scholarly journals Premature Mortality of Gastrointestinal Cancer in Iran: Trends and Projections for 2001–2030

2020 ◽  
Author(s):  
Fatemeh Khosravi Shadmani ◽  
Farshad Farzadfar ◽  
Moein Yoosefi ◽  
Kamyar Mansori ◽  
Reza Khosravi Shadman ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Premature Mortality ◽  
Population Data ◽  
Mortality Trends ◽  
Control Plan ◽  
Temporal Correlations ◽  
Liver Cancers ◽  
Colon And Rectum ◽  
Gi Cancers ◽  
Spatio Temporal

Abstract Background: The aim of this study was to determine the trend and projection of premature mortality from gastrointestinal cancers (GI) at national and subnational levels in Iran.Methods: According to the data gathered through Iranian Death Registry System (DRS) and population data from census, mortality rate was calculated among 30-70 age group. The trends of premature mortality of esophageal, colon and rectum, gallbladder, pancreases, stomach, and liver cancers were estimated and projected at the national and subnational levels from 2001 to 2030. Spatio-temporal model was used to project spatial and temporal correlations. Results: The mortality rate of GI cancers in males was higher than females, indicating 6.1, 3.9 and 3.9 percent per 100000 in 2001, 2015 and 2030 respectively among males; whereas, the corresponding values for females were 3.8, 3.1 and 3.7 per 100000. The mortality rate of GI cancers had been decreasing by 2015 but it will remain stable by 2030 in males; however, the rate will be increasing in females. Also, there was a considerable variation in the mortality trends of different cancers. Pancreatic, gallbladder, and liver cancers were shown to have an increasing trend while a dropped was observed in the mortality of stomach, colon and rectum, and esophageal cancers. Conclusion: The difference in the patterns of GI cancers and their trends around the country showed that a more comprehensive control plan is needed that includes the predicted variations.

scholarly journals Premature Mortality of Gastrointestinal Cancer in Iran: Trends and Projections for 2001–2030

2019 ◽  
Author(s):  
Fatemeh Khosravi Shadmani ◽  
Farshad Farzadfar ◽  
Moein Yoosefi ◽  
Kamyar Mansori ◽  
Reza Khosravi Shadman ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Premature Mortality ◽  
Population Data ◽  
Mortality Trends ◽  
Control Plan ◽  
Temporal Correlations ◽  
Liver Cancers ◽  
Colon And Rectum ◽  
Gi Cancers ◽  
Spatio Temporal

Abstract Background: The aim of this study was to determine the trend and projection of premature mortality from gastrointestinal cancers (GI) at national and subnational levels in Iran. Methods: According to the data gathered through Iranian Death Registry System (DRS) and population data from census, mortality rate was calculated among 30-70 age group. The trends of premature mortality of esophageal, colon and rectum, gallbladder, pancreases, stomach, and liver cancers were estimated and projected at the national and subnational levels from 2001 to 2030. Spatio-temporal model was used to project spatial and temporal correlations. Results: The mortality rate of GI cancers in males was higher than females, indicating 6.1, 3.9 and 3.9 percent per 100000 in 2001, 2015 and 2030 respectively among males; whereas, the corresponding values for females were 3.8, 3.1 and 3.7 per 100000. The mortality rate of GI cancers had been decreasing by 2015 but it will remain stable by 2030 in males; however, the rate will be increasing in females. Also, there was a considerable variation in the mortality trends of different cancers. Pancreatic, gallbladder, and liver cancers were shown to have an increasing trend while a dropped was observed in the mortality of stomach, colon and rectum, and esophageal cancers. Conclusion: The difference in the patterns of GI cancers and their trends around the country showed that a more comprehensive control plan is needed that includes the predicted variations.

scholarly journals Premature Mortality of Gastrointestinal Cancer in Iran: Trends and Projections for 2001–2030

2020 ◽  
Author(s):  
Fatemeh Khosravi Shadmani ◽  
Farshad Farzadfar ◽  
Moein Yoosefi ◽  
Kamyar Mansori ◽  
Reza Khosravi Shadman ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Age Groups ◽  
Premature Mortality ◽  
Mortality Rates ◽  
Mortality Trends ◽  
Control Plan ◽  
Liver Cancers ◽  
Colon And Rectum ◽  
Gi Cancers ◽  
Overall Mortality

Abstract Background: The present study was conducted to determine the trend and projection of premature mortality from gastrointestinal cancers (GI cancers) at national and subnational levels in Iran.Methods: Employing the data obtained from Iranian Death Registry System (DRS) and population data from census, the mortality rates of GI cancers was calculated among 30-70 age groups. The trends of esophageal, colon and rectum, gallbladder, pancreases, stomach, and liver cancer premature mortalities were estimated and projected at the national and subnational levels from 2001 to 2030. Then, Spatio-temporal model was used to project spatial and temporal correlations. Results: The overall mortality rate of GI cancers was higher in males than in females, indicating 6.1, 3.9 and 3.9 percent per 100000 individuals among males in 2001, 2015 and 2030 respectively and 3.8, 3.1 and 3.7 per 100000 individuals among females in the same time-frame. The overall mortality rate of GI cancers in males was decreasing until 2015 and will remain stationary into 2030; however, the rate will be increasing among females in both time-frames. Also, there was a considerable variation in the mortality trends of different cancers. Pancreatic, gallbladder, and liver cancers were shown to have an increasing trend while a drop was observed in the mortality rates of stomach, colon and rectum, and esophageal cancers. Conclusion: Variation of GI cancers patterns and trends around the country indicated that a more comprehensive control plan is needed to include the predicted variations.

scholarly journals Premature Mortality of Gastrointestinal Cancer in Iran: Trends and Projections for 2001–2030

2020 ◽  
Author(s):  
Fatemeh Khosravi Shadmani ◽  
Farshad Farzadfar ◽  
Moein Yoosefi ◽  
Kamyar Mansori ◽  
Reza Khosravi Shadman ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Age Groups ◽  
Premature Mortality ◽  
Mortality Rates ◽  
Mortality Trends ◽  
Control Plan ◽  
Liver Cancers ◽  
Colon And Rectum ◽  
Gi Cancers ◽  
Overall Mortality

Abstract Background: The present study was conducted to determine the trend and projection of premature mortality from gastrointestinal cancers (GI cancers) at national and subnational levels in Iran.Methods: Employing the data obtained from Iranian Death Registry System (DRS) and population data from census, the mortality rates of GI cancers was calculated among 30-70 age groups. The trends of esophageal, colon and rectum, gallbladder, pancreases, stomach, and liver cancer premature mortalities were estimated and projected at the national and subnational levels from 2001 to 2030. Then, Spatio-temporal model was used to project spatial and temporal correlations. Results: The overall mortality rate of GI cancers was higher in males than in females, indicating 6.1, 3.9 and 3.9 percent per 100000 individuals among males in 2001, 2015 and 2030 respectively and 3.8, 3.1 and 3.7 per 100000 individuals among females in the same time-frame. The overall mortality rate of GI cancers in males was decreasing until 2015 and will remain stationary into 2030; however, the rate will be increasing among females in both time-frames. Also, there was a considerable variation in the mortality trends of different cancers. Pancreatic, gallbladder, and liver cancers were shown to have an increasing trend while a drop was observed in the mortality rates of stomach, colon and rectum, and esophageal cancers. Conclusion: Variation of GI cancers patterns and trends around the country indicated that a more comprehensive control plan is needed to include the predicted variations.

scholarly journals ‘Trend in premature mortality from four major NCDs in Nanjing, China, 2007–2018’

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Huafeng Yang ◽  
Yali Fu ◽  
Xin Hong ◽  
Hao Yu ◽  
Weiwei Wang ◽  
...  
Keyword(s):  
Rural Areas ◽  
Urban Areas ◽  
Respiratory Diseases ◽  
Premature Mortality ◽  
Population Data ◽  
Integrated Approach ◽  
Mortality Data ◽  
Relative Reduction ◽  
Mortality Trends ◽  
Chronic Respiratory Diseases

Abstract Background This study aims to analyze the trends of premature mortality caused from four major non-communicable diseases (NCDs), namely cardiovascular disease (CVD), cancer, chronic respiratory diseases, and diabetes in Nanjing between 2007 and 2018 and project the ability to achieve the “Healthy China 2030” reduction target. Methods Mortality data of four major NCDs for the period 2007–2018 were extracted from the Death Information Registration and Management System of Chinese Center for Disease Control and Prevention. Population data for Nanjing were provided by the Nanjing Bureau of Public Security. The premature mortality was calculated using the life table method. Joinpoint regression model was used to estimate the average annual percent changes (AAPC) in mortality trends. Results From 2007 to 2018, the premature mortality from four major NCDs combined in Nanjing decreased from 15.5 to 9.5%, with the AAPC value at − 4.3% (95% CI [− 5.2% to − 3.4%]). Overall, it can potentially achieve the target, with a relative reduction 28.6%. The premature mortality from cancer, CVD, chronic respiratory diseases and diabetes all decreased, with AAPC values at − 4.2, − 5.0%, − 5.9% and − 1.6% respectively. A relative reduction of 40.6 and 41.2% in females and in rural areas, but only 21.0 and 12.8% in males and in urban areas were projected. Conclusion An integrated approach should be taken focusing on the modifiable risk factors across different sectors and disciplines in Nanjing. The prevention and treatment of cancers, diabetes, male and rural areas NCDs should be enhanced.

Trends of Diabetes Mortality in Iran at National and Sub-national levels from 1990 to 2015 and its association with socioeconomic factors

2020 ◽  
Author(s):  
Niloofar Peykari ◽  
Sahar Saeedi Moghaddam ◽  
Nazila Rezaei ◽  
Anita Mansouri ◽  
Shohreh Naderimagham ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Socioeconomic Factors ◽  
National Level ◽  
Gaussian Process Regression ◽  
Mortality Trends ◽  
Registration System ◽  
Diabetes Mortality ◽  
Spatio Temporal ◽  
The Difference ◽  
National Trends

Abstract Background Following global commitments to prevent and control non-communicable diseases, we sought to estimate national and sub-national trends in diabetes mortality in Iran and to assess its association with socioeconomic factors.Methods To assess the correlation between diabetes mortality and socioeconomic factors we used data obtained from the Death Registration System (DRS), the spatio-temporal model and Gaussian Process Regression (GPR) levels and the diabetes mortality trends, which were estimated by sex, age and year at national and sub-national levels from 1990 to 2015.Results Between the years 1990 and 2015, the age-standardized diabetes mortality rate (per 100,000) increased from 3.40 (95% UI: 2.33 to 4.99) to 7.72 (95% UI: 5.51 to 10.78) in males and from 4.66 (95% UI: 3.23 to 6.76) to 10.38 (95% UI: 7.54 to 14.23) in females. In 1990, the difference between the highest age-standardized diabetes mortality rate among males was 3.88 times greater than the lowest (5.97 vs. 1.54) and in 2015 this difference was 3.96 times greater (14.65 vs. 3.70). This provincial difference was higher among females and was 5.13 times greater in 1990 (8.41 vs. 1.64) and 5.04 times greater in 2015 (19.87 vs. 3.94). The rate of diabetes mortality rose with urbanization, yet declined with an increase in wealth and years of schooling as the main socio-economic factors.Conclusion The rising trend of diabetes mortality rate at national level and the sub-national disparities associated with socioeconomic status in Iran warrant the implementation of specific interventions recommended by the ‘25 by 25’ goal.

Investigation of a common gene expression signature in gastrointestinal cancers using systems biology approaches

2017 ◽  
Vol 13 (11) ◽  
pp. 2277-2288 ◽  
Author(s):  
Kaveh Baghaei ◽  
Nazanin Hosseinkhan ◽  
Hamid Asadzadeh Aghdaei ◽  
M. R. Zali
Keyword(s):  
Gene Expression ◽  
Systems Biology ◽  
Mortality Rate ◽  
Gene Expression Signature ◽  
Gastrointestinal Cancers ◽  
Common Gene ◽  
Expression Signature ◽  
Liver Cancers ◽  
Gi Cancers

According to GLOBOCAN 2012, the incidence and the mortality rate of colorectal, stomach and liver cancers are the highest among the total gastrointestinal (GI) cancers.

scholarly journals Stereo-PIV measurements of spatio-temporal turbulence correlations in an axisymmetric jet

2015 ◽  
Vol 778 ◽  
pp. 216-252 ◽  
Author(s):  
C. D. Pokora ◽  
J. J. McGuirk
Keyword(s):  
Fourth Order ◽  
Single Point ◽  
Aerodynamic Noise ◽  
Filter Method ◽  
Frequency Noise ◽  
Turbulent Structures ◽  
Validation Data ◽  
Piv Measurements ◽  
Temporal Correlations ◽  
Spatio Temporal

Stereoscopic three-component particle image velocimetry (3C-PIV) measurements have been made in a turbulent round jet to investigate the spatio-temporal correlations that are the origin of aerodynamic noise. Restricting attention to subsonic, isothermal jets, measurements were taken in a water flow experiment where, for the same Reynolds number and nozzle size, the shortest time scale of the dynamically important turbulent structures is more than an order of magnitude greater that in equivalent airflow experiments, greatly facilitating time-resolved PIV measurements. Results obtained (for a jet nozzle diameter and velocity of 40 mm and $1~\text{m}~\text{s}^{-1}$, giving $\mathit{Re}=4\times 10^{4}$) show that, on the basis of both single-point statistics and two-point quantities (correlation functions, integral length scales) the present incompressible flow data are in excellent agreement with published compressible, subsonic airflow measurements. The 3C-PIV data are first compared to higher-spatial-resolution 2C-PIV data and observed to be in good agreement, although some deterioration in quality for higher-order correlations caused by high-frequency noise in the 3C-PIV data is noted. A filter method to correct for this is proposed, based on proper orthogonal decomposition (POD) of the 3C-PIV data. The corrected data are then used to construct correlation maps at the second- and fourth-order level for all velocity components. The present data are in accordance with existing hot-wire measurements, but provide significantly more detailed information on correlation components than has previously been available. The measured relative magnitudes of various components of the two-point fourth-order turbulence correlation coefficient ($R_{ij,kl}$) – the fundamental building block for free shear flow aerodynamic noise sources – are presented and represent a valuable source of validation data for acoustic source modelling. The relationship between fourth-order and second-order velocity correlations is also examined, based on an assumption of a quasi-Gaussian nearly normal p.d.f. for the velocity fluctuations. The present results indicate that this approximation shows reasonable agreement for the measured relative magnitudes of several correlation components; however, areas of discrepancy are identified, indicating the need for work on alternative models such as the shell turbulence concept of Afsar (Eur. J. Mech. (B/Fluids), vol. 31, 2012, pp. 129–139).

Trends in hospitalization and in-hospital mortality of patients with heart failure in Spain. A population-based study (2003–2015)

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
J.L Bonilla Palomas ◽  
M.P Anguita-Sanchez ◽  
F.J Elola ◽  
J.L Bernal ◽  
C Fernandez-Perez ◽  
...  
Keyword(s):  
Heart Failure ◽  
Mortality Rate ◽  
Hospital Mortality ◽  
National Health System ◽  
Admission Rate ◽  
Population Data ◽  
Principal Diagnosis ◽  
Data Set ◽  
Discharge Rates ◽  
Mortality Ratio

Abstract Background Heart failure (HF) is one of the most pressing current public health concerns. However, in Spain there is a lack of population data. Purpose To investigate trends in HF hospitalization and in-hospital mortality rates. Methods We conducted a retrospective observational study of patients discharged with the principal diagnosis of HF from The National Health System' acute hospitals during 2003–2015. The source of the data was the Minimum Basic Data Set of the Ministry of Health, Consumer and Social Welfare. We analyzed trends in hospital discharge rates for HF (discharge rates were weighted by age and gender) an in-hospital mortality. The risk-standardized in-hospital mortality ratio (RSMR) was defined as the ratio between predicted mortality (which individually considers the performance of the hospital where the patient is attended) and expected mortality (which considers a standard performance according to the average of all hospitals) multiplied by the crude rate of mortality. RSMR was calculated using a risk adjustment multilevel logistic regression models developed by the Medicare and Medicaid Services. Temporal trend during the observed period was modelled using Poisson regression analysis with year as the only independent variable. In this model, the incidence rate ratio (IRR) and their 95% confidence intervals (95% CI) was calculated. Results A total of 1 254 830 episodes of HF were selected. Throughout 2003–2015 the number of hospital discharges with principal diagnosis of HF increased by 61% (IRR: 1.04; CI: 1.03–1.04; p<0.001), meanwhile the crude mortality rate and the mean length of stay (LOS) diminished significantly (IRR: 0.99; CI: 0.98–1; and IRR: 1.04; CI: 0.99–0.99; p<0.001, for both). Discharge rates weighted by age and sex showed a statistically significant increase during the period (IRR: 1.03; CI: 1.03–1.03; p<0.001); however, whereas discharge rates increased significantly in older groups of age (≥75 years old) (IRR: 1–1.02; p<0.001) they diminished in younger groups of age (45–74 years old) (IRR: 0.99; p<0.001 and there was not a significant trend in the discharge rates for the group of 35–44 years old (Figure). The risk-standardized in-hospital mortality ratio did not significantly change throughout 2003–2015 (IRR: 0.997; CI: 0.992–1; p=0.32), however the risk-standardized LOS ratio diminished from 1.07 in 2003 to 0.97 in 2015 (IRR: 0.98: IC: 0.98–0.99; p<0.001). Conclusions From 2003 to 2015, HF admission rate increased significantly in Spain as a consequence of the sustained increase of hospitalization in the population over 75. The crude in-hospital mortality rate diminished significantly for the same period, but the risk-standardized in-hospital mortality ratio did not significantly change. Figure 1 Funding Acknowledgement Type of funding source: None

Sign in / Sign up

Export Citation Format

Share Document