scholarly journals Can natural language processing help differentiate inflammatory intestinal diseases in China? Models applying random forest and convolutional neural network approaches

2020 ◽  
Author(s):  
Yuanren Tong ◽  
Keming Lu ◽  
Yingyun Yang ◽  
Ji Li ◽  
Yucong Lin ◽  
...  

Abstract Background: Differentiating between ulcerative colitis (UC), Crohn’s disease (CD) and intestinal tuberculosis (ITB) using endoscopy is challenging. We aimed to realize automatic differential diagnosis among these diseases through machine learning algorithms. Methods: A total of 6399 consecutive patients (5128 UC, 875 CD and 396 ITB) who had undergone colonoscopy examinations in the Peking Union Medical College Hospital from January 2008 to November 2018 were enrolled. The input was the description of the endoscopic image in the form of free text. Word segmentation and key word filtering were conducted as data preprocessing. Random forest (RF) and convolutional neural network (CNN) approaches were applied to different disease entities. Three two-class classifiers (UC and CD, UC and ITB, and CD and ITB) and a three-class classifier (UC, CD and ITB) were built. Results: The classifiers built in this research performed well, and the CNN had better performance in general. The RF sensitivities/specificities of UC-CD, UC-ITB, and CD-ITB were 0.89/0.84, 0.83/0.82, and 0.72/0.77, respectively, while the values for the CNN of CD-ITB were 0.90/0.77. The precisions/recalls of UC-CD-ITB when employing RF were 0.97/0.97, 0.65/0.53, and 0.68/0.76, respectively, and when employing the CNN were 0.99/0.97, 0.87/0.83, and 0.52/0.81, respectively.Conclusions: Classifiers built by RF and CNN approaches had excellent performance when classifying UC with CD or ITB. For the differentiation of CD and ITB, high specificity and sensitivity were achieved as well. Artificial intelligence through machine learning is very promising in helping unexperienced endoscopists differentiate inflammatory intestinal diseases.

2020 ◽  
Author(s):  
Yuanren Tong ◽  
Keming Lu ◽  
Yingyun Yang ◽  
Ji Li ◽  
Yucong Lin ◽  
...  

Abstract Background: Differentiating between ulcerative colitis (UC), Crohn’s disease (CD) and intestinal tuberculosis (ITB) using endoscopy is challenging. We aimed to realize automatic differential diagnosis among these diseases through machine learning algorithms. Methods: A total of 6399 consecutive patients (5128 UC, 875 CD and 396 ITB) who had undergone colonoscopy examinations in the Peking Union Medical College Hospital from January 2008 to November 2018 were enrolled. The input was the description of the endoscopic image in the form of free text. Word segmentation and key word filtering were conducted as data preprocessing. Random forest (RF) and convolutional neural network (CNN) approaches were applied to different disease entities. Three two-class classifiers (UC and CD, UC and ITB, and CD and ITB) and a three-class classifier (UC, CD and ITB) were built. Results: The classifiers built in this research performed well, and the CNN had better performance in general. The RF sensitivities/specificities of UC-CD, UC-ITB, and CD-ITB were 0.89/0.84, 0.83/0.82, and 0.72/0.77, respectively, while the values for the CNN of CD-ITB were 0.90/0.77. The precisions/recalls of UC-CD-ITB when employing RF were 0.97/0.97, 0.65/0.53, and 0.68/0.76, respectively, and when employing the CNN were 0.99/0.97, 0.87/0.83, and 0.52/0.81, respectively.Conclusions: Classifiers built by RF and CNN approaches had excellent performance when classifying UC with CD or ITB. For the differentiation of CD and ITB, high specificity and sensitivity were achieved as well. Artificial intelligence through machine learning is very promising in helping unexperienced endoscopists differentiate inflammatory intestinal diseases.


2020 ◽  
Author(s):  
Yuanren Tong ◽  
Keming Lu ◽  
Yingyun Yang ◽  
Ji Li ◽  
Yucong Lin ◽  
...  

Abstract Background: Differentiating between ulcerative colitis (UC), Crohn’s disease (CD) and intestinal tuberculosis (ITB) using endoscopy is challenging. We aimed to realize automatic differential diagnosis among these diseases through machine learning algorithms. Methods: A total of 6399 consecutive patients (5128 UC, 875 CD and 396 ITB) who had undergone colonoscopy examinations in the Peking Union Medical College Hospital from January 2008 to November 2018 were enrolled. The input was the description of the endoscopic image in the form of free text. Word segmentation and key word filtering were conducted as data preprocessing. Random forest (RF) and convolutional neural network (CNN) approaches were applied to different disease entities. Three two-class classifiers (UC and CD, UC and ITB, and CD and ITB) and a three-class classifier (UC, CD and ITB) were built.Results: The classifiers built in this research performed well, and the CNN had better performance in general. The RF sensitivities/specificities of UC-CD, UC-ITB, and CD-ITB were 0.89/0.84, 0.83/0.82, and 0.72/0.77, respectively, while the values for the CNN of CD-ITB were 0.90/0.77. The precisions/recalls of UC-CD-ITB when employing RF were 0.97/0.97, 0.65/0.53, and 0.68/0.76, respectively, and when employing the CNN were 0.99/0.97, 0.87/0.83, and 0.52/0.81, respectively.Conclusions: Classifiers built by RF and CNN approaches had excellent performance when classifying UC with CD or ITB. For the differentiation of CD and ITB, high specificity and sensitivity were achieved as well. Artificial intelligence through machine learning is very promising in helping unexperienced endoscopists differentiate inflammatory intestinal diseases.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Yuanren Tong ◽  
Keming Lu ◽  
Yingyun Yang ◽  
Ji Li ◽  
Yucong Lin ◽  
...  

Abstract Background Differentiating between ulcerative colitis (UC), Crohn’s disease (CD) and intestinal tuberculosis (ITB) using endoscopy is challenging. We aimed to realize automatic differential diagnosis among these diseases through machine learning algorithms. Methods A total of 6399 consecutive patients (5128 UC, 875 CD and 396 ITB) who had undergone colonoscopy examinations in the Peking Union Medical College Hospital from January 2008 to November 2018 were enrolled. The input was the description of the endoscopic image in the form of free text. Word segmentation and key word filtering were conducted as data preprocessing. Random forest (RF) and convolutional neural network (CNN) approaches were applied to different disease entities. Three two-class classifiers (UC and CD, UC and ITB, and CD and ITB) and a three-class classifier (UC, CD and ITB) were built. Results The classifiers built in this research performed well, and the CNN had better performance in general. The RF sensitivities/specificities of UC-CD, UC-ITB, and CD-ITB were 0.89/0.84, 0.83/0.82, and 0.72/0.77, respectively, while the values for the CNN of CD-ITB were 0.90/0.77. The precisions/recalls of UC-CD-ITB when employing RF were 0.97/0.97, 0.65/0.53, and 0.68/0.76, respectively, and when employing the CNN were 0.99/0.97, 0.87/0.83, and 0.52/0.81, respectively. Conclusions Classifiers built by RF and CNN approaches had excellent performance when classifying UC with CD or ITB. For the differentiation of CD and ITB, high specificity and sensitivity were achieved as well. Artificial intelligence through machine learning is very promising in helping unexperienced endoscopists differentiate inflammatory intestinal diseases. Conference The abstract of this article has won the first prize of the Young Investigator Award during the Asian Pacific Digestive Week (APDW) 2019 held in Kolkata, India.


2020 ◽  
Vol 14 (Supplement_1) ◽  
pp. S247-S248
Author(s):  
Y Li ◽  
Y Tong ◽  
K Lu ◽  
S Yu ◽  
J Qian

Abstract Background Differentiating between ulcerative colitis (UC), Crohn’s disease (CD) and intestinal tuberculosis (ITB) is challenging under endoscopy. We aimed to realise automatic differential diagnosis among these diseases through machine learning algorithms. Methods A total of 6399 consecutive patients (5128 UC, 875 CD and 396 ITB) who had taken colonoscopy examinations in Peking Union Medical College Hospital from January 2008 to November 2018 was enrolled. The input was the description of the endoscopic image in the form of free-text. Word segmentation and key word infiltration were conducted as data pre-processing. Random forest (RF) and convolutional neural network (CNN) were applied to different disease entities. Three two-class classifiers (UC and CD, UC and ITB, CD and ITB) and a three-class classifier (UC, CD and ITB) were built. Sensitivity/specificity and precision/recall were applied to evaluate the performance of two-class classifiers and the three-class classifier, respectively. Results The classifiers built in this research were well-performed and the CNN had a better performance in general. The RF sensitivities/specificities of UC-CD, UC-ITB and CD-ITB were 0.89/0.84, 0.83/0.82 and 0.72/0.77, while the CNN of CD-ITB was 0.90/0.77. The precision/recall of UC-CD-ITB was 0.97/0.97, 0.65/0.53 and 0.68/0.76 by RF, respectively, and 0.99/0.97,0.87/0.83 and 0.52/0.81 by CNN, respectively. Conclusion Classifiers built by RF and CNN had an excellent performance when classifying UC with CD or ITB. For the differentiation of CD and ITB, high specificity and sensitivity were reached as well. Artificial intelligence through machine learning is very promising in helping unexperienced endoscopists differentiate inflammatory intestinal diseases.


Author(s):  
Sergiy Pogorilyy ◽  
Artem Kramov

The detection of coreferent pairs within a text is one of the basic tasks in the area of natural language processing (NLP). The state‑ of‑ the‑ art methods of coreference resolution are based on machine learning algorithms. The key idea of the methods is to detect certain regularities between the semantic or grammatical features of text entities. In the paper, the comparative analysis of current methods of coreference resolution in English and Ukrainian texts has been performed. The key disadvantage of many methods consists in the interpretation of coreference resolution as a classification problem. The result of coreferent pairs detection is the set of groups in which elements refer to a common entity. Therefore it is advisable to consider the coreference resolution as a clusterization task. The method of coreference resolution using the set of filtering sieves and a convolutional neural network has been suggested. The set of filtering sieves to find candidates for coreferent pairs formation has been implemented. The training process of a multichannel convolutional neural network on a marked Ukrainian corpus has been performed. The usage of a multichannel structure allows analyzing of the different components of text units: semantic, lexical, and grammatical features of words and sentences. Furthermore, it is possible to process input data with unfixed size (words or sentences of a text) using a convolutional layer. The output result of the method is the set of clusters. In order to form clusters, it is necessary to take into account the previous steps of the model’s workflow. Nevertheless, such an approach contradicts the traditional methodology of machine learning. Thus, the training process of the network has been performed using the SEARN algorithm that allows the solving of tasks with unfixed output structures using a classifier model. An experimental examination of the method on the corpus of Ukrainian news has been performed. In order to estimate the accuracy of the method the corresponding common metrics for clusterization tasks have been calculated. The results obtained can indicate that the suggested method can be used to find coreferent pairs within Ukrainian texts. The method can be also easily adapted and applied to other natural languages.


Author(s):  
E. Yu. Shchetinin

The recognition of human emotions is one of the most relevant and dynamically developing areas of modern speech technologies, and the recognition of emotions in speech (RER) is the most demanded part of them. In this paper, we propose a computer model of emotion recognition based on an ensemble of bidirectional recurrent neural network with LSTM memory cell and deep convolutional neural network ResNet18. In this paper, computer studies of the RAVDESS database containing emotional speech of a person are carried out. RAVDESS-a data set containing 7356 files. Entries contain the following emotions: 0 – neutral, 1 – calm, 2 – happiness, 3 – sadness, 4 – anger, 5 – fear, 6 – disgust, 7 – surprise. In total, the database contains 16 classes (8 emotions divided into male and female) for a total of 1440 samples (speech only). To train machine learning algorithms and deep neural networks to recognize emotions, existing audio recordings must be pre-processed in such a way as to extract the main characteristic features of certain emotions. This was done using Mel-frequency cepstral coefficients, chroma coefficients, as well as the characteristics of the frequency spectrum of audio recordings. In this paper, computer studies of various models of neural networks for emotion recognition are carried out on the example of the data described above. In addition, machine learning algorithms were used for comparative analysis. Thus, the following models were trained during the experiments: logistic regression (LR), classifier based on the support vector machine (SVM), decision tree (DT), random forest (RF), gradient boosting over trees – XGBoost, convolutional neural network CNN, recurrent neural network RNN (ResNet18), as well as an ensemble of convolutional and recurrent networks Stacked CNN-RNN. The results show that neural networks showed much higher accuracy in recognizing and classifying emotions than the machine learning algorithms used. Of the three neural network models presented, the CNN + BLSTM ensemble showed higher accuracy.


2020 ◽  
Author(s):  
Florian Dupuy ◽  
Olivier Mestre ◽  
Léo Pfitzner

<p>Cloud cover is a crucial information for many applications such as planning land observation missions from space. However, cloud cover remains a challenging variable to forecast, and Numerical Weather Prediction (NWP) models suffer from significant biases, hence justifying the use of statistical post-processing techniques. In our application, the ground truth is a gridded cloud cover product derived from satellite observations over Europe, and predictors are spatial fields of various variables produced by ARPEGE (Météo-France global NWP) at the corresponding lead time.</p><p>In this study, ARPEGE cloud cover is post-processed using a convolutional neural network (CNN). CNN is the most popular machine learning tool to deal with images. In our case, CNN allows to integrate spatial information contained in NWP outputs. We show that a simple U-Net architecture produces significant improvements over Europe. Compared to the raw ARPEGE forecasts, MAE drops from 25.1 % to 17.8 % and RMSE decreases from 37.0 % to 31.6 %. Considering specific needs for earth observation, special interest was put on forecasts with low cloud cover conditions (< 10 %). For this particular nebulosity class, we show that hit rate jumps from 40.6 to 70.7 (which is the order of magnitude of what can be achieved using classical machine learning algorithms such as random forests) while false alarm decreases from 38.2 to 29.9. This is an excellent result, since improving hit rates by means of random forests usually also results in a slight increase of false alarms.</p>


Author(s):  
Saranya N ◽  
◽  
Kavi Priya S ◽  

In recent years, due to the increasing amounts of data gathered from the medical area, the Internet of Things are majorly developed. But the data gathered are of high volume, velocity, and variety. In the proposed work the heart disease is predicted using wearable devices. To analyze the data efficiently and effectively, Deep Canonical Neural Network Feed-Forward and Back Propagation (DCNN-FBP) algorithm is used. The data are gathered from wearable gadgets and preprocessed by employing normalization. The processed features are analyzed using a deep convolutional neural network. The DCNN-FBP algorithm is exercised by applying forward and backward propagation algorithm. Batch size, epochs, learning rate, activation function, and optimizer are the parameters used in DCNN-FBP. The datasets are taken from the UCI machine learning repository. The performance measures such as accuracy, specificity, sensitivity, and precision are used to validate the performance. From the results, the model attains 89% accuracy. Finally, the outcomes are juxtaposed with the traditional machine learning algorithms to illustrate that the DCNN-FBP model attained higher accuracy.


2022 ◽  
pp. 1559-1575
Author(s):  
Mário Pereira Véstias

Machine learning is the study of algorithms and models for computing systems to do tasks based on pattern identification and inference. When it is difficult or infeasible to develop an algorithm to do a particular task, machine learning algorithms can provide an output based on previous training data. A well-known machine learning model is deep learning. The most recent deep learning models are based on artificial neural networks (ANN). There exist several types of artificial neural networks including the feedforward neural network, the Kohonen self-organizing neural network, the recurrent neural network, the convolutional neural network, the modular neural network, among others. This article focuses on convolutional neural networks with a description of the model, the training and inference processes and its applicability. It will also give an overview of the most used CNN models and what to expect from the next generation of CNN models.


Water ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 2927
Author(s):  
Jiyeong Hong ◽  
Seoro Lee ◽  
Joo Hyun Bae ◽  
Jimin Lee ◽  
Woon Ji Park ◽  
...  

Predicting dam inflow is necessary for effective water management. This study created machine learning algorithms to predict the amount of inflow into the Soyang River Dam in South Korea, using weather and dam inflow data for 40 years. A total of six algorithms were used, as follows: decision tree (DT), multilayer perceptron (MLP), random forest (RF), gradient boosting (GB), recurrent neural network–long short-term memory (RNN–LSTM), and convolutional neural network–LSTM (CNN–LSTM). Among these models, the multilayer perceptron model showed the best results in predicting dam inflow, with the Nash–Sutcliffe efficiency (NSE) value of 0.812, root mean squared errors (RMSE) of 77.218 m3/s, mean absolute error (MAE) of 29.034 m3/s, correlation coefficient (R) of 0.924, and determination coefficient (R2) of 0.817. However, when the amount of dam inflow is below 100 m3/s, the ensemble models (random forest and gradient boosting models) performed better than MLP for the prediction of dam inflow. Therefore, two combined machine learning (CombML) models (RF_MLP and GB_MLP) were developed for the prediction of the dam inflow using the ensemble methods (RF and GB) at precipitation below 16 mm, and the MLP at precipitation above 16 mm. The precipitation of 16 mm is the average daily precipitation at the inflow of 100 m3/s or more. The results show the accuracy verification results of NSE 0.857, RMSE 68.417 m3/s, MAE 18.063 m3/s, R 0.927, and R2 0.859 in RF_MLP, and NSE 0.829, RMSE 73.918 m3/s, MAE 18.093 m3/s, R 0.912, and R2 0.831 in GB_MLP, which infers that the combination of the models predicts the dam inflow the most accurately. CombML algorithms showed that it is possible to predict inflow through inflow learning, considering flow characteristics such as flow regimes, by combining several machine learning algorithms.


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