scholarly journals Honey Bee Venom Re-Challenge During Specific Immunotherapy: Prolonged Cardio-Pulmonary Resuscitation Allowed Survival in a Case of Near Fatal Anaphylaxis

2021 ◽  
Author(s):  
Sara Micaletto ◽  
Kurt Ruetzler ◽  
Martin Bruesch ◽  
Peter Schmid-Grendelmeier
Keyword(s):  
Honey Bee ◽  
Specific Immunotherapy ◽  
Time Span ◽  
Bee Venom ◽  
Bee Sting ◽  
Cardio Pulmonary Resuscitation ◽  
Risk Patients ◽  
Cardio Vascular ◽  
Sting Challenge ◽  
Fatal Anaphylaxis

Abstract BACKGROUND Specific immunotherapy for patients with honey bee hypersensitivity is commonly applied. Re-challenge with venom is performed to prove protection.CASE PRESENATION We report a case of near fatal anaphylaxis with asystolia for 24 minutes in a 35-years-old patient with mastocytosis after honey bee sting challenge despite 5-years of specific immunotherapy. Successful cardio-pulmonary resuscitation (CPR) was applied for 32 minutes.CONCLUSION This intervention demonstrates, that in anaphylaxis with cardio-vascular arrest prolonged CPR for up to 40 minutes might be appropriate to overcome half time span of massively released histamine. Failure of specific immunotherapy was possibly due to sensitization to the allergen Api m10, probably underrepresented in commercial honey bee venom extracts. Also, molecular analyses might alert to potential unsuccessful outcome of venom specific immunotherapy especially in high-risk patients such as mastocytosis.

Expression and Function of C5a Receptor in a Fatal Anaphylaxis After Honey Bee Sting*

2011 ◽  
Vol 56 (2) ◽  
pp. 526-528 ◽  
Author(s):  
Klára Törő ◽  
Katalin Borka ◽  
Magdolna Kardos ◽  
István Kristóf ◽  
Péter Sótonyi
Keyword(s):  
Honey Bee ◽  
C5a Receptor ◽  
Bee Sting ◽  
And Function ◽  
Fatal Anaphylaxis

scholarly journals Beehive Products as Antibacterial Agents: A Review

Antibiotics ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 717
Author(s):  
Rita Abou Nader ◽  
Rawan Mackieh ◽  
Rim Wehbe ◽  
Dany El El Obeid ◽  
Jean Marc Sabatier ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Honey Bee ◽  
Antibacterial Agents ◽  
Royal Jelly ◽  
Biological Activities ◽  
Vital Role ◽  
Bee Venom ◽  
Bacterial Strains ◽  
Wide Range ◽  
Life Threatening

Honeybees are one of the most marvelous and economically beneficial insects. As pollinators, they play a vital role in every aspect of the ecosystem. Beehive products have been used for thousands of years in many cultures for the treatment of various diseases. Their healing properties have been documented in many religious texts like the Noble Quran and the Holy Bible. Honey, bee venom, propolis, pollen and royal jelly all demonstrated a richness in their bioactive compounds which make them effective against a variety of bacterial strains. Furthermore, many studies showed that honey and bee venom work as powerful antibacterial agents against a wide range of bacteria including life-threatening bacteria. Several reports documented the biological activities of honeybee products but none of them emphasized on the antibacterial activity of all beehive products. Therefore, this review aims to highlight the antibacterial activity of honey, bee venom, propolis, pollen and royal jelly, that are produced by honeybees.

41. Anti-Inflammatory Effect of Honey Bee Venom on Wistar Rats Induced Poly Cystic Ovarian Syndrome by Estradiol Valerate

Toxicon ◽  
2012 ◽  
Vol 60 (2) ◽  
pp. 115-116
Author(s):  
Mohammad Nabiuni ◽  
Kazem Parivar ◽  
Bahman Zeynali ◽  
Azar Sheikholeslami ◽  
Latifeh Karimzadeh
Keyword(s):  
Honey Bee ◽  
Wistar Rats ◽  
Bee Venom ◽  
Estradiol Valerate ◽  
Anti Inflammatory ◽  
Ovarian Syndrome ◽  
Inflammatory Effect

scholarly journals Anti-mutagenic and synergistic cytotoxic effect of cisplatin and Honey Bee venom on 4T1 invasive mammary carcinoma cell line

2017 ◽  
Author(s):  
Faranak Shiassi Arani ◽  
Latifeh Karimzadeh ◽  
Seyed Mohammad Ghafoori ◽  
Mohammad Nabiuni
Keyword(s):  
Cell Death ◽  
Cell Line ◽  
Honey Bee ◽  
Mtt Assay ◽  
Sodium Azide ◽  
Mammary Carcinoma ◽  
Ames Test ◽  
Cytotoxic Effect ◽  
Mutagenic Activity ◽  
Bee Venom

ABSTRACTHoney Bee Venom has various biological activities such as inhibitory effect on several types of cancer. Cisplatin is an old and potent drug to treat the most of cancer. Our aims in this study were determination of the anti-mutagenic and cytotoxic effects of HBV on mammary carcinoma, lonely and in combination with cisplatin. In this study 4T1 cell line were cultured and incubated at 37 C in humidified CO2-incubator. The cell viabilities were examined by MTT assay. Also HBV was screened for its anti-mutagenic activity against sodium azide by Ames test. The result showed that 6μg/ml HBV, 20μg/ml cisplatin and 6μg/ml HBV with 10μg/ml cisplatin can induce an approximately 50% 4T1 cell death. 7mg/ml HBV with the inhibition of 62.76% sodium azide showed high potential in decreasing the mutagenic agents. MTT assay demonstrated that HBV and cisplatin can cause cell death in a dose-dependent manner. The cytotoxic effect of cisplatin is also promoted by HBV. Ames test results indicated that HBV can inhibit sodium azide as a mutagenic agent. Anti-mutagenic activity of HBV was increased significantly in presence of S9 mix. Hence, our findings reveal that HBV can enhance the cytotoxic effect of cisplatin drug and it has cancer preventing effects.

scholarly journals A RARE CASE OF HEMIPLEGIA

2020 ◽  
pp. 30-30
Author(s):  
Valeti Rajeswari ◽  
Kolluru V D Karthik ◽  
Srinivasula Sriranga Pravallika
Keyword(s):  
Cerebral Infarction ◽  
Honey Bee ◽  
Anaphylactic Shock ◽  
Rare Case ◽  
The Body ◽  
Intravenous Fluids ◽  
Rare Entity ◽  
Bee Sting ◽  
The Face

Honey bee sting induced Cerebral infarction is a rare entity . We report a case of 55year old male presented with anaphylactic shock following honey bee sting along with weakness of left side of the body and the face . He was managed with anti histaminics, adrenaline injections, Intravenous fluids , vasopressors , anti platelets and anticoagulants .

scholarly journals Morphology of the Dufour gland within the honey bee sting gland complex

Apidologie ◽  
2005 ◽  
Vol 36 (4) ◽  
pp. 543-546 ◽  
Author(s):  
Stephen J. Martin ◽  
Vicky Dils ◽  
Johan Billen
Keyword(s):  
Honey Bee ◽  
Dufour Gland ◽  
Bee Sting
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