Factors affecting birthweight decline in recent Japan based on birth certificates

2020 ◽  
Author(s):  
Noriko Kato ◽  
Catherine Sauvaget ◽  
Honami Yoshida ◽  
Tetsuji Yokoyama ◽  
Nobuo Yoshiike
Keyword(s):  
Birth Order ◽  
Gestational Age ◽  
Low Birthweight ◽  
Maternal Diet ◽  
Linear Regression Analysis ◽  
Birth Certificate ◽  
Vital Statistics ◽  
Birth Certificates ◽  
Maternal Body Mass Index ◽  
Multiple Gestations

Abstract Background: Birthweight has been declining consistently for >30 years in Japan. This rapid rise in low birthweight in infants is the worst among the Organization for Economic Co-operation and Development countries.Objective: To contribute to the literature and provide new information to clarify the risk factors associated with birthweight decline in Japan.Methods: We used population-based birth certificate data from vital statistics records with prior permission and retrieved 40,968,266 birth certificates of neonates born between 1980 and 2004 to analyze time trends using linear regression analysis for examining whether the decline in birthweight could be explained by obstetrical variables such as gestational age and multiple gestations.Results: From 1980 to 2004, we observed a decline in mean birthweight with a yearly effect of -8.07 g, which became steeper after 1985, persisted until 1999, and plateaued thereafter. After adjusting for gestational age, neonatal gender, birth order, multiple gestations, and fathers’ age, the yearly effect between 1980 and 2004 reduced to -5.13 g. Conclusion: Recent decreases in birthweight among Japanese neonates were not explained fully by trends in gestational age, neonatal gender, birth order, multiple gestations, and fathers’ age. Thus, additional factors such as pre-pregnancy maternal body mass index and maternal diet should be considered.

scholarly journals Factors associated with birthweight decline in Japan (1980–2004)

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Noriko Kato ◽  
Catherine Sauvaget ◽  
Honami Yoshida ◽  
Tetsuji Yokoyama ◽  
Nobuo Yoshiike
Keyword(s):  
Birth Order ◽  
Gestational Age ◽  
Low Birthweight ◽  
Maternal Diet ◽  
Linear Regression Analysis ◽  
Birth Certificate ◽  
Vital Statistics ◽  
Birth Certificates ◽  
Maternal Body Mass Index ◽  
Multiple Gestations

Abstract Background Birthweight has been declining consistently for more than 30 years in Japan. This rapid rise in low birthweight is one of the worst among the countries of the Organization for Economic Co-operation and Development. We examined potential determinants of birthweight decline in Japan. Methods We used population-based birth certificate data from vital statistics records and retrieved 40,968,266 birth certificates of neonates born between 1980 and 2004. We analyzed time trends using linear regression analysis in examining whether the decline in birthweight could be explained by obstetrical variables such as gestational age and multiple gestations. Results From 1980 to 2004, we observed a decline in mean birthweight with a yearly effect of − 8.07 g, which became steeper after 1985, persisted until 1999, and plateaued thereafter. After adjusting for gestational age, gender, birth order, multiple gestations, and fathers’ age, the yearly effect between 1980 and 2004 persisted at − 5.13 g. Conclusion Recent decreases in birthweight among Japanese neonates were not fully explained by trends in gestational age, gender, birth order, multiple gestations, and fathers’ age. Thus, additional factors such as pre-pregnancy maternal body mass index (BMI) and maternal diet should be considered. Reducing the rate of induced deliveries and improving the BMI or diet of young women should be a public health priority.

scholarly journals Factors Affecting Birthweight Decline in Recent Japan Based on Birth Certificates

2020 ◽  
Author(s):  
Noriko Kato ◽  
Catherine Sauvaget ◽  
Honami Yoshida ◽  
Tetsuji Yokoyama ◽  
Nobuo Yoshiike
Keyword(s):  
Birth Order ◽  
Gestational Age ◽  
Maternal Diet ◽  
Linear Regression Analysis ◽  
Vital Statistics ◽  
Birth Certificates ◽  
Factors Affecting ◽  
New Information ◽  
Multivariable Linear Regression Analysis ◽  
Birth Records

Abstract Background:Birthweight is declining consistently for more than 30 years in Japan. Rapid rise in low birth weight infant counts one of the worst among OECD countries.Objective: To add new information for clarifying the factors associated with the decline in birthweight in Japan.Methods: Government vital statistics records were used under permission. 40,968,266 birth records born between 1980 and 2004 were analyzed. Multivariable linear regression analysis was used to examine whether the decline in the birthweight could be explained by obstetrical variables such as gestational age and plurality.Results: From 1980 to 2004, we observed a decline in mean birthweight with yearly effect of -8.07g, which got steeper after 1985 and persisted until 1999, and plateaued thereafter. After adjustment for gestational age, neonatal gender, birth order, plurality, father age, yearly effect became -5.13g, between 1980 and 2004. Conclusion：Recent decreases in birthweight among Japanese neonates were not fully explained by trends of gestational age, sex, birth order, plurality and father age. We should consider additional factors such as pre-pregnant maternal BMI and maternal diet.

scholarly journals Impact of maternal age on birthweight in frozen embryo transfer cycles: an analysis including 12565 singleton newborns

2020 ◽  
Author(s):  
Zhexin Ni ◽  
Shuai Sun ◽  
Wen Cheng ◽  
Jin Yu ◽  
Dongxia Zhai ◽  
...  
Keyword(s):  
Linear Regression ◽  
Embryo Transfer ◽  
Gestational Age ◽  
Maternal Age ◽  
Linear Regression Analysis ◽  
Frozen Embryo Transfer ◽  
Maternal Body Mass Index ◽  
Significant Difference ◽  
Z Scores ◽  
The Relationship

Abstract Background Previous studies have investigated the effect of maternal age on assisted reproductive technology (ART) success rates. However, little is known about the relationship between maternal age and neonatal birthweight in frozen embryo transfer (FET) cycles. Does maternal age have an impact on singleton birthweight in FET cycles?Methods This retrospective study was conducted at a tertiary care centre, involving singleton live births born to women undergoing frozen-thawed embryo transfer during the period from January 2010 to December 2017. A total of 12565 women who fulfilled the inclusion criteria were enrolled and were grouped into four groups according to the maternal age: <30, 30–34, 35–39, and ≥ 40 years old. Maternal age between 30 and 34 years old was taken as a reference group. Singleton birthweight was the key outcome measure. A multivariable linear regression analysis was conducted to reveal the relationship between maternal age and neonatal birthweight with controlling for a number of potential confounders.Results A modest decrease but no significant difference in birthweight and gestational age- and gender-adjusted birthweight (Z-scores) was observed in maternal age over 35 years old as compared with group with 30–34 years old. Further, multiple linear regression analyses indicated that maternal body mass index (BMI), embryo developmental stage at transfer, parity, number of embryos transferred, FET endometrial preparation, endometrial thickness, gestational age and newborn gender were all independent predictors of neonatal birthweight.Conclusion Grouping with different maternal age was not associated with mean birthweight and Z-scores of singletons resulting from FET.

Birth order, interpregnancy interval and birth outcomes among Filipino infants

1994 ◽  
Vol 26 (2) ◽  
pp. 243-259 ◽  
Author(s):  
Jane E. Miller
Keyword(s):  
Birth Order ◽  
Neonatal Mortality ◽  
Birth Outcomes ◽  
Gestational Age ◽  
Low Birthweight ◽  
Short Interval ◽  
Family Health ◽  
The Philippines ◽  
Interpregnancy Interval ◽  
High Birth Order

SummaryThis study examines the effects of birth order and interpregnancy interval on birthweight, gestational age, weight-for-gestational age, infant length, and weight-for-length in a sample of 2063 births from a longitudinal study in the Philippines. First births are the most disadvantaged of any birth order/spacing group. The risks associated with short intervals (<6 months) and high birth order (fifth or higher) are confined to infants who have both attributes; there is no excess risk associated with short previous intervals among lower-order infants, nor for high birth order infants conceived after longer intervals. This pattern is observed for all five birth outcomes and neonatal mortality, and persists in models that control for mother's age, education, smoking, family health history and nutritional status. Since fewer than 2% of births are both short interval and high birth order, the potential reduction in the incidence of low birthweight or neonatal mortality from avoiding this category of high-risk births is quite small (1–2%).

PENENTUAN DAERAH PRIORITAS PELAYANAN AKTA KELAHIRAN DENGAN METODE K-NN DAN K-MEANS

2020 ◽  
Vol 17 (1) ◽  
pp. 319-328
Author(s):  
Ade Muchlis Maulana Anwar ◽  
Prihastuti Harsani ◽  
Aries Maesya
Keyword(s):  
Nearest Neighbor ◽  
Information Gain ◽  
Birth Certificate ◽  
Population Data ◽  
Community Services ◽  
Birth Certificates ◽  
Similar Data ◽  
K Nearest Neighbor ◽  
Civil Registration ◽  
The Family

Population Data is individual data or aggregate data that is structured as a result of Population Registration and Civil Registration activities. Birth Certificate is a Civil Registration Deed as a result of recording the birth event of a baby whose birth is reported to be registered on the Family Card and given a Population Identification Number (NIK) as a basis for obtaining other community services. From the total number of integrated birth certificate reporting for the 2018 Population Administration Information System (SIAK) totaling 570,637 there were 503,946 reported late and only 66,691 were reported publicly. Clustering is a method used to classify data that is similar to others in one group or similar data to other groups. K-Nearest Neighbor is a method for classifying objects based on learning data that is the closest distance to the test data. k-means is a method used to divide a number of objects into groups based on existing categories by looking at the midpoint. In data mining preprocesses, data is cleaned by filling in the blank data with the most dominating data, and selecting attributes using the information gain method. Based on the k-nearest neighbor method to predict delays in reporting and the k-means method to classify priority areas of service with 10,000 birth certificate data on birth certificates in 2019 that have good enough performance to produce predictions with an accuracy of 74.00% and with K = 2 on k-means produces a index davies bouldin of 1,179.

scholarly journals Birthweight DNA methylation signatures in infant saliva

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Chiara Moccia ◽  
Maja Popovic ◽  
Elena Isaevska ◽  
Valentina Fiano ◽  
Morena Trevisan ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Cord Blood ◽  
Gestational Age ◽  
Low Birthweight ◽  
Continuous Variable ◽  
Linear Regression Models ◽  
Association Analyses ◽  
Cpg Sites ◽  
Adverse Health Outcomes ◽  
The Look

Abstract Background Low birthweight has been repeatedly associated with long-term adverse health outcomes and many non-communicable diseases. Our aim was to look-up cord blood birthweight-associated CpG sites identified by the PACE Consortium in infant saliva, and to explore saliva-specific DNA methylation signatures of birthweight. Methods DNA methylation was assessed using Infinium HumanMethylation450K array in 135 saliva samples collected from children of the NINFEA birth cohort at an average age of 10.8 (range 7–17) months. The association analyses between birthweight and DNA methylation variations were carried out using robust linear regression models both in the exploratory EWAS analyses and in the look-up of the PACE findings in infant saliva. Results None of the cord blood birthweight-associated CpGs identified by the PACE Consortium was associated with birthweight when analysed in infant saliva. In saliva EWAS analyses, considering a false discovery rate p-values < 0.05, birthweight as continuous variable was associated with DNA methylation in 44 CpG sites; being born small for gestational age (SGA, lower 10th percentile of birthweight for gestational age according to WHO reference charts) was associated with DNA methylation in 44 CpGs, with only one overlapping CpG between the two analyses. Despite no overlap with PACE results at the CpG level, two of the top saliva birthweight CpGs mapped at genes associated with birthweight with the same direction of the effect also in the PACE Consortium (MACROD1 and RPTOR). Conclusion Our study provides an indication of the birthweight and SGA epigenetic salivary signatures in children around 10 months of age. DNA methylation signatures in cord blood may not be comparable with saliva DNA methylation signatures at about 10 months of age, suggesting that the birthweight epigenetic marks are likely time and tissue specific.

Categories of intrauterine growth retardation

1993 ◽  
Vol 5 (4) ◽  
pp. 203-212 ◽  
Author(s):  
Roger A Fay ◽  
David A Ellwood
Keyword(s):  
Soft Tissue ◽  
Fetal Growth ◽  
Gestational Age ◽  
Growth Retardation ◽  
Large Scale ◽  
Intrauterine Growth Retardation ◽  
Low Birthweight ◽  
Ponderal Index ◽  
Intrauterine Growth ◽  
Different Types

Originally all low birthweight infants were considered to be premature. When prematurity was redefined in terms of gestational age (SGA) and not preterm. With the large scale collection of obstetric data the distributions of birthweight at different gestational ages were described and from these, infants who were SGA could be defined. SGA became synonymous with terms such as growth retardation, but it soon became appearent that the two were not necessarily interchangeable. Scott and Usher found that it was the degree of soft tissue wasting rather than birthweight that related to poor perinatal outcome. Miller and Hassanein stated that: “birthweight by itself is not a valid measure of fetal growth impairment”. They used Rorher’s Ponderal Index (weight (g) × 100/length (cm)) to diagnose the malnourished or excessively wasted infants with reduced soft tissue mass. Most studies of intrauterine growth retardation (IUGR) still use low birthweight for gestational age centile as their only definition of IUGR or only study infants who have a low birthweight. Altman and Hytten expressed disquiet about this definition and stated: “There is now an urgent need to establish true measures of fetal growth from which deviations indicating genuine growth retardation can be derived” and that “it is particularly important that some reliable measures of outcome should be established”. In large series of term deliveries published recently, two groups of IUGR infants with different growth patterens have been identified. These studies confirm that birthweight alone is inadequate to define the different types of IUGR. They established that low Ponderal Index (PI) is a measure of IUGR associated with an increased incidence of perinatal problems and that it is time to re-evaluate IUGR in terms of the different types of aberrant fetal growth.

scholarly journals Birth and Fetal Death Records and Environmental Exposures: Promising Data Elements for Environmental Public Health Tracking of Reproductive Outcomes

2009 ◽  
Vol 124 (6) ◽  
pp. 825-830 ◽  
Author(s):  
Edward Fitzgerald ◽  
Daniel Wartenberg ◽  
W. Douglas Thompson ◽  
Allison Houston
Keyword(s):  
Public Health ◽  
Fetal Death ◽  
Birth Certificate ◽  
Environmental Exposures ◽  
Birth Certificates ◽  
Parental Occupation ◽  
Environmental Public Health ◽  
Health Tracking ◽  
Environmental Public Health Tracking ◽  
Data Elements

Objectives. We inventoried and reviewed the birth and fetal death certificates of all 50 U.S. states to identify nonstandard data items that are environmentally relevant, inexpensive to collect, and might enhance environmental public health tracking. Methods. We obtained online or requested by mail or telephone the birth certificate and fetal death record forms or formats from each state. Every state data element was compared to the 2003 standards promulgated by the National Center for Health Statistics to identify any items that are not included on the standard. We then evaluated these items for their utility in environmentally related analyses. Results. We found three data fields of potential interest. First, although every state included residence of mother at time of delivery on the birth certificate, only four states collected information on how long the mother had lived there. This item may be useful in that it could be used to assess and reduce misclassification of environmental exposures among women during pregnancy. Second, we found that father's address was listed on the birth certificates of eight states. This data field may be useful for defining paternal environmental exposures, especially in cases where the parents do not live together. Third, parental occupation was listed on the birth certificates of 15 states and may be useful for defining parental workplace exposures. Our findings were similar for fetal death records. Conclusion. If these data elements are accurate and well-reported, their addition to birth, fetal death, and other health records may aid in environmental public health tracking.

Do Cash Transfers Improve Birth Outcomes? Evidence from Matched Vital Statistics, and Program and Social Security Data

2016 ◽  
Vol 8 (2) ◽  
pp. 1-43 ◽  
Author(s):  
Verónica Amarante ◽  
Marco Manacorda ◽  
Edward Miguel ◽  
Andrea Vigorito
Keyword(s):  
Social Security ◽  
Birth Outcomes ◽  
Low Birthweight ◽  
Maternal Nutrition ◽  
Vital Statistics ◽  
Cash Transfers ◽  
Gestational Length ◽  
Assistance Program ◽  
Intrauterine Growth ◽  
Key Driver

There is limited empirical evidence on whether cash transfers to poor pregnant women improve children's birth outcomes and potentially help weaken the cycle of intergenerational poverty. Using a unique array of program and social security administrative micro-data matched to longitudinal vital statistics in Uruguay, we estimate that participation in a generous social assistance program led to a sizable reduction in the incidence of low birthweight. The effect is due to faster intrauterine growth rather than longer gestational length. Our findings are consistent with improved maternal nutrition during pregnancy being a key driver of improved birthweight. (JEL I14, I32, I38, J13, J16, O15)

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