scholarly journals Two rare cases of ovarian collision tumor

2020 ◽  
Author(s):  
yan tian ◽  
xinshan cao ◽  
mimi ma ◽  
yunfu cui ◽  
qingchao mu
Keyword(s):  
Lower Abdominal Pain ◽  
Cystic Teratoma ◽  
Pelvic Mass ◽  
Collision Tumor ◽  
Serous Cystadenoma ◽  
Biological Behavior ◽  
Anatomical Site ◽  
Normal Range ◽  
Primary Tumors ◽  
Case Presentation

Abstract Background: Collision tumor is a clinically rare disease, it is defined as two or more primary tumors from different tissues occurring at the same anatomical site. Ovarian collision tumor is more rare. Case presentation: A patient was hospitalized with a pelvic mass. The CA125 level was 53.46U per milli liter (normal range, 0 to 30u/ml). Another patient was hospitalized with lower abdominal pain and no apparent hormonal abnormalities. Ovarian lesions were found in both patients after examination, and postoperative pathology showed that both patients were ovarian collision tumors. Conclusion: Collision tumor composed of mature cystic teratoma, follicular membranous cell tumor and serous cystadenoma was first reported. The biological behavior of collision tumor is different due to its different components. Accurate diagnosis is of great significance to treatment.

Clinico-pathological profile of ovarian cysts in a tertiary care hospital

2017 ◽  
Vol 6 (10) ◽  
pp. 4642 ◽  
Author(s):  
Sairem Mangolnganbi Chanu ◽  
Biswajit Dey ◽  
Vandana Raphael ◽  
Subrat Panda ◽  
Yookarin Khonglah
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Lower Abdominal Pain ◽  
Cystic Teratoma ◽  
Serous Cystadenoma ◽  
Mature Cystic Teratoma ◽  
Ovarian Cysts ◽  
Histopathological Diagnosis ◽  
Care Hospital ◽  
North East

Background: Ovarian cystic neoplasms are common in gynaecological practice. These may pose diagnostic difficulty to the pathologists. This study was conducted to analyse the clinical and histological profile of ovarian cystic neoplasms.Methods: This is a retrospective study done from January 2016 to April 2017 in a tertiary care hospital in North East India. All the patients, who were clinically and radiologically diagnosed as ovarian cysts, which had histopathological confirmation were included in the study. Data including the age, parity, clinical symptoms, laterality and histopathological findings were analysed.Results: A total of 101 patients operated for ovarian cysts in the study period were analysed. The most common clinical presentation was lower abdominal pain. There were 11 (10.9%) malignant cases, 4 (4%) were intermediate grade and borderline in nature, and 85 (84.1%) cases were benign in nature. There was 1 (1%) case of metastasis to ovary. Mature cystic teratoma was most common (20.8%) histopathological diagnosis. The second most common cyst was serous cystadenoma (19.8%).Conclusion: Ovarian cysts are commonly encountered in gynaecological practice and equally encountered by the pathologists. Most commonly found ovarian cysts were mature cystic teratoma followed by serous cystadenoma.

scholarly journals Endometrioid adenocarcinoma of the rectovaginal septum with invasion of the rectum: a case report and review of literature

2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Hua Yang ◽  
Jiao-jiao Gu ◽  
Yue Qi ◽  
Wei Zhao ◽  
Xin-lu Wang
Keyword(s):  
Lower Abdominal Pain ◽  
Pelvic Mass ◽  
Preoperative Imaging ◽  
Histopathological Diagnosis ◽  
Endometrioid Adenocarcinoma ◽  
Rectovaginal Septum ◽  
Case Presentation ◽  
Additional Chemotherapy ◽  
Good Treatment Response ◽  
Gynecological Tumor

Abstract Background Malignant transformation of endometriosis in the rectovaginal septum is rare and usually misdiagnosed as a colorectal or gynecological tumor. We report a rare case of primary endometrioid adenocarcinoma of the rectovaginal septum with invasion of the rectum. Case presentation A 57-year-old overweight woman presented with vaginal bleeding and self-reported left lower abdominal pain during the previous 2 weeks. Preoperative imaging showed a large pelvic mass with invasion of the rectum, suggestive of a gynecologic malignancy. Multiple endoscopic biopsies and immunohistochemical analyses of specimens was performed. The patient received joint gynecological-surgical laparotomy, and there were no intra- or postoperative complications. The histopathological diagnosis was rectovaginal endometrioid adenocarcinoma with rectum infiltration. The patient received adjuvant chemotherapy and achieved good treatment response, with no early complications. At 12 months after surgery, there was no evidence of recurrence. Conclusions A high index of clinical suspicion is required for the diagnosis of endometrioid adenocarcinoma in the rectovaginal septum. Surgery combined with additional chemotherapy or radiotherapy seems to be a standard treatment, and hormonal therapy is optional. The efficacies of other therapies, including targeted medication and immunotherapy, are unknown.

scholarly journals Torsion of dermoid cyst in a perimenopausal woman: a case report

2018 ◽  
Vol 7 (10) ◽  
pp. 4321
Author(s):  
Kondareddy Radhika ◽  
Sonam Singh ◽  
Munikrishna M.
Keyword(s):  
Dermoid Cyst ◽  
Histopathological Examination ◽  
Lower Abdominal Pain ◽  
Cystic Teratoma ◽  
Pelvic Mass ◽  
Total Abdominal Hysterectomy ◽  
Mature Cystic Teratoma ◽  
Gravid Uterus ◽  
Abdominal Ultrasonography ◽  
Perimenopausal Woman

Mature cystic teratoma comprise 20-30% of all ovarian tumours. They are mostly seen in patients between 20 and 40 years of age and are mostly asymptomatic. Incidence of malignancy is high in perimenopausal and postmenopausal group. Here, authors report a case of torsion of dermoid cyst presenting unusually in a 45-year-old perimenopausal woman with acute abdomen. A 45-year-old perimenopausal woman presented with lower abdominal pain of 8 hours duration and 3-4 episodes of vomiting. Abdominal examination revealed a regular, firm to cystic, tender abdomino-pelvic mass corresponding to the size of 28 weeks gravid uterus by palpation. Abdominal ultrasonography revealed the presence of right ovarian cyst measuring 12.9x12.8x10.1 cm. Total abdominal hysterectomy with bilateral salpingo oopherectomy was done. Histopathological examination confirmed mature cystic teratoma. Although mature cystic teratoma is rare after 40 years age, especially in perimenopausal women and are usually malignant in that age group, it can have an unusual age presentation at 45 years with benign nature as in present case.

scholarly journals Malignant degeneration of mature cystic teratoma of the ovary with small bowel metastasis incidental serous cystadenoma collision tumor of the right ovary

2021 ◽  
Vol 16 (11) ◽  
pp. 3275-3279
Author(s):  
Ahmed Abduljabbar ◽  
Mohammed Wazzan ◽  
Khaled Bahubaishi ◽  
Ibrahim Alghamdi ◽  
Muath Marghalani ◽  
...  
Keyword(s):  
Small Bowel ◽  
Cystic Teratoma ◽  
Collision Tumor ◽  
Serous Cystadenoma ◽  
Mature Cystic Teratoma ◽  
Malignant Degeneration ◽  
Small Bowel Metastasis ◽  
The Right

scholarly journals A Large Parasitic Dermoid Cyst in The Pouch of Douglas, A Torsion Complication?

2021 ◽  
pp. 169-172
Author(s):  
Luay Abu Atileh ◽  
Nouf Khalifeh
Keyword(s):  
Dermoid Cyst ◽  
Ovarian Tissue ◽  
Lower Abdominal Pain ◽  
Cystic Teratoma ◽  
Cystic Mass ◽  
Mature Cystic Teratoma ◽  
En Bloc ◽  
Case Presentation ◽  
Pouch Of Douglas ◽  
The Right

Abstract Objectives: To identify the underlying etiology of dermoid cysts in the pouch of Douglas. Case presentation: A 44-year-old woman presented to our clinic complaining of chronic, dull-aching lower abdominal pain of one-month duration. Pelvic ultrasound examination showed an eight-centimeter cystic appearing lesion in the right adnexa. Computed tomography (CT) suggested the diagnosis of dermoid cyst. Laparoscopy revealed a residual ovarian tissue on the right side and an eight-centimeter cystic mass occupying the pouch of Douglas. The entire specimen was removed en bloc through the umbilicus incision inside a bag with no spillage. Histopathologic examination confirmed the diagnosis of a mature cystic teratoma. Conclusion: Parasitic dermoid cysts are extremely rare entity especially those located in the pouch of Douglas. Autoamputation and reimplantation is the most accepted etiology to explain this phenomenon.   Key-words: Autoamputation, dermoid cyst, Douglas, Laparoscopy, Mature cystic teratoma  

scholarly journals Atypical Presentation of Complicated Dermoid Cyst of Ovary Mimicking Diverticular Abscess

2021 ◽  
Vol 8 (6) ◽  
pp. 30-34
Author(s):  
Prasun Das ◽  
Sudipta Basu ◽  
Srijak Bhattacharyya
Keyword(s):  
Abdominal Pain ◽  
Sigmoid Colon ◽  
Dermoid Cyst ◽  
Lower Abdominal Pain ◽  
Cystic Teratoma ◽  
Case Presentation ◽  
Ovarian Neoplasia ◽  
Well Differentiated ◽  
Post Menopausal ◽  
Derivatives Of

Background: Cystic teratomas comprises 20% overall among all ovarian neoplasia. They are made of derivatives of at least two of three germ layers. Histologically different dermoid cyst contains only well differentiated embryological elements of ectodermal layer. Diverticulitis of colon mainly affects elderly population having abscess formation causing lower abdominal pain. Case presentation: We report a case of 50 yr old woman presenting with lower abdominal pain. From barium enema, ultrasound and CT we suggested the probability of diverticular abscess. Patient was undergone left salpingo-oophorectomy with repair of adhered part of sigmoid colon. Post op biopsy shows typical features of dermoid cyst. Conclusions: We illustrate how a dermoid cyst may be diagnosed as diverticular abscess by imaging. We also showed the rupture of dermoid cyst into sigmoid colon with communication formation. So we the radiologists must be aware of all possible differential diagnosis of lower abdominal pain in elderly female, so that we can help our fellow surgeons to treat properly. Keywords: Cystic teratoma, Diverticulitis, Post menopausal, Sigmoid Colon.

Histopathological Analysis of Neoplastic and Non-Neoplastic Lesions of Ovary : A 4 Year Study in Eastern Nepal

2017 ◽  
Vol 2 (2) ◽  
pp. 168-174
Author(s):  
Mrinalini Singh ◽  
KK Jha ◽  
SU Kafle ◽  
R Rana ◽  
P Gautam
Keyword(s):  
Cystic Teratoma ◽  
Pelvic Mass ◽  
Abdominal Hysterectomy ◽  
Serous Cystadenoma ◽  
Mature Cystic Teratoma ◽  
Histopathological Analysis ◽  
Medical College ◽  
Follicular Cyst ◽  
Neoplastic Lesion ◽  
Neoplastic Lesions

IntroductionOvarian neoplastic and nontineoplastic lesions form a pelvic mass and cause gynaecological problems. Therefore, proper recognization and classification is important for appropriate therapy.ObjectiveTo study the morphological patiern and classify the neoplastic and nontineoplastic ovarian lesions in terms of age and size.MethodologyA retrospective study conducted at Sriram Diagnostic Clinic, Biratnagar, Nepal and Birat Medical College, Tankisinwari, Morang, Nepal during a period of March 2012 to February 2016. All abdominal hysterectomy specimens with bilateral or unilateral salpingo-oophorectomy and all ovarian surgeries presenting with either solid or cystic ovarian lesions were included in the study for histopathological analysis. Normal appearing ovaries on gross and microscopic examination were excluded from the study.ResultsA total of 522 cases were studied. Out of which 329 (63%) were non-neoplastic and 193 (37%) were neoplastic. Follicular cysts comprised of 112 (34%) cases, and it was the most common non neoplastic lesion. The age of patients with non-neoplastic lesions and neoplastic lesions varied from 16-54 years and 13-72 years respectively. Size of nonneoplastic and neoplastic lesions varied from 2-12 cm and 2- 19 cm respectively. Among the 193 neoplastic ovarian lesions, 181 (94 %) were benign, as well as 4 (2%) were borderline and 8 (4 %) were malignant. Mature cystic teratoma was the commonest benign tumor followed by Serous cystadenoma. Serous cystadenocarcinoma was the commonest occurring malignant tumor followed by Mucinouscystadenocarcinoma.ConclusionVarying types of both non neoplastic and neoplastic ovarian lesion were seen. Among the non-neoplastic and neoplastic lesion, the most commonly encountered lesion was follicular cyst and mature cystic teratoma respectively.Birat Journal of Health SciencesVol.2/No.1/Issue 2/ Jan - April 2017, Page: 168-174

scholarly journals Head and Neck Cancers Are Not Alike When Tarred with the Same Brush: An Epigenetic Perspective from the Cancerization Field to Prognosis

Cancers ◽  
2021 ◽  
Vol 13 (22) ◽  
pp. 5630
Author(s):  
Diego Camuzi ◽  
Tatiana de Almeida Simão ◽  
Fernando Dias ◽  
Luis Felipe Ribeiro Pinto ◽  
Sheila Coelho Soares-Lima
Keyword(s):  
Risk Factor ◽  
Head And Neck ◽  
Molecular Mechanisms ◽  
Current Knowledge ◽  
Response To Therapy ◽  
Field Cancerization ◽  
Biological Behavior ◽  
Second Primary ◽  
Anatomical Site ◽  
Primary Tumors

Head and neck squamous cell carcinomas (HNSCC) are among the ten most frequent types of cancer worldwide and, despite all efforts, are still diagnosed at late stages and show poor overall survival. Furthermore, HNSCC patients often experience relapses and the development of second primary tumors, as a consequence of the field cancerization process. Therefore, a better comprehension of the molecular mechanisms involved in HNSCC development and progression may enable diagnosis anticipation and provide valuable tools for prediction of prognosis and response to therapy. However, the different biological behavior of these tumors depending on the affected anatomical site and risk factor exposure, as well as the high genetic heterogeneity observed in HNSCC are major obstacles in this pursue. In this context, epigenetic alterations have been shown to be common in HNSCC, to discriminate the tumor anatomical subsites, to be responsive to risk factor exposure, and show promising results in biomarker development. Based on this, this review brings together the current knowledge on alterations of DNA methylation and microRNA expression in HNSCC natural history, focusing on how they contribute to each step of the process and on their applicability as biomarkers of exposure, HNSCC development, progression, and response to therapy.

scholarly journals Cutaneous mucinosis of infancy: a rare case of joint involvement

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Cristina Morreale ◽  
Dario Bleidl ◽  
Angela Rita Sementa ◽  
Clara Malattia
Keyword(s):  
Rare Case ◽  
Steroid Injection ◽  
Left Knee ◽  
Joint Involvement ◽  
Normal Range ◽  
Reticular Dermis ◽  
Case Presentation ◽  
Left Elbow ◽  
Inflammatory Drugs ◽  
One Year

Abstract Background Primary cutaneous mucinosis are a heterogeneous group of diseases characterized by the deposition of glycosaminoglycans in the dermis and the follicles. These diseases are rare in children therefore their diagnosis and management are still challenging. Joint involvement has been reported in patients with secondary cutaneous mucinosis and, rarely, in primary mucinosis. We describe a case of Cutaneous Mucinosis of Infancy with joint involvement. Case presentation An healthy 5-year-old boy showed acute arthritis of the left knee and left elbow confirmed by ultrasound. Laboratory tests were within normal range. Symptoms disappeared after a course of nonsteroid anti-inflammatory drugs. One year later, the knee swelling reappeared; juvenile idiopathic arthritis was diagnosed and intra-articular steroid injection was performed. Due to persistence of arthritis of the knee he was admitted to our hospital. On physical examination variable skin-colored lesions were observed, which had been in existence for over 2 years. We performed a skin biopsy that showed an interstitial mucine deposition in the reticular dermis. Cutaneous Mucinosis of Infancy was diagnosed. Discussion and conclusions Cutaneous Mucinosis of Infancy is a persistent dermatosis with benign prognosis and no treatment is generally required. Our case report is particularly interesting because it is the first in which joint involvement has been reported in CMI, a disorder that has so far been described as limited to skin involvement. Further studies will be necessary in order to clarify the pathogenesis of joint involvement in primary mucinosis.

scholarly journals Solitary fibrous tumor of the greater omentum: case report and review of literature

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Karim M. Eltawil ◽  
Carly Whalen ◽  
Bryce Knapp
Keyword(s):  
Solitary Fibrous Tumor ◽  
Management Strategy ◽  
Abdominal Mass ◽  
Lower Abdominal Pain ◽  
Greater Omentum ◽  
Team Approach ◽  
Review Of Literature ◽  
Case Presentation ◽  
Multidisciplinary Team Approach ◽  
Fibrous Tumor

Abstract Background Solitary fibrous tumor (SFT) is a rare neoplasm of mesenchymal origin occurring most often in the visceral pleura, however, it has been described in almost every anatomic location of the human body. While most SFTs have a benign behavior, they can potentially be locally aggressive and demonstrate a malignant behavior. Case presentation A 63 year-old male patient presented with lower abdominal pain and nausea and was noted on CT to have a large, heterogeneous lower abdominal mass with no evidence of metastatic disease. A surgical resection was performed and the mass appeared to be connected to the greater omentum with a vascular pedicle. It was not invading any intra-abdominal or pelvic organs. Pathology revealed an SFT of omental origin. The mitotic count was less than 4 per 10 high-power fields and all pathologic characteristics did not meet the criteria for a malignant SFT. Conclusions We report an extremely rare case of SFT originating from the greater omentum. A multidisciplinary team approach was followed to plan the patient’s management strategy.

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