scholarly journals Molecular epidemiology and risk factors of Stenotrophomonas maltophilia infections in a Chinese teaching hospital

2020 ◽  
Author(s):  
Zhongliang Duan ◽  
Juanxiu Qin ◽  
Yao Liu ◽  
Cui Li ◽  
Chunmei Ying
Keyword(s):  
Risk Factors ◽  
Teaching Hospital ◽  
Stenotrophomonas Maltophilia ◽  
Age Groups ◽  
Epidemiological Data ◽  
Resistance Rate ◽  
Control Group ◽  
Molecular Characteristics ◽  
Significant Difference ◽  
Chinese Teaching

Abstract Background: Stenotrophomonas maltophilia (S. maltophilia) is an important opportunistic pathogen that can be isolated in hospitals. With the abuse of broad spectrum antibiotics and invasive surgical devices, the rate of S. maltophilia infection is increasing every year. This study was an epidemiological analysis of the clinical and molecular characteristics of S. maltophilia infection in a Chinese teaching hospital. The goal was to obtain a comprehensive understanding of the status of S. maltophilia infection to provide strong epidemiological data for the prevention and treatment of S. maltophilia infection.Results: A total of 93 isolates from Renji Hospital affiliated with the Shanghai Jiaotong University School of Medicine were included, in which 62 isolates were from male patients. In addition, 81 isolates were isolated from sputum samples. A total of 86 patients had underlying diseases. All patients received antibiotics. Multilocus sequence typing (MLST) analysis indicated that 61 different sequence types (STs) were found (including 45 novel STs), and MLST did not show significantly dominant STs. Pulsed field gel electrophoresis (PFGE) results showed that 93 isolates could be divided into 73 clusters, and they also showed weak genetic linkages between isolates. The resistant rates to trimethoprim/sulfamethoxazole (TMP/SMX) and levofloxacin were 9.7% and 4.3%, respectively, and all isolates were susceptible to minocycline. Four virulence gene’s loci Stmpr1, Stmpr2, Smf-1, and Smlt3773 were positive in 79.6%, 91.4%, 94.6%, and 52.7% of the isolates, respectively. Three biofilm genes rmlA, spgM, and rpfF were positive in 82.8%, 92.5%, and 64.5% of the isolates, respectively. Mean biofilm forming level of OD492 was 0.54 ± 0.49. We did not find any significant difference between different genders and different age-groups. We retrospectively analyzed data from patients in the intensive care unit (ICU) and the control group. The independent risk factors of those who were infected in the ICU included immunosuppression and the increased antibiotic usage.Conclusions: Most of the patients had prior medical usage histories and baseline diseases. The positive rate of virulence genes was high, the drug resistance rate of S. maltophilia was low, and the biofilm formation ability was strong. The increased use of antibiotics was an independent risk factor for S. maltophilia infection, which should receive more attention. No obvious clonal transmissions were found in the same departments.

scholarly journals Molecular epidemiology and risk factors of Stenotrophomonas maltophilia infections in a Chinese teaching hospital

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Zhongliang Duan ◽  
Juanxiu Qin ◽  
Yao Liu ◽  
Cui Li ◽  
Chunmei Ying
Keyword(s):  
Risk Factors ◽  
Teaching Hospital ◽  
Stenotrophomonas Maltophilia ◽  
Age Groups ◽  
Epidemiological Data ◽  
Resistance Rate ◽  
Control Group ◽  
Molecular Characteristics ◽  
Significant Difference ◽  
Chinese Teaching

Abstract Background Stenotrophomonas maltophilia (S. maltophilia) is an important opportunistic pathogen that can be isolated in hospitals. With the abuse of broad spectrum antibiotics and invasive surgical devices, the rate of S. maltophilia infection is increasing every year. This study was an epidemiological analysis of the clinical and molecular characteristics of S. maltophilia infection in a Chinese teaching hospital. The goal was to obtain a comprehensive understanding of the status of S. maltophilia infection to provide strong epidemiological data for the prevention and treatment of S. maltophilia infection. Results A total of 93 isolates from Renji Hospital affiliated with the Shanghai Jiaotong University School of Medicine were included, in which 62 isolates were from male patients. In addition, 81 isolates were isolated from sputum samples. A total of 86 patients had underlying diseases. All patients received antibiotics. Multilocus sequence typing (MLST) analysis indicated that 61 different sequence types (STs) were found (including 45 novel STs), and MLST did not show significantly dominant STs. Pulsed field gel electrophoresis (PFGE) results showed that 93 isolates could be divided into 73 clusters, and they also showed weak genetic linkages between isolates. The resistant rates to trimethoprim/sulfamethoxazole (TMP/SMX) and levofloxacin were 9.7 and 4.3%, respectively, and all isolates were susceptible to minocycline. Four virulence gene’s loci Stmpr1, Stmpr2, Smf-1, and Smlt3773 were positive in 79.6, 91.4, 94.6, and 52.7% of the isolates, respectively. Three biofilm genes rmlA, spgM, and rpfF were positive in 82.8, 92.5, and 64.5% of the isolates, respectively. Mean biofilm forming level of OD492 was 0.54 ± 0.49. We did not find any significant difference between different genders and different age-groups. We retrospectively analyzed data from patients in the intensive care unit (ICU) and the control group. The independent risk factors of those who were infected in the ICU included immunosuppression and the increased antibiotic usage. Conclusions Most of the patients had prior medical usage histories and baseline diseases. The positive rate of virulence genes was high, the drug resistance rate of S. maltophilia was low, and the biofilm formation ability was strong. The increased use of antibiotics was an independent risk factor for S. maltophilia infection, which should receive more attention. No obvious clonal transmissions were found in the same departments.

scholarly journals Molecular epidemiology and risk factors of Stenotrophomonas maltophilia infections in a Chinese teaching hospital

2020 ◽  
Author(s):  
Zhongliang Duan ◽  
Juanxiu Qin ◽  
Yao Liu ◽  
Cui Li ◽  
Chunmei Ying
Keyword(s):  
Risk Factors ◽  
Teaching Hospital ◽  
Stenotrophomonas Maltophilia ◽  
Age Groups ◽  
Epidemiological Data ◽  
Resistance Rate ◽  
Control Group ◽  
Molecular Characteristics ◽  
Significant Difference ◽  
Chinese Teaching

Abstract Background: Stenotrophomonas maltophilia (S. maltophilia) is an important opportunistic pathogen that can be isolated in hospitals. With the abuse of broad spectrum antibiotics and invasive surgical devices, the rate of S. maltophilia infection is increasing every year. This study was an epidemiological analysis of the clinical and molecular characteristics of S. maltophilia infection in a Chinese teaching hospital. The goal was to obtain a comprehensive understanding of the status of S. maltophilia infection to provide strong epidemiological data for the prevention and treatment of S. maltophilia infection.Results: A total of 93 isolates from Renji Hospital affiliated with the Shanghai Jiaotong University School of Medicine were included, in which 62 isolates were from male patients. In addition, 81 isolates were isolated from sputum samples. A total of 86 patients had underlying diseases. All patients received antibiotics. Multilocus sequence typing (MLST) analysis indicated that 61 different sequence types (STs) were found (including 45 novel STs), and MLST did not show significantly dominant STs. Pulsed field gel electrophoresis (PFGE) results showed that 93 isolates could be divided into 73 clusters, and they also showed weak genetic linkages between isolates. The resistant rates to trimethoprim/sulfamethoxazole (TMP/SMX) and levofloxacin were 9.7% and 4.3%, respectively, and all isolates were susceptible to minocycline. Four virulence gene’s loci Stmpr1, Stmpr2, Smf-1, and Smlt3773 were positive in 79.6%, 91.4%, 94.6%, and 52.7% of the isolates, respectively. Three biofilm genes rmlA, spgM, and rpfF were positive in 82.8%, 92.5%, and 64.5% of the isolates, respectively. Mean biofilm forming level of OD492 was 0.54 ± 0.49. We did not find any significant difference between different genders and different age-groups. We retrospectively analyzed data from patients in the intensive care unit (ICU) and the control group. The independent risk factors of those who were infected in the ICU included immunosuppression and the increased antibiotic usage.Conclusions: Most of the patients had prior medical usage histories and baseline diseases. The positive rate of virulence genes was high, the drug resistance rate of S. maltophilia was low, and the biofilm formation ability was strong. The increased use of antibiotics was an independent risk factor for S. maltophilia infection, which should receive more attention. No obvious clonal transmissions were found in the same departments.

scholarly journals Molecular epidemiology and risk factors of Stenotrophomonas maltophilia infections in a Chinese teaching hospital

2020 ◽  
Author(s):  
Zhongliang Duan ◽  
Juanxiu Qin ◽  
Yao Liu ◽  
Cui Li ◽  
Chunmei Ying
Keyword(s):  
Risk Factors ◽  
Teaching Hospital ◽  
Stenotrophomonas Maltophilia ◽  
Virulence Genes ◽  
Age Groups ◽  
Resistance Rate ◽  
Control Group ◽  
Molecular Characteristics ◽  
Significant Difference ◽  
Chinese Teaching

Abstract Background: Stenotrophomonas maltophilia (S. maltophilia) is an important opportunistic pathogen obtained in hospitals. With the abuse of broad spectrum antibiotics and invasive surgical devices, the rate of S. maltophilia infections is increasing year by year. This study is aimed at epidemiological analysis of the clinical and molecular characteristics of S. maltophilia infections in a Chinese teaching hospital. We wish to have a comprehensive understanding of the status of S. maltophilia infections, in order to provide strong epidemiological data for the prevention and treatment of S. maltophilia infections. Results: 93 isolates from the Renji Hospital affiliated to Shanghai Jiaotong University School of Medicine were included, in which 62 strains were from male patients and 81 isolates were cultured from sputum samples. 86 patients had underlying diseases. All patients have received antibiotic therapeutics. MLST analysis indicated that 61 different sequence types (STs) were found (including 45 novel STs), and MLST did not show significantly adominant STs. PFGE showed weak genetic linkage between strains. The resistant rates of Trimethoprim/sulfamethoxazole (TMP/SMX) and levofloxacin were 9.7% and 4.3%. All the strains were susceptible to minocycline. The positive rates of the four virulence genes Stmpr1, Stmpr2, Smf-1 and Smlt3773 locus were 79.6%, 91.4%, 94.6% and 52.7%. The positive rates of the three biofilm genes rmlA, spgM and rpfF were 82.8%, 92.5% and 64.5%. The mean biofilm forming level of OD492 was 0.54 ± 0.49, and there was no significant difference between genders and among different age groups. The data from patients with ICU and the control group were analyzed retrospectively, and the risk factors infected in ICU included the hypoimmunity and the increase of the use of antibiotics were independent risk factors. Conclusion: Most of the patients had prior medical usage history and baseline diseases. The carrying rate of virulence genes was high, the drug resistance rate of S. maltophilia was low, and the biofilm formation ability was strong. The increased use of antibiotics is an independent risk factor for S. maltophilia infection, which should be payed more attention. No obvious clonal transmission was found in the same department.

scholarly journals Molecular epidemiology and risk factors of Stenotrophomonas maltophilia infections in a Chinese teaching hospital

2020 ◽  
Author(s):  
Zhongliang Duan ◽  
Juanxiu Qin ◽  
Yao Liu ◽  
Cui Li ◽  
Chunmei Ying
Keyword(s):  
Risk Factors ◽  
Teaching Hospital ◽  
Stenotrophomonas Maltophilia ◽  
Age Groups ◽  
Epidemiological Data ◽  
Opportunistic Pathogen ◽  
Resistance Rate ◽  
Molecular Characteristics ◽  
Significant Difference ◽  
Chinese Teaching

Abstract Background: Stenotrophomonas maltophilia ( S. maltophilia ) is an important opportunistic pathogen. With the abuse of broad spectrum antibiotics and invasive surgical devices, the rate of S . maltophilia infections is increasing every year. This study is an epidemiological analysis of the clinical and molecular characteristics of S . maltophilia infections in a Chinese teaching hospital, to obtain a comprehensive understanding of S . maltophilia infection to provide strong epidemiological data for the prevention and treatment of S . maltophilia.Results: A total of 93 isolates were included, in which 62 isolates were from male patients and 81 isolates were isolated from sputum samples. A total of 86 patients had underlying diseases. All of the patients had received antibiotic therapeutics. The multilocus sequence typing (MLST) analysis indicated that 61 different sequence types (STs) were found, and the MLST did not show significantly dominant STs. Pulsed field gel electrophoresis (PFGE) results showed the 93 isolates could be divided into 73 clusters, and they also showed weak genetic linkage between isolates. The resistant rates to Trimethoprim/sulfamethoxazole (TMP/SMX) and levofloxacin were 9.7% and 4.3%, respectively, and all of the isolates were susceptible to minocycline. The positive rates of the four virulence genesStmpr1 , Stmpr2 , Smf-1 , and Smlt3773 locus were 79.6%, 91.4%, 94.6%, and 52.7%, respectively. The positive rates of the three biofilm genes rmlA , spgM, and rpfF were 82.8%, 92.5%, and 64.5%, respectively. The mean biofilm forming level of OD 492 was 0.54 ± 0.49, and there was no significant difference between different genders and different age groups. The independent risk factors of those who were infected in the ICU included immunosuppression and the increased of the antibiotics usage.Conclusions: Most of the patients had prior medical usage histories and baseline diseases. The positive rate of virulence genes was high, the drug resistance rate of S . maltophilia was low, and the biofilm formation ability was strong. The increased use of antibiotics was an independent risk factor for S . maltophilia infection, which should receive more attention. No obvious clonal transmission was found in the same department.

scholarly journals Molecular epidemiology and risk factors of Stenotrophomonas maltophilia infections in a Chinese teaching hospital

2020 ◽  
Author(s):  
Zhongliang Duan ◽  
Juanxiu Qin ◽  
Yao Liu ◽  
Cui Li ◽  
Chunmei Ying
Keyword(s):  
Risk Factors ◽  
Teaching Hospital ◽  
Stenotrophomonas Maltophilia ◽  
Virulence Genes ◽  
Age Groups ◽  
Resistance Rate ◽  
Control Group ◽  
Molecular Characteristics ◽  
Significant Difference ◽  
Chinese Teaching

Abstract Background: Stenotrophomonas maltophilia ( S. maltophilia ) is an important opportunistic pathogen obtained in hospitals. With the abuse of broad spectrum antibiotics and invasive surgical devices, the rate of S . maltophilia infections is increasing every year. This study is an epidemiological analysis of the clinical and molecular characteristics of S . maltophilia infections in a Chinese teaching hospital. The goal is to obtain a comprehensive understanding of the status of S . maltophilia infections in order to provide strong epidemiological data for the prevention and treatment of S . maltophilia infections. Results: A total of 93 isolates from the Renji Hospital were included, in which 81 isolates were cultured from sputum samples, and 86 patients had underlying diseases. All of the patients had received antibiotic therapeutics. The multilocus sequence typing (MLST) analysis indicated that 61 different sequence types (STs) were found (including 45 novel STs), and the MLST did not show significantly dominant STs. The resistant rates to Trimethoprim/sulfamethoxazole (TMP/SMX) and levofloxacin were 9.7% and 4.3%. All of the strains were susceptible to minocycline. The positive rates of the four virulence genes Stmpr1 , Stmpr2 , Smf-1 , and Smlt3773 locus were 79.6%, 91.4%, 94.6% and 52.7%, respectively. The positive rates of the three biofilm genes rmlA , spgM, and rpfF were 82.8%, 92.5%, and 64.5%, respectively. The mean biofilm forming level of OD 492 was 0.54 ± 0.49, and there was no significant difference between different genders and age groups. Data from patients in the intensive care unit (ICU) and the control group were analyzed, and the independent risk factors of those who were infected in the ICU included immunosuppression and the increased of the use of antibiotics. Conclusions : Most of the patients had prior medical usage histories and baseline diseases. The carrying rate of virulence genes was high, the drug resistance rate of S . maltophilia was low, and the biofilm formation ability was strong. The increased use of antibiotics was an independent risk factor for S . maltophilia infection, which should receive more attention. No obvious clonal transmission was found in the same department.

scholarly journals Molecular epidemiology and risk factors of Stenotrophomonas maltophilia infections in a Chinese teaching hospital

2020 ◽  
Author(s):  
Zhongliang Duan ◽  
Juanxiu Qin ◽  
Yao Liu ◽  
Cui Li ◽  
Chunmei Ying
Keyword(s):  
Risk Factors ◽  
Teaching Hospital ◽  
Stenotrophomonas Maltophilia ◽  
Virulence Genes ◽  
Age Groups ◽  
Resistance Rate ◽  
Control Group ◽  
Molecular Characteristics ◽  
Significant Difference ◽  
Chinese Teaching

Abstract Background: Stenotrophomonas maltophilia (S. maltophilia) is an important opportunistic pathogen that can be isolated in hospitals. With the abuse of broad spectrum antibiotics and invasive surgical devices, the rate of S. maltophilia infection is increasing every year. This study is an epidemiological analysis of the clinical and molecular characteristics of S. maltophilia infection in a Chinese teaching hospital. The goal is to obtain a comprehensive understanding of the status of S. maltophilia infection in order to provide strong epidemiological data for the prevention and treatment of S. maltophilia infection.Results: A total of 93 isolates from Renji Hospital affiliated to Shanghai Jiaotong University School of Medicine were included, in which 62 isolates were from male patients and 81 isolates were isolated from sputum samples. A total of 86 patients had underlying diseases. All of the patients had received antibiotic therapeutics. The multilocus sequence typing (MLST) analysis indicated that 61 different sequence types (STs) were found (including 45 novel STs), and the MLST did not show significantly dominant STs. Pulsed field gel electrophoresis (PFGE) results showed the 93 isolates could be divided into 73 clusters, and they also showed weak genetic linkage between isolates. The resistant rates to Trimethoprim/sulfamethoxazole (TMP/SMX) and levofloxacin were 9.7% and 4.3%, respectively, and all of the isolates were susceptible to minocycline. The positive rates of the four virulence genes Stmpr1, Stmpr2, Smf-1, and Smlt3773 locus were 79.6%, 91.4%, 94.6%, and 52.7%, respectively. The positive rates of the three biofilm genes rmlA, spgM, and rpfF were 82.8%, 92.5%, and 64.5%, respectively. The mean biofilm forming level of OD492 was 0.54 ± 0.49, and there was no significant difference between different genders and different age groups. Data from patients in the intensive care unit (ICU) and the control group were analyzed retrospectively, and the independent risk factors of those who were infected in the ICU included immunosuppression and the increased of the antibiotics usage.Conclusions: Most of the patients had prior medical usage histories and baseline diseases. The positive rate of virulence genes was high, the drug resistance rate of S. maltophilia was low, and the biofilm formation ability was strong. The increased use of antibiotics was an independent risk factor for S. maltophilia infection, which should receive more attention. No obvious clonal transmission was found in the same department.

scholarly journals Neisseria meningitidis carriage and risk factors among teenagers in Suizhou city in China

2020 ◽  
Vol 148 ◽  
Author(s):  
Fei He ◽  
Hong mei Yang ◽  
Guo ming Li ◽  
Bing qing Zhu ◽  
Yating Zhang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Population Density ◽  
Neisseria Meningitidis ◽  
Old Age ◽  
Age Groups ◽  
Significant Risk ◽  
Epidemiological Data ◽  
Significant Risk Factor ◽  
Antibiotic Use ◽  
Carriage Rate

Abstract Teenagers are important carriers of Neisseria meningitidis, which is a leading cause of invasive meningococcal disease. In China, the carriage rate and risk factors among teenagers are unclear. The present study presents a retrospective analysis of epidemiological data for N. meningitidis carriage from 2013 to 2017 in Suizhou city, China. The carriage rates were 3.26%, 2.22%, 3.33%, 3.53% and 9.88% for 2013, 2014, 2015, 2016 and 2017, respectively. From 2014 to 2017, the carriage rate in the 15- to 19-year-old age group (teenagers) was the highest and significantly higher than that in remain age groups. Subsequently, a larger scale survey (December 2017) for carriage rate and relative risk factors (population density, time spent in the classroom, gender and antibiotics use) were investigated on the teenagers (15- to 19-year-old age) at the same school. The carriage rate was still high at 33.48% (223/663) and varied greatly from 6.56% to 52.94% in a different class. Population density of the classroom was found to be a significant risk factor for carriage, and 1.4 persons/m2 is recommended as the maximum classroom density. Further, higher male gender ratio and more time spent in the classroom were also significantly associated with higher carriage. Finally, antibiotic use was associated with a significantly lower carriage rate. All the results imply that attention should be paid to the teenagers and various measures can be taken to reduce the N. meningitidis carriage, to prevent and control the outbreak of IMD.

scholarly journals Psychological Symptoms in Young Adult Migraineurs

2020 ◽  
Vol 11 (1) ◽  
pp. 42
Author(s):  
Turgay Akalin ◽  
Aysin Sinal
Keyword(s):  
Interpersonal Relationships ◽  
Significant Relationship ◽  
Psychological Symptoms ◽  
Pearson Correlation ◽  
Psychological Symptom ◽  
Age Groups ◽  
Control Group ◽  
Migraine Headaches ◽  
Significant Difference ◽  
Group 2

We aimed to reveal psychological symptoms of young university students (18-25 y/o) with no secondary disease with complaints of migraine headaches. We compared the psychological symptoms with a young control group that did not present headaches and other studies examining migraines in different age groups to determine any similarities. The study consisted of 75 migraine cases; 13 with aura and 62 without aura) and 42 non-headache control subjects. The International Classification of Headache Disorders 3 (ICHD-3) with criteria questions and the Psychological Symptom Research Scale were applied to all participants and SPSS Statistics Program evaluated the data. Findings: 1) In the test of Descriptive Statistics for the Sample of Students, average values of both sexes were taken and found the average values of the migraine groups were higher than control group. 2) The Anova Test found differences in the diagnostic group besides depression (Somatisation p<., others p<.01) with no significant difference in depression (p=0.315). 3)The Pearson Correlation Analysis, found no association between age and psychological symptoms. There’s a significant relationship between psychological symptoms with somatisation (besides paranoid) (p<.05). There’s a significant relationship between depression and other psychological symptoms (p<.05). There’s a significant relationship between anxiety, obsession, interpersonal relationships, psychoticism, paranoia, anger, phobia, additional scale and other psychological symptoms (p<.01). Result: The study demonstrated psychological symptoms in young migraineurs. The average psychological symptoms of both migraine groups were higher than the control group, this showed psychological symptom similarities between young migraineurs and migraine patients of different age groups.

scholarly journals Studying the Effectiveness of Prevention Training Program of Drug Abuse on Reducing Risk Factors in Soldiers and Staffs

2018 ◽  
Vol 10 (1.SP) ◽  
pp. 20
Author(s):  
Parviz DABAGHI ◽  
Seyyed-Javad HOSSEINI-SHOKOUH ◽  
Reza SHAHRABADI
Keyword(s):  
Risk Factors ◽  
Drug Abuse ◽  
Training Program ◽  
Life Skills ◽  
Intervention Group ◽  
Skills Training ◽  
Demographic Variables ◽  
Control Group ◽  
Significant Difference ◽  
Prevention Training

Background and objective:    Drug abuse is one of the diseases that are highly dependent on individual behaviors and social interactions. This disease can be created in places like military garrisons due to their relationship with such behaviors. Therefore, soldiers and staffs are at risk of drug abuse. The aim of this study was to determine the effect of prevention training program of drug abuse on reducing risk factors in soldiers and staffs in Iran.Methods:In this quasi-experimental interventional study, 392 soldiers and staffs in two military garrisons in Khorasan Razavi (Intervention group 242 and control group 150) were randomly conducted to training program. The data collection tools were questionnaire of identifying people in risk of addiction, life skills questionnaire and demographic variables. The questionnaires were completed as self-report. Educational content was consisted of seven training sessions (60-minute) that only applied in the intervention group. 45 days after the last training session, educational software was distributed as a reminder in the intervention group. The two groups were followed up three months after the intervention. Finally, the data were analyzed using SPSS version 16.Results:  The findings showed that there was no significant difference between the two groups in demographic variables (Pvalue>0.05). The mean scores for risk factors on drug abuse after training program (Depression and feeling of inability, Positive attitude toward drug abuse and Anxiety and fearing of others) were significantly improved in the intervention group (Pvalue<0.05). Also, life skills variables except the problem solving skill (Pvalue>0.05) had a significant change after intervention in the intervention group (Pvalue<0.05).Conclusion:The findings indicated that the prevention training program of drug abuse based on life skills training could reduce the risk factors of drug abuse for soldiers and staffs in military garrisons.

scholarly journals Prevalence of Hepatitis B among Food Vendors in Wurukum Market, Makurdi Benue State

2018 ◽  
pp. 1-5
Author(s):  
V. U. Obisike ◽  
C. M. Uke ◽  
E. U. Amuta
Keyword(s):  
Risk Factors ◽  
Liver Disease ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Age Groups ◽  
Hbv Infection ◽  
Test Strips ◽  
Significant Difference ◽  
B Virus ◽  
Life Threatening

Hepatitis B is a life threatening infectious liver disease caused by hepatitis B virus (HBV). The aim of this study was to determine the prevalence of HBV among food vendors in Wurukum, a highly commercial section of metropolitan Makurdi in Benue State. The test was carried out with the use of an immunochromatographic  micropoint HBsAg test strips and a HBsAg  buffer screen for the virus. Out of the 250 non-vaccinated food vendors sampled, 27(10.8%) had HBV infection, with more in males (21.7%) than in females (6.6%). No significant difference (p>0.05) was found among age groups in spite of the observed highest prevalence of 14.3% among the 20-29 year olds. Therefore, the need for routine screening cannot be overemphasized in spite of known risk factors among food vendors.

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