scholarly journals May hepatic steatosis be associated with gynecomastia and epicardial fat? A retrospective study of 599 male patients

Author(s):  
Suleyman Hilmi Aksoy ◽  
Selami Aydin ◽  
Isil Yurdaisik ◽  
Orhan Dalkilic

Abstract Objective There is no study in the literature investigating the association of hepatic steatosis with both gynecomastia and epicardial fat thickness together. We aimed to determine the correlations between hepatic steatosis through liver density, gynecomastia and epicardial fat thickness in patients undergoing CT scans due to suspected COVID-19 symptoms. Methods A total of 599 male patients who underwent chest CT scans due to a presumed diagnosis of COVID-19 in our radiology clinic were included in the study. Patients’ age, diameters of the subareolar glandular tissues of the right and left breasts, the right retroareolar fatty tissue, liver and spleen density, epicardial fat thickness and biochemical parameters were recorded and analyzed. The laboratory analyses were performed according to the standard methods. Results The mean age of the patients was 47.21±15.00 years. The left subareolar tissue thickness and the right retroareolar fatty tissue thickness that are used to indicate the presence of gynecomastia were found to be significantly correlated with liver density in negative direction (r=-.137, p<0.001; r=-.172, p<0.001; respectively). Epicardial fat thickness was statistically significantly correlated with right subareolar tissue thickness (r=.085, p=0.037), left subareolar tissue thickness (r=.101, p=0.014) and right retroareolar fatty tissue thickness (r=.148, p<0.001). Conclusion The results of this study showed that gynecomastia was significantly correlated with both age and hepatic steatosis. Epicardial fat thickness was also associated with liver steatosis. We demonstrated the significant correlations between epicardial fat thickness and gynecomastia for the first time. Nevertheless, our results need to be confirmed by further comprehensive studies.

2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
In Kyoung Shim ◽  
Kyoung-Im Cho ◽  
Hyun-Su Kim ◽  
Jung-Ho Heo ◽  
Tae Joon Cha

This study aimed to investigate the effects of gender on the association between epicardial fat thickness (EFT) and circadian blood pressure (BP) changes in patients with recently diagnosed essential hypertension (EH). A total of 441 patients with EH (male/female: 236/205, mean age: 50.7 ± 13.8) and 83 control patients underwent 24-hour ambulatory BP monitoring and echocardiography. Obese EH patients had higher circadian BP profile with BP variability, wall thickness, and left ventricular mass than nonobese EH patients and controls (allp’s<0.05) without gender differences. EFT was higher in female than in male patients (7.0 ± 2.5 versus 5.9 ± 2.2 mm,p<0.001) and higher in the obese female EH group (7.5 ± 2.6 mm) than in the control (6.4 ± 2.8 mm) or nonobese EH group (6.7 ± 2.8 mm) among women, whereas EFT did not vary among males (5.9 ± 1.9 versus 6.0 ± 2.7 versus 5.9 ± 2.4 mm,p=0.937). Multivariate logistic regression analysis demonstrated that the 24-hour mean BP variability was associated with SBP (p=0.018) and EFT (p=0.016) in female patients, but not in male patients. The relationships among circadian BP variability, obesity, and EFT were affected by gender in different manners. EFT may be a more valuable parameter in the evaluation of BP severity and obesity in women than in men.


Author(s):  
M.M. Vela-Huerta ◽  
N. Amador-Licona ◽  
R. Domínguez-Damiá ◽  
A. Heredia-Ruiz ◽  
H.V. Orozco-Villagomez ◽  
...  

BACKGROUND: Epicardial fat thickness (EFT) in adults and children has been related to the metabolic syndrome and other cardiovascular risk factors; however, scarce studies have evaluated it in infants of diabetic mothers (IDM) in whom, alterations in the thickness of the interventricular septum have been reported. This study compares the EFT in IDM versus infants of non-diabetic mothers (INDM) and its association with others echocardiographic parameters. METHODS: We performed a cross sectional study in 93 infants (64 IDM and 29 INDM). To evaluate EFT dimensions, an echocardiogram was performed within the first 24h of extrauterine life in both groups. In diabetic mothers, HbA1c was also determined. RESULTS: There was no significant difference in birth weight between the groups although gestational age was lower in IDM. The EFT (3.6 vs. 2.5 mm, p <  0.0001), the interventricular septum thickness (IVST) (6.2 vs. 5.2 mm, p <  0.0001) and the IVST / left ventricle posterior wall (1.3 vs. 1.1, p = 0.001) were higher in the IDM; while the left ventricular expulsion fraction [LVFE] (71.1 vs. 77.8; p <  0.0001) was lower than in the INDM, respectively. We found a positive correlation between EFT with IVST (r = 0.577; p = 0.0001), LVPW (r = 0.262; p = 0.011), IVST/LVPW index (r = 0.353; p = 0.001), and mitral integral early velocity (r = 0.313; p = 0.002), while a negative correlation with LVFE was observed (r = –0.376; p = 0.0001). CONCLUSIONS: The EFT is higher in IDM than in INDM. It was positively related with echocardiographic parameters of left ventricular thickness and negatively with left ventricular ejection function.


2014 ◽  
Vol 32 (5) ◽  
pp. 740-748 ◽  
Author(s):  
Mehmet Mustafa Tabakci ◽  
Halil İbrahim Durmuş ◽  
Anil Avci ◽  
Cuneyt Toprak ◽  
Serdar Demir ◽  
...  

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