scholarly journals Replantation of Spinous Process-lamina Complex in the Treatment of Cervical Spine Tumor : Two Cases Report and Literature Review

2021 ◽  
Author(s):  
Xu Jiahui ◽  
Ma Bin ◽  
Wang Chenggang
Keyword(s):  
Spinous Process ◽  
Tumor Resection ◽  
Good Health ◽  
Structure And Function ◽  
Anatomical Structure ◽  
Spine Tumor ◽  
Posterior Element ◽  
Cervical Spine Tumor ◽  
And Function

Abstract Purpose: The primary aim of our study was to prove that the replantation of spinous process-lamina complex is beneficial to restore the anatomical structure and function of the spine, and to find if it can reduce postoperative complications.Methods: We report two cases of cervical intraspinal tumor, whose postoperative pathological diagnosis, Respectively, are Neurilemmoma and meningioma. They all underwent the resection and replantation of spinous process-lamina complex, in which the resected spinous process-lamina complex was replanted at the end of the procedure, allowing a complete reconstruction of the posterior element of the spinal canal. Results：After the surgery, the symptoms were relieved, and no dysfunction of upper limbs and sphincter was observed. The tumors were benign pathologically and were diagnosed as Neurilemmoma and meningioma. The patient recovered and at 6-month follow-up had no complaints and in good health.Conclusion: After tumor resection, the replantation of spinous process-lamina complex is beneficial to restore the anatomical structure and function of the spine.

Lung Structure And Function Relation In Elastase-Treated Rats: A Long-Term Follow Up Study

2012 ◽  
Author(s):  
Margit V. Szabari ◽  
Jozsef Tolnai ◽  
Balazs Maar ◽  
Harikrishnan Parameswaran ◽  
Elizabeth Bartolak-Suki ◽  
...  
Keyword(s):  
Structure And Function ◽  
Follow Up Study ◽  
Lung Structure ◽  
Long Term Follow Up ◽  
And Function ◽  
Function Relation

Ureteropelvic Junction: A Study of Its Anatomical Structure and Function

1999 ◽  
Vol 36 (2) ◽  
pp. 150-157 ◽  
Author(s):  
Ahmed Shafik ◽  
Al-Moatasem Al-Sherif
Keyword(s):  
Structure And Function ◽  
Anatomical Structure ◽  
Ureteropelvic Junction ◽  
And Function

scholarly journals HDL cholesterol efflux capacity is inversely associated with subclinical cardiovascular risk markers in young adults: The cardiovascular risk in Young Finns study

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Monika Hunjadi ◽  
Claudia Lamina ◽  
Patrick Kahler ◽  
Tamara Bernscherer ◽  
Jorma Viikari ◽  
...  
Keyword(s):  
Young Adults ◽  
Cardiovascular Risk ◽  
Cholesterol Efflux ◽  
Subclinical Atherosclerosis ◽  
Structure And Function ◽  
Risk Markers ◽  
Arterial Structure ◽  
And Function ◽  
Young Finns Study

Abstract The atherogenic process begins already in childhood and progresses to symptomatic condition with age. We investigated the association of cholesterol efflux capacity (CEC) and vascular markers of subclinical atherosclerosis in healthy, young adults. CEC was determined in 2282 participants of the Young Finns study using cAMP treated 3H-cholesterol-labeled J774 cells. The CEC was correlated to baseline and 6-year follow-up data of cardiovascular risk factors and ultrasound measurements of arterial structure and function. CEC was higher in women, correlated with total cholesterol, HDL-C, and apolipoprotein A-I, but not with LDL-C or apolipoprotein B. Compared to the lowest CEC quartile, the highest CEC quartile was significantly associated with high CRP levels and inversely associated with adiponectin. At baseline, high CEC was associated with decreased flow-mediated dilation (FMD) and carotid artery distensibility, as well as an increased Young's modulus of elasticity, indicating adverse changes in arterial structure, and function. The association reversed with follow-up FMD data, indicating the interaction of preclinical parameters over time. A higher CEC was directly associated with a lower risk of subclinical atherosclerosis at follow-up. In young and healthy subjects, CEC was associated with important lipid risk parameters at baseline, as in older patients and CAD patients, but inversely with early risk markers for subclinical atherosclerosis.

scholarly journals Effect of increased serum 25(OH)D and calcium on structure and function of post-menopausal women: a pilot study

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
H. J. Hillstrom ◽  
R. Soeters ◽  
M. Miranda ◽  
S. I. Backus ◽  
J. Hafer ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Muscle Fatigue ◽  
Repeated Measures ◽  
Vastus Lateralis ◽  
Structure And Function ◽  
Muscle Size ◽  
Menopausal Women ◽  
Post Menopausal ◽  
And Function

Abstract Summary The purpose was to determine if increasing serum 25(OH)D and calcium in postmenopausal women increased skeletal muscle size, strength, balance, and functional task performance while decreasing muscle fatigue. PCSA of the vastus lateralis increased and ascent of stairs time decreased after 6 months of increased serum 25(OH)D. Purpose The Institute of Medicine recommends ≥ 20 ng/ml of serum 25-hydroxyvitamin D [25(OH)D] for bone and overall health. Serum 25(OH)D levels have been associated with physical performance, postural sway, and falls. The purpose of this study was to determine if increasing postmenopausal women’s serum 25(OH)D levels from 20–30 ng/ml to 40–50 ng/ml improved skeletal muscle size, strength, balance, and functional performance while decreasing skeletal muscle fatigue. Methods Twenty-six post-menopausal women (60–85 years old) with baseline serum 25(OH)D levels between 20 and 30 ng/ml were recruited. Oral over-the-counter (OTC) vitamin D3 and calcium citrate were prescribed to increase subjects’ serum 25(OH)D to levels between 40 and 50 ng/ml, serum calcium levels above 9.2 mg/dl, and PTH levels below 60 pg/ml, which were confirmed at 6 and 12 weeks. Outcome measures assessed at baseline and 6 months included muscle physiological cross-sectional area (PCSA), muscle strength, postural balance, time to perform functional tasks, and muscle fatigue. Repeated measures comparisons between baseline and follow-up were performed. Results Nineteen subjects completed the study. One individual could not afford the time commitment for the repeated measures. Three individuals did not take their vitamin D as recommended. Two subjects were lost to follow-up (lack of interest), and one did not achieve targeted serum 25(OH)D. Vastus lateralis PCSA increased (p = 0.007) and ascent of stair time decreased (p = 0.042) after 6 months of increasing serum 25(OH)D levels from 20–30 ng/ml to 40–50 ng/ml. Isometric strength was unchanged. Anterior-posterior center of pressure (COP) excursion and COP path length decreased (p < 0.1) albeit non-significantly, suggesting balance may improve from increased serum 25(OH)D and calcium citrate levels. Conclusions Several measures of muscle structure and function were sensitive to elevated serum 25(OH)D and calcium levels indicating that further investigation of this phenomenon in post-menopausal women is warranted.

scholarly journals Association between antenatal blood pressure and 5-year postpartum retinal arteriolar structural and functional changes

2019 ◽  
Vol 4 (1) ◽  
pp. e000355 ◽  
Author(s):  
Ralene Sim ◽  
Izzuddin Aris ◽  
Yap-Seng Chong ◽  
Tien Yin Wong ◽  
Ling-jun Li
Keyword(s):  
Blood Pressure ◽  
Mediation Analysis ◽  
Degrees Of Freedom ◽  
Underlying Mechanism ◽  
Structure And Function ◽  
Functional Changes ◽  
Microvascular Changes ◽  
And Function ◽  
Retinal Arteriolar

ObjectiveStudies have shown that hypertensive disorders of pregnancy (HDP) are associated with both postpartum retinal microvascular changes and cardiovascular (CV) risks. However, the underlying mechanism of HDP transitioning to microvascular and macrovascular changes remains unknown, due to the interaction between microvasculature and CV risks. In this study, we examined whether associations between antenatal systolic blood pressure (SBP) and postpartum retinal arteriolar changes are independent of postpartum CV risks.MethodsWe included 276 Singaporean mothers attending both baseline index pregnancy (2009–2010) and 5-year postpartum follow-up visits (2014–2015). We measured SBP at baseline. At follow-up, we assessed retinal microvascular structure and function with retinal photography and dynamic vessel analyser, together with CV risks using a validated 2008 Framingham Risk Score (FRS). We performed a traditional four-step mediation analysis using linear regression by adjusting for a series of baseline characteristics: age, ethnicity, college degree, prepregnancy body mass index and gestational diabetes mellitus diagnosis at baseline.ResultsWe found that each 10 mm Hg increase in baseline SBP was associated with reduced arteriolar calibre (−1.3 µm; 95% CI −3.0 to 0.2) and fractal dimension (−0.4 degrees of freedom (df); −1.0 to 0.2), and significantly with increased arteriolar constriction (0.5%; 0.001 to 1.0) at 5-year postpartum. Even though baseline SBP was associated with postpartum FRS, the latter was not associated with any retinal arteriolar measures. Therefore, no further mediation analysis was required.ConclusionOur study suggested that elevated SBP during pregnancy was associated with suboptimal retinal arteriolar structure and function independent of postpartum CV risks.

Vertebral Artery Sacrifice versus Skeletonization in the Setting of Cervical Spine Tumor Resection: Case Series

2020 ◽  
Vol 139 ◽  
pp. e601-e607 ◽  
Author(s):  
Erick M. Westbroek ◽  
Zach Pennington ◽  
Jeff Ehresman ◽  
A. Karim Ahmed ◽  
Philippe Gailloud ◽  
...  
Keyword(s):  
Cervical Spine ◽  
Vertebral Artery ◽  
Tumor Resection ◽  
Case Series ◽  
Spine Tumor ◽  
Cervical Spine Tumor

scholarly journals A Prospective Comparative Study on Cardiac Alterations After Surgery and Drug Treatment of Primary Aldosteronism

2021 ◽  
Vol 12 ◽  
Author(s):  
Yi-Lin Chen ◽  
Ting-Yan Xu ◽  
Jian-Zhong Xu ◽  
Li-Min Zhu ◽  
Yan Li ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Treatment Group ◽  
Drug Treatment ◽  
Primary Aldosteronism ◽  
Structure And Function ◽  
Cardiac Structure ◽  
Cardiac Structure And Function ◽  
And Function ◽  
Drug Treatment Group

BackgroundCurrent guideline recommends both surgery and drug treatment for primary aldosteronism. Treatment effects on the cardiac structure and function remain under investigation.ObjectiveWe performed a prospective study in patients with primary aldosteronism to compare effects of surgery and drug treatment on the cardiac structure and function as assessed by the left ventricular (LV) pressure-strain loop, a novel echocardiographic technique that incorporates myocardial deformation and LV pressure.MethodsOur study included 39 and 28 patients treated with surgery and a mineralocorticoid antagonist, respectively. We performed conventional and speckle tracking echocardiography at baseline and 3 and 6 months of follow-up.ResultsDuring follow-up, both surgery and drug treatment normalized serum potassium concentration and significantly reduced blood pressure. Both treatments significantly and similarly decreased LV mass index and left atrial volume index. However, only in the surgery group did global wasted work significantly decrease (200.8 ± 86.7 at baseline vs. 142.1 ± 58.1 mmHg% at 6 months) and global work efficiency (91.5 ± 3.1 vs. 93.6 ± 2.3%) and global longitudinal strain (−18.3 ± 2.7 vs. −19.2 ± 1.9%) significantly (p &lt; 0.01) increase at 6 months of follow-up. The corresponding differences from the changes in the drug treatment group were 39.5 mmHg% (95% CI, 17.1, 62.0 mmHg%), −1.64% (95% CI, −2.56, −0.71%), and −0.85% (95% CI, −1.51, −0.20%), respectively. In addition, the changes in global wasted work at 6 months of follow-up was significantly correlated with that in 24-h urinary aldosterone excretion in the drug treatment group (r = 0.54) and two groups combined (r = 0.55), but not the surgery group.ConclusionIn spite of similar serum potassium normalization and blood pressure control, surgical removal of an adrenal gland, but not mineralocorticoid receptor antagonism, showed early improvement in cardiac function.

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