scholarly journals Quality of Life After Definitive Linear Accelerator-based Stereotactic Radiotherapy for Prostate Cancer: a Longitudinal Study

2021 ◽  
Author(s):  
Hideomi Yamashita ◽  
Mami Ogita ◽  
Subaru Sawayanagi ◽  
Yuki Nozawa ◽  
Osamu Abe
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Performance Status ◽  
World Health ◽  
Trial Outcome Index ◽  
Adenocarcinoma Of The Prostate ◽  
Localized Disease ◽  
Outcome Index ◽  
Health Organization

Abstract Background: Prostate cancer is the second most common malignancy worldwide, and the majority of patients are diagnosed with localized disease. We examined patients’ quality of life after stereotactic body radiation therapy (SBRT) for prostate cancer. Method: We included patients who were treated between 2016 and 2020. Inclusion criteria were adenocarcinoma of the prostate; class risk of low, intermediate, and high; and a World Health Organization performance status of 0–2. Quality of life was measured using the Functional Assessment of Cancer Therapy-Prostate (FACT-P). Results: A total of 439 patients were treated with SBRT, with a median age of 73 years old. The median follow-up period was 34 months. FACT-P Trial Outcome Index (p < 0.0001), FACT-General (p = 0.0003), and FACT-P-Total (p < 0.0001) scores declined at 1 month post-SBRT, then recovered and returned to the same level as before treatment at 3–4 months post-SBRT. The decrease in quality of life in the first month was particularly remarkable in patients who received long-term hormone injections (36%). One month after the end of SBRT, about 22% of patients experienced "quite a bit” or more troubling side effects. Conclusions: This study showed longitudinal changes in quality of life by FACT-P after SBRT for prostate cancer. Overall, prostate SBRT was well tolerated.

scholarly journals Quality of Life After Definitive Linac Stereotactic Radiotherapy for Prostate Cancer: Longitudinal Study

2021 ◽  
Author(s):  
Hideomi Yamashita ◽  
Mami Ogita ◽  
Subaru Sawayanagi ◽  
Yuki Nozawa ◽  
Osamu Abe
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Performance Status ◽  
Adenocarcinoma Of The Prostate ◽  
Localized Disease ◽  
Total P ◽  
Common Malignancy

Abstract Prostate cancer represents the second most common malignancy in the world and majority of patients have diagnosis of localized disease. We examined quality of life after stereotactic body radiation therapy (SBRT) for prostate cancer. We included patients treated between 2016 and 2020. Inclusion criteria were: adenocarcinoma of the prostate; class risks low, intermediate, and high; WHO performance status 0-2. QoL was measured using the Functional Assessment of Cancer Therapy - Prostate (FACT-P). 439 patients were included, treated with SBRT. Median age was 73. Median follow-up was 34 months. FACT P-TOI (p < 0.0001), FACT G Total (p = 0.0003), and FACT P-total (p < 0.0001) declined at 1 month after the last SBRT, then recovered, and returned to the same level as before treatment at 3-4 month. The decrease in QoL at the first month was particularly remarkable in patients who received long-term hormone injections (36% patients). One month after the end of SBRT, about 22% patients were "quite a bit” or more in trouble with any side effect. We showed the longitudinal changes of quality of life by FACT-P after SBRT for prostate cancer. Prostate SBRT appears to be overall well tolerated.

scholarly journals Five-year quality of life assessment after carbon ion radiotherapy for prostate cancer

2017 ◽  
Vol 58 (2) ◽  
pp. 260-266 ◽  
Author(s):  
Katsuya Maruyama ◽  
Hiroshi Tsuji ◽  
Takuma Nomiya ◽  
Hiroyuki Katoh ◽  
Hitoshi Ishikawa ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Life Assessment ◽  
Carbon Ion Radiotherapy ◽  
Carbon Ion ◽  
Trial Outcome Index ◽  
Related Quality ◽  
Health Related ◽  
Outcome Index

Abstract The aim of this study was to prospectively assess 5-year health-related quality of life (HRQOL) of patients treated with carbon ion radiotherapy (C-ion RT) for clinically localized prostate cancer. A total of 417 patients received carbon ion radiotherapy at a total dose of 63–66 Gray-equivalents (GyE) in 20 fractions over 5 weeks, and neoadjuvant and adjuvant androgen deprivation therapy (ADT) were administered for intermediate and high-risk patients. A HRQOL assessment was performed at five time points (immediately before the initiation of C-ion RT, immediately after, and at 12, 36 and 60 months after completion of C-ion RT) using Functional Assessment of Cancer Therapy (FACT) questionnaires. FACT-G and FACT-P scores were significantly decreased; however, the absolute change after 60 months was minimal. The transient decreases in the Trial Outcome Index (TOI) score returned to their baseline levels. Use of ADT, presence of adverse events, and biochemical failure were related to lower scores. Scores of subdomains of FACT instruments indicated characteristic changes. The pattern of HRQOL change after C-ion RT was similar to that of other modalities. Further controlled studies focusing on a HRQOL in patients with prostate cancer are warranted.

Alexithyme Patientenmerkmale und Lebensqualität – Eine Querschnittsstudie an 79 ambulanten Patienten mit Angststörungen

2013 ◽  
Vol 61 (1) ◽  
pp. 17-26 ◽  
Author(s):  
Katrin Leenen ◽  
Michael Rufer ◽  
Hanspeter Moergeli ◽  
Hans-Jörgen Grabe ◽  
Josef Jenewein ◽  
...  
Keyword(s):  
Quality Of Life ◽  
World Health ◽  
Life Questionnaire ◽  
World Health Organization Quality ◽  
Fand Sich ◽  
Quality Of Life Questionnaire ◽  
Organization Quality ◽  
Health Organization ◽  
Tas 20

Aus Untersuchungen in der Normalbevölkerung ist bekannt, dass Menschen mit erhöhten Alexithymiewerten eine verminderte Lebensqualität (LQ) aufweisen. Für Patienten mit psychischen Störungen wurde dieser Zusammenhang jedoch kaum untersucht. Ziel dieser Studie war es, den möglichen Zusammenhang zwischen alexithymen Patientenmerkmalen und der LQ bei Patienten mit Angststörungen zu überprüfen. Bei 79 ambulanten Patienten mit Angststörungen wurden alexithyme Charakteristika mit der Toronto Alexithymia Scale (TAS-20), die LQ mit der Kurzversion des World Health Organization Quality of Life Questionnaire 100 (WHOQOL-BREF) erfasst. Darüber hinaus fand eine Erhebung der psychischen Symptombelastung (SCL-90-R) und depressiven Symptomatik (MADRS) statt. Mittels hierarchischer Regressionsanalysen wurde der Zusammenhang zwischen der alexithymen Charakteristika und den unterschiedlichen LQ-Domänen berechnet. Die Patienten zeigten eine im Vergleich zur Normalbevölkerung deutlich verminderte LQ. Als Hauptergebnis fand sich, auch nach Kontrolle von Depression, Ängstlichkeit und Geschlecht, ein signifikanter Zusammenhang zwischen den beiden TAS-20 Subskalen Schwierigkeiten, Gefühle zu identifizieren und zu beschreiben und vor allem der psychischen LQ. Unsere Ergebnisse sprechen dafür, bei der Diagnostik und Therapieplanung von Patienten mit Angststörungen alexithyme Merkmale einzubeziehen. Im Falle von ausgeprägten alexithymen Merkmalen sollten psychotherapeutische Interventionen zur Verbesserung der Schwierigkeiten Gefühle wahrzunehmen und zu kommunizieren in Betracht gezogen werden.

scholarly journals Quality of life in patients with narcolepsy: a WHOQOL-bref study

2008 ◽  
Vol 66 (2a) ◽  
pp. 163-167 ◽  
Author(s):  
Heloísa Rovere ◽  
Sueli Rossini ◽  
Rubens Reimão
Keyword(s):  
Quality Of Life ◽  
Patient Group ◽  
World Health ◽  
Control Group ◽  
World Health Organization Quality ◽  
Severe Impairment ◽  
Perception Of Quality ◽  
Social Domains ◽  
Health Organization

OBJECTIVE: To evaluate the perception of Quality of Life (QL) in Brazilian patients with narcolepsy. METHOD: 40 adult patients aged between 20 and 72 years (mean=41.55; SD=14.50); (28 F; 12M), with the diagnosis of chronic narcolepsy were followed up at the outpatient clinic (Patient Group). The Control Group was composed of 40 adults. The instrument utilized was the World Health Organization Quality of Life (WHOQOL-BREF). RESULTS: The two groups were homogeneous and no difference was found with regards to age, sex, and demographic characteristics. The perception of QL in physical, psychological and social domains showed lower scores in those patients with narcolepsy than in the control group (p<0.05). Concerning physical domain, all the aspects evaluated were significantly impaired, in patient group, including sleep satisfaction (p<0.001); energy for daily activities (p=0.039); capacity to perform activities (p=0.001); and capacity to work (p=0.001). CONCLUSION: The perception of QL showed severe impairment in patients with narcolepsy for physical, psychological and social domains.

scholarly journals Implicações do uso do Aparelho de Amplificação Sonora Individual na qualidade de vida de idosos

CoDAS ◽  
2017 ◽  
Vol 29 (5) ◽  
Author(s):  
Camila Zorzetto Carniel ◽  
Juliana Cristina Ferreira de Sousa ◽  
Carla Dias da Silva ◽  
Carla Aparecida de Urzedo Fortunato-Queiroz ◽  
Miguel Ângelo Hyppolito ◽  
...  
Keyword(s):  
Quality Of Life ◽  
World Health Organization ◽  
The Elderly ◽  
World Health ◽  
World Health Organization Quality ◽  
Hearing Handicap ◽  
Organization Quality ◽  
Health Organization ◽  
Post Hoc

RESUMO Objetivo Avaliar, por meio de questionários padronizados, a qualidade de vida de idosos com deficiência auditiva diagnosticada que utilizam ou não a prótese auditiva (AASI) e de idosos sem queixa auditiva. Método Trata-se de um estudo transversal, com amostra não probabilística, distribuída em três grupos divididos da seguinte forma: 30 idosos com perda auditiva diagnosticada e com indicação para uso do aparelho de amplificação sonora individual (AASI), mas que ainda não faziam uso da prótese; 30 idosos com deficiência auditiva que usavam o AASI; e 30 idosos sem queixa auditiva. Os participantes completaram um questionário que investigava dados sociodemográficos e familiares, o Hearing Handicap Inventory for the Elderly Screening Version (HHIE-S) e o World Health Organization Quality of Life - versão breve (WHOQOL-Breve). Além das análises descritivas dos dados, foram realizados testes para comparação dos três grupos, aplicando-se a análise de variância (ANOVA) e o teste post hoc de Bonferroni. Resultados Os três grupos se diferenciaram significativamente em todos os domínios de qualidade de vida. O grupo de idosos com perda auditiva diagnosticada e com indicação para uso do AASI apresentou menores escores que o grupo de idosos com deficiência auditiva que usavam o AASI e que o grupo de referência. O grupo com AASI apresentou os melhores resultados de qualidade de vida. Conclusão A perda auditiva afeta a qualidade de vida do idoso. O uso efetivo da prótese auditiva é benéfico a esta população, melhorando suas condições de vida e saúde.

scholarly journals Magnesium level correlation with clinical status and quality of life in women with hormone related conditions and pregnancy based on real world data

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Svetlana Orlova ◽  
Galina Dikke ◽  
Gisele Pickering ◽  
Eliso Djobava ◽  
Sofya Konchits ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Clinical Status ◽  
High Response Rate ◽  
World Health ◽  
Life Questionnaire ◽  
Real World Data ◽  
World Health Organization Quality ◽  
Patient Reported ◽  
Health Organization

AbstractThis study was aimed to assess the effectiveness of magnesium (Mg)-vitamin B 6 replenishment and its correlation with clinical status in pregnant women (PW), and quality of life in women with hormone-related conditions (HRCW) and hypomagnesemia (HME). Data collected in four observational studies were pooled and analysed. All women received Mg supplementation for 4 weeks. The proportion of women with normalized Mg level, and the correlation between serum Mg dynamics and number of symptoms/complaints (PW) or changes in World Health Organization quality of life questionnaire scores (WHOQOL; HRCW) were evaluated. 869 PW and 957 HRCW were included in the study. Normalization of serum Mg level to ≥ 0.66 mmol/L occurred in 92.1% of PW and 78.4% of HRCW, and to ≥ 0.8 mmol/L in 73.8% and 58.9%, respectively. Mg normalization was accompanied by a median decrease of 1 symptom and 1 complaint in PW. Serum Mg level increase by 0.1 mmol/L was associated to significant changes in the WHOQOL scores in HRCW. Treatment of HME with the Mg for approximately 4 weeks provided a high response rate of Mg serum level, was associated with an improvement in symptom severity and complaints in PW, and WHOQOL score in HRCW. A 0.8 mmol/L cut-off appeared to be more relevant in terms of patient-reported outcomes.

Pelatihan Regulasi Emosi untuk Meningkatkan Kualitas Hidup Caregiver Skizofrenia

2021 ◽  
Vol 5 (1) ◽  
pp. 39-51
Author(s):  
Anisa Fitriani ◽  
Fuad Nashori ◽  
Indahria Sulistyarini
Keyword(s):  
Quality Of Life ◽  
World Health Organization ◽  
World Health ◽  
Control Group ◽  
Control Group Design ◽  
Purposive Sampling ◽  
Group Design ◽  
Health Organization

Penelitian ini bertujuan untuk mengetahui pengaruh pelatihan regulasi emosi untuk meningkatkan kualitas hidup caregiver skizofrenia. Metode yang digunakan adalah kuasi eksperimen dengan pretest-posttest control group design dan teknik pengambilan sampel menggunakan purposive sampling. Subjek terdiri atas dua puluh caregiver laki-laki dan perempuan berusia 47-63 tahun yang dibagi dalam kelompok eksperimen dan kontrol. Metode pengumpulan data menggunakan wawancara, observasi, dan pengukuran kualtias hidup dengan skala World Health Organization of Quality of Life-BREF. Data dianalisis menggunakan anava campuran untuk mengetahui perbedaan kualitas hidup kelompok eksperimen dan kontrol saat prates, paskates, dan tindak lanjut. Hasil penelitian menunjukkan adanya peningkatan yang sangat signifikan pada skor kualitas hidup kelompok eksperimen setelah diberi pelatihan regulasi emosi. Skor kualitas hidup mengalami peningkatan kembali saat pengukuran tindak lanjut, sedangkan pada kelompok kontrol tidak terdapat peningkatan yang signifikan. Hasil tersebut menunjukkan bahwa pelatihan regulasi emosi efektif dalam meningkatkan kualitas hidup caregiver skizofrenia.

scholarly journals Qualidade de vida, cognição e desempenho nas funções executivas de idosos

2012 ◽  
Vol 29 (2) ◽  
pp. 155-162 ◽  
Author(s):  
Michele Beckert ◽  
Tatiana Quarti Irigaray ◽  
Clarissa Marceli Trentini
Keyword(s):  
Quality Of Life ◽  
World Health Organization ◽  
World Health ◽  
World Health Organization Quality ◽  
Organization Quality ◽  
Health Organization

A relação entre qualidade de vida e funções cognitivas em idosos tem sido pouco estudada. O objetivo deste estudo foi examinar a associação entre qualidade de vida, cognição e desempenho nas funções executivas de idosos. O estudo teve a participação de 88 idosos. Utilizou-se o método amostral de conveniência. Todos os participantes responderam sobre condições sociodemográficas, qualidade de vida (World Health Organization Quality of Life Group-Bref), funções cognitivas (Mini-Exame do Estado Mental e Instrumento de Avaliação Neuropsicológica Breve) e funções executivas (Teste Wisconsin de Classificação de Cartas). Os dados mostraram associações importantes entre os domínios de qualidade de vida Físico e Meio Ambiente e variáveis cognitivas, o que reforça a importância da cognição tanto na manutenção de cuidados físicos, quanto nas oportunidades de o idoso adquirir novas informações e habilidades no meio em que vive.

scholarly journals Avaliação da qualidade de vida em pacientes laringectomizados: uma revisão sistemática

2002 ◽  
Vol 18 (1) ◽  
pp. 81-92 ◽  
Author(s):  
Arlinda B. Moreno ◽  
Claudia S. Lopes
Keyword(s):  
Quality Of Life ◽  
World Health Organization ◽  
World Health ◽  
World Health Organization Quality ◽  
Organization Quality ◽  
Health Organization

Laringectomia é a principal seqüela em pacientes com câncer de laringe. Neste estudo, as autoras conduziram uma revisão sistemática para avaliar a relação entre qualidade de vida e laringectomia. De 96 artigos publicados em periódicos científicos, previamente identificados, foram selecionados 35 artigos sobre laringectomia e qualidade de vida em pacientes laringectomizados. Todos os artigos selecionados foram submetidos à abordagem metodológica de uma revisão sistemática. Para a avaliação dos atributos qualitativos dos artigos foi utilizado o Questionário de Avaliação Qualitativa (QAQ), um instrumento testado e validado. Os resultados encontrados mostraram que a maior parte dos artigos selecionados apresentava inconsistências e falta de rigor metodológico na mensuração do constructo qualidade de vida entre pacientes laringectomizados. Além disso, verificou-se que a relação entre qualidade de vida e laringectomia, na forma apresentada nos artigos selecionados, ainda se encontra distante da abordagem multidimensional do constructo qualidade de vida, conforme preconizado pelo WHOQOL (World Health Organization - Quality of Life Group).

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