Sex differences in the association between self-reported sleep duration, insomnia symptoms and cardiometabolic risk factors: cross-sectional findings from from Brazilian Longitudinal Study of Adult Health

Abstract Background: The U-shaped associations between sleep durations and cardiometabolic risk factors (glycated hemoglobin levels, obesity, hypertriglyceridemia, hypertension and HDL-cholesterol levels) are still inconclusive. Moreover, as sleep is comprised of quantitative and qualitative aspects, exploring both insomnia symptoms and sleep duration are relevant when evaluating the potential effects of sleep problems on health. The aim was to evaluate sex-specific associations between sleep problems and cardiometabolic risk factors. Methods: This cross-sectional study used data from wave two of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil), including 7,491 women and 6,232 men. Questionnaires were administered to provide information about socioeconomic conditions, lifestyle, and sleep characteristics. A 12-hour fasting blood sample was drawn to measure serum cholesterol, triglycerides, and glycated hemoglobin. Blood pressure, weight and height were also measured using standard equipment. Generalized additive models were used to evaluate the curve shape of the relationship between self-reported sleep duration and the outcomes. Logistic regression was performed to investigate the magnitude of the associations of self-reported sleep duration, insomnia symptoms, and short sleep plus insomnia symptoms with cardiometabolic risk factors. Results: For women, self-reported sleep duration and insomnia symptoms (either separately or linked to short sleep duration) were associated with obesity, hypertension and glycated hemoglobin after adjusting for the confounders. The magnitudes of the associations between self-reported short sleep duration plus insomnia symptoms and the outcomes were slightly increased, considering sleep duration or insomnia symptoms separately. For men, both long sleep duration and insomnia symptoms were associated with hypertriglyceridemia after adjusted for the confounders. Conclusion: These findings suggest possible sex-specific patterns, since obesity, hypertension and high glycated hemoglobin were associated with self-reported sleep duration and insomnia symptoms in women, but not in men, and reinforce the importance of considering quantitative and qualitative aspects of sleep for the prevention and management of the outcomes.

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Sex differences in the association between self-reported sleep duration, insomnia symptoms and cardiometabolic risk factors: cross-sectional findings from ELSA-Brasil

10.21203/rs.2.18615/v1 ◽

2019 ◽

Author(s):

Aline Silva-Costa ◽

Lucia Rotenberg ◽

Aline Araujo Nobre ◽

Dora Chor ◽

Estela Aquino ◽

...

Keyword(s):

Risk Factors ◽

Sleep Duration ◽

Cardiometabolic Risk ◽

Glycated Hemoglobin ◽

Sleep Problems ◽

Cardiometabolic Risk Factors ◽

Short Sleep Duration ◽

Cross Sectional ◽

Short Sleep ◽

Insomnia Symptoms

Abstract Background: The U-shaped associations between sleep durations and cardiometabolic risk factors (glycated hemoglobin levels, obesity, hypertriglyceridemia, hypertension and HDL-Cholesterol levels) are still inconclusive. Moreover, as sleep is comprised of quantitative and qualitative aspects, exploring both insomnia symptoms and sleep duration are relevant when evaluating the potential effects of sleep problems on health. The aim was to evaluate sex-specific associations between sleep problems and cardiometabolic risk factors. Methods: This cross-sectional study used data from wave two of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil), including 7,491 women and 6,232 men. Questionnaires were administered to provide information about socioeconomic conditions, lifestyle, and sleep characteristics. A 12-hour fasting blood sample was drawn to measure serum cholesterol, triglycerides, and glycated hemoglobin. Blood pressure, weight and height were also measured using standard equipment. Generalized additive models were used to evaluate the curve shape of the relationship between self-reported sleep duration and the outcomes. Logistic regression was performed to investigate the magnitude of the associations of self-reported sleep duration, insomnia symptoms, and short sleep plus insomnia symptoms with cardiometabolic risk factors. Results: For women, self-reported sleep duration and insomnia symptoms (either separately or linked to short sleep duration) were associated with obesity, hypertension and glycated hemoglobin after adjusting for the confounders. The magnitudes of the associations between self-reported short sleep duration plus insomnia symptoms and the outcomes were slightly increased, considering sleep duration or insomnia symptoms separately. For men, both long sleep duration and insomnia symptoms were associated with hypertriglyceridemia after adjusted for the confounders. Conclusion: These findings suggest possible sex-specific patterns, since obesity, hypertension and high glycated hemoglobin were associated with self-reported sleep duration and insomnia symptoms in women, but not in men, and reinforce the importance of considering quantitative and qualitative aspects of sleep for the prevention and management of the outcomes.

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Sex differences in the association between self-reported sleep duration, insomnia symptoms and cardiometabolic risk factors: cross-sectional findings from Brazilian longitudinal study of adult health

Archives of Public Health ◽

10.1186/s13690-020-00429-8 ◽

2020 ◽

Vol 78 (1) ◽

Author(s):

Aline Silva-Costa ◽

Lucia Rotenberg ◽

Aline A. Nobre ◽

Dora Chor ◽

Estela M. Aquino ◽

...

Keyword(s):

Risk Factors ◽

Sex Differences ◽

Longitudinal Study ◽

Sleep Duration ◽

Cardiometabolic Risk ◽

Cardiometabolic Risk Factors ◽

Adult Health ◽

Cross Sectional ◽

Insomnia Symptoms

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Sleep and Association With Cardiovascular Risk Among Midwestern US Firefighters

Frontiers in Endocrinology ◽

10.3389/fendo.2021.772848 ◽

2021 ◽

Vol 12 ◽

Author(s):

Juan Luis Romero Cabrera ◽

Mercedes Sotos-Prieto ◽

Antonio García Ríos ◽

Steven Moffatt ◽

Costas A. Christophi ◽

...

Keyword(s):

Risk Factors ◽

Sleep Quality ◽

Sleep Duration ◽

Body Fat ◽

Cardiometabolic Risk ◽

Cross Sectional Study ◽

Cardiometabolic Risk Factors ◽

Short Sleep Duration ◽

Cross Sectional ◽

Short Sleep

IntroductionCardiovascular disease is the leading cause of on-duty fatalities among U.S. firefighters. Research has demonstrated that many modifiable risk factors are contributors to the high prevalence of cardiometabolic risk factors. The current study aimed to assess whether sleep is associated with cardiometabolic risk factors among Indianapolis firefighters. The findings could support improving sleep hygiene in this population.Material and MethodsThis cross-sectional study was conducted from the baseline data of eligible firefighters enrolled in “Feeding America’s Bravest”, a Mediterranean diet lifestyle intervention within the Indiana Fire Departments. Participants’ sleep quality was categorized as “good” (≤ 8 points) or “bad” (>8 points) by a sleep quality questionnaire based on some questions from Pittsburgh Sleep Quality Index. In addition, firefighters’ sleep duration was stratified based on the number of hours slept per night (≤6 as “short sleep” or >6 hours as normal). Linear and logistic regression models were used to examine the association of sleep with cardiometabolic risk factors.ResultsA total of 258 firefighters were included. Bad sleepers had higher weight, greater waist circumference, higher body mass index (BMI), and increased body fat (all p<0.01) compared to good sleepers. Similarly, participants with short sleep duration were heavier (p<0.02), had greater BMI (p<0.02) and increased body fat (p<0.04) compared with participants with normal sleep duration. Both bad and short sleepers had a higher prevalence of hypertension and obesity (p <0.05).ConclusionsOur study supports that both sleep quality and quantity are associated with cardiometabolic risk among firefighters.

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Association of short sleep duration with cardiometabolic risk factors in a population of rural Nigerian women: A cross-sectional study

International Journal of Medicine and Health Development ◽

10.4103/ijmh.ijmh_17_20 ◽

2020 ◽

Vol 25 (2) ◽

pp. 120

Author(s):

EkenechukwuE Young ◽

ChidimmaB Nwatu ◽

BelonwuM Onyenekwe ◽

ChiomaH Ezike ◽

EjioforT Ugwu ◽

...

Keyword(s):

Risk Factors ◽

Sleep Duration ◽

Cardiometabolic Risk ◽

Cross Sectional Study ◽

Cardiometabolic Risk Factors ◽

Sectional Study ◽

Short Sleep Duration ◽

Cross Sectional ◽

Nigerian Women ◽

Short Sleep

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OSA, Short Sleep Duration, and Their Interactions With Sleepiness and Cardiometabolic Risk Factors in Adults

CHEST Journal ◽

10.1016/j.chest.2018.12.003 ◽

2019 ◽

Vol 155 (6) ◽

pp. 1190-1198 ◽

Cited By ~ 12

Author(s):

Luciano F. Drager ◽

Ronaldo B. Santos ◽

Wagner A. Silva ◽

Barbara K. Parise ◽

Soraya Giatti ◽

...

Keyword(s):

Risk Factors ◽

Sleep Duration ◽

Cardiometabolic Risk ◽

Cardiometabolic Risk Factors ◽

Short Sleep Duration ◽

Short Sleep

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Short Sleep Duration and Insomnia Symptoms were Associated with Lower Happiness Levels in Chinese Adults in Hong Kong

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph16122079 ◽

2019 ◽

Vol 16 (12) ◽

pp. 2079 ◽

Cited By ~ 3

Author(s):

Sheng Zhi Zhao ◽

Man Ping Wang ◽

Kasisomayajula Viswanath ◽

Agnes Lai ◽

Daniel Yee Tak Fong ◽

...

Keyword(s):

Older Adults ◽

Sleep Duration ◽

Sleep Problems ◽

Early Morning ◽

Population Based ◽

Short Sleep Duration ◽

Younger Adults ◽

Study Objective ◽

Short Sleep ◽

Insomnia Symptoms

Study objective: To examine the association of sleep duration and insomnia symptoms with happiness. Methods: A random sample of 1691 Chinese adult (mean age 54 ± 20.1, male 51%) were interviewed in a population-based telephone survey. Happiness was measured by the subjective happiness scale (SHS) and the one-item global happiness index (GHI). Information on sleep included mean past seven-day sleep duration (<6 h, ≥6 to <8 h and ≥8 h) and insomnia symptoms: Difficulty in initiating sleep (DIS), difficulty in maintaining sleep (DMS), and early morning awakening (EMA). Adjusted beta-coefficient (β) of SHS and adjusted odds ratio (aOR) of GHI in relation to sleep problems were calculated. Interaction effects by age (18–65 vs. ≥65) and by sex were assessed. Results: Compared to ≥8 h of sleep, having <6 h of sleep had lower SHS (adjusted β −0.32, 95% CI −0.46 to −0.17) and GHI (aOR 0.54, 95% CI 0.38 to 0.78). The associations were stronger in younger adults and in women (p < 0.05). DIS, DMS, and EMA were associated with lower SHS (adjusted β ranged from −0.20 to −0.06) and GHI (aOR ranged from 0.57 to 0.89). Dose-response association between the number of insomnia symptoms and lower SHS was observed (p < 0.001). These associations were generally stronger in older adults and among women. Conclusions: Lower levels of happiness were observed, particularly in younger adults and females with short sleep duration and older adults and females with insomnia symptoms. Prospective studies are needed to confirm the findings and understand the mechanisms between sleep and happiness.

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