scholarly journals Fetal Echocardiography:Short Term Profile from Shahid Gangalal National Heart Centre, Kathmandu, Nepal

2016 ◽  
Vol 13 (1) ◽  
pp. 9-12
Author(s):  
Sudhir Regmi ◽  
Deewakar Sharma
Keyword(s):  
Pregnant Women ◽  
Congenital Heart ◽  
Fetal Echocardiography ◽  
Tertiary Care ◽  
Outcome Data ◽  
Cross Sectional ◽  
Vitro Fertilization ◽  
History Of ◽  
Sectional Analysis

Background and Aims: Fetal echocardiography is helpful in early detection of Congenital Heart Disease. Our study was conducted to evaluate the most common indications of referral and outcome in a tertiary-care fetal echocardiography practice.Methods: A Cross-sectional analysis of all pregnant women referred by obstetricians to cardiology unit for fetal echocardiography over a 1-year period (July 2014 and July 2015) was performed. The primary indications for referral for fetal echocardiography were obtained from the obstetric referral forms. Outcome data were extracted from performa containing client’s demographic, physical examination and the fetal echocardiograhic data. Postnatal Echocardiography was advised to all cases having positive echocardiographic finding.Results: A series of 251 fetal cardiac studies were reviewed. Average gestational age was 25.6 weeks (range, 18 to 38 weeks). Thirty-eight (15.1%) pregnant women had abnormal fetal cardiac findings. The most common referral for fetal cardiac scan was related to maternal indications (48.6%). Other indications were abnormal prenatal fetal findings in ultrasonography (23.1%), family history of CHD (12%), general screening (15.5%), and follow up of IVF (In-vitro fertilization) (0.8%). The highest yield of significant abnormal findings was there among patients referred with abnormal prenatal fetal finding in ultrasonography (47%).Conclusion: Majority of referral were for abnormal prenatal ultrasonographic findings. So, fetal Echocardiography is an important part of overall management of the pregnancy at risk for producing an infant with congenital heart disease.Nepalese Heart Journal 2016; 13(1): 9-12

scholarly journals Abnormal Fetal Echocardiography in Diabetic Pregnant Women at a Tertiary Care Hospital: A Descriptive Cross-sectional Study

2020 ◽  
Vol 58 (227) ◽  
Author(s):  
Jyotshna Sharma ◽  
Sanjeeb Tiwari
Keyword(s):  
Gestational Diabetes ◽  
Pregnant Women ◽  
Tertiary Care Hospital ◽  
Fetal Echocardiography ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
Institutional Review

Introduction: The sedentary lifestyle of women and change in their food habits has a significantrole in developing diabetes in pregnancies. This leads to an increased chance of fetal cardiacabnormality born by a mother with gestational diabetes and pre-existing diabetes. The objectiveof the study is to find out the prevalence of abnormal fetal echocardiography in gestational andpre-existing diabetic pregnant women at a tertiary care hospital. Methods: A descriptive cross-sectional study was conducted among 104 diabetic pregnantwomen in a tertiary care hospital from April 15, 2017, to April 14, 2018. Ethical approvalwas obtained from the institutional review committee. The convenient sampling method wasused. The patients who were diagnosed as gestational diabetes and diabetic before pregnancywere included in the study. Fetal echocardiography was mainly done at a gestational age of22-32 weeks depending upon the time of diagnosis of gestational diabetes and for pre-diabeticwomen, fetal echocardiography was done at 24-26 weeks of gestation. Statistical analysis wasdone using the Statistical Package of the Social Sciences version 20. Results: Among 104 patients, 16 (15.38%) patients had abnormal fetal echocardiography.Eighty-three (79.81%) were gestational diabetics, 21 (20.19%) were pre-existing diabeticwomen. Among 83 gestational diabetes, 7 (8.4%) had abnormal echo finding and among 21pre-existing diabetics, 9 (42.8%) had abnormal echo finding. Conclusions: There was an increased chance of fetal cardiac malformation in gestational diabeticand pre-existing diabetics diabetic especially in an uncontrolled glycemic state. And, if theywere diagnosed prenatally, clinical outcomes for both mother and fetus would have been better.

Multidimensional Psychological Stress During Pregnancies in Women Who Conceived via In Vitro Fertilization

2017 ◽  
Vol 31 (3) ◽  
pp. 295-312 ◽  
Author(s):  
Eleanor L. Stevenson ◽  
Susan Silva
Keyword(s):  
In Vitro Fertilization ◽  
Perceived Stress ◽  
White Women ◽  
Self Report ◽  
Cross Sectional ◽  
Vitro Fertilization ◽  
History Of ◽  
Cross Sectional Design ◽  
Distress Scale

Purpose: To explore relationships among the 3 psychological dimensions of stress, stimulus/environmental, perceptual, and emotional response, and then to develop a multidimensional composite measure of overall stress, and to determine demographic and clinical characteristics associated with stress in women who became pregnant via in vitro fertilization (IVF). Methods: Cross-sectional design using self-report questionnaires during the second trimester. Multidimensional stress was assessed with the Prenatal Life Events Scale, Life Event Distress Scale, Perceived Stress Scale, State-Trait Anxiety Index-State, and the Pregnancy-Related Anxiety Measure. Results: Participants (n = 144), aged 25–40 years, were enrolled June 2010–August 2011 from a private fertility clinic. Exploratory principal factor analysis was used to develop an overall stress score from the stress measures. Multiple stepwise regression analyses were conducted to determine characteristics related to the stress measures. White race tended to be associated with lower stress scores (p = .079). White participants also had lower perceived stress (p = .007), and those with a history of miscarriage had higher pregnancy-related anxiety (p = .035). Conclusions: White women had lower perceived stress. History of one or more miscarriage was associated with higher pregnancy-related anxiety. Additional research examining multidimensional stress is needed across the pregnancy trimesters as well as comparisons to women who conceived without IVF both in United States and internationally.

scholarly journals Indications of Preterm Caesarean Section: Experience of 100 Cases at a Tertiary Care Hospital in Bangladesh

2021 ◽  
Vol 8 (1) ◽  
pp. 49-53
Author(s):  
Rebeka Khanam ◽  
Fatema Mahbooba Akter ◽  
Rabeya Parvin ◽  
Lutfunnahar Shampa
Keyword(s):  
Caesarean Section ◽  
Pregnant Women ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Age Group ◽  
Premature Rupture ◽  
College Hospital ◽  
Cross Sectional ◽  
History Of

Background: Preterm caesarean section is performed for different indication among the pregnant women. Objective: The purpose of the present study was to find out the indications of preterm caesarean section among pregnant women. Methodology: This cross sectional study was conducted in the Department of Obstetric & Gynaecology at Shaheed Ziaur Rahman Medical College Hospital, Bogra, Bangladesh from January 2007 to December 2007 for a period of one year. Women with the gestational age between 32 to 36 completed weeks who were selected for delivery by Caesarean section were selected as study population. All the women of study were assessed on the basis of detailed history, clinical examination, gestational period, history of premature rupture of membranes, any vaginal bleeding and fetal condition. Result: A total number of 100 pregnant women were recruited for this study. In this study most of the pregnant women were in the age group of15 to 20 years which was 40(40.0%) cases followed by the age group of 21 to 25 years which were 20(20.0%) cases. About 43(43.0%) cases were complicated with pregnancy induced hypertension. Almost all of them had indication for immediate caesarean section. Among the group incidence of eclampsia was high which was in 23(23.0%) cases; however, preeclampsia was found in 20(20.0%) cases. Ante partum haemorrhage was reported in 10(10.0%) cases. Pregnant women with premature rupture of membrane (PROM) was found in 14(14.0%) cases; furthermore, PROM with Chorioamnionitis was detected in 5(5.0%) cases. Preterm labour with history of previous caesarean section was given by 5(5.0%) women. Conclusion: In conclusion eclampsia and preeclampsia are the most common indication for preterm caesarean section followed by premature rupture of membrane. Journal of Current and Advance Medical Research, January 2021;8(1):44-48

Is the Rate of Congenital Heart Defects Detected by Fetal Echocardiography Among Pregnancies Conceived by In Vitro Fertilization Really Increased?

2010 ◽  
Vol 29 (6) ◽  
pp. 917-922 ◽  
Author(s):  
Mert Ozan Bahtiyar ◽  
Katherine Campbell ◽  
Antonette T. Dulay ◽  
Olivera Kontic-Vucinic ◽  
Bevin P. Weeks ◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Fetal Echocardiography ◽  
Heart Defects ◽  
Vitro Fertilization

scholarly journals Impact of the Vaginal and Endometrial Microbiome Pattern on Assisted Reproduction Outcomes

2021 ◽  
Vol 10 (18) ◽  
pp. 4063
Author(s):  
María del Carmen Diaz-Martínez ◽  
Andrea Bernabeu ◽  
Belén Lledó ◽  
Concepción Carratalá-Munuera ◽  
Jose A. Quesada ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Relative Abundance ◽  
Diversity Index ◽  
Alpha Diversity ◽  
Vitro Fertilization ◽  
Alpha And Beta Diversity ◽  
History Of ◽  
Health And Disease ◽  
Lactobacillus Spp

Uterine microbiota may be involved in reproductive health and disease. This study aims to describe and compare the vaginal and endometrial microbiome patterns between women who became pregnant and women who did not after in vitro fertilization. We also compared the vaginal and endometrial microbiome patterns between women with and without a history of repeated implantation failures (RIF). This pilot prospective cohort study included 48 women presenting to the fertility clinic for IVF from May 2017 to May 2019. Women who achieved clinical pregnancy presented a greater relative abundance of Lactobacillus spp. in their vaginal samples than those who did not (97.69% versus 94.63%; p = 0.027. The alpha and beta diversity of vaginal and endometrial samples were not statistically different between pregnant and non-pregnant women. The Faith alpha diversity index in vaginal samples was lower in women with RIF than those without RIF (p = 0.027). The alpha diversity of the endometrial microbiome was significantly higher in women without RIF (p = 0.021). There were no significant differences in the vaginal and endometrial microbiomes between pregnant and non-pregnant women. The relative abundance of the genera in women with RIF was different from those without RIF. Statistically significant differences in the endometrial microbiome were found between women with and without RIF.

EVALUATION OF HORMONAL FUNCTION IN WOMEN WITH CERVICAL INSUFFICIENCY AND INFERTILITY IN THE HISTORY

2021 ◽  
Vol 74 (10) ◽  
pp. 2412-2416
Author(s):  
Oksana M. Perkhulyn ◽  
Lyudmyla V. Pakharenko ◽  
Vladyslav S. Sukhin ◽  
Oleksiy V. Saltovskiy ◽  
Viktoriia M. Kovalchuk ◽  
...  
Keyword(s):  
Blood Serum ◽  
Pregnant Women ◽  
Hormonal Treatment ◽  
Placental Lactogen ◽  
Cervical Insufficiency ◽  
Vitro Fertilization ◽  
Healthy Women ◽  
History Of ◽  
Anovulatory Infertility

The aim: To assess the levels of hormones in women with cervical insufficiency and infertility in the history in the II trimester of gestation. Materials and methods: 120 pregnant women with cervical insufficiency and anovulatory infertility in the history were examined in the II trimester of gestation: in the I group (60 persons) pregnancy occurred after hormonal treatment of infertility, in the II group (60 individuals) – after in vitro fertilization. 30 pregnant women without cervical insufficiency and a history of infertility were controls. The levels of estradiol, progesterone, placental lactogen, prolactin and cortisol were determined in the blood serum. Results: The concentration of maternal progesterone was lower in the persons in the I group on 12.36 %, in the II group – on the 15.37 % (p=0.03) compared to the healthy women. Cortisol and prolactin amounts were statistically higher in I and II groups (p<0.001) than in controls. While the levels of estradiol and placental lactogen were slightly less in the subjects with cervical insufficiency and a history of anovulatory infertility compared to the healthy women. Conclusions: In pregnant women with cervical insufficiency and a history of anovulatory infertility in the II trimester of gestation there are decrease progesterone level and high prolactin and cortisol concentrations in blood serum. The changes in estradiol and placental lactogen amounts are not significant compared to healthy women.

scholarly journals Sirtuin 1 Levels in Recurrent Implantation Failure

2017 ◽  
Vol 39 (10) ◽  
pp. 541-544 ◽  
Author(s):  
Yaprak Engin-Ustun ◽  
A. Ozgu-Erdinc ◽  
Emel Kiyak Caglayan ◽  
Cavidan Gulerman ◽  
Esma Sarikaya ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Statistical Significance ◽  
Cross Sectional Study ◽  
Sirtuin 1 ◽  
Implantation Failure ◽  
Recurrent Implantation Failure ◽  
Cross Sectional ◽  
Vitro Fertilization ◽  
Number Of Patients

AbstractSirtuin 1 has an important role in cellular processes, including apoptosis and cellular stress. The purpose of this study was to assess serum sirtuin 1 levels in women with recurrent implantation failure (RIF). In this cross-sectional study, we included 28 women with RIF, 29 healthy women who had conceived by in vitro fertilization (IVF), and 30 women with a 1-cycle failure of IVF as controls. Human serum nicotinamide adenine dinucleotide (NAD)-dependent deacetylase sirtuin-1 (SIRT1/SIRT2L1) levels were detected using a commercial colorimetric kit. Recurrent implantation failure patients have higher sirtuin 1 levels than non-pregnant women and healthy pregnant women, but this difference did not reach statistical significance due to the low number of patients in our study. These higher sirtuin 1 levels may result from the inflammation imbalance of RIF patients. The only statistically significant correlation found was between age and sirtuin (r = 0.277, p = 0.009).

scholarly journals Analysis of factors associated with ovarian reserve in a group of poor responders to in vitro fertilization: A cross-sectional study

2020 ◽  
Author(s):  
Budi Wiweko ◽  
Quamila Fahrizani Afdi ◽  
Achmad Kemal Harzif ◽  
Gita Pratama ◽  
Kanadi Sumapradja ◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Ovarian Reserve ◽  
Poor Responder ◽  
Cross Sectional Study ◽  
Poor Responders ◽  
Cross Sectional ◽  
Vitro Fertilization ◽  
The Poor ◽  
History Of

Background: Poor ovarian reserve and a high rate of pregnancy failure associated with low quality and quantity of oocytes are observed in poor responders to in vitro fertilization. Objective: To assess the effect of age, body mass index (BMI), endometriosis, and history of ovarian surgery on ovarian reserve in a group of poor responders. Materials and Methods: In this cross-sectional study 749 women who referred to Yasmin Clinic of Dr Cipto Mangunkusumo National General Hospital from January 2013 to June 2017 were enrolled. Two definitions of poor responders and Poseidon criteria and consecutive sampling techniques were used. Participants were divided into good and poor responder groups based on the ovarian reserve test; participant with oocyte ≤ 3 was classified as a poor responder. Based on this, 188 participants with nine (4-47) oocytes were included in the poor responder group. While good responder comprised of two (0-3) oocytes. Results: Age and anti-Mullerian hormone level (AMH) were significantly associated with ovarian reserve in the poor-responder group (p < 0.001). However, in multivariate analyses, age was the only significant predictor of ovarian response in the poor responder group (p = 0.004). While endometriosis was the significant predictor of Poseidon groups 1 and 4, surgical history was the significant predictor of Poseidon groups 2 and 3. Meanwhile, an increase in BMI decreased the risk of classification under Poseidon group 3. Conclusion: Age, AMH, BMI, endometriosis, and history of ovarian surgery affected the risk of classification of the Poseidon group. Key words: Ovarian reserve, Poseidon, In vitro fertilization.

scholarly journals The Effect of Stress, Anxiety and Depression on In Vitro Fertilization Outcome in Kazakhstani Public Clinical Setting: A Cross-Sectional Study

2021 ◽  
Vol 10 (5) ◽  
pp. 937
Author(s):  
Gauri Bapayeva ◽  
Gulzhanat Aimagambetova ◽  
Alpamys Issanov ◽  
Sanja Terzic ◽  
Talshyn Ukybassova ◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Depressed Mood ◽  
Depression Scale ◽  
Anxiety Scale ◽  
Clinical Depression ◽  
Cross Sectional ◽  
Vitro Fertilization ◽  
Scale Scores ◽  
The Impact

Although it is clear that infertility leads to heightened stress for patients, the impact of depressed mood and anxiety on treatment outcome is inconsistently reported. The aim of this study was to evaluate the effect of stress, depression and anxiety on in vitro fertilization (IVF) outcomes in Kazakhstani public assisted reproductive technology (ART) clinics. The prospective cohort study was performed between June 2019 and September 2020 using questionnaires to assess psychological stress, depressed mood and anxiety in women referred to IVF clinics in two public clinical centers in Kazakhstan, Nur-Sultan and Aktobe. Our study sample comprised 142 women with the average age of 33.9 ± 4.9 years, and infertility duration 6.0 ± 3.5 years. More than half of respondents had Center for Epidemiological Studies Depression Scale (CES-D) scores higher than 16, indicating their risk of developing clinical depression. Ninety-one percent of women from Aktobe city were at risk for clinical depression (p < 0.001). Aktobe city respondents had higher stress subscale scores and anxiety scale scores (p < 0.001) than Nur-Sultan respondents. Statistical analysis showed that IVF outcome was not significantly associated with depression and stress, while the higher anxiety scale scores were negatively associated with clinical pregnancy after IVF.

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