scholarly journals Antimicrobial Sensitivity pattern of Bacteria Causing Urinary Tract Infection among Diabetic Patients

2020 ◽  
Author(s):  
Pratima Thapa ◽  
Anita Sunar ◽  
Dipendra Lamichanne ◽  
Apeksha K.C ◽  
Arjan Dhungana ◽  
...  
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Diabetic Patient ◽  
High Rate ◽  
Diabetic Patients ◽  
Cross Sectional ◽  
Antimicrobial Sensitivity ◽  
Sensitivity Pattern ◽  
Highly Sensitive

Abstract Urinary tract infection is the presence and active multiplication of microorganism within the urinary tract. UTIs are group of infections that affects any part of urinary tract. The cross sectional descriptive study was conducted to determine the antibiotic susceptibility pattern of bacteria causing urinary tract infection in diabetic and non-diabetic patient from February 2016 to March 2016. Among the total 601 urine sample, 250 were diabetics and 351 were non diabetics. All samples were investigated by standard laboratory procedures. Out of diabetic patient 111(44.4%) were female and 139(55.6%) were male and among non-diabetic, 234(66.7%) were female and 117(33.3%) were male. The UTI prevalence rate was found to be 78 (13%) was statistically significant (p = 0.02), among the significant growth 6.8% diabetic and 6.2% non-diabetic. Escherichia coli (54) was the most predominant organism (42.5% in diabetic and 57.5% non-diabetic) followed by Staphylococcus aureus (8). Amikacin, Cotrimoxazole and Nitrofurantoin were most sensitive to E. coli isolated in diabetic and non-diabetic patients among the tested antimicrobials. High rate of resistance was observed with Norfloxacin and Nalidixic acid. Gentamicin, Cefotaxime, Cotrimoxazole and Ciprofloxacin were highly sensitive to S. aureus in diabetic patients while Oxacillin and Azithromycin were resistance and in non-diabetic patient highly sensitive antimicrobials were Azithromycin, Gentamicin, Cefotaxime, Cotrimoxazole, Vancomycin and Ofloxacin while Oxacillin was resistance. The antimicrobial susceptibility testing of bacterial isolates should be performed before the treatment of UTI. Key words : Diabetic, Urinary tract infection, Antimicrobial sensitivity.

scholarly journals Antimicrobial Sensitivity pattern of Bacteria Causing Urinary Tract Infection among Diabetic Patients

2020 ◽  
Author(s):  
Pratima Thapa ◽  
Anita Sunar ◽  
Dipendra Lamichanne ◽  
Apeksha K.C ◽  
Arjan Dhungana ◽  
...  
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Diabetic Patient ◽  
High Rate ◽  
Diabetic Patients ◽  
Cross Sectional ◽  
Antimicrobial Sensitivity ◽  
Sensitivity Pattern ◽  
Highly Sensitive

Abstract Urinary tract infection is the presence and active multiplication of microorganism within the urinary tract. UTIs are group of infections that affects any part of urinary tract. The cross sectional descriptive study was conducted to determine the antibiotic sensitivity pattern of bacteria causing urinary tract infection in diabetic and non-diabetic patient from February 2016 to March 2016. Among the total 601 urine sample, 250 were diabetics and 351 were non diabetics. All samples were investigated by standard laboratory procedures. Out of diabetic patient 111(44.4%) were female and 139(55.6%) were male and among non-diabetic, 234(66.7%) were female and 117(33.3%) were male. The UTI prevalence rate was found to be 78 (13%) was statistically significant (p = 0.02), among the significant growth 6.8% diabetic and 6.2% non-diabetic. Escherichia coli (54) was the most predominant organism (42.5% in diabetic and 57.5% non-diabetic) followed by Staphylococcus aureus (8). Amikacin, Cotrimoxazole and Nitrofurantoin were most sensitive to E. coli isolated in diabetic and non-diabetic patients among the tested antimicrobials. High rate of resistance was observed with Norfloxacin and Nalidixic acid. Gentamicin, Cefotaxime, Cotrimoxazole and Ciprofloxacin were highly sensitive to S. aureus in diabetic patients while Oxacillin and Azithromycin were resistance and in non-diabetic patient highly sensitive antimicrobials were Azithromycin, Gentamicin, Cefotaxime, Cotrimoxazole, Vancomycin and Ofloxacin while Oxacillin was resistance. The antimicrobial susceptibility testing of bacterial isolates should be performed before the treatment of UTI. Key words : Diabetic, Urinary tract infection, Antimicrobial sensitivity.

scholarly journals Uropathogenic Bacteria and Antimicrobial Sensitivity Pattern among Diabetic Patients with Urinary Tract Infection

2020 ◽  
pp. 85-92
Author(s):  
Pratima Thapa ◽  
Anita Sunar ◽  
Dipendra Lamichanne ◽  
Apeksha K. C. ◽  
Arjan Dhungana ◽  
...  
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Diabetic Patient ◽  
Diabetic Patients ◽  
Sensitivity Testing ◽  
Antimicrobial Sensitivity ◽  
Sensitivity Pattern ◽  
Highly Sensitive ◽  
Uropathogenic Bacteria

Urinary tract infection means the presence and active multiplication of microorganisms within the urinary tract that affects any part of urinary tract. A cross sectional descriptive study was conducted on 601 urine sample to determine the antibiotic sensitivity pattern of bacteria causing urinary tract infection in 250 diabetic and 351non-diabetic patients from February 2016 to March 2016. All samples were investigated by standard laboratory procedures. Out of diabetic patient 111 (44.4%) were female and 139 (55.6%) were male and among non-diabetic, 234 (66.7%) were female and 117(33.3%) were male. The UTI prevalence rate was found to be 13% was statistically significant (p= 0.02), among the significant growth 6.8% diabetic and 6.2% non-diabetic. Escherichia coli (54) was the most predominant organism (42.5% in diabetic and 57.5% non-diabetic) followed by Staphylococcus aureus (8). Amikacin, Cotrimoxazole and Nitrofurantoin were most sensitive to E. coli isolated in diabetic and non-diabetic patients among the tested antimicrobials. High rate of resistance was observed with Norfloxacin and Nalidixic acid. Gentamicin, Cefotaxime, Cotrimoxazole and Ciprofloxacin were highly sensitive to S. aureus in diabetic patients while Oxacillin and Azithromycin were resistance and in non-diabetic patient highly sensitive antimicrobials were Azithromycin, Gentamicin, Cefotaxime, Cotrimoxazole, Vancomycin and Ofloxacin while Oxacillin was resistance. The antimicrobial sensitivity testing of uropathogenic bacterial isolates should be performed before the initiation of treatment for UTI. Prevalance of uropathogenic bacteria and resistance rate should be monitored regularly.

scholarly journals The Pattern of Organism Causing Urinary Tract Infection in Diabetic and Non Diabetic Patients in Bangladesh

1970 ◽  
Vol 4 (1) ◽  
pp. 6-8 ◽  
Author(s):  
Md Hamza Saber ◽  
Lovely Barai ◽  
J Ashraful Haq ◽  
Md Shariful Alam Jilani ◽  
Jaheda Begum
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Diabetic Patient ◽  
Bacterial Resistance ◽  
Diabetic Patients ◽  
Beta Lactamase ◽  
Extended Spectrum Beta Lactamase ◽  
Extended Spectrum ◽  
Sensitivity Pattern

Urinary tract infection (UTI) is common both in the diabetic and non-diabetic patients. The widespread use of antimicrobial agents leads to emergence of resistant microorganisms. Since the pattern of bacterial resistance is constantly changing, the monitoring of the antimicrobial susceptibilities of the predominantly isolated organisms becomes more important. Aim of this study was to determine the etiologic agents and their antibiotic sensitivity pattern in both diabetic and non-diabetic patients with urinary tract infection (UTI). A total of 288 diabetics (196 female and 92 males) and 63 non diabetic patients (43 female and 20 males) with symptomatic UTI were included in this study. Among the study cases, 43.8% diabetic patients and 42.9% non-diabetic patients had positive growth from urine. Rate of isolation of Escherichia coli in diabetic was less (61.8%) compared to non diabetic (77.8%). Rate of other organisms isolated in diabetic and non diabetic patients were respectively: Klebsiella sp 6.9% vs 3.7%, Enterococcus 12.2% vs3.7%, Pseudomonas species 3.8% vs 0%, Candida species 4.6% versus 3.7%, Staphylococcus aureus 4.6% versus 7.4% etc. E coli isolated from diabetic patient was significantly (p<0.05) less sensitive to ceftriaxone, ceftazidime, cefuroxime, netilmicin, gentamicin, ciprofloxacin and nitrofurantoin than that of non diabetic patients. In addition, isolation rate of the Extended Spectrum Beta Lactamase producing gram negative bacilli was found higher among diabetic population (47.8%) compared to the non-diabetics (9.1%). Key words: Urinary tract infection (UTI), Diabetic and non diabetic patient, Extended Spectrum Beta Lactamase. DOI: http://dx.doi.org/10.3329/bjmm.v4i1.8461 BJMM 2011; 4(1): 6-8

scholarly journals Antimicrobial Sensitivity Pattern for Urine Isolates in Urinary Tract Infection

2019 ◽  
Vol 8 (4) ◽  
pp. 186-192
Author(s):  
Kiran Tauseef Bukhari ◽  
Haseeb Tauseef Bukhari ◽  
Humaira Zafar ◽  
Mudassira Zahid
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Phosphonic Acid ◽  
Urine Culture ◽  
Polymyxin B ◽  
Resistance Pattern ◽  
Cross Sectional ◽  
Antimicrobial Sensitivity ◽  
Sensitivity Pattern

Background: The increased frequency and management of antibiotic resistance pattern in urinary tract infection (UTI) is a challenging task for the clinicians. Therefore, the current study was planned to identify the microbial etiology of UTI and the most suitable antibiotics used. The objective of the study was to assess the frequency of antimicrobial sensitivity pattern in patients with urinary tract infection.Material and Methods: This cross-sectional study was carried out at Al Sayed Hospital, Kidney Centre, Rawalpindi over a period of seven months i.e. June 30, 2018 to January 30, 2019. A total of 152 patients were enrolled according to the inclusion and exclusion criteria of the study. Urine culture proceedings were done as per latest recommended guidelines of Clinical and Laboratory Standard Institute (CLSI) for UTI.Results: Regarding overall sensitivity of antibiotics for the pathogens of urine culture, highest sensitivity was observed for carbapenems (83.5%), followed by polymyxin B (72.3%), phosphonic acid derivatives (65.8%), aminoglycoside group (65.7%), extended spectrum penicillin (63.1%), imidazolidinedione (59.9%) and tetracycline (59.9%) groups. The least sensitivity was observed for Oxazolidinone (linezolid) (14.5%), teicoplanin (13.8%), tigecycline (10.5%) and first-generation cephalosporins (1.3%).Conclusions: Carbapenems showed maximum sensitivity for all urine isolates. The second and third options were polymyxin B and phosphonic acid derivatives, respectively.

scholarly journals Antibiotic Sensitivity Pattern and Plasmid Profile Of Urinary Tract Infection Isolates among Children Below 10 Years Of Age

2019 ◽  
Vol 5 (1) ◽  
pp. 58-62
Author(s):  
Ram Wagle ◽  
Rajendra Timilsina ◽  
Rojesh Thapa ◽  
Nabaraj Adhikari ◽  
Upendra Thapa Shrestha ◽  
...  
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Antibiotic Sensitivity ◽  
Plasmid Profile ◽  
Plasmid Copy ◽  
Lower Urinary Tract Infection ◽  
Cross Sectional ◽  
E Coli ◽  
Sensitivity Pattern

Urinary tract infection (UTI) is defined as colonization of pathogen anywhere along the urinary tract. UTI has been classified by site of infection as Upper urinary tract infection and lower urinary tract infection and by severity as Complicated and uncomplicated UTI. This community based cross sectional study was conducted to determine the Antibiotic sensitivity pattern and plasmid profile of most prevalent urinary tract infection isolates among children below 10 years of age, from December 2013 to February 2014. Among the total 800 sample collected from the community 390(48.8%) were female and 410(51.2%) were male. The prevalence rate was found to be 44(5.5%) of total cases and was statistically significant (p<0.05). Among significant growth, 15(1.9%) and 29(3.6%) were male and female respectively (p<0.05). Out of 44 total isolates frequency of Escherichia coli (E. coli) was 20 followed by Staphylococcus aureus(12), which accounted for 45.5% and 27.3% respectively. Remaining were Pseudomonas(11.4%), Klebsiella(11.4%), Proteus(2.3%)and Citrobacter sps.(2.3%). Tobramycin(100%) and Amikacin(97.73%) were found to be the most sensitive antibiotics followed by Chloramphenicol(93.18%), Imipenem(90.91%) and Ciprofloxacin(75%) respectively.Out of 20 E. coli isolates, no plasmid was seen in 7(35%) while 8(40%) showed single plasmid which was present in 8 isolates. Plasmid copy number of 2, 3 and 4 were displayed by 2(10%), 2(10%) and 1(5%) of the isolates respectively. A common (>21 kilobases) plasmid was the most common among isolates under study. This study revealed that E. coli was the most prevalent organism causing community acquired pediatric UTI. Antibiotics that are commonly used for the management of UTI and other cases are being more resistant i.e., Ampicillin. Plasmid analysis showed the presence of plasmids in resistant E. coli isolates that might harbor resistant genes. So that further analysis is required for the detection of responsible genes. Key words: Antibiotic sensitivity pattern, Plasmid profile, Urinary tract infection

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