scholarly journals Prevalence and factors associated with meconium stained amniotic fluid in a tertiary hospital, Northwest Ethiopia: A cross sectional study

2019 ◽  
Author(s):  
Enyew Abate ◽  
Kassahun Alamirew ◽  
Eleni Admassu ◽  
Awoke Derbie

Abstract Background Meconium is a green viscous fluid and its passage normally occurs within the first 24-48 hours after birth. However, fetuses could pass meconium before or during labor and mostly intrauterine passage was found to be associated with different feto-maternal stress factors resulting in increased risk of perinatal morbidity and mortality. In Ethiopia little is known about the proportion and associated factors for meconium stained amniotic fluid (MSAF). The aim of the study was to assess the proportion and associated factors of MSAF in women who came for labor and delivery service in a tertiary hospital in Ethiopia.Methods A cross sectional study was conducted from 1st June to 31 August, 2018 on 606 laboring mothers at Felege Hiwot Referral Hospital, northwest Ethiopia. Study participants were selected using a systematic random sampling technique. Data was collected using interviewer administered structured questionnaire. Data entry and analysis were made by using Epi-data v3.1 and SPSS v24, respectively. Both descriptive & analytical statistics were computed. Statistical significance was set at P < 0.05. Logistic regression was used to explore factors associated with MSAF.Results The proportion of MSAF was at 149 (24.6%) [95%CI: 21.3-28.2%]. Nonreassuring fetal heart rate pattern (AOR: 21.9,95% CI: 10.96-43.83), post term pregnancy (4.54,95% CI: 2.24-9.20), duration of labor more than 15 hours (AOR: 2.83,95% CI: 1.76-4.53), pregnancy induced hypertension (AOR: 2.43, 95% CI: 1.45-4.05), oligohydramnios (AOR: 2.53, 95% CI: 1.25-5.12) inter pregnancy interval less than 2 years (AOR: 2.24,95% CI: 1.12-4.51) and monthly family income less than 5000 Ethiopian Birr (185 United States Dollar) (AOR: 2.03, 95% CI:1.18-3.51) were significantly associated with MSAF.Conclusions The proportion of MSAF was at 24.6% which was higher than a previous study done in Ethiopia and elsewhere. Non-reassuring fetal heart rate pattern, post term pregnancy, duration of labor more than 15 hours, pregnancy induced hypertension, oligohydramnios, inter pregnancy interval less than 2 years and monthly family income less than 5000 Ethiopian Birr were factors associated with an increased risk for MSAF. Health professionals should assess laboring women for the presence of these factors and should stay alert to detect MSAF early and to act accordingly.

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Enyew Abate ◽  
Kassahun Alamirew ◽  
Eleni Admassu ◽  
Awoke Derbie

Background. Fetal bowel could pass meconium, a green viscous fluid, before or during labour and most intrauterine passage of meconium is associated with several fetomaternal factors that lead to increased risk of perinatal morbidity and mortality. Given that there is a paucity of data, this study was conducted to assess the proportion and associated factors of meconium-stained amniotic fluid (MSAF) in women who came for labour and delivery service in a tertiary hospital. Methods. A cross-sectional study was conducted from 1 June to 31 August 2018 among 606 labouring mothers at Felege Hiwot Referral Hospital, northwest Ethiopia. Study participants were selected using a systematic random sampling technique. Data were collected using an interviewer-administered pretested questionnaire and data checklist. Factors associated with MSAF were explored using multivariable logistic regression analysis. Results. MSAF occurred in 24.6% (149/606) of pregnancies. Nonreassuring fetal heart rate patterns (Adjusted Odds Ratio [AOR]: 21.9, 95% Confidence interval [95% CI]: 10.96–43.83), postterm pregnancy (AOR: 4.54, 95% CI: 2.24–9.20), duration of labour more than 15 hours (AOR: 2.83, 95% CI: 1.76–4.53), pregnancy-induced hypertension (AOR: 2.43, 95% CI: 1.45–4.05), oligohydramnios (AOR: 2.53, 95% CI: 1.25–5.12), interpregnancy interval less than 2 years (AOR: 2.24, 95% CI: 1.12–4.51), and monthly family income less than 5000 Ethiopian Birr (185 USD) (AOR: 2.03, 95% CI: 1.18–3.51) were significantly associated with MSAF. Conclusions. In this study, the proportion of MSAF was at 24.6% which was higher than a previous report in Ethiopia. Nonreassuring fetal heart rate pattern, postterm pregnancy, duration of labour more than 15 hours, pregnancy-induced hypertension, oligohydramnios, interpregnancy interval less than 2 years, and monthly family income less than 5000 Ethiopian Birr were factors associated with an increased risk for MSAF. Therefore, interventions aimed at detecting MSAF early should consider these factors.


2018 ◽  
Vol 104 (2) ◽  
pp. 134-140 ◽  
Author(s):  
Anna Francis ◽  
Madeleine S Didsbury ◽  
Anita van Zwieten ◽  
Kerry Chen ◽  
Laura J James ◽  
...  

ObjectiveThe aim was to compare quality of life (QoL) among children and adolescents with different stages of chronic kidney disease (CKD) and determine factors associated with changes in QoL.DesignCross-sectional.SettingThe Kids with CKD study involved five of eight paediatric nephrology units in Australia and New Zealand.PatientsThere were 375 children and adolescents (aged 6–18 years) with CKD, on dialysis or transplanted, recruited between 2013 and 2016.Main outcome measuresOverall and domain-specific QoL were measured using the Health Utilities Index 3 score, with a scale from −0.36 (worse than dead) to 1 (perfect health). QoL scores were compared between CKD stages using the Mann-Whitney U test. Factors associated with changes in QoL were assessed using multivariable linear and ordinal logistic regression.ResultsQoL for those with CKD stages 1–2 (n=106, median 0.88, IQR 0.63–0.96) was higher than those on dialysis (n=43, median 0.67, IQR 0.39–0.91, p<0.001), and similar to those with kidney transplants (n=135, median 0.83, IQR 0.59–0.97, p=0.4) or CKD stages 3–5 (n=91, 0.85, IQR 0.60–0.98). Reductions were most frequent in the domains of cognition (50%), pain (42%) and emotion (40%). The risk factors associated with decrements in overall QoL were being on dialysis (decrement of 0.13, 95% CI 0.02 to 0.25, p=0.02), lower family income (decrement of 0.10, 95% CI 0.03 to 0.15, p=0.002) and short stature (decrement of 0.09, 95% CI 0.01 to 0.16, p=0.02).ConclusionsThe overall QoL and domains such as pain and emotion are substantially worse in children on dialysis compared with earlier stage CKD and those with kidney transplants.


Toxins ◽  
2019 ◽  
Vol 11 (1) ◽  
pp. 22 ◽  
Author(s):  
Sâmella S. Oliveira ◽  
Eliane C. Alves ◽  
Alessandra S. Santos ◽  
João Pedro T. Pereira ◽  
Lybia Kássia S. Sarraff ◽  
...  

Bothrops snakebites usually present systemic bleeding, and the clinical–epidemiological and laboratorial factors associated with the development of this manifestation are not well established. In this study, we assessed the prevalence of Bothrops snakebites with systemic bleeding reported at the Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, in Manaus, Amazonas State, Brazil, and the clinical–epidemiological and laboratorial factors associated with systemic bleeding. This is an observational, cross-sectional study carried out between August, 2013 and July, 2016. Patients who developed systemic bleeding on admission or during hospitalization were considered cases, and those with non-systemic bleeding were included in the control group. Systemic bleeding was observed in 63 (15.3%) of the 442 Bothrops snakebites evaluated. Bothrops snakebites mostly occurred in males (78.2%), in rural areas (89.0%) and in the age group of 11 to 30 years old (40.4%). It took most of the patients (59.8%) less than 3 h to receive medical assistance. Unclottable blood (AOR = 3.11 (95% CI = 1.53 to 6.31; p = 0.002)) and thrombocytopenia (AOR = 4.52 (95% CI = 2.03 to 10.09; p < 0.001)) on admission were independently associated with systemic bleeding during hospitalization. These hemostatic disorders on admission increase the chances of systemic bleeding during hospitalization. Prospective studies are needed to clarify the pathophysiology of systemic bleeding in Bothrops snakebites in the Amazon region.


Pain Medicine ◽  
2016 ◽  
Vol 17 (10) ◽  
pp. 1917-1922 ◽  
Author(s):  
Dong Hoon Lee ◽  
Ji Eun Park ◽  
Duck Mi Yoon ◽  
Kyung Bong Yoon ◽  
Kiwook Kim ◽  
...  

2021 ◽  
Vol 1 (1) ◽  
pp. 27-33
Author(s):  
Wei Chern Ang ◽  
Nur Syafiqah Zulkepli ◽  
Nur Safinaz Mukhtar ◽  
Nur Atikah Zulkefli

Introduction: Malaysia will be a full aging nation by 2030. The elderly (aged >65 years old) population often has multiple comorbidities, which increases the risk of polypharmacy and potentially inappropriate medications (PIMs). This study aims to investigate the prevalence, factors associated with PIMs among elderly outpatients, and its burden of direct pharmacotherapy cost to the Ministry of Health Malaysia. Materials and method:  A cross-sectional study involving clinic prescriptions among the elderly with more than one-month prescribing duration received from a tertiary hospital specialist clinic pharmacy from March to April 2017. Patient identifiers were screened using the Pharmacy Information System (PhIS) by including prescriptions from other clinics while excluding multiple visits and duplicate prescriptions. Patients were categorised as PIM group and non-PIM groups using Beers Criteria 2015. Logistic regression analysis was conducted to examine the factors associated with PIMs. The median monthly prescription cost was compared between PIM and non-PIM groups by Mann-Whitney test. Results: Among 472 patients, 39.4% of patients had at least one PIM while 60.6% of patients did not receive any PIM. The number of medications prescribed was an independent risk factor contributing to PIMs (OR:2.04; 95% CI:1.40, 2.97). The median monthly prescription cost for the PIM group was MYR 29.50 (?USD 7.53) which was not statistically significant (p=0.735) compared with the non-PIM group which was MYR 28.50 (USD 7.28).  Conclusion: PIM was frequently prescribed in our setting with the number of medications as the only factor. However, the prescribing of PIM did not add nor reduce the direct cost of pharmacotherapy.


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