scholarly journals Maternal coffee intake and the risk of bleeding in early pregnancy: a cross-sectional analysis

2019 ◽  
Author(s):  
Hansol Choi ◽  
Seul Koo ◽  
Hyun-Young Park
Keyword(s):  
Pregnant Women ◽  
Early Pregnancy ◽  
Coffee Consumption ◽  
Consumption Patterns ◽  
Caffeine Intake ◽  
Cross Sectional ◽  
Coffee Drinking ◽  
Risk Of Bleeding ◽  
Sectional Analysis ◽  
Coffee Drinker

Abstract Background: Caffeine can easily cross the placenta, and maternal caffeine intake, thus, has an effect on fetal growth. However, it is still unclear whether coffee consumption is an independent risk factor for bleeding in early pregnancy. The objective of this study was to examine the association between pre-pregnancy coffee consumption patterns and the risk of bleeding in early pregnancy. Methods: A cross-sectional analysis was conducted among 3,510 pregnant women from the Korean Pregnancy Outcome Study who underwent baseline examination between 2013 and 2017 and for whom the results of the pregnancy were available. Coffee consumption patterns before pregnancy were examined using a questionnaire. The participants were classified according to the frequency of coffee consumption into seldom (<1 cup/week), light (<1 cup/day), moderate (1 cup/day), and heavy coffee drinker (≥2 cups/day) groups. Bleeding in early pregnancy was defined as the occurrence of vaginal bleeding in the first 20 weeks of pregnancy. Multiple logistic regression models were applied to examine the association between pre-pregnancy coffee consumption and the risk of bleeding in early pregnancy, after adjusting for age, body mass index, systolic blood pressure, cigarette smoking and alcohol consumption behavior, previous and current physical activity levels, stress levels, history of depression, presence of antenatal depressive symptoms during the first trimester, type of emesis, parity, and the number of livebirths, stillbirths, miscarriages, and abortions. Odds ratios among light, moderate, and heavy coffee drinkers were determined through comparisons with the seldom coffee drinker group. Results: Women who were light, moderate, and heavy coffee drinkers before pregnancy had adjusted odds ratios of 1.086, 1.225, and 1.358, respectively, for bleeding in early pregnancy. However, the association between coffee consumption and the risk of miscarriage or stillbirth was not significant. Conclusions: Our results showed that heavy coffee drinking was independently associated with a higher risk of bleeding in early pregnancy among pregnant Korean women, indicating that caffeine intake before conception and during pregnancy should be reduced. Our study highlights the need for nutritional interventions for healthy coffee drinking among pregnant women in Korea.

scholarly journals Maternal coffee intake and the risk of bleeding in early pregnancy: a cross-sectional analysis

2020 ◽  
Author(s):  
Hansol Choi ◽  
Seul Koo ◽  
Hyun-Young Park
Keyword(s):  
Pregnant Women ◽  
Early Pregnancy ◽  
Coffee Consumption ◽  
Consumption Patterns ◽  
Caffeine Intake ◽  
Cross Sectional ◽  
Coffee Drinking ◽  
Risk Of Bleeding ◽  
Sectional Analysis ◽  
Coffee Drinker

Abstract Background: Caffeine can easily cross the placenta, and maternal caffeine intake, thus, has an effect on fetal growth. However, it is still unclear whether coffee consumption is an independent risk factor for bleeding in early pregnancy. The objective of this study was to examine the association between pre-pregnancy coffee consumption patterns and the risk of bleeding in early pregnancy. Methods: A cross-sectional analysis was conducted among 3,510 pregnant women from the Korean Pregnancy Outcome Study who underwent baseline examination between 2013 and 2017 and for whom the results of the pregnancy were available. Coffee consumption patterns before pregnancy were examined using a questionnaire. The participants were classified according to the frequency of coffee consumption into seldom (<1 cup/week), light (<1 cup/day), moderate (1 cup/day), and heavy coffee drinker (≥2 cups/day) groups. Bleeding in early pregnancy was defined as the occurrence of vaginal bleeding in the first 20 weeks of pregnancy. Multiple logistic regression models were applied to examine the association between pre-pregnancy coffee consumption and the risk of bleeding in early pregnancy, after adjusting for age, body mass index, systolic blood pressure, cigarette smoking and alcohol consumption behavior, previous and current physical activity levels, stress levels, history of depression, presence of antenatal depressive symptoms during the first trimester, type of emesis, parity, and the number of livebirths, stillbirths, miscarriages, and abortions. Odds ratios among light, moderate, and heavy coffee drinkers were determined through comparisons with the seldom coffee drinker group. Results: Women who were light, moderate, and heavy coffee drinkers before pregnancy had adjusted odds ratios of 1.086, 1.225, and 1.358, respectively, for bleeding in early pregnancy. However, the association between coffee consumption and the risk of miscarriage or stillbirth was not significant. Conclusions: Our results showed that heavy coffee drinking was independently associated with a higher risk of bleeding in early pregnancy among pregnant Korean women, suggesting that caffeine intake before conception and during pregnancy should be reduced. Our study highlights the need for nutritional interventions for healthy coffee drinking among pregnant women in Korea. Keywords: caffeine, coffee consumption, fetus, placenta, pregnancy

scholarly journals Maternal coffee intake and the risk of bleeding in early pregnancy: A cross-sectional analysis

2020 ◽  
Author(s):  
Hansol Choi ◽  
Seul Koo ◽  
Hyun-Young Park
Keyword(s):  
Body Mass Index ◽  
Pregnant Women ◽  
Early Pregnancy ◽  
Coffee Consumption ◽  
Consumption Patterns ◽  
Caffeine Intake ◽  
Cross Sectional ◽  
Coffee Drinking ◽  
Risk Of Bleeding ◽  
Sectional Analysis

Abstract Background: Caffeine can easily cross the placenta, and maternal caffeine intake, thus, has an effect on fetal growth. However, it is still unclear whether coffee consumption is an independent risk factor for bleeding in early pregnancy. The objective of this study was to examine the association between pre-pregnancy coffee consumption patterns and the risk of bleeding in early pregnancy. Methods: A cross-sectional analysis was conducted among 3,510 pregnant women from the Korean Pregnancy Outcome Study who underwent baseline examination and for whom the results of the pregnancy were available. Coffee consumption patterns before pregnancy were examined using a questionnaire. The participants were classified according to the frequency of coffee consumption into seldom (<1 cup/week), light (<1 cup/day), moderate (1 cup/day), and heavy coffee drinker (≥2 cups/day) groups. Bleeding in early pregnancy was defined as the occurrence of vaginal bleeding in the first 20 weeks of pregnancy. Multiple logistic regression models were applied to examine the association between pre-pregnancy coffee consumption and the risk of bleeding in early pregnancy, after adjusting for age, body mass index (BMI), systolic blood pressure, cigarette smoking and alcohol consumption behavior, previous and current physical activity levels, stress levels, history of depression, antenatal depressive symptoms during the first trimester, type of emesis, parity, and the number of livebirths, stillbirths, miscarriages, and abortions. Results: Women who were light, moderate, and heavy coffee drinkers before pregnancy had adjusted ORs of 1.086, 1.225, and 1.358, respectively, for bleeding in early pregnancy. In a fully adjusted model, heavy coffee drinkers showed a significantly higher risk of bleeding in early pregnancy, even in women aged 35 years and younger (OR 1.680) and in those with a normal body mass index (OR 1.389), who were at relatively low risk for pregnancy-related complications. Conclusions: Our results showed that heavy coffee drinking was independently associated with a higher risk of bleeding in early pregnancy among pregnant Korean women, suggesting that caffeine intake before conception and during pregnancy should be reduced. Our study highlights the need for nutritional interventions for healthy coffee drinking among pregnant women in Korea.

scholarly journals Maternal coffee intake and the risk of bleeding in early pregnancy: A cross-sectional analysis

2020 ◽  
Author(s):  
Hansol Choi ◽  
Seul Koo ◽  
Hyun-Young Park
Keyword(s):  
Body Mass Index ◽  
Pregnant Women ◽  
Early Pregnancy ◽  
Coffee Consumption ◽  
Consumption Patterns ◽  
Caffeine Intake ◽  
Cross Sectional ◽  
Coffee Drinking ◽  
Risk Of Bleeding ◽  
Sectional Analysis

Abstract Background: Caffeine can easily cross the placenta, and maternal caffeine intake, thus, has an effect on fetal growth. However, it is still unclear whether coffee consumption is an independent risk factor for bleeding in early pregnancy. The objective of this study was to examine the association between pre-pregnancy coffee consumption patterns and the risk of bleeding in early pregnancy. Methods: A cross-sectional analysis was conducted among 3,510 pregnant women from the Korean Pregnancy Outcome Study who underwent baseline examination and for whom the results of the pregnancy were available. Coffee consumption patterns before pregnancy were examined using a questionnaire. The participants were classified according to the frequency of coffee consumption into seldom (<1 cup/week), light (<1 cup/day), moderate (1 cup/day), and heavy coffee drinker (≥2 cups/day) groups. Bleeding in early pregnancy was defined as the occurrence of vaginal bleeding in the first 20 weeks of pregnancy. Multiple logistic regression models were applied to examine the association between pre-pregnancy coffee consumption and the risk of bleeding in early pregnancy, after adjusting for age, body mass index (BMI), systolic blood pressure, cigarette smoking and alcohol consumption behavior, previous and current physical activity levels, stress levels, history of depression, antenatal depressive symptoms during the first trimester, type of emesis, parity, and the number of livebirths, stillbirths, miscarriages, and abortions. Results: Women who were light, moderate, and heavy coffee drinkers before pregnancy had adjusted ORs of 1.086, 1.225, and 1.358, respectively, for bleeding in early pregnancy. In a fully adjusted model, heavy coffee drinkers showed a significantly higher risk of bleeding in early pregnancy, even in women aged 35 years and younger (OR 1.680) and in those with a normal body mass index (OR 1.389), who were at relatively low risk for pregnancy-related complications. Conclusions: Our results showed that heavy coffee drinking was independently associated with a higher risk of bleeding in early pregnancy among pregnant Korean women, suggesting that caffeine intake before conception and during pregnancy should be reduced. Our study highlights the need for nutritional interventions for healthy coffee drinking among pregnant women in Korea.

scholarly journals Maternal coffee intake and the risk of threatened abortion

2019 ◽  
Author(s):  
Hansol Choi ◽  
Seul Koo ◽  
Hyun-Young Park
Keyword(s):  
Pregnant Women ◽  
Coffee Consumption ◽  
Caffeine Intake ◽  
Consumption Pattern ◽  
Coffee Intake ◽  
Cross Sectional ◽  
Logistic Regression Models ◽  
Coffee Drinking ◽  
Before And After ◽  
Threatened Abortion

Abstract Background Maternal caffeine intake has an effect on fetal growth through cross the placenta freely. The objective of this study is to examine the association of pre-pregnancy coffee consumption pattern with the risk of threatened abortion. Methods A cross-sectional analysis was conducted for a total of 4,111 pregnant women who completed baseline examination for the Korean Pregnancy Outcome Study between 2013 and 2017. Coffee consumption pattern before pregnancy was measured by a questionnaire. The frequency of coffee consumption was divided into seldom (<1 cup/week), light (<1 cup/day), moderate (1 cup/day), and heavy coffee drinkers (≥2 cups/day). Threatened abortion was defined as the occurrence of vaginal bleeding in the first 20 weeks of pregnancy. Multiple logistic regression models were applied to examine the association between pre-pregnancy coffee consumption and the risk of threatened abortion, after adjusting for age, body mass index, systolic blood pressure, smoking, drinking, physical activity before and after pregnancy, stress level, history of depression, and reproductive information. Results Women with heavy coffee drinking were at increased odds for having threatened abortion in unadjusted model (odds ratio [OR], 1.271; 95% confidence interval [CI], 1.008 to 1.602). Compared to women with seldom coffee drinkers, the fully adjusted ORs for the risk of threatened abortion were significant in moderate (OR, 1.420; 95% CI, 1.001 to 2.014) and heavy coffee drinkers (OR, 1.750; 95% CI, 1.156 to 2.651). Conclusions Heavy coffee drinking was independently associated with a higher risk of threatened abortion among Korean pregnant women.

scholarly journals Fetal Echocardiography:Short Term Profile from Shahid Gangalal National Heart Centre, Kathmandu, Nepal

2016 ◽  
Vol 13 (1) ◽  
pp. 9-12
Author(s):  
Sudhir Regmi ◽  
Deewakar Sharma
Keyword(s):  
Pregnant Women ◽  
Congenital Heart ◽  
Fetal Echocardiography ◽  
Tertiary Care ◽  
Outcome Data ◽  
Cross Sectional ◽  
Vitro Fertilization ◽  
History Of ◽  
Sectional Analysis

Background and Aims: Fetal echocardiography is helpful in early detection of Congenital Heart Disease. Our study was conducted to evaluate the most common indications of referral and outcome in a tertiary-care fetal echocardiography practice.Methods: A Cross-sectional analysis of all pregnant women referred by obstetricians to cardiology unit for fetal echocardiography over a 1-year period (July 2014 and July 2015) was performed. The primary indications for referral for fetal echocardiography were obtained from the obstetric referral forms. Outcome data were extracted from performa containing client’s demographic, physical examination and the fetal echocardiograhic data. Postnatal Echocardiography was advised to all cases having positive echocardiographic finding.Results: A series of 251 fetal cardiac studies were reviewed. Average gestational age was 25.6 weeks (range, 18 to 38 weeks). Thirty-eight (15.1%) pregnant women had abnormal fetal cardiac findings. The most common referral for fetal cardiac scan was related to maternal indications (48.6%). Other indications were abnormal prenatal fetal findings in ultrasonography (23.1%), family history of CHD (12%), general screening (15.5%), and follow up of IVF (In-vitro fertilization) (0.8%). The highest yield of significant abnormal findings was there among patients referred with abnormal prenatal fetal finding in ultrasonography (47%).Conclusion: Majority of referral were for abnormal prenatal ultrasonographic findings. So, fetal Echocardiography is an important part of overall management of the pregnancy at risk for producing an infant with congenital heart disease.Nepalese Heart Journal 2016; 13(1): 9-12

scholarly journals Assessment of Thyroid Function in Early Pregnancy

2018 ◽  
Vol 19 (2) ◽  
pp. 98
Author(s):  
Mohammad Saifur Rahman ◽  
Sadia Sultana ◽  
Ayesha Nazneen
Keyword(s):  
Pregnant Women ◽  
Thyroid Function ◽  
Early Pregnancy ◽  
Correct Diagnosis ◽  
First Trimester ◽  
Military Hospital ◽  
Thyroid Disorders ◽  
Thyroid Disorder ◽  
Cross Sectional ◽  
In Pregnancy

<p><strong>Objectives:  </strong>Thyroid disorders are commonly observed in pregnancy. Thyroid hormones play an important role in embryogenesis and fetal development. The fetus is completely dependent on the mother for thyroid hormone in first trimester. About 10% of all pregnant women can be affected by thyroid disorders during pregnancy. Thyroid function abnormalities in pregnancy are a challenge for the concerned physicians.  The objective of this study was to assess the maternal thyroid function in first trimester of pregnancy.</p><p><strong>Patients and Methods: </strong>A descriptive cross sectional study was carried out at the Combined Military Hospital (CMH), Dhaka over a period of one year from January 2013 to December 2013 to see the serum FT<sub>3</sub>, FT<sub>4</sub>, TSH, thyroid antibodies level and common thyroid disorders in pregnancy. A total of 138 pregnant women in their first trimester (up to 12 weeks) of pregnancy with an age range of 18-35 years were enrolled in this study. Pregnant women with known thyroid disorder and on treatment and pregnancy more than three months were excluded. Measurement of serum FT<sub>3</sub>, FT<sub>4</sub>, TSH, Anti TPO-Ab and Anti TG-Ab were done in each patient at the time of enrolment. Ultrasonography of each patient was done for confirmation of pregnancy and correlation of gestational age.</p><p><strong>Results:  </strong>Among 138 pregnant women, subclinical hypothyroidism was detected in 10 (7.2%) patients and subclinical hyperthyroidism was detected in 3 (2.2%) patients. Mean difference of the investigation findings were not statistically significant among primi and multi gravida. TPO-Ab and TG-Ab difference were statistically significant between two age groups.</p><p><strong>Conclusion: </strong>Subclinical thyroid disorders are fairly high among pregnant women. Correct diagnosis in early pregnancy and prompt treatment will bring an excellent prognosis for both mother and offspring.</p><p>Bangladesh J. Nuclear Med. 19(2): 98-102, July 2016</p>

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