scholarly journals Incidence Trend of Breast Cancer and its Risk Factors in Women of Eastern Mediterranean Region Countries between 1998 and 2018: A Systematic Review and Meta-Analysis

2019 ◽  
Author(s):  
Razieh Zahedi ◽  
Hossein Molavi Vardanjani ◽  
Mohammad Reza Baneshi ◽  
Ali Akbar Haghdoost ◽  
Reza Malekpour Afshar ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Systematic Review ◽  
Meta Analysis ◽  
Random Effect ◽  
Eastern Mediterranean Region ◽  
Quality Data ◽  
Current Status ◽  
Quality Of Data ◽  
Incidence Trend

Abstract Abstract Background This study was conducted to provide evidence on the current status of breast cancer (BC) and its incidence trend in EMR during 1998-2018. Also, this study aimed to investigate the association between the incidence of BC and HDI and some factors related to this index, including total fertility rate (TFR), and obesity, using a meta-analysis. Method Data on incidence of BC were collected from various sources, including PubMed, Embase, Web of Science, and WHO, from 1998 to 2018 using systematic review and meta-analysis. Pooled ASR (age standardized rate) was calculated based on study duration and quality of data using a subgroup analysis and random effect meta-analysis. Results A total of 76 studies (499 data points) were analyzed. Pooled ASR of BC for EMR was 39.8 per 100 000 person-year (95% confidence interval [CI], 36.01, 43.9) during 2011-2018. ASR of BC had an upward trend in EMR from 2005 to 2018. However, the increasing trend was found to be slightly different in various regions based on quality of data. Moreover, pooled ASR had a significant association with Human Development Index (HDI) [-6.6 (95% CI, -8.9, -4.3)] and obesity [0.1 (95% CI, 0.07, 0.1)]. Conclusion Pooled ASR of BC in EMR was lower than the global average. Also, the ASR value and its incremental trend have been higher in countries with low-quality data than in other countries of this region in recent years. Data quality or physiological factors, such as increase in obesity rates, could be the reasons for this incremental trend.

scholarly journals Incidence Trend of Breast Cancer in Women of Eastern Mediterranean Region countries from 1998 to 2019: A Systematic Review and Meta-Analysis

2019 ◽  
Author(s):  
Razieh Zahedi ◽  
Hossein Molavi Vardanjani ◽  
Mohammad Reza Baneshi ◽  
Ali Akbar Haghdoost ◽  
Reza Malekpour Afshar ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Systematic Review ◽  
Human Development ◽  
Human Development Index ◽  
Mediterranean Region ◽  
Eastern Mediterranean ◽  
Meta Analysis ◽  
Eastern Mediterranean Region ◽  
Quality Of Data

Abstract Background This study was conducted to provide evidence on the current status of breast cancer and its incidence trend in Eastern Mediterranean Region during 1998-2019. Also, this study aimed to investigate the association between the incidence of breast cancer and Human Development Index and some factors related to this index, including total fertility rate, and obesity, using a meta-analysis. Method Data on incidence of breast cancer were collected from various sources, including PubMed, Embase, Web of Science, and WHO, from 1998 to 2019 using systematic review and meta-analysis. Pooled age standardized rate was calculated based on study duration and quality of data using a subgroup analysis and random effect meta-analysis. Results A total of 80 studies (545 data points) were analyzed. Pooled age standardized rate of breast cancer for Eastern Mediterranean Region was 37.1 per 100 000 person-year (95% confidence interval [CI], 34.5, 39.8) during 2011-2019. age standardized rate of breast cancer had an upward trend in Eastern Mediterranean Region from 2005 to 2019. However, the increasing trend was found to be slightly different in various regions based on quality of data. Moreover, pooled age standardized rate had a significant association with Human Development Index [-89.2 (95% CI, -119.8, -58.7)] and obesity [1.2 (95% CI, 0.9, 1.5)]. Conclusion Pooled age standardized rate of breast cancer in Eastern Mediterranean Region was lower than the global average. Also, the age standardized rate value and its incremental trend have been higher in countries with high-quality data than in other countries of this region in recent years. Data quality or physiological factors, such as increase in obesity rates, could be the reasons for this incremental trend.

scholarly journals Incidence Trend of Breast Cancer in Women of Eastern Mediterranean Region countries from 1998 to 2019: A Systematic Review and Meta-Analysis

2020 ◽  
Author(s):  
Razieh Zahedi ◽  
Hossein Molavi Vardanjani ◽  
Mohammad Reza Baneshi ◽  
Ali Akbar Haghdoost ◽  
Reza Malekpour Afshar ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Systematic Review ◽  
Human Development ◽  
Human Development Index ◽  
Mediterranean Region ◽  
Eastern Mediterranean ◽  
Meta Analysis ◽  
Eastern Mediterranean Region ◽  
Quality Of Data

Abstract Background This study was conducted to provide evidence on the current status of breast cancer and its incidence trend in Eastern Mediterranean Region during 1998-2019. Also, this study aimed to investigate the association between the incidence of breast cancer and Human Development Index and some factors related to this index, including total fertility rate, and obesity, using a meta-analysis. Method Data on incidence of breast cancer were collected from various sources, including PubMed, Embase, Web of Science, and WHO, from 1998 to 2019 using systematic review and meta-analysis. Pooled age standardized rate was calculated based on study duration and quality of data using a subgroup analysis and random effect meta-analysis. Results A total of 80 studies (545 data points) were analyzed. Pooled age standardized rate of breast cancer for Eastern Mediterranean Region was 37.1 per 100 000 person-year (95% confidence interval [CI], 34.5, 39.8) during 2011-2019. age standardized rate of breast cancer had an upward trend in Eastern Mediterranean Region from 2005 to 2019. However, the increasing trend was found to be slightly different in various regions based on quality of data. Moreover, pooled age standardized rate had a significant association with Human Development Index [-89.2 (95% CI, -119.8, -58.7)] and obesity [1.2 (95% CI, 0.9, 1.5)]. Conclusion Pooled age standardized rate of breast cancer in Eastern Mediterranean Region was lower than the global average. Also, the age standardized rate value and its incremental trend have been higher in countries with high-quality data than in other countries of this region in recent years. Data quality or physiological factors, such as increase in obesity rates, could be the reasons for this incremental trend. Key words Breast cancer, meta-analysis, Eastern Mediterranean region, Incidence

scholarly journals Incidence trend of breast Cancer in women of eastern Mediterranean region countries from 1998 to 2019: A systematic review and meta-analysis

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Razieh Zahedi ◽  
Hossein Molavi Vardanjani ◽  
Mohammad Reza Baneshi ◽  
Ali Akbar Haghdoost ◽  
Reza Malekpour Afshar ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Systematic Review ◽  
Mediterranean Region ◽  
Eastern Mediterranean ◽  
Meta Analysis ◽  
Eastern Mediterranean Region ◽  
Incidence Trend

scholarly journals Incidence Trend of Breast Cancer and its Risk Factors in Women of Eastern Mediterranean Region Countries between 1998 and 2018: A Systematic Review and Meta-Analysis

2019 ◽  
Author(s):  
Razieh Zahedi ◽  
Hossein Molavi Vardanjani ◽  
Mohammad Reza Baneshi ◽  
Ali Akbar Haghdoost ◽  
Reza Malekpour Afshar ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Systematic Review ◽  
Data Quality ◽  
Mediterranean Region ◽  
Eastern Mediterranean ◽  
Meta Analysis ◽  
Eastern Mediterranean Region ◽  
Quality Data ◽  
Analysis Method

Abstract Background This study was conducted to determine the current Age Standardized Rate (ASR) of breast cancer and its trend from 1998 to 2018, and relational factors of countries’ development as risk factors in breast cancer occurrence in Eastern Mediterranean Region (EMR). Methods Using systematic review and meta-analysis method, data on incidence of breast cancer was collected from various sources including Pubmed, Embase, Web of Science, WHO from 1998 to 2018. Pooled ASR was calculated using subgroup analysis according to period of study and quality of data, by applying random effect meta-analysis method. Results 499 data points (76 studies) were analyzed. Pooled ASR of breast cancer for EMR during 2011-2018 was 39.8 per 100,000 person-years (95% confidence interval [CI], 36.01, 43.9). ASR of Breast cancer had an upward trend in EMR from 2005 to 2018; however, the increasing pattern had been somewhat different in various regions based on data quality groups 1998-2018. Pooled ASR had a significant association with Human Development Index [-6.6 (95%CI, -8.9, -4.3)] and obesity [0.1 (95% CI, 0.07, 0.1)]. Conclusion Pooled ASR of breast cancer in EMR is lower than the global average. The ASR value and incremental trend in low-quality data group is higher than others in recent years. The possible reasons for the incremental trend are data quality or physiological ones such as increasing obesity.

Mindfulness- and Acceptance-Based Interventions for Stroke Survivors: A Systematic Review and Meta-Analysis

2021 ◽  
pp. 003435522110432
Author(s):  
Areum Han
Keyword(s):  
Systematic Review ◽  
Depressive Symptoms ◽  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
Mental Fatigue ◽  
Stroke Survivors ◽  
Positive Effects ◽  
Meta Analyses

Objective: Mindfulness- and acceptance-based intervention (MABI) is an emerging evidenced-based practice, but no systematic review incorporating meta-analyses for MABIs in stroke survivors has been conducted. The objective of this systematic review was to measure the effectiveness of MABIs on outcomes in people with stroke. Method: Three electronic databases, including PubMed, CINAHL, and PsycINFO, were searched to identify relevant studies published in peer-reviewed journals. The methodological quality of the included studies was assessed. Data were extracted and combined in a meta-analysis with a random-effect model to compute the size of the intervention effect. Results: A total of 11 studies met the eligibility criteria. Meta-analyses found a small-to-moderate effect of MABIs on depressive symptoms (standardized mean difference [SMD] = 0.39, 95% confidence interval [CI] = [0.12, 0.66]) and a large effect on mental fatigue (SMD = 1.22, 95% CI = [0.57, 1.87]). No statistically significant effect of MABIs on anxiety, quality of life, and mindfulness was found, but there was a trend in favor of MABIs overall. Conclusions: This meta-analysis found positive effects of MABIs on depressive symptoms and mental fatigue in stroke survivors, but future high-quality studies are needed to guarantee treatment effects of MABIs on varied outcomes in stroke survivors.

Quality of life of children treated for unilateral hearing loss: a systematic review and meta-analysis

2021 ◽  
pp. archdischild-2020-320389
Author(s):  
Sarah Nicolas ◽  
Yohan Gallois ◽  
Marie-Noëlle Calmels ◽  
Olivier Deguine ◽  
Bernard Fraysse ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Hearing Loss ◽  
Meta Analysis ◽  
Random Effect ◽  
Risk Of Bias ◽  
Primary Study ◽  
Unilateral Hearing Loss ◽  
Design Selection

ObjectiveTo evaluate the treatments’ consequences for unilateral hearing loss in children.DesignSystematic review and meta-analysis (CRD42018109417). The MEDLINE, CENTRAL, ISRCTN and ClinicalTrials databases were searched between September 2018 and May 2019. Articles were screened and data were collected independently by two authors following the Cochrane and Preferred Reporting Items for Systematic review and Meta-Analysis guidelines. The risk of bias was evaluated using the Cochrane tool, the Newcastle-Ottawa Scale, the National Institute of Health, USA tool and considering the risk of confounding. In the studies with the lowest risk of bias, a meta-analysis was conducted.InterventionsValidated hearing rehabilitation devices.Patients6–15 years old children with moderate to profound unilateral hearing loss.Main outcome measuresThe primary study outcome was children’s quality of life. Academic performances were studied as an additional outcome.Results731 unique articles were identified from the primary search. Of these, 18 articles met the Population, Intervention, Control, Outcomes and Study design selection criteria. In the eight studies with the lowest risk of bias, two meta-analysis were conducted. There was not enough data on academic results to conduct a meta-analysis. In 73 children included in a fixed effect meta-analysis (two studies), no effect of treatment could be shown (g=−0.20, p=0.39). In 61 children included in a random-effect meta-analysis (six studies), a strong positive effect of hearing treatment on quality of life was demonstrated (g=1.32, p<0.05).ConclusionsThe treatment of unilateral hearing loss seems to improve children’s quality of life. Further research is needed to identify the most effective treatment and its corresponding indications.

scholarly journals Systematic Review with Meta-Analysis: Endoscopic and Surgical Resection for Ampullary Lesions

2020 ◽  
Vol 9 (11) ◽  
pp. 3622
Author(s):  
Christian Heise ◽  
Einas Abou Ali ◽  
Dirk Hasenclever ◽  
Francesco Auriemma ◽  
Aiste Gulla ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Significant Risk ◽  
Significant Heterogeneity ◽  
Incomplete Resection ◽  
Quality Of Data ◽  
Surgical Interventions ◽  
Random Effects Models ◽  
Fixed And Random Effects

Ampullary lesions (ALs) can be treated by endoscopic (EA) or surgical ampullectomy (SA) or pancreaticoduodenectomy (PD). However, EA carries significant risk of incomplete resection while surgical interventions can lead to substantial morbidity. We performed a systematic review and meta-analysis for R0, adverse-events (AEs) and recurrence between EA, SA and PD. Electronic databases were searched from 1990 to 2018. Outcomes were calculated as pooled means using fixed and random-effects models and the Freeman-Tukey-Double-Arcsine-Proportion-model. We identified 59 independent studies. The pooled R0 rate was 76.6% (71.8–81.4%, I2 = 91.38%) for EA, 96.4% (93.6–99.2%, I2 = 37.8%) for SA and 98.9% (98.0–99.7%, I2 = 0%) for PD. AEs were 24.7% (19.8–29.6%, I2 = 86.4%), 28.3% (19.0–37.7%, I2 = 76.8%) and 44.7% (37.9–51.4%, I2 = 0%), respectively. Recurrences were registered in 13.0% (10.2–15.6%, I2 = 91.3%), 9.4% (4.8–14%, I2 = 57.3%) and 14.2% (9.5–18.9%, I2 = 0%). Differences between proportions were significant in R0 for EA compared to SA (p = 0.007) and PD (p = 0.022). AEs were statistically different only between EA and PD (p = 0.049) and recurrence showed no significance for EA/SA or EA/PD. Our data indicate an increased rate of complete resection in surgical interventions accompanied with a higher risk of complications. However, studies showed various sources of bias, limited quality of data and a significant heterogeneity, particularly in EA studies.

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