Comparison of the Sex Hormones’ Serum Level in Women With Recurrent Aphthous Stomatitis and Healthy Population: A Cross-Sectional Study

Abstract Background:In this study, we aimed to evaluate the sex hormonal serum level in patients with recurrent aphthous stomatitis and compare them with healthy participants.Methods:This cross-sectional study was done on patients with recurrent aphthous stomatitis who had referred to Shiraz Dental Faculty, Oral and Maxillofacial Medicine Department during 2018-2019. The non -menopause women with recurrence of at least 3 lesions per year were enrolled in this study.The mean serum level of FSH, LH, PRL (prolactin), testosterone, DHT (Dihydrotestosterone), DHEA-S (Dehydroepiandrosterone sulfate), estradiol and progesterone of 30 participants in each group of case and control were measured and compared. The data were analyzed by SPSS version 18 and independent T-test, Mann-Whitney U test, Spearman’s correlation coefficient test, Chi-square test and Fisher’s test.Results: The mean serum level of DHEA-S in patients with recurrent aphthous stomatitis (RAS) was significantly lower than the control group (p value=0.002). In addition to DHEA-S, the mean serum level of testosterone was lower in the evaluation group although this difference was not significant (p value=0.057).Considering the effect of age on the mean serum level of sex hormones, our results revealed that only DHEA-S mean serum level was decreased by increasing the age of participants in patients with RAS (p value=0.018).The number of participants with abnormal range of testosterone (p value<0.0001) and progesterone (p value=0.037) serum level was significantly more in patients with RAS. The frequency of RAS in a year did not show a significant relationship with the serum level of the evaluated hormones.Conclusion: The patients with RAS had a lower serum level of DHEA-S. The mean serum level of testosterone and progesterone was significantly abnormal in RAS patients.

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Comparison of the sex hormones’ serum level in women with recurrent aphthous stomatitis and healthy population: a cross-sectional study

BMC Oral Health ◽

10.1186/s12903-021-01812-9 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Fatemeh Lavaee ◽

Zahra Ranjbar ◽

Mina Jalalian ◽

Mohammad Amin Amiri

Keyword(s):

Serum Level ◽

Sex Hormones ◽

Cross Sectional Study ◽

Recurrent Aphthous Stomatitis ◽

Aphthous Stomatitis ◽

Control Group ◽

Healthy Population ◽

Sectional Study ◽

Cross Sectional ◽

The Mean

Abstract Background In this study, we aimed to evaluate the sex hormonal serum level in patients with recurrent aphthous stomatitis and compare them with healthy participants. Methods This cross-sectional study was done on patients with recurrent aphthous stomatitis who had referred to Shiraz Dental Faculty, Oral and Maxillofacial Medicine Department during 2018–2019. The non -menopause women with recurrence of at least 3 lesions per year were enrolled in this study. The mean serum level of FSH, LH, PRL (prolactin), testosterone, DHT (Dihydrotestosterone), DHEA-S (Dehydroepiandrosterone sulfate), estradiol and progesterone of 30 participants in each group of case and control were measured and compared. The data were analyzed by SPSS version 18 and independent T-test, Mann–Whitney U test, Spearman’s correlation coefficient test, Chi-square test and Fisher’s test. Results The mean serum level of DHEA-S in patients with recurrent aphthous stomatitis (RAS) was significantly lower than the control group (p value = 0.02). In addition to DHEA-S, the mean serum level of testosterone was lower in the evaluation group although this difference was not significant (p value = 0.057). Considering the effect of age on the mean serum level of sex hormones, our results revealed that only DHEA-S mean serum level was decreased by increasing the age of participants in patients with RAS (p value = 0.018). The number of participants with abnormal range of testosterone (p value < 0.0001) and progesterone (p value = 0.037) serum level was significantly more in patients with RAS. The frequency of RAS in a year did not show a significant relationship with the serum level of the evaluated hormones. Conclusion The patients with RAS had a lower serum level of DHEA-S. The mean serum level of testosterone and progesterone was significantly abnormal in RAS patients.

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Effect of Medialization of the Trochlear Groove and Lateralization of the Tibial Tubercle on TT-TG Distance: A Cross-sectional Study of Dysplastic and Nondysplastic Knees

The American Journal of Sports Medicine ◽

10.1177/0363546520987819 ◽

2021 ◽

pp. 036354652098781

Author(s):

Mathias Paiva ◽

Lars Blønd ◽

Per Hölmich ◽

Kristoffer Weisskirchner Barfod

Keyword(s):

Trochlear Dysplasia ◽

Cross Sectional Study ◽

Magnetic Resonance Images ◽

Tibial Tubercle ◽

Control Group ◽

Trochlear Groove ◽

Sectional Study ◽

Cross Sectional ◽

Mean Values ◽

The Mean

Background: Tibial tubercle–trochlear groove (TT-TG) distance is often used as a measure of lateralization of the TT and is important for surgical planning. Purpose: To investigate if increased TT-TG distance measured on axial magnetic resonance images is due to lateralization of the TT or medialization of the TG. Study Design: Cross-sectional study; Level of evidence, 3. Methods: A total of 84 knees (28 normal [NK], 28 with trochlear dysplasia [TD], and 28 with patellar dislocation without TD [PD]) were examined. The medial border of the posterior cruciate ligament (PCL) was chosen as the central anatomic landmark. The distance from the TT to PCL (TT-PCL) was measured to examine the lateralization of the TT. The distance from the TG to the PCL (TG-PCL) was measured to examine the medialization of the TG. Between-group differences were investigated by use of 1-way analysis of variance. Results: The mean values for TT-TG distance were 8.7 ± 3.6 mm for NK, 12.1 ± 6.0 mm for PD, and 16.7 ± 4.3 mm in the TD group ( P < .01). The mean values for TT-PCL distance were 18.5 ± 3.6 mm for NK, 18.5 ± 4.5 mm for PD, and 21.2 ± 4.2 mm in the TD group ( P = .03). The mean values for TG-PCL distance were 9.6 ± 3.0 mm for NK, 7.1 ± 3.4 mm for PD, and 5.1 ± 3.3 mm in the dysplastic group ( P < .01). Conclusion: The present results indicate that increased TT-TG distance is due to medialization of the TG and not lateralization of the TT. Knees with TD had increased TT-TG distance compared with the knees of the control group and the knees with PD. The TT-PCL distance did not differ significantly between groups, whereas the TG-PCL distance declined with increased TT-TG.

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Tooth Loss and Its Association With Frequency of Pregnancy: A Cross-Sectional Study Among Yemeni Women

10.21203/rs.3.rs-147421/v1 ◽

2021 ◽

Author(s):

Anas Shamala ◽

Ebtesam Al-Maimooni ◽

Salsbeel Al-Matari ◽

Ryhana Hiyat ◽

Mohammed Al-wesabi ◽

...

Keyword(s):

Oral Hygiene ◽

Tooth Loss ◽

Cross Sectional Study ◽

P Value ◽

Sectional Study ◽

Cross Sectional ◽

Khat Chewing ◽

Number Of Children ◽

Hygiene Practices ◽

The Mean

Abstract Backgrounds: The present study sought to assess tooth loss and oral hygiene practices among a sample of Yemeni women in association with giving births (parity).Subjects and Methods: This cross-sectional study included a sample of 644 Yemeni women. They were interviewed to gather socio-demographic (age, education, number of children) and behavioral data (oral hygiene practices, khat chewing and smoking). Additionally, they were examined clinically to assess number of tooth loss. Data were analyzed using SPSS with a P-value < 0.05 was considered statistically significant. Results: The participating women aged between 16 and 51 years. Only one fifth of the sample reported brushing their teeth regularly (i.e, at least once a day), and around 36.8% reported using dental aids occasionally. Additionally, 52% and 21% of the sample reported they were khat chewers and smokers, respectively. The mean number of tooth loss was 4.7. The mean number of children was 4.15, with approximately 54% of the participating women had more than 3 children. The results of the logistic regression revealed a significant association between number of children and tooth loss. Conclusion: Yemeni women had poor oral hygiene practices and high prevalence of tooth loss increased proportionally with the increased number of children. This emphasizes the importance of an effective oral hygiene motivation and health education among female patients during pregnancy periods.

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Cross-sectional study to compare the biochemical parameters in low normal versus high normal plasma glucose levels in euglycemic individuals

International Journal of Advances in Medicine ◽

10.18203/2349-3933.ijam20202117 ◽

2020 ◽

Vol 7 (6) ◽

pp. 997

Author(s):

Dharmendra Jhavar ◽

Neha Kirti ◽

Sumit Kumar Vishwakarma ◽

Umesh Kumar Chandra ◽

Vinod Verma

Keyword(s):

Uric Acid ◽

Total Cholesterol ◽

General Medicine ◽

Cross Sectional Study ◽

Normal Group ◽

P Value ◽

Sectional Study ◽

Cross Sectional ◽

The Mean ◽

The Difference

Background: Since a long time ago, the experts have realized that determination of cut-off point for diagnosing diabetes will be revised over time with the lower blood glucose level as the more sensitive diagnosis for detecting the occurring complication and biochemical changes.Methods: This cross sectional study was carried out in the department of medicine, M.G.M. Medical College and M.Y. Hospital Indore from July, 2016 to August, 2017 in 200 individuals and patients having euglycemic status attending General Medicine OPD.Results: In the low and high normal group 2 (2.0%) and 8 (8.0%) were having abnormal total cholesterol (TC) level respectively. The mean total cholesterol in the low normal group was 117.16±26.94mg/dl and it was 154.74±28.38mg/dl in the high normal group. The difference was found to be statistically significant (p value 0.000). In the low and high normal group, 4 (4.0%) and 17 (17.0%) were having abnormal triglyceride (TG) levels respectively. The mean TG levels in the low and high normal group were 96.93±22.64mg/dl and 110.55±32.37mg/dl respectively. The difference was found to be statistically significant (p value 0.001). In the low and high normal group, 6 (6.0%) and 14 (14.0%) patient was having abnormal uric acid levels respectively. The mean uric acid levels in the low and high normal group was 4.88±1.10mg/dl and 5.31±1.31mg/dl respectively. The difference was found to be statistically significant (p value 0.013).Conclusions: Higher levels of Cholesterol and Triglycerides were found more commonly in high normal euglycemic group compared to low normal euglycemic group. Mean cholesterol and mean triglyceride levels were higher in high normal euglycemic group.

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Validation of the HADS and PSS‐10 and a cross‐sectional study of psychological status in patients with recurrent aphthous stomatitis

Journal of Oral Pathology and Medicine ◽

10.1111/jop.12991 ◽

2020 ◽

Vol 49 (3) ◽

pp. 260-270 ◽

Cited By ~ 3

Author(s):

Paswach Wiriyakijja ◽

Stephen Porter ◽

Stefano Fedele ◽

Tim Hodgson ◽

Roddy McMillan ◽

...

Keyword(s):

Cross Sectional Study ◽

Recurrent Aphthous Stomatitis ◽

Aphthous Stomatitis ◽

Psychological Status ◽

Sectional Study ◽

Cross Sectional

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Lifestyle of students at Tehran University of Medical Sciences during Corona Epidemic: A cross-sectional study

Iranian Journal Of Health Sciences ◽

10.18502/jhs.v9i3.7308 ◽

2021 ◽

Author(s):

Fatemeh Rahimi ◽

Elahe Alamdar ◽

Hengame Sadat Seyed Mirnasab ◽

Somaieh Borjalilu ◽

Mahnaz Pouresmaeil ◽

...

Keyword(s):

Spiritual Growth ◽

Cross Sectional Study ◽

Demographic Variables ◽

P Value ◽

Sectional Study ◽

Medical Sciences ◽

Cross Sectional ◽

Health Promoting ◽

The Mean ◽

Health Promoting Lifestyle

Background and purpose: There is concern that students may have an unhealthy lifestyle as a result of changes that occurred during corona conditions, so this study aimed to determine the status of the lifestyle and its relationship with the demographic characteristics of postgraduate students during the corona span. Material and Methods: This cross-sectional study was conducted at Tehran University of Medical Sciences in 2020. The link to the online Health-Promoting Lifestyle Questionnaire Profile2 was sent to conduct the research. To examine the relationships between the mean scores of health-promoting lifestyle and different variables, an independent samples t-test was applied in the case of dichotomous demographic variables (gender, education level, and income-generating activity), while one-way analysis of variance test was used to evaluate the multilevel demographic variables (marital status, place of residence, and faculty). The Pearson correlation coefficient was also used for testing age. Results: The sample 240, (75.4%) were female and 145 of them, (60.4%) were single. The mean age of them was 32.21±7.45.45 years old. The lifestyle total score was 138.28± 21.18 at the average level. The highest score was related to spiritual growth (26.93±5.01), whereas the lowest score was reported on physical activity (16.92±5.17). The difference between the mean of health-promoting lifestyle was not significant in terms of demographic variables.According to the results, a statistically significant difference was observed between male and female students in the field of nutrition. Also, students were significantly different in the nutrition domain regarding students’ residence (p-value <0.05). Spiritual growth was significantly different among students in terms of marital status (p-value <0.05). Conclusion: Although the mean score of health-promoting lifestyle was not different from other studies, further studies are proposed to plan health interventions in accordance with epidemic conditions for students.

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Frequency of Stress, Anxiety and Depression in Patients with Alopecia Areata and Control Group Referring to Skin Clinics of Yazd City in 2017

Journal of Shahid Sadoughi University of Medical Sciences ◽

10.18502/ssu.v28i1.3132 ◽

2020 ◽

Author(s):

Mohammad Ebrahimzadeh Ardakani ◽

Ghasem Dastjerdi ◽

Sepideh Hasani

Keyword(s):

Alopecia Areata ◽

Cross Sectional Study ◽

Anxiety And Depression ◽

Control Group ◽

P Value ◽

Common Disease ◽

Depression Anxiety Stress Scale ◽

Cross Sectional ◽

The Mean ◽

Yazd City

Introduction: Alopecia areata is a fairly common disease characterized by patchy aria of hair loss. The role of psychological factors in the occurrence of alopecia areata has long been discussed. The present study was conducted to determine the frequency of stress and anxiety and depression in the patients with alopecia areata in Yazd City in 2017. Methods: This study was a cross-sectional study and 50 patients with alopecia areata in Yazd were compared with 50 in the control group in the year 2016. Sampling method was a census and variables, including sex, age, education level, duration of lesion, frequency of relapse, and location of the disease were collected and recorded using a questionnaire. The depression anxiety stress-scale (DASS) (Dass11) questionnaire was used for scoring anxiety, stress and depression. For analyzing the collected data were entered into SPSS version 13. Results: The results of the study showed that the mean age of the participants in the study was 30.27 ± 8.7, the mean duration of lesion was 23.5±53.52 months and the mean recurrence rate was 1.4±2.2. From 100 participants in the study, 36 (36%) were women and 64 (64%) were men. The mean score of depression (6.8 vs 4.6), anxiety score (6.08 vs 3.5) and stress score (10.06 vs 8.06) were found to be significantly different between the two groups. Also, in women and in the age range of 17-29 years, the mean of depression and anxiety scores was significantly different in the two groups (P-value <0.05). Conclusion: According to results, it can be concluded that the frequency of depression, anxiety and stress in the patients with alopecia areata is significantly more than the control group.

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Is type 1 diabetes mellitus associated with ABO & Rh blood groups? A cross-sectional study

Iranian Journal of Pediatric Hematology & Oncology ◽

10.18502/ijpho.v12i1.8362 ◽

2022 ◽

Author(s):

Mahtab Ordooei ◽

Nasim Namiranian ◽

Saeedeh Jam-Ashkezari ◽

Hadi Jalali ◽

Azam Golzar

Keyword(s):

Diabetes Mellitus ◽

Type 1 Diabetes ◽

Blood Group ◽

Cross Sectional Study ◽

Blood Groups ◽

P Value ◽

Sectional Study ◽

Cross Sectional ◽

The Mean

Background: This study was conducted to determine whether type 1 diabetes mellitus (T1DM) is associated with ABO & Rhesus (Rh) blood groups. Materials and Methods: This analytical cross sectional study was carried out on 77 patients suffering from T1DM and 96 healthy children less than 18 years old referring to Yazd Diabetes Research Center from April 2018 to May 2019. The ABO blood group and Rh factor in both groups were determined. Fasting blood sugar (FBS) and hemoglobin A1C (HbA1c) were measured at baseline, 12 weeks, and 24 weeks in these patients, and the mean of FBS and HbA1C in three-time assessments were considered as the FBS and HbA1C variables. The statistical analysis was performed by SPSS software version 22. Results: About 46.8% in T1DM and 36.5% in the control groups were male. There was a significant difference between groups regarding blood groups (p-value: 0.042). Although the frequency of B+ was 33.8% and 19.8% in the T1DM and controls, respectively, AB+ and O+ were more prevalent in the controls. The mean of FBS was significantly different between groups (p-value: 0.023). Conclusions: The findings revealed that patients with blood group B are more likely to develop T1DM whereas those with blood group O showed a lower tendency towards diabetes.

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A study of blood pressure in school children between the age of 6-12 years in Chennai, India: a cross sectional study

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20174758 ◽

2017 ◽

Vol 4 (6) ◽

pp. 2205

Author(s):

Madhivanan S. ◽

Harikrishnan E. ◽

Kumarasamy K.

Keyword(s):

Blood Pressure ◽

Clinical Examination ◽

Economic Status ◽

Blood Pressure Measurement ◽

Cross Sectional Study ◽

P Value ◽

Sectional Study ◽

Cross Sectional ◽

Significant Difference ◽

The Mean

Background: Blood pressure measurements in childhood are an important clinical examination. Present study was done to evaluate the normal range of blood pressure (BP) in children aged 6-12 years and to find its relationship with regard to age, sex, height and weight criteria and comparing the values with the available standards.Methods: This prospective cross-sectional study was done in primary and middle schools of Chennai from January 2016 to May 2017. Three readings of blood pressure were recorded for each subject and were correlated with age, gender, socioeconomic status and anthropometry. Data was analysed on SPSS 20.0. P value of <0.05 was considered significantResults: A total of 2002 children (1026 boys, 976 girls) of age between 6-12 years were examined over 18 months. There was an upward trend in both systolic (r = 0.437, P<0.001) and diastolic BP (r = 0.386, P <0.001) with age. There was no statistically significant difference in mean systolic and diastolic BP with gender (P = 0.10), weight (P = 0.10) and height (P = 0.10). There was a statistically significant difference between the mean systolic and diastolic BP between low and high socio-economic groups (P <0.0001). The proportion of children with hypertension was 9.54% with a slight female preponderance.Conclusions: Blood pressure measurement in children is pivotal in clinical examination. It shows a linear relationship with age and varies across socio-economic status. Periodic recording of BP would enable identify hypertension at an early age.

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