Schwannoma of the Posterior Pharyngeal Wall in a Child

Pharyngeal Wall ◽

First Case ◽

Severe Difficulty ◽

Abstract Background: To our knowledge, There are only 7 cases of posterior pharyngeal wall schwannoma which have been previously reported in the literature, but none of them was associated with a 3-year-old child.Case presentation: We presented a rare case of a schwannoma which is localized on the posterior pharyngeal wall, It caused severe difficulty in swallowing and breathing in a child whose age is three years old. Schwannomas of the posterior pharyngeal wall has been rarely reported in children, The tumor was removed with plasma radio frequency excision via a transoral route, There was not seen any recurrence of tumor by examination of CT or MRI up to two years. as far as we know, It's the first time which a case of posterior pharyngeal wall schwannoma that has been reported to occur in a 3-year-old child, and the first case in which the schwannoma was removed via transoral plasma radio frequency excision.Conclusions: This case illustrates that schwannoma may be found in children ,and it is safe to treat this disease through plasma radio frequency excision via a transoral route.

Rare Case of a Schwannoma of the Posterior Pharyngeal Wall in a Child

Ear Nose & Throat Journal ◽

10.1177/01455613211031027 ◽

2021 ◽

pp. 014556132110310

Author(s):

Peng Zhu ◽

Xiao Yan Li

Keyword(s):

Magnetic Resonance Imaging ◽

Computed Tomography ◽

Rare Case ◽

Magnetic Resonance Imaging Examination ◽

Resonance Imaging ◽

Pharyngeal Wall ◽

Severe Difficulty ◽

We present a rare case of a schwannoma which is localized on the posterior pharyngeal wall. It caused severe difficulty in swallowing and breathing in a 3-year-old child. Schwannomas of the posterior pharyngeal wall have been rarely reported in children. To our knowledge, only 7 cases of posterior pharyngeal wall schwannoma have been previously reported in the literature, but none of them is associated with a child. The tumor was removed with plasma radiofrequency excision via a transoral route. Computed tomography or magnetic resonance imaging examination showed no recurrence of the tumor up to 2 years. To our knowledge, for the first time, a case of posterior pharyngeal wall schwannoma has been reported in a 3-year-old child, and the schwannoma was removed via plasma radiofrequency transoral excision. This case study illustrates that schwannoma may occur in children, and it is safe to treat this disease through plasma radiofrequency transoral excision route.

Posterior pharyngeal wall schwannoma

The Journal of Laryngology & Otology ◽

10.1017/s002221510010266x ◽

1987 ◽

Vol 101 (7) ◽

pp. 749-752 ◽

Cited By ~ 12

Author(s):

C. Triaridis ◽

M. G. Tsalighopoulos ◽

A. Kouloulas ◽

A. Vartholomeos

Keyword(s):

Rare Case ◽

Posterior Wall ◽

Lateral Pharyngeal Wall ◽

Pharyngeal Wall ◽

Severe Difficulty ◽

Sympathetic Nervous

SummaryA rare case of a schwannoma localized on the posterior pharyngeal wall is presented. It concerns a young man with an inflammatory ulcerated mass in the posterior wall of the pharynx causing severe difficulty in swallowing.Although schwannomas of the lateral pharyngeal wall are common, only one case located on the posterior wall has been described. The origin of these tumours at this particular site is thought to be the sympathetic nervous plexus of the posterior pharyngeal wall.In presenting our case, we comment on the origin of posterior pharyngeal wall schwannomas.

Protruded duodenal tumor arising from Santorini’s duct of the pancreas: a rare case of intraductal papillary mucinous neoplasm mimicking a duodenal polypoid tumor

BMC Gastroenterology ◽

10.1186/s12876-020-01449-y ◽

2020 ◽

Vol 20 (1) ◽

Author(s):

Haruna Komatsubara ◽

Hiroyuki Kato ◽

Daisuke Noguchi ◽

Kazuyuki Gyoten ◽

Aoi Hayasaki ◽

...

Keyword(s):

Intraductal Papillary Mucinous Neoplasm ◽

Rare Case ◽

Resected Specimen ◽

Case Presentation ◽

Duodenal Tumor ◽

Mucinous Neoplasm ◽

First Case ◽

Enhanced Ct ◽

Duodenal Lumen ◽

Polypoid Tumor

Abstract Background We experienced a rare case of intraductal papillary mucinous neoplasm arising from Santorini’s duct (SD) forming a tumor protruding into the duodenum . Case presentation A 71-year-old woman was incidentally diagnosed with a 3 cm type Isp polypoid tumor in the second portion of the duodenum at another hospital. Enhanced CT and endoscopic ultrasound revealed that the origin of this protruding tumor was arising from SD and that the tumor mimicked a pedunculated duodenal tumor. Our preoperative diagnosis was a malignant pancreatic tumor arising from SD with invasion into the duodenum. She underwent a subtotal stomach-preserving pancreaticoduodenectomy, and the resected specimen showed a 25 mm tumor protruding into the duodenum with a villous surface. The pathological findings revealed that the tumor was intraductal papillary mucinous adenoma (IPMA) arising from SD. Conclusions To the best of our knowledge, this is the first case of IPMA protruding into the duodenal lumen from SD, although most of the tumors arising from SD have been reported to be malignant.

Cytological Features of a Variant NUT Midline Carcinoma of the Lung Harboring theNSD3-NUTFusion Gene: A Case Report and Literature Review

Case Reports in Pathology ◽

10.1155/2015/572951 ◽

2015 ◽

Vol 2015 ◽

pp. 1-5 ◽

Cited By ~ 4

Author(s):

Shiho Kuroda ◽

Shioto Suzuki ◽

Akira Kurita ◽

Mari Muraki ◽

Yoichiro Aoshima ◽

...

Keyword(s):

Case Report ◽

Nuclear Protein ◽

Lung Tumor ◽

Nut Midline Carcinoma ◽

Case Presentation ◽

First Case ◽

Cytological Features ◽

Pearl Formation ◽

Mitotic Figures ◽

Background. Nuclear protein in testis (NUT) midline carcinoma (NMC) is a very rare and aggressive malignancy. In more than two-thirds of these NMC cases, a fusion betweenNUTandBRD4orBRD3has been documented; other variants are rare. The cytology of NMC itself has been sparsely documented and that of variant NMC has never been reported.Case Presentation. A 36-year-old woman was admitted because of a rapidly progressing lung tumor with metastases to the breast and bone. We recently reported this patient as the first case of a variant NMC of the lung harboring anNSD3-NUTfusion, based on immunohistochemical and genetic analyses. Cytological material was available for the present review. A highly cellular smear contained a predominantly noncohesive pattern of monomorphic cells with diameters 2–2.5 times greater than those of small lymphocytes, with a round-to-oval nucleus, slightly irregular nuclear contours, variably prominent nucleoli, scant cytoplasm, and identifiable mitotic figures. Foci of stratification and overt pearl formation, including a dyskeratocyte, were occasionally observed. The necrotic background contained naked nuclei, karyorrhectic debris, apoptotic cells, and macrophages phagocytizing karyorrhectic debris; nuclear crushing was noted.Conclusion. The cytological features of a variant NMC of the lung are described for the first time.

Life threatening abscess in the visceral space with penicillin and metronidazole resistant Prevotella Denticola following use of a laryngeal mask airway: case report

BMC Anesthesiology ◽

10.1186/s12871-021-01322-9 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Hervé Vanden Eede ◽

Elizabeth Norris ◽

Michaël Torfs ◽

Olivier Vanderveken

Keyword(s):

Early Recognition ◽

Laryngeal Mask ◽

Pharyngeal Wall ◽

Case Presentation ◽

Respiratory Problems ◽

First Case ◽

Amoxicillin Clavulanate ◽

Life Threatening ◽

Single Use ◽

Day Care Centre

Abstract Background Laryngeal mask airways (LMA) are commonly used for airway management. Complications with this device are rare. However, when they do occur, there is a high risk for respiratory problems, necessitating early diagnosis and treatment. We present the first case of a life-threatening abscess spreading in the visceral space caused by a penicillin and metronidazole resistant Prevotella Denticola after the use of an LMA. Case presentation A female patient was admitted to our day care centre for bunion surgery. A single use LMA size 3 (Solus®, intersurgical, Wokingham, Berkshire, United Kingdom) was successfully inserted. After surgery, the patient complained of a sore throat and amoxicillin was prescribed by the general practitioner. Three days after surgery the patient was admitted to the Intensive Care Unit (ICU) for obstructive breathing, due to an abscess in the visceral space. Retropharyngeal and certainly parapharyngeal abscesses in adults are already rare. This case however, is unique because it is the first case of abscess spreading into the visceral space after the use of an LMA. Amoxicillin/clavulanate and vancomycin were started. The abscess was incised 5 days later and microbiology showed 3 positive cultures of the anaerobe Prevotella denticola, resistant for penicillin and metronidazole, but sensitive for amoxicillin/clavulanate. The patient fully recovered. Conclusion LMA’s are easy to use and are established, safe tools to support ventilation of the airway. In this case, the authors hypothesise a small wound in the lateral pharyngeal wall probably created an opening into the visceral space causing infection with Prevotella denticola, supporting the idea that the pharyngeal mucosal space must be part of the visceral space. Additionally, early recognition and treatment of an LMA induced abscess is necessary to prevent evolution of complications leading to airway obstruction.

A Rare Case of Drug-Induced Erectile Dysfunction with Secukinumab Solved After Switch to Ixekizumab in A Psoriatic Patient: A Case Report

Current Drug Safety ◽

10.2174/1574886314666190726155147 ◽

2020 ◽

Vol 15 (1) ◽

pp. 69-72

Author(s):

Stefano Dastoli ◽

Luigi Francesco Iannone ◽

Luigi Bennardo ◽

Martina Silvestri ◽

Caterina Palleria ◽

...

Keyword(s):

Adverse Effect ◽

Erectile Dysfunction ◽

Sexual Dysfunction ◽

Rare Case ◽

Interleukin 17 ◽

Inflammatory Condition ◽

Biologic Drugs ◽

Drug Induced ◽

First Case ◽

Background: Psoriasis is a cutaneous inflammatory condition characterized by an altered turnover of keratinocytes leading to scaly patches. Secukinumab and ixekizumab are two biologic drugs inhibiting interleukin-17. Objective: We report the first case, according to Naranjo score, of a secukinumab-induced erectile dysfunction with severe plaque psoriasis that disappeared after switching to another anti IL17 drug (ixekizumab). Methods: A 45 years old man experienced erectile dysfunction during treatment with an anti-IL17. The adverse effect appeared after 60 days of treatment with secukinumab and rapidly disappeared after discontinuation of the drug. All necessary urologic exams were carried out. Re-administration of secukinumab, due to the exacerbation of psoriasis, caused the same sexual dysfunction after 60 days. Results: Switching to ixekizumab lead to a resolution of the erectile dysfunction and a complete skin clearance. Conclusion: We describe for the first time a sexual dysfunction possibly due to secukinumab and its resolution after the switch to another similar but different drug, highlighting the potential difference between anti-IL17A drugs.

Fatal Case of Vulvar Pyoderma Gangrenosum with Pulmonary Involvement: Case Presentation and Literature Review

Journal of Cutaneous Medicine and Surgery ◽

10.2310/7750.2014.13196 ◽

2014 ◽

Vol 18 (6) ◽

pp. 424-429 ◽

Cited By ~ 8

Author(s):

Joshua M. Mercer ◽

Paul Kuzel ◽

Muhammad N. Mahmood ◽

Alain Brassard

Keyword(s):

Literature Review ◽

Pyoderma Gangrenosum ◽

Rare Case ◽

Fatal Case ◽

Pulmonary Involvement ◽

Review Of The Literature ◽

Treatment Resistant ◽

Case Presentation ◽

First Case ◽

Systemic Therapies

Introduction: We report a case of a 61-year-old woman with locally destructive vulvar pyoderma gangrenosum (PG) with pulmonary involvement who was refractory to numerous systemic therapies and developed complications resulting in her demise. Objective: To report a rare case of treatment-resistant vulvar PG with pulmonary involvement that proved to be fatal. Methods: PubMed was used to search for other reports that discuss PG, or more specifically perigenital PG, with pulmonary involvement. Results and Conclusion: A thorough review of the literature revealed 33 cases of PG with pulmonary involvement, with only 4 involving the perigenital region. We report the second case of a female with vulvar PG and pulmonary involvement. In contrast to the first case described, our patient did not respond to systemic therapy, and, ultimately, her disease was fatal. It is hoped that with continued documentation of this rare and potentially lethal presentation of PG, physicians will determine more effective treatments.

A rare case of pharyngeal perforation and expectoration of an entire anterior cervical fixation construct

Journal of Neurosurgery Spine ◽

10.3171/2016.10.spine16560 ◽

2017 ◽

Vol 26 (5) ◽

pp. 560-566 ◽

Cited By ~ 11

Author(s):

Syed A. Quadri ◽

John Capua ◽

Vivek Ramakrishnan ◽

Raed Sweiss ◽

Marc Cabanne ◽

...

Keyword(s):

Posterior Wall ◽

Anterior Fusion ◽

Pharyngeal Wall ◽

First Case ◽

Signal Change ◽

Pharyngeal Perforation ◽

Grade Ii ◽

Vertebral Bodies ◽

Esophageal Perforations

Anterior cervical discectomy and fusion (ACDF) is a very common surgery performed globally. Although a few cases of expectorating screws or extrusion of screws into the gastrointestinal tract through esophageal perforations have previously been reported, there has not been a case reporting pharyngeal perforation and entire cervical construct extrusion in the literature to date. In this report the authors present the first case involving the extrusion of an entire cervical construct via a tear in the posterior pharyngeal wall. An 81-year-old woman presented to the emergency department (ED) with a complaint of significant cervical pain 5 days after a fall due to a syncopal event. Radiological findings showed severe anterior subluxation of C-2 on C-3 with no spinal cord signal change noted. She underwent ACDF at the C2–3 level utilizing a polyetheretherketone (PEEK) cage, allograft, autograft, and a nontranslational plate with a locking apparatus and expanding screws. The screw placement was satisfactory on postoperative radiography and the Grade II spondylolisthesis of C-2 on C-3 was reduced appropriately with the surgery. The postoperative radiographs obtained demonstrated good instrumentation placement. Three and a half years later the patient returned to the ED having expectorated the entire anterior cervical construct. A CT scan demonstrated the C-2 and C-3 vertebral bodies to be fused posteriorly with an anterior erosive defect within the vertebral bodies and the anterior fusion hardware at the C2–3 level no longer identified. The fiberoptic laryngoscopy demonstrated a 1 × 1 cm area over the importation of the hypopharynx, above the glotic area. The Gastrografin swallowing test ruled out any esophageal tear or fistula and confirmed the presence of a large ulcer on the posterior wall of the oropharynx. To the best of the authors' knowledge, this is the first ever reported case of a tear in the posterior pharyngeal wall along with extrusion of the entire cervical construct after ACDF. This case demonstrates a rare but potentially serious complication of ACDF. Based on the available literature, each case requires separate and distinct treatment from the others.

Incidental para-ureteral aggressive angiomyxoma: a rare case report and literature review

BMC Urology ◽

10.1186/s12894-020-00755-7 ◽

2020 ◽

Vol 20 (1) ◽

Author(s):

Ming Liu ◽

Ting-Shuai Zhai ◽

Xiao-Feng Zhao ◽

Li-Jin Feng ◽

Xin-Sheng Lyu ◽

...

Keyword(s):

Literature Review ◽

Rare Case ◽

Reproductive Age ◽

Aggressive Angiomyxoma ◽

Case Presentation ◽

Left Ureter ◽

First Case ◽

Rare Case Report

Abstract Background Aggressive angiomyxoma (AA) is a rare tumor that typically occurs in the pelvis and perineum, most commonly in women of reproductive age. However, no para-ureteral AA has been reported according to the literature. Case presentation We herein describe the first case of para-ureteral AA. A 62-year-old male presented to our institute in March 2017 with a para-ureteral mass that was 15 mm in diameter incidentally. No symptom was observed and laboratory analysis was unremarkable. Magnetic resonance and computed tomography imaging showed a non-enhancing mass abutting the left ureter without causing obstruction. Laparoscopic resection of the mass was performed without injury to the ureter. Pathologic and immunohistochemical results were consistent with AA. Till now, no recurrence was noticed. Conclusions We reported a rare case of para-ureteral AA, along with a literature review. Early diagnosis, proper surgical plan and long-term close follow-up is recommended for its high risk of recurrence and malignant potential.