scholarly journals Association between absolute eosinopenia and mortality in SARS-COV-2 infection on the 70+, a discussed observation

2021 ◽  
Author(s):  
Edouard Baudouin ◽  
Jill Kosowki ◽  
Lea Mesinele ◽  
Tom Pujol ◽  
Nicoletta Brunetti ◽  
...  
Keyword(s):  
Older Adults ◽  
Daily Living ◽  
Geriatric Patients ◽  
Kidney Injury ◽  
Geriatric Ward ◽  
Survivor Group ◽  
Failure Assessment ◽  
Qsofa Score ◽  
The Impact ◽  
Deceased Patient

Abstract Background: This study aimed to seek for an association between absolute eosinopenia (eosinophils count < 10 /mm3) and mortality in an older adults suffering from COVID-19 hospitalized in a specific geriatric ward. Methods: This observational retrospective study was conducted in a French geriatric ward from March 17 to April 18, 2020. All 118 patients hospitalized for COVID-19 over 70 yo in acute stay care were enrolled. Patients with a treatment or a pathology which could interfere with eosinophil count were excluded. Results: No statistical difference was found between surviving or deceased patient regarding age (mean age (SD): 87 years (7)) and sex (34% of males). Differences for the most frequent acute events were statically different: Quick Sepsis-related Organ Failure Assessment (qSOFA) score was ≥ 2 at admission for 23% in the survivor group vs. 23 (72%) in the deceased (p < .001); acute kidney injury concerned 17% of the survivors vs. 69% of the decease (p< .001). Eosinopenia < 10/mm3 was significantly associated with mortality (OR (CI95%)) = 3.5 (1.2-11.4) after adjustment on age, gender, and activity of daily living. Conclusion: Absolute eosinopenia was associated with in hospital mortality in older adults. This result, if confirmed in other study, may help to predict the outcome of a SARS-COV-2 infection on geriatric patients and calls for immunologist to explore more globally the impact of inflammaging on the SARS-CoV-2 infection.

scholarly journals Predictors for Early Discharge Planning of Hospitalized Acute Geriatric Patients, a Retrospective Study

2021 ◽  
Vol 7 (2) ◽  
pp. 1-8
Author(s):  
Bernhard Hoppe ◽  
Keyword(s):  
Older Adults ◽  
Retrospective Study ◽  
Activities Of Daily Living ◽  
Medical Care ◽  
Daily Living ◽  
Geriatric Patients ◽  
Discharge Planning ◽  
Early Discharge ◽  
Comprehensive Treatment ◽  
Geriatric Ward

Purpose: When treated for an acute disorder, older adults are vulnerable for functional losses and the need of care after discharge. In a specialised geriatric ward, patients get a comprehensive treatment complementary to medical care in order to maintain and improve mobility and Activities of Daily Living (ADL) to facilitate the return to domesticity.

scholarly journals The Impact of Body Mass Index and Weight Changes on Disability Transitions and Mortality in Brazilian Older Adults

2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Flávia Cristina Drumond Andrade ◽  
Ahmad Iqmer Nashriq Mohd Nazan ◽  
Maria Lúcia Lebrão ◽  
Yeda Aparecida de Oliveira Duarte
Keyword(s):  
Older Adults ◽  
Body Mass Index ◽  
Body Mass ◽  
Daily Living ◽  
Well Being ◽  
Normal Weight ◽  
Multinomial Regression ◽  
Weight Changes ◽  
Health Transitions ◽  
The Impact

The aim of this study was to examine the association between body mass index and weight changes on disability transitions and mortality among Brazilian older adults. Longitudinal data from the Health, Well-Being, and Aging in Latin America and the Caribbean Study conducted in São Paulo, Brazil (2000 and 2006), were used to examine the impact of obesity on disability and mortality and of weight changes on health transitions related to disability. Logistic and multinomial regression models were used in the analyses. Individuals who were obese were more likely than those of normal weight to have limitations on activities of daily living (ADL), instrumental activity of daily living (IADL), and Nagi's limitations. Obesity was associated with higher incidence of ADL and IADL limitations and with lower recovery from Nagi's limitations. Compared to those who maintained their weight, those who gained weight experienced higher incidence of ADL and Nagi's limitations, even after controlling for initial body mass index. Higher mortality among overweight individuals was only found when the reference category was “remaining free of Nagi limitations.” The findings of the study underline the importance of maintaining normal weight for preventing disability at older ages.

Exergaming as a tool to enhance strength, balance, gait, mobility, participation, self-efficacy for exercise and adherence in older adults

2020 ◽  
Vol 30 (Supplement_2) ◽  
Author(s):  
A C Martins ◽  
J Quatorze ◽  
D Guia
Keyword(s):  
Older Adults ◽  
Activities Of Daily Living ◽  
Functional Ability ◽  
Self Efficacy ◽  
Daily Living ◽  
Exercise Program ◽  
Community Dwelling ◽  
Step Test ◽  
Mobility Limitations ◽  
The Impact

Abstract Introduction It is projected that the number of adults aged 60 or above will be 1.4 billion in 2030 and 2.1 billion in 2050. With aging, mobility limitations can cause severe difficulties on being independent during activities of daily living. Exercise has been shown as effective to counteract the impact of aging, although it is hard to create adherence. Exergames, as they increase the appeal of exercise, show promising results in terms of participation and promotion of healthy behaviours. Objectives This study aimed at assessing the effectiveness of the Otago Exercise Program incorporated in FallSensing Exergames. Methodology Community-dwelling older adults aged 60 or over, were recruited from facilities in Coimbra, Portugal and randomized in two groups, 27 allocated to the intervention (IG) and 34 to the control (CG). Regular activities of daily living (CG) were compared to an Exergame program (IG). Assessments were made at baseline and re-assessments at 8 weeks/16 sessions, regarding strength, balance, walking speed, participation and self-efficacy for exercise. Results 61 older adults (77% female), mean ages were 82.22 (IG) and 87.26 (CG) years. After 8 weeks, CG demonstrated a decrease in functional ability. IG got improvement in Step test (p = 0.001), 4 Stage Balance Modified test (p = 0.001), Self-Efficacy for Exercise (p = 0.009) and Activities and Participation Profile Related to Mobility (p &lt; 0.001) questionnaires. Conclusion Exergaming was safe and effective in improving functional ability, participation and self-efficacy. Nevertheless, some considerations are necessary when prescribing an Exergames, mainly concerning frequency and intensity of the exercise program and participants’ age.

scholarly journals Trends in functional disability and cognitive impairment among the older adult in China up to 2060: estimates from a dynamic multi-state population model

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
John P. Ansah ◽  
Chi-Tsun Chiu ◽  
Aloysius Chia Wei-Yan ◽  
Tessa Lui Shi Min ◽  
David B. Matchar
Keyword(s):  
Older Adults ◽  
Cognitive Impairment ◽  
Daily Living ◽  
Population Model ◽  
Functional Disability ◽  
Health States ◽  
Term Care ◽  
State Population ◽  
Care Services ◽  
The Impact

Abstract Background Available evidence suggests that cognitive impairment (CI), which leads to deficits in episodic memory, executive functions, visual attention, and language, is associated with difficulties in the capacity to perform activities of daily living. Hence any forecast of the future prevalence of functional disability should account for the likely impact of cognitive impairment on the onset of functional disability. Thus, this research aims to address this gap in literature by projecting the number of older adults in China with functional disability and cognitive impairment while accounting for the impact of cognitive impairment on the onset of functional disability. Methods We developed and validated a dynamic multi-state population model which simulates the population of China and tracks the transition of Chinese older adults (65 years and older) from 2010 to 2060, to and from six health states—(i) active older adults without cognitive impairment, (ii) active older adults with cognitive impairment, (iii) older adults with 1 to 2 ADL limitations, (iv) older adults with cognitive impairment and 1 to 2 ADL limitations, (v) older adults with 3 or more ADL limitations, and (vi) older adults with cognitive impairment and 3 or more ADL limitations. Results From 2015 to 2060, the number of older adults 65 years and older in China is projected to increase, of which the number with impairment (herein referred to as individuals with cognitive impairment and/or activity of daily living limitations) is projected to increase more than fourfold from 17·9 million (17·8–18·0) million in 2015 to 96·2 (95·3–97·1) million by 2060. Among the older adults with impairment, those with ADL limitations only is projected to increase from 3·7 million (3·6–3·7 million) in 2015 to 23·9 million (23·4–24·6 million) by 2060, with an estimated annual increase of 12·2% (12·1–12·3); while that for cognitive impairment only is estimated to increase from 11·4 million (11·3–11·5 million) in 2015 to 47·8 million (47·5–48·2 million) by 2060—this representing an annual growth of 7·07% (7·05–7·09). Conclusion Our findings suggest there will be an increase in demand for intermediate and long-term care services among the older adults with functional disability and cognitive impairment.

scholarly journals The impact of near visual impairment on instrumental activities of daily living among community-dwelling older adults in Selangor

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Qiu Ting Kee ◽  
Mohd Harimi Abd Rahman ◽  
Norliza Mohamad Fadzil ◽  
Zainora Mohammed ◽  
Suzana Shahar
Keyword(s):  
Older Adults ◽  
Activities Of Daily Living ◽  
Visual Impairment ◽  
Daily Living ◽  
Visually Impaired ◽  
Community Dwelling ◽  
Activity Of Daily Living ◽  
Instrumental Activities ◽  
Iadl Disability ◽  
The Impact

Abstract Objective Near visual impairment (VI) is a common disability in an aging population. Near vision is crucial in activity of daily living including reading, smartphone and computer use and meal preparation. This study was conducted to determine the association between near visual acuity (VA) and contrast sensitivity (CS) with activity of daily living (ADL) among visually impaired older adults. Results A total of 208 participants aged  ≥  60 were recruited from the population-based longitudinal study on neuroprotective model for healthy longevity. Habitual near VA and CS were measured using Lighthouse near VA chart and Pelli-Robson CS chart, respectively. Lawton instrumental activities of daily living (IADL) was used to assess ADL. There are 41.8% participants with near visual impairment and 28.7% among them had IADL disability. Independent t test showed significant lower mean IADL score among visually impaired participants [t(206)  =  2.03, p  =  0.04]. IADL score significantly correlated with near VA (r  =   − 0.21, p  =  0.05) but not with CS (r  =   − 0.14, p = 0.21). Near VA (B  =   − 0.44, p  =  0.03) and age (B  =   − 0.07, p  =  0.01) significantly predicted IADL. The findings show poorer VA renders higher IADL disability, which may necessitate interventions to improve ADL among visually impaired older adults.

scholarly journals I GOT THIS! SUCCESSFUL AGING THROUGH THE MAINTENANCE OF AUTONOMY

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S719-S720
Author(s):  
Alexandria G Nuccio ◽  
Ashely M Stripling
Keyword(s):  
Older Adults ◽  
Life Satisfaction ◽  
Activities Of Daily Living ◽  
Measurement System ◽  
Successful Aging ◽  
Daily Living ◽  
Later Life ◽  
Well Being ◽  
Functional Autonomy ◽  
The Impact

Abstract As America ages, an increased interest has been placed on understanding the development and maintenance of autonomy in later life. This is of particular importance given the impact of autonomy on vitality, well-being, and mood within older adults (Warner et al., 2011). However, the research examining which aspects of autonomy directly impact successful aging remains underexplored. As such, the current study utilizes the Functional Autonomy Measurement System (SMAF) to better understand which facets of autonomy promote life satisfaction in older adults. Data included assessments of the Functional Autonomy Measurement System and data was derived from the Survey of Midlife in the US Database (MIDUS 3). Participants were primarily White/Caucasian (88.7%) and female (54.0%); with a mean age of 63.64 years (SD=11.35). A series of hierarchical multiple linear regressions revealed that higher levels of Mental Functions predicted increased life satisfaction scores in models adjusted for age, sex, race, marital status, and education (F=54.152,p&lt;0.001) and that higher levels of Communication (F=37.553,p&lt;0.001), Activities of Daily Living (F=33.495,p&lt;0.001), Mobility (F=37.311,p&lt;0.001), and Instrumental Activities of Daily Living (F=8.630,p&lt;0.001) also predicted increases in life satisfaction scores but to a lesser extent. The present findings suggest that higher levels of autonomy, both physically and mentally, result in higher satisfaction with life; with perceptions of cognitive independence producing the highest levels. Implications of the current findings include increased understanding of the multifaceted nature of autonomy, and provision of recommendations which could increase autonomous behavior in later life, thus increase life satisfaction and promote successful aging.

scholarly journals MO358ACUTE KIDNEY INJURY AND MORTALITY RISK IN OLDER ADULTS WITH AND WITHOUT COVID-19: DATA FROM GEROCOVID STUDY

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Hong Xu ◽  
Sara Garcia-Ptacek ◽  
Martin Annetorp ◽  
Annette Bruchfeld ◽  
Tommy Cederholm ◽  
...  
Keyword(s):  
Risk Factors ◽  
Older Adults ◽  
Kidney Function ◽  
Geriatric Patients ◽  
Vital Signs ◽  
Kidney Injury ◽  
Adverse Outcomes ◽  
Hospital Death ◽  
The Difference ◽  
Hospitalized Older Adults

Abstract Background and Aims Research regarding COVID-19 and acute kidney injury (AKI) in older adults is scarce. We evaluated the risk factors and outcomes of AKI in hospitalized older adults with and without COVID-19. Method Observational study of patients admitted to two geriatric clinics in the Stockholm Region of Sweden during the first wave of the COVID-19 pandemic from March 1st to June 15th 2020. The difference in incidence, risk factors and adverse outcomes for AKI between patients with or without COVID-19 were examined. Odds ratios (ORs) for AKI were obtained from logistic regressions. The hazard ratios (HRs) for the risk of in-hospital death were calculated from Cox proportional hazard regression models. Results We analyzed 316 older patients hospitalized for COVID-19 and 876 patients for non-COVID-19 diagnoses. The mean age was 83±9 years, 57% were women, and mean baseline kidney function as depicted by estimated glomerular filtration rate (eGFR) was 62±23 ml/min/1.73m2. AKI occurred in 92 (29%) of patients with COVID-19 vs. 159 (18%) without COVID-19. The severity of AKI was significantly worse in patients with COVID-19 compared with non-COVID patients. The odds for developing AKI were higher in patients with COVID-19 (adjusted OR, 1.70; 95% CI, 1.04-2.76), low baseline kidney function [4.19 (2.48-7.05), for eGFR 30 ∼ &lt;60 ml/min/1.73m2, and 20.3 (9.95-41.3) for eGFR &lt;30ml/min/1.73m2], and higher C-reactive protein (CRP) level (OR 1.81(1.11-2.95)). The risk of in-hospital death was highest in patients with COVID-19 and AKI [adjusted HR 23.5, 95% CI (8.75-63.0)], followed by COVID-19 without AKI [9.10 (3.52-23.6)] and by patients without COVID-19 and with AKI [6.38 (2.28-17.9)] after adjusting for patient demographics, vital signs, baseline kidney function and medications and using non-COVID patients with no AKI as reference. Conclusion Geriatric patients hospitalized with COVID-19 had a higher incidence of AKI compared with patients hospitalized with other diagnoses. AKI and COVID-19 were associated with in-hospital death. Optimal management of AKI may improve the outcome of COVID-19 in geriatric patients.

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