a purpose-focused sample of 27 homeschooling mothers. Using interviews and personal logs (or diaries), I obtained data that underwent thematic analysis. The study findings indicate that mothers like being with their kids and that most of them would not want to change places with their partner, but the question arises as to whether there is a real possibility of choosing.


2020 ◽  
Vol 12 (3) ◽  
pp. 189
Author(s):  
Sebastian Gäb

When we were on the subway back from his lecture, I said to Robin: “I’m not sure there actually are any religious fictionalists.” We keep talking about them in papers and lectures, acting as if fictionalism in religion is a real possibility, but to be honest, I haven’t been able to spot one in the wild so far. The only potential candidate who comes to mind is Don Cupitt, who wrote things like: “I still pray and love God, even though I fully acknowledge that no God actually exists.”[1] Perhaps this is as fictionalist as it gets. But then again, Cupitt never explicitly declared himself a fictionalist (at least to my knowledge). Moreover, on other occasions he sounds more like an expressivist than a fictionalist, e.g. when he says: “The Christian doctrine of God just is Christian spirituality in coded form.”[2] So, if there are any actual fictionalists out there, please step forward.[1] Don Cupitt, After God: The Future of Religion (Basic Books, 1997), 85.[2] Don Cupitt, Taking leave of God (SCM Press, 1980), 14.


1992 ◽  
Vol 26 (9-11) ◽  
pp. 2149-2152 ◽  
Author(s):  
A. Grappelli ◽  
L. Campanella ◽  
E. Cardarelli ◽  
F. Mazzei ◽  
M. Cordatore ◽  
...  

Experiments on the real possibility of employing microorganisms to capture inorganic polluting substances, mainly heavy metals from urban and industrial wastes, are running using bacteria biomass. Many strains of Arthrobacter spp., gram-negative bacteria, diffused in the soil also inacondition of environmental stresses, have been proved to be particulary effective in heavy metal capture (Cd, Cr, Pb, Cu, Zn). The active and passive processes in accumulation of metals by bacteria were studied. Our experiments have been done on fluid biomass and on a membrane both for practical use and for an easy recovery.


2020 ◽  
Vol 09 ◽  
Author(s):  
Subba Rao Toleti

: The review is an attempt to introduce the readers in brief about biofilms and their implications as well as some new perceptions in biotechnology. Biofilms are adherent microbial communities, which are developed on submerged surfaces in aquatic environments. Biofilms play a significant role in exopolymer production, material deterioration and also cause harmful infections. Further, the role of corrosion causing biofilm bacteria in deterioration of different materials, microbial biofilms and their enzymatic processes in reducing the toxicity of pollutants in industrial effluents are elaborated, along with clean technologies for wastewater treatment. Biotechnology is defined as any technological application that uses biological systems to synthesize or modify products or processes. The applications include biochemical processes, medical care, cell and tissue culture as well as synthetic biology and others. Synthetic biology details about the design, construction of new biological components and systems for useful purposes. Finally, to overcome the limitations that are inherent to the use of cellular host’s, cell-free systems as critical platforms for synthetic biology applications. This mini-review also mentions about new diagnostic products based on enzymes, monoclonal antibodies and engineered proteins as well as novel prophylactic vaccines.


2012 ◽  
Vol 40 (1) ◽  
pp. 69-88
Author(s):  
Eliot Olivier

Political controversies in New South Wales and Canada recently have focused public attention on the constitutional practice of proroguing parliament. They have also shone a light on two lingering areas of uncertainty that surround its operation under the Commonwealth Constitution. This article seeks to clarify these two muddy areas of the law concerning prorogation. The first is the effect of prorogation on the Senate and its committees. Since Federation, the Senate has purported to authorise its committees to continue to function notwithstanding a prorogation of the Parliament. However, it is argued that this practice is unsupported by the provisions of the Constitution and the Senate has no such power. Second, the article examines the operation of the conventions that constrain the Governor-General's power to prorogue. Prorogation generally is exercised on the advice of the Prime Minister. However, this article contends that where a Prime Minister seeks to prorogue Parliament to avoid a vote of no confidence, the Governor-General will have a discretion to reject the advice. It may also be open to the Governor-General to reject an advice to prorogue where the purpose is to avoid scrutiny of a fundamental constitutional illegality. In Australia, the uncertainties that surround prorogation, coupled with the now precarious political landscape in Canberra, create the very real possibility of a prorogation crisis at the Commonwealth level. This article provides a response to these uncertainties. In doing so it offers a solution to how a prorogation crisis can be resolved, whilst maintaining the fine balance of power in our constitutional system.


Author(s):  
Jessica Leech

In the Postulates of Empirical Thinking, a section of the Critique of Pure Reason, Kant presents an account of the content and role of our concept of real possibility in terms of formal conditions of experience. However, much later in the Critique he introduces the idea of a material condition of possibility. What is this material condition of possibility, and how does it fit with the conception of possibility in terms of formal conditions? This essay argues that the key to answering these questions—as well as to understanding Kant’s criticism of rational theology, in which the discussion of the material condition of possibility appears—is Kant’s account of how we can individuate objects.


Vaccines ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 668
Author(s):  
Howard Donninger ◽  
Chi Li ◽  
John W. Eaton ◽  
Kavitha Yaddanapudi

The advent of cancer immunotherapy has revolutionized the field of cancer treatment and offers cancer patients new hope. Although this therapy has proved highly successful for some patients, its efficacy is not all encompassing and several cancer types do not respond. Cancer vaccines offer an alternate approach to promote anti-tumor immunity that differ in their mode of action from antibody-based therapies. Cancer vaccines serve to balance the equilibrium of the crosstalk between the tumor cells and the host immune system. Recent advances in understanding the nature of tumor-mediated tolerogenicity and antigen presentation has aided in the identification of tumor antigens that have the potential to enhance anti-tumor immunity. Cancer vaccines can either be prophylactic (preventative) or therapeutic (curative). An exciting option for therapeutic vaccines is the emergence of personalized vaccines, which are tailor-made and specific for tumor type and individual patient. This review summarizes the current standing of the most promising vaccine strategies with respect to their development and clinical efficacy. We also discuss prospects for future development of stem cell-based prophylactic vaccines.


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