scholarly journals Healthy adult vegetarians have better renal function than matched omnivores: a cross sectional study in China.

2020 ◽  
Author(s):  
Kaijie Xu ◽  
Xueying Cui ◽  
Bian Wang ◽  
Qingya Tang ◽  
Jianfang Cai ◽  
...  

Abstract Background: An appropriate diet is an important determinant of kidney health. However, the association between vegetarian diets and renal function is unclear. We aimed to study the association between vegetarian diets and renal function in healthy adults. Methods: A total of 269 vegetarians and 269 sex- and age-matched nonvegetarian omnivores were enrolled in this cross-sectional study. Basic characteristics and daily dietary intakes were assessed by face-to-face interviews. Blood samples were collected, and renal function was assessed by measuring blood urea nitrogen (BUN), serum creatinine (SCr), uric acid (UA) and the estimated glomerular filtration rate (eGFR). Blood pressure, fasting blood glucose and blood lipid profiles were also assessed.Results: The average age of the vegetarians was 35.4±8.6 years, 82.2% of whom were female. We evaluated the association between vegetarian diets and renal function using multivariate analysis. Compared with omnivores, vegetarians had lower BUN [β= -0.63, 95% confidence interval (CI): (-0.88 , -0.38)], SCr [β= -2.04, 95% CI:(-4.10, 0.02)], and UA levels [β= -15.15, 95% CI: (-27.81, -2.50)] and higher eGFRs [β= 4.04, 95% CI: (0.30, 7.78)] after adjusting for sex, age, body mass index (BMI), physical activity, alcohol consumption, smoking status, low-density lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL), systolic pressure and fasting blood glucose. Further analysis of food composition and renal function showed that dietary fiber intake was significantly negatively associated with BUN [β= -0.02, 95% CI: (-0.03, 0.00)], SCr [β= -0.14, 95% CI: (-0.25, 0.04)], and UA levels [β= -0.72, 95% CI: (-1.36, 0.07)] and positively associated with the eGFR [β= 0.20, 95% CI: (0.00, 0.40)]. Conclusions: Healthy adult vegetarians have better renal function than omnivores, and the higher dietary fiber intake associated with vegetarian diets may contribute to the protective effect on renal function.

2020 ◽  
Author(s):  
Kaijie Xu ◽  
Xueying Cui ◽  
Bian Wang ◽  
Qingya Tang ◽  
Jianfang Cai ◽  
...  

Abstract Background: An appropriate diet is an important determinant of kidney health. However, the association between vegetarian diets and renal function is unclear. We aimed to study the association between vegetarian diets and renal function in healthy adults. Methods: A total of 269 vegetarians and 269 sex- and age-matched nonvegetarian omnivores were enrolled in this cross-sectional study. Basic characteristics and daily dietary intakes were assessed by face-to-face interviews. Blood samples were collected, and renal function was assessed by measuring blood urea nitrogen (BUN), serum creatinine (SCr), uric acid (UA) and the estimated glomerular filtration rate (eGFR). Blood pressure, fasting blood glucose and blood lipid profiles were also assessed.Results: The average age of the vegetarians was 35.4±8.6 years, 82.2% of whom were female. We evaluated the association between vegetarian diets and renal function using multivariate analysis. Compared with omnivores, vegetarians had lower BUN [β= -0.63, 95% confidence interval (CI): (-0.88 , -0.38)], SCr [β= -2.04, 95% CI:(-4.10, 0.02)], and UA levels [β= -15.15, 95% CI: (-27.81, -2.50)] and higher eGFRs [β= 4.04, 95% CI: (0.30, 7.78)] after adjusting for sex, age, body mass index (BMI), physical activity, alcohol consumption, smoking status, low-density lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL), systolic pressure and fasting blood glucose. Further analysis of food composition and renal function showed that dietary fiber intake was significantly negatively associated with BUN [β= -0.02, 95% CI: (-0.03, 0.00)], SCr [β= -0.14, 95% CI: (-0.25, 0.04)], and UA levels [β= -0.72, 95% CI: (-1.36, 0.07)] and positively associated with the eGFR [β= 0.20, 95% CI: (0.00, 0.40)]. Conclusions: Healthy adult vegetarians have better renal function than omnivores, and the higher dietary fiber intake associated with vegetarian diets may contribute to the protective effect on renal function.


2020 ◽  
Author(s):  
Kaijie Xu ◽  
Xueying Cui ◽  
Bian Wang ◽  
Qingya Tang ◽  
Jianfang Cai ◽  
...  

Abstract Background Appropriate diet is an important determinant of kidney health. However, the association between vegetarian diets and renal function is unclear. Object We aimed to study the association between vegetarian diets and renal function in healthy adults. Design A total of 269 vegetarians (aged 34.5±8.7 years) and 269 sex- and age-matched nonvegetarian omnivores were enrolled in this cross-sectional study. Basic characteristics as well as daily dietary intakes were assessed by face-to-face interviews. Blood samples were collected, and renal function was assessed by measuring blood urea nitrogen (BUN), creatinine (Cr), uric acid (UA) and estimated glomerular filtration rate (eGFR). Blood pressure, fasting blood glucose and blood lipid profiles were also assessed. Results The average age of the vegetarians was 35.4±8.6 years, 82.2% of whom were female. We evaluated the association between vegetarian diets and renal function by using multivariate analysis. Compared with omnivores, vegetarians had lower BUN (β= -0.63, 95% CI: -0.88 to -0.38), SCr (β= -2.07, 95% CI: -4.21 to -0.061), UA (β= -15.17, 95% CI: -27.81 to -2.53) and higher eGFR levels (β= 4.09, 95% CI: 0.23 to 7.96) after adjusting for sex, age, BMI, physical activity, alcohol consumption, smoking status, LDL, HDL, systolic pressure and fasting blood glucose. Further analysis of food composition and renal function showed that dietary fiber intake was significantly negatively associated with BUN [β= -0.02, 95% CI:(-0.03, 0.00)], SCr [β= -0.14, 95% CI:(-0.25, 0.04)], and UA [β= -0.72, 95% CI:(-1.36, 0.07)] and positively associated with eGFR [β= 0.20, 95% CI:(0.00, 0.40)]. Conclusions Healthy adult vegetarians have better renal function than omnivores, and the higher dietary fiber intake associated with vegetarian diets may contribute to the protective effect on renal function.


2019 ◽  
Author(s):  
Kaijie Xu ◽  
Xueying Cui ◽  
Bian Wang ◽  
Qingya Tang ◽  
Jianfang Cai ◽  
...  

Abstract Background Appropriate diet is an important determinant of kidney health. However, the association between vegetarian diets and renal function is unclear.Object We aimed to study the association between vegetarian diets and renal function in healthy adults.Design A total of 269 vegetarians (aged 34.5±8.7 years) and 269 sex- and age-matched nonvegetarian omnivores were enrolled in this cross-sectional study. Basic characteristics as well as daily dietary intakes were assessed by face-to-face interviews. Blood samples were collected, and renal function was assessed by measuring blood urea nitrogen (BUN), creatinine (Cr), uric acid (UA) and estimated glomerular filtration rate (eGFR). Blood pressure, fasting blood glucose and blood lipid profiles were also assessed.Results The average age of the vegetarians was 35.4±8.6 years, 82.2% of whom were female. We evaluated the association between vegetarian diets and renal function by using multivariate analysis. Compared with omnivores, vegetarians had lower BUN (β= -0.63, 95% CI: -0.88 to -0.38), SCr (β= -2.07, 95% CI: -4.21 to -0.061), UA (β= -15.17, 95% CI: -27.81 to -2.53) and higher eGFR levels (β= 4.09, 95% CI: 0.23 to 7.96) after adjusting for sex, age, BMI, physical activity, alcohol consumption, smoking status, LDL, HDL, systolic pressure and fasting blood glucose. Further analysis of food composition and renal function showed that dietary fiber intake was significantly negatively associated with BUN [β= -0.02, 95% CI:(-0.03, 0.00)], SCr [β= -0.14, 95% CI:(-0.25, 0.04)], and UA [β= -0.72, 95% CI:(-1.36, 0.07)] and positively associated with eGFR [β= 0.20, 95% CI:(0.00, 0.40)].Conclusions Healthy adult vegetarians have better renal function than omnivores, and the higher dietary fiber intake associated with vegetarian diets may contribute to the protective effect on renal function.


2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Kaijie Xu ◽  
Xueying Cui ◽  
Bian Wang ◽  
Qingya Tang ◽  
Jianfang Cai ◽  
...  

Author(s):  
Anand N. ◽  
Vidya T. A.

Background: Metabolic syndrome includes a constellation of various metabolic abnormalities that have been associated with cardiovascular disease, stroke and all-cause mortality in the general population. It has now been established that it is also associated with renal dysfunction. This study was done to assess renal function in metabolic syndrome in Indian population as well as its correlation with different parameters of the metabolic syndrome.Methods: A cross-sectional study was conducted in a university hospital from 2014 - 2015. Renal functions were studied in 100 obese individuals, 50 with and 50 without metabolic syndrome after informed consent and the results were analysed.Results: 100 obese individuals, 50 with and 50 without metabolic syndrome were compared. All underwent a physical examination and relevant investigations. All parameters of renal function showed significant derangement in cases as compared to controls. 38 patients (76%) among the cases (N=50) of metabolic syndrome had altered renal functions versus 9 patients (18%) among controls (n=50). Individually, there was a significant correlation of altered renal function (reduced estimated glomerular filtration rate eGFR and presence of microalbuminuria) with fasting blood glucose and systolic blood pressure (p=0.001), diastolic pressure (p=0.003) and triglyceride levels (p=0.036). High density lipoprotein-cholesterol levels did not show a significant correlation.Conclusions: Obese individuals with metabolic syndrome have significant derangement of renal functions as compared to those without metabolic syndrome. Most parameters of the syndrome are also independently associated with alteration of renal functions.


2020 ◽  
Vol 29 (6) ◽  
pp. 565-571
Author(s):  
Ju Young Lee ◽  
Sae Rom Lee ◽  
Sang Yeoup Lee

<b><i>Objectives:</i></b> To investigate the prevalence of asymptomatic coronary artery stenosis (CAS) using coronary computed tomography angiography (CCTA) in Korean men with erectile dysfunction (ED). <b><i>Subjects and Methods:</i></b> A cross-sectional study was conducted on 108 men who underwent CCTA at a health promotion center in Pusan National University Yangsan Hospital. Each subject who was evaluated for ED using the International Index of Erectile Dysfunction (IIEF) questionnaire did not have a past history or symptoms of coronary artery disease (CAD). We assessed the association between ED and CCTA-based CAS. <b><i>Results:</i></b> The overall prevalence of ED was 57.4%; furthermore, age (<i>p</i> = 0.001) and fasting blood glucose (<i>p =</i>0.035) were the metabolic risk factors that were most significantly associated with the presence of ED. The overall frequency of CAS was 31.5%, and ED (<i>p</i> = 0.022), age (<i>p</i> &#x3c; 0.001), fasting blood glucose (<i>p</i> = 0.021), and total cholesterol/high-density lipoprotein cholesterol (<i>p</i> = 0.029) were significantly associated with the presence of CAS. The prevalence of CAS was 40.3 and 19.6% in the ED and non-ED groups, respectively. Men with ED were 2.778 times more likely to present with CAS than those without ED (OR 2.778, 95% CI 1.143–6.749, <i>p</i> = 0.024); however multivariate logistic regression analysis, while controlling for age, total cholesterol/high-density lipoprotein cholesterol, and fasting blood glucose, suggested the absence of a significant association between ED and CCTA-based CAS. <b><i>Conclusion:</i></b> This study shows that CCTA-based CAS is a common phenomenon in men who have ED. Furthermore, ED patients without cardiac symptoms need to be investigated for the possibility of hidden CAD.


2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Dilnessa Fentie ◽  
Tariku Derese ◽  
Bekele Yazie ◽  
Yibeltal Getachew

Abstract Background Metabolic syndrome is a major public health challenge in both developed and developing countries. The burden of this disease is high, even in patients with psychiatric disorders. However, very little is known about the association between metabolic syndrome and psychiatric illness in Ethiopia. Therefore, the aim of this study was to investigate the magnitude of metabolic syndrome and its components among psychiatric clients. Methods A comparative cross-sectional study was undertaken between psychiatric patients and age—and sex-matched non-psychiatric controls at the Dilchora referral hospital. The study included 192 study participants (96 psychiatric patients and 96 non- psychiatric controls from general medical and surgical patients). The National Cholesterol Education Program: Adult Treatment Panel III criteria were used to diagnose metabolic syndromes. The data were cleaned and analyzed using the Statistical Package for Social Sciences, Version 21. All intergroup comparisons for continuous data were performed using an independent sample t-test, whereas categorical data were analyzed using the Chi-square test. Logistic regression analysis was used to identify the association between metabolic syndrome and the associated variables. Results The magnitude of metabolic syndrome among psychiatric patients was 36.5% (95%CI: 27.6, 47.4) compared to non-psychiatric control patients, 21.9% (95%CI: 13.5, 30.3), p = 0.02. The prevalence of MetS components, such as waist circumference (25.0% vs. 14.3%), lower-high density lipoprotein level (35.4% vs. 20.8%), higher systolic blood pressure (41.7% vs. 29.2%) and higher fasting blood glucose (40.6% vs. 18.8%) showed statistically significant differences between the exposed and non-exposed groups. Age greater than 50 years (AOR: 2.8, CI: 1.14, 20.0, p < 0.05); being female (AOR: 7.4, CI: 2.0, 27.6, p < 0.05), being urban residence (AOR: 6.4, CI: 2.2, 20.6, p < 0.05), ever alcohol intake (AOR: 5.3, CI: 1.3, 21.2), being physically inactive (AOR: 3.52, CI: 1.1, 12.9, p < 0.05) and family history of hypertension (AOR: 2.52, CI: 1.1, 12.2, p < 0.05) were independent predictors of metabolic syndrome (p < 0.05). Conclusions There is a high burden of metabolic syndrome and its components in patients with severe psychiatric disorders. Therefore, screening and mitigation strategies for metabolic syndrome and their components should be implemented in the management of psychiatric disorders.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kyuwoong Kim ◽  
Yoonjung Chang

AbstractNutrient intake for adult cancer survivors is of clinical importance for managing metabolic health. Whether dietary fiber intake is associated with metabolic syndrome (MetS) or not in adult cancer survivors is uncertain. We aim to investigate the association between dietary fiber intake and MetS in adult cancer survivors using a population-based cross-sectional study. A study sample of 1301 adult cancer survivors aged more than 20 years from the sixth and seventh Korea Nutrition Examination Survey (KNHANES) from 2013 to 2018 was identified. Odds ratio (OR) and 95% confidence intervals (95% CI) were estimated from multiple logistic regression adjusted for sociodemographic factors, health behavior, and nutritional status. Among 1,301 adult cancer survivors identified from the KNHANES 2013–2018, the mean dietary fiber intake was 28.1 g/day (standard error, 0.54). Compared to the first quintile of dietary fiber intake, the adjusted ORs and 95% CIs for MetS in the second, third, fourth, and fifth quintiles of dietary fiber intake were 0.84 (0.27–2.61), 0.77 (0.16–3.74), 0.55 (0.14–2.22), and 0.26 (0.05–1.39), respectively (p value for trend = 0.0007). Our findings suggest that high dietary fiber intake is marginally associated with reduced odds of MetS in adult cancer survivors.


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