Racial and Geographical Disparities in Colorectal Cancer Incidence in Mississippi, 2003-2018

Mapping Intimacies ◽

10.21203/rs.3.rs-1054671/v1 ◽

2021 ◽

Author(s):

Sasha McKay ◽

Jaymie Meliker

Keyword(s):

Colorectal Cancer ◽

Racial Disparities ◽

Incidence Rate ◽

Cancer Incidence ◽

Incidence Rates ◽

The State ◽

Cold Spot ◽

Incidence Data ◽

Effective Interventions ◽

Colorectal Cancer Incidence

Abstract Purpose: The aim of this study is to investigate racial and geographical disparities of colorectal cancer incidence in Mississippi. Methods: Incidence data from 2003-2018 were obtained at the county-level from the Mississippi Cancer Registry. Incidence rate difference and 95% confidence intervals between age-adjusted colorectal cancer incidence for whites and blacks were calculated and mapped using ArcGIS. Results: The black incidence rate for colorectal cancer was 59.8 per 100,000 while the white incidence rate was 48.9 per 100,000. Blacks experienced significantly higher incidence rates than whites in 39 counties throughout much of Mississippi. These areas of higher racial disparities did not cluster in a specific region of the state. In the southern part of the state an 8-county cold-spot region was detected without racial disparities; incidence rate for blacks was 41.3 per 100,000 in this region. Conclusions: There are racial disparities throughout Mississippi except for an 8-county region towards the southern part of the state. Additional research should be conducted to identify what factors are responsible for the lower incidence rates among blacks in this region, and to implement effective interventions statewide to reduce racial disparities in colorectal cancer incidence.

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Are temporal trends in colonoscopy among young adults concordant with colorectal cancer incidence?

Journal of Medical Screening ◽

10.1177/0969141319859608 ◽

2019 ◽

Vol 26 (4) ◽

pp. 179-185 ◽

Cited By ~ 10

Author(s):

Stacey A Fedewa ◽

Rebecca L Siegel ◽

Ahmedin Jemal

Keyword(s):

Colorectal Cancer ◽

Incidence Rate ◽

Cancer Incidence ◽

Rate Ratio ◽

Incidence Rate Ratio ◽

Population Based ◽

Incidence Rates ◽

Age Group ◽

Colorectal Cancer Incidence ◽

Cancer Incidence Rates

Objective In the United States, colorectal cancer incidence has increased in adults under age 55. Although debate remains about whether this rise is a result of increased detection because of more colonoscopy utilization, population-based trends in colonoscopy among this age group are unknown. We examined changes in colonoscopy rates, as well as colorectal cancer incidence, among adults aged 40–54, using nationally representative data. Methods Recent (past year) colonoscopy rates were computed among 53,175 respondents aged 40–54 in National Health Interview Survey data from 2000 through 2015 by five-year age group. Colorectal cancer incidence rates and incidence rate ratios were estimated from 18 population-based Surveillance Epidemiology and End Result registries during the same period. Results Among respondents aged 40–44, past-year colonoscopy rates were stable during 2000–2015, and ranged from 2.3% to 3.5% ( p-value for trend = 0.771). In contrast, colonoscopy rates increased from 2.5% in 2000 to 5.2% in 2015 among ages 45–49, and from 5.0% to 14.1% in ages 50–54 (test for trend p-values < 0.001). During 2000–2015, colorectal cancer incidence rates increased by 28% in people aged 40–44 (incidence rate ratio = 1.28, 95% CI 1.20, 2.37), 15% in those aged 45–49 (incidence rate ratio = 1.15, 95%CI 1.10, 1.21), and 17% in those aged 50–54 (incidence rate ratio = 1.17, 95%CI 1.13, 1.21), respectively. Conclusion Increases in colonoscopy rates were confined to ages 45–54, whereas colorectal cancer incidence rates rose in those aged 40–44, 45–49, and 50–54. Colonoscopy trends do not fully align with colorectal cancer incidence patterns.

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Colorectal Cancer in Lebanon: Incidence, Temporal Trends, and Comparison to Regional and Western Countries

Cancer Control ◽

10.1177/1073274821996869 ◽

2021 ◽

Vol 28 ◽

pp. 107327482199686

Author(s):

Najla A. Lakkis ◽

Ola El-Kibbi ◽

Mona H. Osman

Keyword(s):

Colorectal Cancer ◽

Cancer Incidence ◽

Temporal Trends ◽

Incidence Rates ◽

Steady Increase ◽

P Value ◽

Western Countries ◽

Incidence And Mortality ◽

Colorectal Cancer Incidence ◽

Males And Females

Global trends in the incidence and mortality rates of colorectal cancer show a steady increase with significant predilection to western developed countries, possibly linking it to westernized lifestyles among other risk factors. This study aims to investigate the incidence and trends of colorectal cancer in Lebanon, a country in the Middle East and North Africa region, and to compare these rates to those in regional and western countries. Colorectal cancer incidence data were extracted from the Lebanese National Cancer Registry for the currently available years 2005 to 2016. The calculated age-standardized incidence rates and age-specific rates were expressed as per 100,000 population. The age-standardized incidence rates of colorectal cancer in Lebanon increased from 16.3 and 13.0 per 100,000 in 2005 to 23.2 and 20.2 per 100,000 in 2016, among males and females, respectively. The incidences were higher for males, and they increased with age. The annual percent change was +4.36% and +4.45%, in males and females respectively (p-value < 0.05). There was a non-statistically significant trend of decrease in recent years (since 2012 in males and since 2011 in females). The age-standardized incidence rates in Lebanon were higher than those in the majority of the regional countries, but lower than the rates in developed western countries. There were high age-specific incidence rates at age groups 40-44 and 45-49 years in Lebanon in both males and females (with significant rising temporal trend) compared to other countries, including the ones reported to have the highest colorectal cancer age-standardized incidence rate worldwide. Therefore, the burden of colorectal cancer is significant in Lebanon. This raises the necessity to develop national strategies tailored to reduce colorectal cancer incidence through promoting healthy lifestyles, raising awareness, and early detection as of 40 years of age.

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International Trends in Colorectal Cancer Incidence Rates

Cancer Epidemiology Biomarkers & Prevention ◽

10.1158/1055-9965.epi-09-0090 ◽

2009 ◽

Vol 18 (6) ◽

pp. 1688-1694 ◽

Cited By ~ 492

Author(s):

Melissa M. Center ◽

Ahmedin Jemal ◽

Elizabeth Ward

Keyword(s):

Colorectal Cancer ◽

Cancer Incidence ◽

Incidence Rates ◽

International Trends ◽

Colorectal Cancer Incidence ◽

Cancer Incidence Rates

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Colorectal Cancer in Young and Older Adults in Uruguay: Changes in Recent Incidence and Mortality Trends

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18158232 ◽

2021 ◽

Vol 18 (15) ◽

pp. 8232

Author(s):

Carina Musetti ◽

Mariela Garau ◽

Rafael Alonso ◽

Marion Piñeros ◽

Isabelle Soerjomataram ◽

...

Keyword(s):

Colorectal Cancer ◽

Older Adults ◽

Cancer Incidence ◽

Age Groups ◽

Incidence Rates ◽

Mortality Trends ◽

Screening Programs ◽

Lifestyle Risk Factors ◽

Incidence And Mortality ◽

Colorectal Cancer Incidence

Uruguay has the highest colorectal cancer incidence rates in Latin America. Previous studies reported a stable incidence and a slight increase in mortality among males. We aimed to assess colorectal cancer incidence (2002–2017) and mortality trends (1990–2017) by age groups and sex, using data from the National Cancer Registry. Annual percent changes (APCs) were estimated using joinpoint regression models. We included 27,561 colorectal cancer cases and 25,403 deaths. We found an increasing incidence among both males and females aged 40–49, with annual increases of 3.1% (95%CI: 1.21–5.03) and 2.1% (95%CI: 0.49–3.66), respectively, and an increasein the rate in older males (70+) of 0.60% (95%CI: 0.02–1.20) per year between 2002 and 2017. Mortality remained stable among those younger than 50, whereas it decreased for older females aged 50–69 and 70+ (APC: −0.61% (−1.07–0.14) and −0.68% (−1.02–0.34), respectively), and increased for the oldest males (70+; APC: 0.74 (0.47–1.01)). In conclusion, we found rising colorectal cancer incidence accompanied by stable mortality in young adults. Sex disparities were also found among the older adults, with a more favorable pattern for females. Exposures to dietary and lifestyle risk factors, and inequalities in access to and awareness of screening programs, are probably among the main underlying causes and deserve further investigation.

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