scholarly journals Trends in the incidence of diabetes mellitus: results from the Global Burden of Disease Study 2017 and implications for diabetes mellitus prevention

2020 ◽  
Author(s):  
Jinli Liu ◽  
Zhen-Hu Ren ◽  
Hua Qiang ◽  
Jine Wu ◽  
Mingwang Shen ◽  
...  

Abstract Backgroud: Diabetes mellitus is a common chronic disease and a severe public health issue. The incidence trends for type 1 diabetes (TIDM) and type 2 diabetes (T2DM) have rarely been studied on a global scale. We aimed to determine the temporal and geographical trends of diabetes globally.Methods: Data on diabetes mellitus, including incidence, prevalence from 1990 to 2017 were obtained from the 2017 Global Burden of Disease study. We calculated the estimated annual percentage changes (EAPCs) in age-standardized incidence rate (ASIR) of diabetes mellitus according to sex, region, and disease type.Results: The worldwide incident cases of diabetes mellitus has increased by 102.9% from 11,303,084 cases in 1990 to 22,935,630 cases in 2017 worldwide, while the ASIR increased from 233.58/100,000 persons (95% UI, 218.95–249.37) to 284.56/100,000 persons (95% UI, 262.17–309.71) in this period [EAPC=0.87, 95% confidence interval (CI):0.79–0.96]. The global ASIRs of T1DM and T2DM both demonstrated significant increase during 1990-2017, with EAPCs of 0.34 (95% CI:0.30–0.39) and 0.89 (95% CI:0.80–0.97), respectively. The ASIR trends also varied considerably by regions and countries. The increase in ASIR was greatest in high sociodemographic index regions (EAPC=1.05, 95% CI:0.92–1.17) and lowest in low-SDI regions (EAPC=0.79, 95% CI:0.71–0.88). Conclusions: Both the number of incident cases and ASIR of diabetes mellitus increased significantly during 1990-2017 worldwide, but the temporal trends varied markedly across regions and countries.

2020 ◽  
Author(s):  
Jinli Liu ◽  
Zhen-Hu Ren ◽  
Hua Qiang ◽  
Jine Wu ◽  
Mingwang Shen ◽  
...  

Abstract Backgroud: Diabetes mellitus is a common chronic disease and a severe public health issue. The incidence trends for type 1 diabetes (TIDM) and type 2 diabetes (T2DM) have rarely been studied on a global scale. We aimed to determine the temporal and geographical trends of diabetes globally.Methods: Data on diabetes mellitus, including incidence, prevalence from 1990 to 2017 were obtained from the 2017 Global Burden of Disease study. We calculated the estimated annual percentage changes (EAPCs) in age-standardized incidence rate (ASR) of diabetes mellitus according to sex, region, and disease type.Results: The worldwide incident cases of diabetes mellitus has increased by 102.9% from 11,303,084 cases in 1990 to 22,935,630 cases in 2017 worldwide, while the ASR increased from 233.58/100,000 persons (95% UI, 218.95–249.37) to 284.56/100,000 persons (95% UI, 262.17–309.71) in this period [EAPC=0.87, 95% confidence interval (CI):0.79–0.96]. The global ASRs of T1DM and T2DM both demonstrated significant increase during 1990-2017, with EAPCs of 0.34 (95% CI:0.30–0.39) and 0.89 (95% CI:0.80–0.97), respectively. The ASR trends also varied considerably by regions and countries. The increase in ASR was greatest in high sociodemographic index regions (EAPC=1.05, 95% CI:0.92–1.17) and lowest in low-SDI regions (EAPC=0.79, 95% CI:0.71–0.88).Conclusions: Both the number of incident cases and ASR of diabetes mellitus increased significantly during 1990-2017 worldwide, but the temporal trends varied markedly across regions and countries.


2020 ◽  
Author(s):  
Jinli Liu ◽  
Zhen-Hu Ren ◽  
Hua Qiang ◽  
Jine Wu ◽  
Mingwang Shen ◽  
...  

Abstract Backgroud: Diabetes mellitus is a common chronic disease and a severe public health issue. The incidence trends for type 1 diabetes (TIDM) and type 2 diabetes (T2DM) have rarely been studied on a global scale. We aimed to determine the temporal and geographical trends of diabetes globally.Methods: Data on diabetes mellitus, including incidence, prevalence from 1990 to 2017 were obtained from the 2017 Global Burden of Disease study. We calculated the estimated annual percentage changes (EAPCs) in age-standardized incidence rate (ASIR) of diabetes mellitus according to sex, region, and disease type.Results: The worldwide incident cases of diabetes mellitus has increased by 102.9% from 11,303,084 cases in 1990 to 22,935,630 cases in 2017 worldwide, while the ASIR increased from 233.58/100,000 persons (95% UI, 218.95–249.37) to 284.56/100,000 persons (95% UI, 262.17–309.71) in this period [EAPC=0.87, 95% confidence interval (CI):0.79–0.96]. The global ASIRs of T1DM and T2DM both demonstrated significant increase during 1990-2017, with EAPCs of 0.34 (95% CI:0.30–0.39) and 0.89 (95% CI:0.80–0.97), respectively. The ASIR trends also varied considerably by regions and countries. The increase in ASIR was greatest in high sociodemographic index regions (EAPC=1.05, 95% CI:0.92–1.17) and lowest in low-SDI regions (EAPC=0.79, 95% CI:0.71–0.88).Conclusions: Both the number of incident cases and ASIR of diabetes mellitus increased significantly during 1990-2017 worldwide, but the temporal trends varied markedly across regions and countries.


2020 ◽  
Author(s):  
Jinli Liu ◽  
Zhen-Hu Ren ◽  
Hua Qiang ◽  
Jine Wu ◽  
Mingwang Shen ◽  
...  

Abstract Backgroud: Diabetes mellitus is a common chronic disease and a severe public health issue. The incidence trends for type 1 diabetes (TIDM) and type 2 diabetes (T2DM) have rarely been studied on a global scale. We aimed to determine the temporal and geographical trends of diabetes globally.Methods: Data on diabetes mellitus, including incidence, prevalence from 1990 to 2017 were obtained from the 2017 Global Burden of Disease study. We calculated the estimated annual percentage changes (EAPCs) in age-standardized incidence rate (ASR) of diabetes mellitus according to sex, region, and disease type.Results: The worldwide incident cases of diabetes mellitus has increased by 102.9% from 11,303,084 cases in 1990 to 22,935,630 cases in 2017 worldwide, while the ASR increased from 233.58/100,000 persons (95% UI, 218.95–249.37) to 284.56/100,000 persons (95% UI, 262.17–309.71) in this period [EAPC=0.87, 95% confidence interval (CI):0.79–0.96]. The global ASRs of T1DM and T2DM both demonstrated significant increase during 1990-2017, with EAPCs of 0.34 (95% CI:0.30–0.39) and 0.89 (95% CI:0.80–0.97), respectively. The ASR trends also varied considerably by regions and countries. The increase in ASR was greatest in high sociodemographic index regions (EAPC=1.05, 95% CI:0.92–1.17) and lowest in low-SDI regions (EAPC=0.79, 95% CI:0.71–0.88). Conclusions: Both the number of incident cases and ASR of diabetes mellitus increased significantly during 1990-2017 worldwide, but the temporal trends varied markedly across regions and countries.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Jinli Liu ◽  
Zhen-Hu Ren ◽  
Hua Qiang ◽  
Jine Wu ◽  
Mingwang Shen ◽  
...  

Abstract Backgroud Diabetes mellitus is a common chronic disease and a severe public health issue. The incidence trends for type 1 diabetes (TIDM) and type 2 diabetes (T2DM) have rarely been studied on a global scale. We aimed to determine the temporal and geographical trends of diabetes globally. Methods Data on diabetes mellitus, including incidence, prevalence from 1990 to 2017 were obtained from the 2017 Global Burden of Disease study. We calculated the estimated annual percentage changes (EAPCs) in age-standardized incidence rate (ASIR) of diabetes mellitus according to sex, region, and disease type. Results The worldwide incident cases of diabetes mellitus has increased by 102.9% from 11,303,084 cases in 1990 to 22,935,630 cases in 2017 worldwide, while the ASIR increased from 234 /100,000 persons (95% UI, 219–249) to 285/100,000 persons (95% UI, 262–310) in this period [EAPC = 0.87, 95% confidence interval (CI):0.79–0.96]. The global ASIRs of T1DM and T2DM both demonstrated significant increase during 1990–2017, with EAPCs of 0.34 (95% CI,0.30–0.39) and 0.89 (95% CI,0.80–0.97), respectively. The ASIR trends also varied considerably by regions and countries. The increase in ASIR was greatest in high sociodemographic index regions (EAPC = 1.05, 95% CI:0.92–1.17) and lowest in low-SDI regions (EAPC = 0.79, 95% CI:0.71–0.88). Conclusions Both the number of incident cases and ASIR of diabetes mellitus increased significantly during 1990–2017 worldwide, but the temporal trends varied markedly across regions and countries.


2019 ◽  
Author(s):  
Jinli Liu ◽  
Zhen-Hu Ren ◽  
Hua Qiang ◽  
Jine Wu ◽  
Mingwang Shen ◽  
...  

Abstract Backgroud:Diabetes mellitus is a common chronic disease and a severe public health issue. The incidence trends for type 1 diabetes (TIDM) and type 2 diabetes (T2DM) have rarely been studied on a global scale. We aimed to determine the temporal and geographical trends of diabetes globally. Methods:We collected detailed information on diabetes during 1990-2017 based on the 2017 Global Burden of Disease Study and calculated the estimated annual percentage changes (EAPCs) in age-standardized incidence rate (ASR) of diabetes mellitus according to sex, region, and disease type. Results:The incidence of diabetes mellitus increased by 102.9% worldwide, from 11,303,084 cases in 1990 to 22,935,630 cases in 2017, while the ASR increased from 233.6 per 100,000 person-year (py) to 284.6 per 100,000py [EAPC=0.87, 95% confidence interval (CI):0.79,0.96]. The global ASRs of T1DM and T2DM demonstrated significantly increasing trends during 1990-2017, with EAPC of 0.34(95% CI:0.30,0.39) and 0.89 (95% CI:0.80,0.97), respectively. The incidence trends also varied considerably by regions and countries. The increase in ASR was largest in high-SDI regions (EAPC=1.05, 95% CI:0.92,1.17) and smallest in low-SDI regions (EAPC=0.79, 95% CI:0.71,0.88).The EAPC of diabetes mellitus showed a declining trend in countries with a high human development index (HDI). Conclusions: Diabetes mellitus is a worldwide public health problem. Both the number of cases and ASR of diabetes mellitus increased significantly during 1990-2017 worldwide, but the temporal trends varied markedly across regions and countries.In addition, the ASR of T1DM differed with latitude and the farther away from the equator, the higher the ASR in 2017.


2019 ◽  
Author(s):  
Peng Shi ◽  
Xiaoyue Xing ◽  
Shuhua Xi ◽  
Hongmei Jing ◽  
Jiamei Yuan ◽  
...  

Abstract Pneumoconiosis has the potential to cause progressive and permanent physical disability. And continues to be one of major public health concern across the world. However, our literature searches identified a scarcity of data about global prevalence of pneumoconiosis. Accurate data on the incidence of pneumoconiosis is critical for health resource planning and health policy development. We therefore aimed to determine the pattern of pneumoconiosis incidence and temporal trends. Methods: Annual incident cases and age standardized incidence rates on pneumoconiosis etiology between 1990-2017 were collected from the Global Burden of Disease Study 2017. We calculate the average annual percentage changes of age standardized incidence rates by sex, region, and etiology to determine incidence trends of pneumoconiosis. Results: Globally, the number of pneumoconiosis cases increased 66.0% from 36,186 in 1990 to 60,055 in 2017. The overall age standardized incidence rate decreased by an average 0.6% (95% CI: 0.5%, 0.6%) per year in the same period. The age standardized incidence rate of silicosis, asbestosis, and other pneumoconiosis decreased between 1990 and 2017. The corresponding average annual percentage changes were -0.8%, -0.9%, and -0.5%, respectively. The age standardized incidence rate of asbestosis displayed an increasing trend. At the same time, we also found a significant negative association was found between average annual percentage changes and socio-demographic indexs when the socio-demographic index above 0.7. Conclusions: Pneumoconiosis remains a major occupational health illnesses in the world. Incidence patterns of pneumoconiosis caused by different etiologies were heterogeneous across regions and countries. We observed an unfavorable trend that asbestosis was predominant in countries with a high socio-demographic index, though we have attained great achievements in silicosis and coal workers’ pneumoconiosis prevention. The information in this study suggests that some countries should establish more targeted and specific strategies to forestall the increase in pneumoconiosis.


2020 ◽  
Vol 77 (6) ◽  
pp. 407-414 ◽  
Author(s):  
Peng Shi ◽  
Xiaoyue Xing ◽  
Shuhua Xi ◽  
Hongmei Jing ◽  
Jiamei Yuan ◽  
...  

ObjectivesPneumoconiosis remains a major global occupational health hazard and illness. Accurate data on the incidence of pneumoconiosis are critical for health resource planning and development of health policy.MethodsWe collected data for the period between 1990 and 2017 on the annual incident cases and the age-standardised incidence rates (ASIR) of pneumoconiosis aetiology from the Global Burden of Disease Study 2017. We calculated the average annual percentage changes of ASIR by sex, region and aetiology in order to determine the trends of pneumoconiosis.ResultsGlobally, the number of pneumoconiosis cases increased by a measure of 66.0%, from 36 186 in 1990 to 60 055 in 2017. The overall ASIR decreased by an average of 0.6% per year in the same period. The number of pneumoconiosis cases increased across the five sociodemographic index regions, and there was a decrease in the ASIR from 1990 to 2017. The ASIR of silicosis, coal workers’ pneumoconiosis and other pneumoconiosis decreased. In contrast, measures of the ASIR of asbestosis displayed an increasing trend. Patterns of the incidence of pneumoconiosis caused by different aetiologies were found to have been heterogeneous for analyses across regions and among countries.ConclusionIncidence patterns of pneumoconiosis which were caused by different aetiologies varied considerably across regions and countries of the world. The patterns of incidence and temporal trends should facilitate the establishment of more effective and increasingly targeted methods for prevention of pneumoconiosis and reduce associated disease burden.


2021 ◽  
pp. 1429-1441
Author(s):  
Yuefen Hu ◽  
Qizhao Li ◽  
Ming Hou ◽  
Jun Peng ◽  
Xiaorong Yang ◽  
...  

PURPOSE To map the magnitudes and temporal trends of chronic myeloid leukemia (CML) along with its attributable risk factors, providing the essential foundation for targeted public policies at the national, regional, and global levels. MATERIALS AND METHODS We retrieved annual data on CML burden in 204 countries and regions from the Global Burden of Disease Study 2019 in 1990-2019. The estimated annual percentage change (EAPC) was calculated to quantify the temporal trends of CML burden by region, sex, and age group. RESULTS Globally, the age-standardized incidence rate of CML declined weakly over the past few years (EAPC: −1.04), but the number of incident cases increased by 54.1% to 65.8 × 103 in 2019. By contrast, a dramatic drop in death and disability-adjusted life years (DALYs) rate (EAPCs: −2.55; −2.69) led to a reduction in deaths and DALYs, especially in high-income regions. In 2019, the highest age-standardized death rate was observed in Ethiopia (1.89 per 100,000). The death rate of CML was pronounced among the population age above 70 years. DALYs of CML worldwide were primarily attributable to smoking (12.2%), high body mass index (5.0%), occupational exposure to benzene (0.9%), and occupational exposure to formaldehyde (0.3%) in 2019. CONCLUSION Although the mortality rate of CML has decreased significantly, the management of patients with CML cannot be neglected, especially in elders and developing regions.


Author(s):  
Hairong He ◽  
Qingqing Liu ◽  
Ning Li ◽  
Liyang Guo ◽  
Fengjie Gao ◽  
...  

Abstract Aim Schizophrenia is a serious health problem worldwide. This systematic analysis aims to quantify the burden of schizophrenia at the global, regional and national levels using the Global Burden of Disease Study 2017 (GBD 2017). Methods We collected detailed information on the number of incidence cases, disability-adjusted life years (DALYs) and age-standardised incidence rate (ASIR) and age-standardised rate of DALYs (ASDR) during 1990–2017 from GBD 2017. The estimated annual percentage changes (EAPCs) in the ASIR and in the ASDR were calculated to quantify the temporal trends in the ASIR and ASDR of schizophrenia. Results Globally there were 1.13 million (95% uncertainty interval [UI] = 1.00 to 1.28) incident schizophrenia cases and 12.66 million (95% UI = 9.48 to 15.56) DALYs due to schizophrenia in 2017. The global ASIR decreased slightly from 1990 to 2017 (EAPC = −0.124, 95% UI = −0.114 to −0.135), while the ASDR was stable. The number of incident cases, DALYs, ASIR and ASDR were higher for males than for females. The incident rate and DALYs rate were highest among those aged 20–29 and 30–54 years, respectively. ASIR and ASDR were highest in East Asia in 2017, at 19.66 (95% UI = 17.72 to 22.00) and 205.23 (95% UI = 153.13 to 253.34), respectively. In 2017, the ASIR was highest in countries with a high-moderate sociodemographic index (SDI) and the ASDR was highest in high-SDI countries. We also found that the EAPC in ASDR was negatively correlated with the ASDR in 1990 (P = 0.001, ρ = −0.23). Conclusion The global burden of schizophrenia remains large and continues to increase, thereby increasing the burden on health-care systems. The reported findings should be useful for resource allocation and health services planning for the increasing numbers of patients with schizophrenia in ageing societies.


Author(s):  
Haijiang Dai ◽  
Quanyu Zhang ◽  
Arsalan Abu Much ◽  
Elad Maor ◽  
Amit Segev ◽  
...  

Abstract Aims To estimate the prevalence, incidence, mortality, and risk factors for atrial fibrillation (AF) in 195 countries and territories from 1990 to 2017. Methods and results Following the methodologies used in the Global Burden of Disease Study 2017, the prevalence, incidence, and mortality of AF were analysed by age, sex, year, socio-demographic index (SDI), and location. The percentage contributions of major risk factors to age-standardized AF deaths were measured by population attributable fractions. In 2017, there were 37.57 million [95% uncertainty interval (UI) 32.55–42.59] prevalent cases and 3.05 million (95% UI 2.61–3.51) incident cases of AF globally, contributing to 287 241 (95% UI 276 355–304 759) deaths. The age-standardized rates of prevalent cases, incident cases, and deaths of AF in 2017 and their temporal trends from 1990 to 2017 varied significantly by SDI quintile and location. High systolic blood pressure was the leading risk factor for AF age-standardized deaths [34.3% (95% UI 27.4–41.5)] in 2017, followed by high body mass index [20.7% (95% UI 11.5–32.2)] and alcohol use [9.4% (95% UI 7.0–12.2)]. Conclusion Our study has systematically and globally assessed the temporal trends of AF, which remains a major public heath challenge. Although AF mainly occurred in developed countries, the unfavourable trend in countries with lower SDI also deserves particular attention. More effective prevention and treatment strategies aimed at counteracting the increase in AF burden should be established in some countries.


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