scholarly journals Giant Pleomorphic Lipoma With Malignant Transformation in the Buttock: a Rare Case Report and Literature Review

Author(s):  
Feng Liang ◽  
Xu Wang ◽  
Guangmeng Xu ◽  
Hongyu He ◽  
Wei Li ◽  
...  

Abstract Background: Pleomorphic lipoma is a benign tumor, which is often located in the neck, shoulder, and other subcutaneous tissues. Pleomorphic lipoma with malignant transformation in the buttock is rarely reported.Case Presentation: A 53-year-old male attended to our department with a large mass in his buttock that had been present for about one year, leading to difficulty with walking and defecation. Computed tomography (CT) showed a 10. 2 × 8. 3 cm mass with lumpy and mixed low to medium density shadows in the right side of the lower part of the tailbone. Color Doppler ultrasound showed that the skin and subcutaneous tissues of the right buttock were thickened with lymphedema. Pre-operative pathology revealed a large amount of adipose and fusiform fibrous tissues with obvious blood vessels. The patient underwent complete resection of the mass in the right buttock. Postoperative pathology indicated that the tumor was pleomorphic lipoma with malignant transformation. The patient recovered well and was discharged from the hospital at day 12 post-surgery. Follow up at 6 months did not find any symptoms of tumor recurrence.Conclusions: Pleomorphic lipoma with malignant transformation is rare. CT, magnetic resonance imaging (MRI) and histopathology are the main methods used to diagnose pleomorphic lipoma. Complete resection of the tumor is vital to treat giant pleomorphic lipoma successfully.

2021 ◽  
Vol 27 ◽  
pp. 107602962110305
Author(s):  
Pu Ying ◽  
Wenge Ding ◽  
Xiaowei Jiang ◽  
Yue Xu ◽  
Yi Xue ◽  
...  

We evaluated the risk factors of deep venous thrombosis (DVT) after knee arthroscopic posterior cruciate ligament (PCL) reconstruction in patients with only PCL injury. From August 2014 to December 2020, a total of 172 patients who had accepted knee arthroscopic PCL reconstruction underwent the color Doppler ultrasound of bilateral lower-extremities deep veins on 3 days postoperatively. Based on the inspection results, patients were divided into DVT group (18 males and 8 females, mean age 43.62 years) and non-DVT group (108 males and 38 females, mean age 33.96 years). The potential associations of DVT risk and age, gender, body mass index (BMI), diabetes, hypertension, smoking and other factors were analyzed. An old age (OR = 1.090; 95% CI = 1.025-1.158; P = 0.006), a high BMI (OR = 1.509; 95% CI = 1.181-1.929; P = 0.001) and an increased post-surgery D-dimer (OR = 5.034; 95% CI = 2.091-12,117; P ≤ 0.001) value were significantly associated with an elevated DVT risk after knee arthroscopic PCL reconstruction. Increased age, BMI, and postoperative D-dimer were risk factors of DVT following knee arthroscopic PCL reconstruction in patients with only PCL injury.


2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Shiho Nagayama ◽  
Hironori Takahashi ◽  
Shohei Tozawa ◽  
Risa Narumi ◽  
Rie Usui ◽  
...  

An interstitial pregnancy that continues beyond the second trimester is a rare phenomenon. We report a patient with an interstitial pregnancy undiagnosed until the third trimester. A multiparous woman was referred to us because of preeclampsia at 26 weeks of gestation. The placental position was the right fundus, and color Doppler ultrasound revealed myometrial thinning and subplacental hypervascularity, leading to a suspicion of placenta accreta spectrum (PAS). Emergency cesarean section was performed at 281/7 weeks of gestation due to severe preeclampsia. The right tubal horn to the isthmus of the fallopian tube bulged with placental adhesion and a part of the tube had ruptured, with the omentum adhering to the ruptured part. Interstitial and tubal isthmic pregnancy with uterine rupture was diagnosed.


2020 ◽  
Author(s):  
Dai Xiaoyu ◽  
Ding Wenge ◽  
Li Huan ◽  
Peng Xu ◽  
Wang Kejie ◽  
...  

Abstract Background To analyse the common risk factors of deep venous thrombosis (DVT) after knee arthroscopic posterior cruciate ligament (PCL) reconstruction in patients with PCL injury. Methods From August 2014 to December 2019, a total of 86 patients who had accepted knee arthroscopic PCL reconstruction underwent the color Doppler ultrasound of bilateral lower-extremities deep veins on 3 days postoperatively. Based on the inspection results, patients were divided into DVT group (9 males and 4 females, mean age 43.62 years) and non-DVT group (54 males and 19 females, mean age 33.96 years). The potential associations of DVT risk and age, gender, body mass index (BMI), diabetes, hypertension, smoking and other factors were analysed. Results High BMI and post-surgery D-dimer values were significantly associated with DVT risk. Conclusions Increased BMI and postoperative D-dimer levels are risk factors of DVT following knee arthroscopic PCL reconstruction in patients with PCL injury.


2019 ◽  
Vol 9 (2) ◽  
pp. 371-375
Author(s):  
Zhiyong Chen ◽  
Binshan Zha ◽  
Yan Li ◽  
Yongchao Chen

Objective: There is a great controversy about whether the internal jugular vein (IJV) should be retained during radical neck dissection. In this study, the right and left IJV under different body position were observed by color Doppler ultrasound, in order to provide a experimental basis for the preservation of IJV in neck dissections. Methods: A total of 40 patients with thyroid cancer undergoing radical neck dissection were examined in this study. The hemodynamic data such as section area, velocity, and volume of blood flow were measured by Doppler in supine and sitting position under quiet breath. Results: In supine position, the cross sectional area, the velocity and the blood flow volume in the right side were 58%, 23% and 91% more than left side respectively. The right side advantage, symmetrical, and left side advantage of IJV was in 65%, 25%, and 10% of patients. The blood flow of bilateral IJV was 74% of total cerebral outflow. The IJV predominate, balanced type, and no-IJV predominate cerebral venous drainage was in 73%, 23% and 5% of patients. In sitting position, the section area, the velocity and the blood flow volume in the right side were 29%, 35% and 56% more than left side respectively. The right side advantage, symmetrical, and left side advantage of IJV was in 45%, 45%, and 10% of patients. The blood flow of bilateral IJV was 23% of total cerebral outflow. The balanced type and no-IJV predominate cerebral venous drainage was in 23% and 78% of patients. Conclusions: There are side advantage of IJV. With quiet breathing, IJV is not the main pathway of cerebral venous drainage in sitting position. The preoperative ultrasound is useful to design the individualized surgical approach for the radical neck dissections.


2019 ◽  
Vol 8 (3) ◽  
Author(s):  
Seyhan Yılmaz ◽  
Sabür Zengin ◽  
Fatma Gürgen ◽  
Feryaz Kızıltan

Superficial venous aneurysms, which are mostly asymptomatic and detected when patients were referred to for the treatment or evaluation of a femoral or inguinal hernia or soft tissue masses, are associated with a risk of developing pulmonary embolism. We aimed to present a case of a greater saphenous vein aneurysm of which its misdiagnosis possesses morbidity risk and confused with inguinal hernia. A 45- year-old female patient admitted to our clinic with swelling and pain in her right groin that had been present for about three years. The patient was also treated with inguinal hernia repair once due to her related complaints. A venous color doppler ultrasound was performed for differential diagnosis and a 70x31-mm sized fusiform proximal greater saphenous vein aneurysm and a grade-4 pathologic reflux in the right saphenofemoral junction was observed in the ultrasonographic examination. As a result, the swelling detected in the inguinal region should be evaluated in terms of possible superficial venous aneurysm, which may cause thromboembolism and ruptures, and this condition, which is frequently confused with inguinal hernia, should be taken into consideration and taken under operation as soon as possible in case of its presence.


2012 ◽  
Vol 2012 ◽  
pp. 1-3
Author(s):  
Claudia Bruè ◽  
Cesare Mariotti ◽  
Edoardo De Franco ◽  
Nicola De Franco ◽  
Alfonso Giovannini

Vitreous cysts are very rare ocular malformations. In this observational case study, we report on an unusual case of a pigmented free-floating vitreous cyst and discuss its differential diagnosis. A 14-year-old male was referred to ophthalmology for a pigmented lesion in his left eye. He complained of an intermittent floater in the left eye. Visual acuity was 20/20 in the right eye and 20/40 in the left eye. Fundus examination was unremarkable bilaterally, except for a piece of brownish oval material floating in the vitreous in the left eye. He had received a knock on the left side of his head a few days before the visual discomfort of the left eye. Real-time ultrasound of the left eye detected a piece of hyperechogenic spherical material with no internal reflectivity, floating in the middle of the vitreous. The first use of color Doppler ultrasound in this context indicated no arterial flow, ruling out the presence of a persistent hyaloid artery. Intraocular cysts are rare ocular disorders, which have been divided into clear and pigmented cysts, and into those that occupy the anterior chamber, the retrolental space, and the vitreous cavity. This last is extremely rare. We describe such a case.


2021 ◽  
Author(s):  
Dai Xiaoyu ◽  
Ying Pu ◽  
Xu Peng ◽  
Huang Zhihui ◽  
Li Huan ◽  
...  

Abstract Background: The factors leading to venous thromboembolism (VTE) have been known for a long time. Previous data has suggested a potential link between erythrocyte aggregation (EA) and deep vein thrombosis (DVT). Considering a relatively large number of patients who need total knee arthroplasty (TKA) surgery due to primary knee osteoarthritis (KOA), this study is tried to verify whether preoperative EA may have an effect on postoperative DVT after TKA in these patients.Methods: A total of 750 KOA patients accepted unilateral TKA were enrolled from March 2010 to May 2020. On the third day after surgery, they all accepted the color Doppler ultrasound examination of both legs for deep veins and were subsequently divided into DVT and non-DVT groups. We made a thorough analysis to demonstrate the specific association of EA exponent before TKA and DVT risk after TKA.Results: Low EA exponent was a significant risk factor for DVT in patients with primary KOA (p<0.05), especially in females after stratifying by gender (p<0.05). Conclusions: Our results suggested that low EA before TKA was substantially associated with a high post-surgery DVT risk in primary KOA patients. Timely and effective anticoagulant therapy for such patients was required.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Jun Zhou ◽  
Meng-xing Lv ◽  
Ling Duan ◽  
Yu-cheng Xie ◽  
Zhi-xiang A ◽  
...  

Abstract Background Malignant melanoma (MM) arises predominantly after adolescence and is uncommon in children. Congenital MM in newborns is even rarer with a dearth of published literature; as a consequence, there is no uniform standard for the pathogenesis and treatment for neonatal malignant melanoma. Herein we report a case of giant congenital nodular MM in a newborn, including its clinical, imaging, pathological and molecular pathological features. This case is the largest giant congenital primary nodular malignant melanoma in utero in neonates currently reported in China. Case presentation A female neonatal patient was found to have a 2.97 cm× 1.82 cm×1.50 cm mass with a clear boundary at the right acromion in color Doppler ultrasound examination at 24 weeks of gestation. The mass increased to 3.0 cm×5.0 cm×9.0 cm at birth, and local ulceration was seen. MRI demonstrated that the mass was located on the right shoulder and underarm in a lobulated appearance, and surrounded the right scapula which was deformed. Clinical stage:IV(AJCC 8th Edition (2017)). α-Fetoprofein (AFP) by hematological examination: 1210ng/ml, NSE: 21.28ng/ml, LDH: 842U/L. The patient underwent surgical resection of the tumor, and was pathologically diagnosed as neonatal congenital malignant melanoma; immunohistochemistry (IHC): S-100 (+), HMB45 (+), Melan A (+), and Tyrosinase (+). Molecular pathological examination for BRAF V600E showed no mutations (Quantitative Real-time PCR, qPCR); And so were NRAS, C-kit (exons 9,11,13,14,17,18), and TERT (promoter locus, C228T and C250T) (Sanger sequencing). Non-surgical therapies were not carried out after the surgical resection of the tumor. After 6 months of follow-up, the child developed normally, and color Doppler ultrasound showed no obvious tumor growth or abnormality in the original tumor site. Conclusions It is extremely rare to see giant congenital primary nodular MM in utero in neonates. The pathogenesis, treatment and prognosis of congenital MM need further research. The diagnosis mainly depends on histopathology and immunohistochemistry, and it needs to be differentiated from malignant lymphoma and primitive neuroectodermal tumor. The current treatment strategy for MM relies on the surgical excision of the mass. Research directed at molecular detection for genetic mutations would contribute to targeted therapy and better prognosis.


Neurosurgery ◽  
2004 ◽  
Vol 55 (1) ◽  
pp. 155-161 ◽  
Author(s):  
Robert J. Dempsey ◽  
Roham Moftakhar ◽  
Myron Pozniak

Abstract OBJECTIVE: Intraoperative color Doppler ultrasound has been used to locate arteriovenous malformations (AVMs). We describe the use of spectral Doppler to measure flow resistance and resistive index (RI) of vessels around the nidus to distinguish feeding arteries from en passant and normal vessels. This is particularly helpful in small AVMs and aids in the identification of normal vessels and completeness of resection by ruling out persistent low RI flow. METHODS: Seven patients with AVMs underwent resection. Spectral Doppler applied to the vessels in proximity to the AVM, along with calculated RI, was used to identify feeding arteries and draining veins. After presumed surgical resection of the AVM, pre-resection and postresection RIs were compared to identify residual AVM. Postoperative angiography was performed in all seven patients to confirm complete resection of the AVM. RESULTS: The mean pre-resection RI of vessels feeding the AVM was 0.34 (±0.01). In five patients without residual nidus on the basis of postresection color Doppler and postoperative angiogram, the postresection RI was 0.62 (±0.04). In two patients, the postresection scan identified a nidus with persistent low RI flow. Once residual AVM was resected, the RI became significantly higher. A postoperative angiogram confirmed complete resection of the AVM in all patients. CONCLUSION: Intraoperative duplex Doppler allowed more accurate localization of the AVM nidus. RI of the vessels around the AVM helped to distinguish vessels feeding the AVM from en passant vessels. Furthermore, comparison of pre-resection and postresection RI accurately indicated the completeness of resection.


2013 ◽  
Vol 19 (3) ◽  
pp. 353-358 ◽  
Author(s):  
Ammar Taha ◽  
Ellen K Walsh ◽  
Kathryn A Wright ◽  
Iftikhar Ahmed ◽  
Nucharin Supakul ◽  
...  

This retrospective study evaluated the safety and feasibility of a new arterial femoral access closure device in neurointerventional procedures. The study includes all consecutive adult patients who underwent femoral arteriotomy closure with the MynxGrip™ closure device after Neurointerventional procedures performed between June and December 2012. All patients had a follow-up color Doppler ultrasound (US) within 48 hours after the procedure, which was independently interpreted by two experienced radiologists to evaluate for access site complications. Device success/failure, sheath size, ambulation time, and periprocedural complications were recorded. Fifty-five closure devices were deployed in 53 patients. There were 23 (43%) males and 30 (57%) females; age ranged from 22 to 84 years (mean: 52.1 years). Thirty of the 55 procedures (55%) were therapeutic and 25 were diagnostic interventions (45%). Sheath sizes used were 5F in 35 procedures (64%) and 6F in 20 procedures (36%). The right femoral artery was accessed in 51 procedures (93%) and the left in four procedures (7%). There was only one (1.8%) minor periprocedural complication (small hematoma). Hemostasis was successful in 51 of the 55 procedures (93%) with subsequent early ambulation. No device-induced complications associated with serious clinical sequelae were reported. In our small series, the MynxGrip™ femoral access closure device provided a safe and feasible way of closing the femoral artery puncture site after neurointerventional procedures with low minor complication rates and no major complications. Further large prospective randomized trials are necessary to evaluate the efficacy of the device.


Sign in / Sign up

Export Citation Format

Share Document