Outcome following Percutaneous Trans-hepatic Biliary Drainage (PTBD) in carcinoma gallbladder: A prospective observational study

Abstract Introduction: Percutaneous Biliary drainage (PTBD) is required as palliation and optimization for surgery or chemotherapy in carcinoma gallbladder (GBC) but may be associated with complications. We aimed to study the outcomes, complications and changes in quality of life in patients with GBC undergoing PTBD. Methods: A prospective study from July 2018 to December 2019 in patients of GBC presenting with obstructive jaundice was done. Patients planned for PTBD were included in the study. The progression of disease, complications of PTBD, re-interventions, effects on initiation or completion of chemotherapy, surgical resection or intervention, overall survival was recorded. Quality of life (QoL) was assessed using SF–36 questionnaire before and after 4-6 weeks of intervention. Results: Of 160 patients assessed for inclusion, 60 (mean age: 53.7 ± 10.95 years, 27 (45 %) males) were eventually included. Eleven patients (18.3%) had metastatic disease at presentation. Of 60 patients undergoing PTBD, none had immediate procedure related complications, 41(68 %) patients had at-least one and 18 (30%) patients had more than one complication. The most common complication was peri-catheter bile leak (41.6%) followed by catheter dislodgement (30 %), blockage (23.3 %) and bleeding (10 %). Re-intervention was required in 32 (53 %) of patients. There was a significant decrease in QoL after PTBD (P<0.0001). Median survival after PTBD was 12 weeks.Conclusion: The high technical success of PTBD does not translate into the improvement of QoL, survival, and curative surgical treatment.

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Quality of life following surgery for large and giant vestibular schwannomas: a prospective study

Journal of Neurosurgery ◽

10.3171/2014.10.jns14534 ◽

2015 ◽

Vol 122 (2) ◽

pp. 303-311 ◽

Cited By ~ 12

Author(s):

Mazda K. Turel ◽

Sumit Thakar ◽

Vedantam Rajshekhar

Keyword(s):

Quality Of Life ◽

Short Form ◽

Minimum Clinically Important Difference ◽

Glasgow Benefit Inventory ◽

Sf 36 ◽

Before And After ◽

Health Related Qol ◽

A Prospective Study

OBJECT Prospective studies of quality of life (QOL) are infrequently performed in patients undergoing surgery for vestibular schwannoma (VS). The authors designed this to study to investigate health-related QOL (HR-QOL) in patients with large and giant VSs before and after surgery. METHODS Between January 2009 and December 2012, HR-QOL was measured prospectively before and after surgery, using the 36-Item Short Form Health Survey (SF-36), in 100 patients who underwent surgery for unilateral large or giant VS (tumor size ≥ 3 cm). The Glasgow Benefit Inventory (GBI) was also used to evaluate the effect of surgery. RESULTS A total of 100 patients were included in the study (65 men and 35 women). Their mean age (± SD) was 44.2 ± 11.5 years. The preoperative QOL was decreased in all SF-36 domains. A 1-year follow-up evaluation was conducted for all patients (mean 13.5 ± 5.3 months after surgery). The results showed an improvement in HR-QOL compared with preoperative status in all cases, with 63%–85% of patients showing a minimum clinically important difference (MCID) in various domains. A second follow-up evaluation was performed in 51 cases (mean time after surgery, 29.0 ± 8.3 months) and showed sustained improvement in SF-36 scores. In some domains there was further improvement beyond the first follow-up. On the GBI, 87% of patients reported improvement, 1% felt no change, and 12% of patients reported deterioration. CONCLUSIONS Patients harboring large or giant VSs score lower on all the QOL domains compared with the normative population. More than 60% showed a clinically significant improvement in HR-QOL 1 year after surgery, a result that was sustained at subsequent follow-up.

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Quality of Life Before and After Endovascular and Open Repair of Asymptomatic AAAs: A Prospective Study

Journal of Endovascular Therapy ◽

10.1583/1545-1550(2000)007<0372:qolbaa>2.0.co;2 ◽

2000 ◽

Vol 7 (5) ◽

pp. 372-379 ◽

Cited By ~ 17

Author(s):

Martin Malina ◽

Marie Nilsson ◽

Jan Brunkwall ◽

Krasnodar Ivancev ◽

Timothy Resch ◽

...

Keyword(s):

Quality Of Life ◽

Prospective Study ◽

Open Repair ◽

Before And After ◽

A Prospective Study

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The sensitivity to change of the cluster headache quality of life scale assessed before and after deep brain stimulation of the ventral tegmental area

The Journal of Headache and Pain ◽

10.1186/s10194-021-01251-5 ◽

2021 ◽

Vol 22 (1) ◽

Author(s):

Davide Cappon ◽

Agata Ryterska ◽

Harith Akram ◽

Susie Lagrata ◽

Sanjay Cheema ◽

...

Keyword(s):

Quality Of Life ◽

Cluster Headache ◽

Mcgill Pain Questionnaire ◽

Sensitivity To Change ◽

Sf 36 ◽

Quality Of Life Scale ◽

Before And After ◽

Life Scale ◽

Generic Measures

Abstract Background Cluster headache (CH) is a trigeminal autonomic cephalalgia (TAC) characterized by a highly disabling headache that negatively impacts quality of life and causes limitations in daily functioning as well as social functioning and family life. Since specific measures to assess the quality of life (QoL) in TACs are lacking, we recently developed and validated the cluster headache quality of life scale (CH-QoL). The sensitivity of CH-QoL to change after a medical intervention has not been evaluated yet. Methods This study aimed to test the sensitivity to change of the CH-QoL in CH. Specifically we aimed to (i) assess the sensitivity of CH-QoL to change before and following deep brain stimulation of the ventral tegmental area (VTA-DBS), (ii) evaluate the relationship of changes on CH-QoL with changes in other generic measures of quality of life, as well as indices of mood and pain. Ten consecutive CH patients completed the CH-QoL and underwent neuropsychological assessment before and after VTA-DBS. The patients were evaluated on headache frequency, severity, and load (HAL) as well as on tests of generic quality of life (Short Form-36 (SF-36)), mood (Beck Depression Inventory, Hospital Anxiety and Depression Rating Scale), and pain (McGill Pain Questionnaire, Headache Impact Test, Pain Behaviour Checklist). Results The CH-QoL total score was significantly reduced after compared to before VTA-DBS. Changes in the CH-QoL total score correlated significantly and negatively with changes in HAL, the SF-36, and positively and significantly with depression and the evaluative domain on the McGill Pain Questionnaire. Conclusions Our findings demonstrate that changes after VTA-DBS in CH-QoL total scores are associated with the reduction of frequency, duration, and severity of headache attacks after surgery. Moreover, post VTA-DBS improvement in CH-QoL scores is associated with an amelioration in quality of life assessed with generic measures, a reduction of depressive symptoms, and evaluative pain experience after VTA-DBS. These results support the sensitivity to change of the CH-QoL and further demonstrate the validity and applicability of CH-QoL as a disease specific measure of quality of life for CH.

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A functional electric orthesis on the paretic leg improves quality of life of stroke patients

Arquivos de Neuro-Psiquiatria ◽

10.1590/s0004-282x2006000100005 ◽

2006 ◽

Vol 64 (1) ◽

pp. 20-23 ◽

Cited By ~ 9

Author(s):

Mara Renata Fernandes ◽

Luciane B.C. Carvalho ◽

Gilmar F. Prado

Keyword(s):

Quality Of Life ◽

Social Functioning ◽

Physical Functioning ◽

Bodily Pain ◽

Improve Quality ◽

Stroke Patients ◽

Normal Life ◽

Sf 36 ◽

Before And After

CONTEXT: Hemiparesia changes quality of life of patients with stroke making difficult a normal life. OBJECTIVE: To evaluate the effect of Functional Eletric Orthesis (FEO) applied over the paretic leg in the quality of life of stroke patients. METHOD: The quality of life of 50 stroke patients of Associacao de Assistencia a Crianca Deficiente (AACD) was evaluated with SF-36 questionnaire before and after the treatment with a FEO for rehabilitation of walking. We analyzed data according to gender and affected hemisphere. RESULTS: The average values from all domains of SF-36 improved significantly (p<0.001). Female patients improved more than male in Emotional Domain (p=0.04) and presented a trend to be better regarding Bodily Pain and Social Functioning. Patients with right hemiparesia improved more than those with left hemiparesia (p=0.02). CONCLUSION: FEO over a paretic leg is efficient to improve quality of life of stroke patients, mainly Physical Functioning.

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The effects of breathing exercises on respiratory functions, functional capacity and quality of life in vehicle spray painters

International Journal of Therapy and Rehabilitation ◽

10.12968/ijtr.2021.0092 ◽

2021 ◽

Vol 28 (12) ◽

pp. 1-8

Author(s):

Burak Yilmaz ◽

Cagtay Maden ◽

Begümhan Turhan

Keyword(s):

Quality Of Life ◽

Functional Capacity ◽

Control Group ◽

Study Group ◽

Breathing Exercises ◽

Sf 36 ◽

Significant Difference ◽

Before And After ◽

Respiratory Exercises

Background/aims Workers engaged in vehicle spray painting are at a risk of developing respiratory problems because of the solvents in the spray paints. Changes in respiratory functions and functional capacities caused by spray painting can be improved with respiratory exercises. The aim of this study was to examine the effects of respiratory exercises on the respiratory functions, functional capacity and quality of life in vehicle spray painters. Methods A total of 70 volunteers with similar characteristics participated in the study. The groups were divided into two groups randomly (35 study group, 35 control group). Respiratory functions (value of forced expiratory volume percentage in 1 second [FEV1]), forced vital capacity percentage [FVC], FEV1/FVC percentage, peak expiratory flow percentage [PEF (%)] and maximum voluntary ventilation percentage [MVV (%)]), functional capacity (6-Minute Walk Test) and quality of life (Short Form Health Survey [SF-36]) were evaluated. The study group undertook supervised breathing exercises 3 days a week for 6 weeks. The same exercises were given to the control group as a home programme. Home programmes were followed up by telephone calls. Evaluations were performed again after 6 weeks. Results In the study group, FEV1 (%) increased more than in the control group (P<0.05). The increase in PEF (%) was similar in both groups (P>0.05). In the study group, FEV1/FVC (%) and MVV (%) were significantly different before and after the intervention (P<0.05), but there was no difference in the control group (P>0.05). There was a greater increase in the study group than in the control group (P<0.05). 6-Minute Walk Test distance (m) before and after the intervention in both groups were similar (P>0.05). Before and after the intervention, a significant difference was found in the vitality and the social function domains of the SF-36 in the study group. In the comparisons of groups, a significant difference was found in the study group in the role-emotional, social function and bodily pain domains of the SF-36 after the intervention (P<0.05). Conclusions Breathing exercises can be recommended for vehicle spray painters to avoid an increase in respiratory resistance and to improve their quality of life.

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Health-related quality of life using QOLIE-31: Before and after epilepsy surgery a prospective study at a tertiary care center

Neurology India ◽

10.4103/0028-3886.37093 ◽

2007 ◽

Vol 55 (4) ◽

pp. 343 ◽

Cited By ~ 11

Author(s):

PoodipediSarat Chandra ◽

FaizUddin Ahmad ◽

Manjari Tripathi ◽

MV Padma ◽

Shailesh Gaikwad ◽

...

Keyword(s):

Quality Of Life ◽

Care Center ◽

Tertiary Care ◽

Tertiary Care Center ◽

Health Related Quality ◽

Before And After ◽

Related Quality ◽

Health Related ◽

A Prospective Study

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THE EFFECT OF URINARY INCONTINENCE AND VOIDING DYSFUNCTION ON QUALITY OF LIFE BEFORE AND AFTER RADICAL RETRO PUBIC PROSTATECTOMY – RESULTS OF A PROSPECTIVE STUDY

European Urology Supplements ◽

10.1016/s1569-9056(08)60687-9 ◽

2008 ◽

Vol 7 (3) ◽

pp. 243

Author(s):

M. Musch ◽

U. Roggenbuck ◽

M. Mosters ◽

V. Klevecka ◽

D. Kroepfl

Keyword(s):

Quality Of Life ◽

Urinary Incontinence ◽

Prospective Study ◽

Voiding Dysfunction ◽

Before And After ◽

A Prospective Study

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Quality of life and vaginal symptoms of postmenopausal women using pessary for pelvic organ prolapse: a prospective study

Revista da Associação Médica Brasileira ◽

10.1590/1806-9282.64.12.1103 ◽

2018 ◽

Vol 64 (12) ◽

pp. 1103-1107 ◽

Cited By ~ 2

Author(s):

Suelene C. Albuquerque Coelho ◽

Marcos Marangoni-Junior ◽

Luiz Gustavo Oliveira Brito ◽

Edilson Benedito de Castro ◽

Cássia Raquel Teatin Juliato

Keyword(s):

Quality Of Life ◽

Pelvic Organ Prolapse ◽

Pelvic Organ ◽

Urinary Symptoms ◽

Pelvic Surgery ◽

Subjective Impression ◽

Vaginal Symptoms ◽

Sf 36 ◽

A Prospective Study

SUMMARY OBJECTIVE: The use of pessary is an option for the conservative treatment of pelvic organ prolapse (POP). However, here are few studies assess the quality of life (QoL) after inserting the pessary for POP. We have hypothesized that the use of pessary would modify QoL in women with POP. METHODS: A prospective, observational study was performed that included 19 women with advanced POP. Pessary was introduced, and the SF-36 (general quality of life) and ICIQ-VS (vaginal symptoms and quality of life subdomain) questionnaires were applied before the introduction and after six months. A single question about the satisfaction regarding the use of the device was presented (subjective impression). RESULTS: The mean age of the women included was 76 years. Most of them were non-caucasian (52.6%), with no prior pelvic surgery (57.5%), with urinary symptoms (78.9%). A third of the patients reported sexual activity. After treatment, 22.2% of them presented vaginal infection, and 27.7% increased vaginal discharge. Urinary symptoms remained unaltered. Women reported 100% satisfaction after using the pessary (77.7% partial improvement; 22.3% total improvement). SF-36 had significant improvement in three specific domains: general state of health (p=0.090), vitality (p=0.0497) and social aspects (p=0.007). ICIQ-VS presented a reduction in the vaginal symptoms (p < 0.0001) and an improvement in QoL (P < 0.0001). CONCLUSION: The use of pessary for six months improved the QoL and reduced vaginal symptoms for women with advanced POP.

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