scholarly journals Central Neurocytoma in the Fourth Ventricle: Case Report and Literature Review

2021 ◽  
Author(s):  
Jiangwei Ding ◽  
Yang Dong ◽  
Lei Wang ◽  
Baorui Guo ◽  
Xinxiao Li ◽  
...  
Keyword(s):  
Fourth Ventricle ◽  
Chinese Women ◽  
Clinical Manifestations ◽  
Central Neurocytoma ◽  
Subtotal Resection ◽  
Intracranial Tumour ◽  
Soap Bubble ◽  
Imaging Characteristics ◽  
Solid Lesions

Abstract Background: Central neurocytoma is a rare primary intracranial tumour that usually occurs in young people. Central neurocytoma is more common in the lateral ventricle, but it is rare in the fourth ventricle. Herein, we report a case of central neurocytoma in the fourth ventricle. To improve our understanding, diagnosis, and treatment of this disease, we reviewed the literature to analyse the age, gender, clinical manifestations, imaging characteristics, and surgical prognosis of CNC in the fourth ventricle.Case presentation: A 44-year-old Chinese women presented with headache and dizziness for 8 years, walking instability for 2 years, and aggravation for 1 month. MRI revealed a 3.0 cm × 3.6 cm ×3.4 cm lesion located in the fourth ventricle. The tumour was completely resected. Pathological results were consistent with central neurocytoma. The patient could not walk or speak fluently during post-operative period, and no recurrence was found during the seventh month of follow-up.Conclusions: Central neurocytoma in the fourth ventricle is a rare intracranial tumour that is difficult to diagnose preoperatively. However, it can be considered when cystic and solid lesions are present in the fourth ventricle, especially when the morphology is like a soap bubble. Surgery is the main treatment for CNC. Adjuvant radiotherapy can be considered for partial or subtotal resection cases, and the prognosis is good. No recurrence of central neurocytoma in the fourth ventricle has been reported thus far.

Preliminary Exploration of the Diagnosis and Treatment of Skull-Based Chondromyxoid Fibromas

2017 ◽  
Vol 15 (3) ◽  
pp. 270-277
Author(s):  
Kangmin He ◽  
Shize Jiang ◽  
Xin Zhang ◽  
Ying Mao ◽  
Wei Zhu ◽  
...  
Keyword(s):  
Clinical Manifestations ◽  
Treatment Strategies ◽  
Diagnosis And Treatment ◽  
Benign Tumors ◽  
Symptom Duration ◽  
Study Cohort ◽  
Imaging Characteristics ◽  
Subtotal Removal ◽  
Base Of The Skull

Abstract BACKGROUND Chondromyxoid fibromas (CMFs) are benign tumors that occur rarely in the skull base. OBJECTIVE To conduct a preliminary exploration of the diagnosis and treatment of cranial CMFs. METHODS A retrospective analysis of 19 cases of CMFs in the base of the skull between 2009 and 2014 in our hospital was conducted. The clinical manifestations, imaging characteristics, pathology, treatment strategies, and outcomes were examined. RESULTS The study cohort included 7 women (36.8%) and 12 men (63.2%), and symptom duration ranged from 1 mo to 5 yr. Of the 19 intracranial CMF cases examined, 15 (78.9%) conformed with the diagnostic criteria for extracranial CMF. Resection operations yielded subtotal removal of 13 tumors (68.4%) and partial removal of 6 tumors (31.6%). Postoperative pathological analysis demonstrated that the tumors were characterized by spindle-shaped or stellate cells arranged in a myxoid matrix without mitoses or permeation. Follow-up (range 2-7.3 yr; mean, 4.4 ± 1.7 yr) revealed that symptoms improved postoperatively in 15 cases (78.9%), were maintained in 2 cases (10.5%), and worsened in 2 cases (10.5%). Imaging follow-up revealed that residual tumors were stable in 18 cases (94.7%) and enlarged in 1 case (5.3%). CONCLUSION An accurate diagnosis should involve comprehensive consideration of clinical, radiological, and pathological features. The treatment strategy for CMFs consists of maximizing tumor removal while protecting adjacent key structures. Postoperative stereotactic radiotherapy is appropriate for residual tumors.

Cerebral Hemangioblastoma Without Von Hippel-Lindau Syndrome: A Report of 6 Cases

2020 ◽  
pp. 106689692093399
Author(s):  
Limei Qu ◽  
Chuanqi Lv ◽  
Tiefeng Ji ◽  
Yinping Wang ◽  
Jinlu Yu
Keyword(s):  
Parietal Lobe ◽  
Clinical Manifestations ◽  
Pathological Examination ◽  
Cystic Tumor ◽  
Mixed Tumor ◽  
Wild Type ◽  
Von Hippel Lindau ◽  
Imaging Characteristics ◽  
Von Hippel Lindau Syndrome

Background. Hemangioblastoma occurs mainly in the cerebellum and rarely in the cerebrum. Objective. The present study aimed to analyze the clinical manifestations and radiological and pathological features of cerebral hemangioblastoma, and to improve the recognition of this tumor and avoid misdiagnosis. Methods. The characteristics of 6 patients with cerebral hemangioblastoma were analyzed, and a retrospective review of cerebral hemangioblastoma reported in the literature was performed. Results. All 6 patients were female, aged from 22 to 70 years (55 years on average), and all cases were wild-type sporadic, in which 4 cases occurred in the frontal lobe and 2 cases occurred in the parietal lobe. Imaging revealed a solid tumor in 4 cases, a cystic tumor in 1 case, and a mixed tumor in 1 case. Microscopically, the morphology and immunophenotype of tumor cells were not different from those of classical hemangioblastoma. All 6 patients survived tumor free during the follow-up period. Conclusions. Cerebral hemangioblastoma often simulates the imaging characteristics of meningioma or glioma. Enough attention should be paid to differential diagnosis before the operation, and exact diagnosis relies on the pathological examination.

scholarly journals Pancreatic Leiomyosarcoma With Schistosomiasis Hematobia: A Case Report and Literature Review

2021 ◽  
Vol 11 ◽  
Author(s):  
Qiang Li ◽  
Daniel Staiculescu ◽  
Yurong Zhou ◽  
Jiang Chen
Keyword(s):  
Case Report ◽  
Tumor Resection ◽  
Clinical Manifestations ◽  
Malignant Neoplasm ◽  
The Body ◽  
Imaging Characteristics ◽  
Magnetic Resonance Imaging Mri ◽  
The Relationship ◽  
Ct And Mri

Pancreatic leiomyosarcoma (PL) is a very rare, malignant neoplasm with a very poor prognosis. Here, we examine a novel case of PL with schistosomiasis hematobia. The patient had been initially misdiagnosed by the first magnetic resonance imaging (MRI). The second imaging examination demonstrated an enlarged heterogeneous tumor mass in the body-tail of pancreas. Following image analysis, the patient underwent a pancreatectomy, splenectomy and lymph node dissections. Sixteen months after the tumor resection, follow-up computed tomography (CT) and MRI revealed tumor metastasis in the liver and lung. PL has non-specific clinical manifestations and imaging characteristics, making early diagnosis very challenging. When it is difficult to distinguish between benign and malignant pancreatic lesions, short-term imaging follow-up is preferred. In this case report, we discuss the relationship between PL and schistosomiasis hematobia.

scholarly journals Intrasellar cavernous hemangiomas: A case report with a comprehensive review of the literature

2021 ◽  
Vol 12 ◽  
pp. 58
Author(s):  
Sultan Al-Saiari ◽  
Khalid Al-Orabi ◽  
Ahmed Farag ◽  
Zaina Brinji ◽  
Azza Azzouz ◽  
...  
Keyword(s):  
Clinical Improvement ◽  
Clinical Manifestations ◽  
Subtotal Resection ◽  
Frozen Sections ◽  
Review Of The Literature ◽  
Resonance Imaging ◽  
Comprehensive Review ◽  
Imaging Characteristics ◽  
Cavernous Hemangiomas ◽  
Delayed Contrast Enhancement

Background: Extra-axial cerebral cavernous hemangiomas particularly those found in the sellar region, are extremely rare. Their clinical manifestations and imaging characteristics can mimic those of a pituitary adenoma thus making preoperative diagnosis difficult. Few cases are reported in the literature. We present a case, along with a comprehensive review of the literature regarding specific aspects of diagnosis and management of all similarly reported rare cases. Case Description: We present the clinical, radiological, and operative data of a rare case of a large intrasellar cavernous hemangioma in a 49-year-old female patient presented with headache and diminution of vision, which was diagnosed intraoperatively during an endonasal endoscopic transsphenoidal approach. Subtotal debulking was performed with immediate postoperative clinical improvement. The patient was then referred for radiotherapy and maintained her clinical improvement since then. Conclusion: Neurosurgeons should consider this rare pathology in the preoperative differential diagnosis of sellar tumors. Bright hyperintense T2 signal with or without signal voids associated with centripetal delayed contrast enhancement in magnetic resonance imaging images might raise the suspicion which can be further confirmed intraoperatively with frozen sections. Due the reported high vascularity and intraoperative profuse bleeding leading to high operative morbidities, piecemeal subtotal resection followed by radiosurgery may be considered today as the safest and most effective strategy.

scholarly journals Melanocytoma of Optic Disc: Clinical Manifestations, Imaging Characteristics and Follow Up

2015 ◽  
Vol 3 (4) ◽  
pp. 113-116
Author(s):  
Rajan Paul ◽  
Manoj Kulshrestha ◽  
S. Shanmugalingam ◽  
Dai Barr
Keyword(s):  
Optic Disc ◽  
Clinical Manifestations ◽  
Imaging Characteristics

scholarly journals Intramedullary Spinal Cord Ependymoma after Posterior Fossa Ependymoma Resection: A Case Report

2016 ◽  
Vol 13 (1) ◽  
pp. 48-50
Author(s):  
Benju R Pradhan ◽  
Bal K Thapa
Keyword(s):  
Spinal Cord ◽  
Radiation Therapy ◽  
Posterior Fossa ◽  
Fourth Ventricle ◽  
Residual Tumor ◽  
Subtotal Resection ◽  
Intramedullary Spinal Cord ◽  
Ct Head

We experienced a case in which multiple spinal cord dissemination was found 6 years after resection of the fourth ventricle ependymoma. A 17-year-old boy had undergone a subtotal resection of the fourth ventricle ependymoma and radiation therapy to the posterior fossa when he was 12 years old. Follow up CT head detected no residual tumor until he complained of back pain and pain in right thigh 6 years after surgery. MRI revealed multiple mass at D10-12 and L2-3. He underwent laminectomy and excision of tumor. This case reminds us to the necessity for long term radiological follow up including the spinal cord even in benign ependymoma, although it is still not clear for how long and how often we should do it.Nepal Journal of Neuroscience 13:48-50, 2016

scholarly journals A rare observation of rosette-forming glioneuronal tumour of the fourth ventricle: a clinical case and literature review

2021 ◽  
Vol 5 ◽  
pp. 95-101
Author(s):  
A.G. Gavrilov ◽  
◽  
D.A. Odamanov ◽  
S.V. Shugai ◽  
F.D. Abdurakhimov ◽  
...  
Keyword(s):  
Fourth Ventricle ◽  
Primary Tumour ◽  
Clinical Manifestations ◽  
Subtotal Resection ◽  
Low Degree ◽  
Tumour Location ◽  
The Central Nervous System ◽  
Degree Of Malignancy ◽  
Specific Symptoms ◽  
Magnet Resonance

Rosette-forming glioneuronal tumour (RGNT) is a rare primary tumour of the central nervous system with a low degree of malignancy. Using such databases as PubMed, Web of Science and Google Scholar as well as terms “rosette and forming and glioneuronal”, we found 153 RGNT cases dated 2002-2020. Low occurrence of the disease and absence of specific symptoms make it possible to perform a differential diagnosis judging from the clinical picture. Clinical manifestations of the disease are rather variable and depend on the tumour location. Magnet-resonance tomography is the leading method for diagnosis of such disease. The article presents a case of successful treatment of a patient RGNT of the fourth ventricle. Subtotal resection of the tumour was performed due to its diffuse growth. Tumour residue is subject to dynamic follow-up observation

scholarly journals Clinical Characteristics of 20 Patients with Chronic Eosinophilic Pneumonia: A 6-year Retrospective Study

2020 ◽  
Author(s):  
Yang Xu ◽  
Zhanbo Wang ◽  
Zhaorui Zhang ◽  
Yu Dai ◽  
Qiang Zhu ◽  
...  
Keyword(s):  
Peripheral Blood ◽  
Clinical Manifestations ◽  
Lavage Fluid ◽  
Eosinophilic Pneumonia ◽  
Imaging Features ◽  
Course Of Disease ◽  
Chronic Eosinophilic Pneumonia ◽  
Imaging Characteristics ◽  
Blood Eosinophils

Abstract Background: Chronic eosinophilic pneumonia (CEP) is a rare disease and there are few systematic studies on the disease. We summarized the clinical and pathological data of CEP to improve the understanding of the disease, as well as to reduce misdiagnosis and mistreatment. Methods: The data of patients pathologically diagnosed as CEP in PLA General Hospital between May 2013 and May 2019 were collected, and the clinical manifestations, imaging characteristics, pathological features, treatment and prognosis were retrospectively analyzed. Results: There were 20 patients with CEP, including 6 males and 14 females. The average age at the time of diagnosis was 47.0 ± 10.2 (22-83) years, and the average course of disease was 15.5 ±11.5 (2-72) months. The main clinical manifestations were cough, dyspnea, expectoration, and shortness of breath, and often accompanied by fever, weight loss, and asthenia. 19 patients had elevated peripheral blood eosinophils, with the proportion of eosinophils ranging from 5.3-64.7%, and the absolute value of eosinophils ranging from 0.72-14.43×109/L. 18 patients had increased proportion of eosinophils in bronchoalveolar lavage fluid (BALF), ranging from 12-67%, with an average of 46%. The main imaging features were patchy shadows, consolidated shadows, and ground glass shadows. The histological examination of bronchial mucosal biopsy indicated eosinophilic infiltration in submucosal tissues and the pulmonary biopsy indicated a large number of eosinophils infiltration in alveolar cavity and septum as the main pathological changes of CEP. All of 20 patients were treated with glucocorticoid, and one of them relapsed during follow-up. Conclusions: The onset of CEP is insidious and the clinical manifestations are lack of specificity. Eosinophils increase in peripheral blood and BALF in most of CEP patients. The typical image is peripheral and subpleural distribution of lung infiltrates. The diagnosis of CEP depends on pathology, and glucocorticoid therapy is effective.

scholarly journals Intracranial Infection Caused by Multidrug-resistant Acinetobacter Baumannii

2021 ◽  
Vol 18 (4) ◽  
pp. 59-63
Author(s):  
Haiyong He ◽  
Manting Li ◽  
Ying Guo ◽  
Lun Luo ◽  
Robin Bhattarai ◽  
...  
Keyword(s):  
Acinetobacter Baumannii ◽  
Fourth Ventricle ◽  
Relevant Literature ◽  
Clinical Manifestations ◽  
Multidrug Resistant ◽  
External Ventricular Drainage ◽  
Ventricular Drainage ◽  
Intracranial Infection ◽  
Intracranial Infections

Objective: To report the successful treatment of a patient who underwent vestibular schwannoma resection and developed intracranial infection caused by multidrug-resistant Acinetobacter baumannii (MRAB), and to review the recent relevant literature. Methods: The patient was diagnosed with MRAB infection based on clinical manifestations and cerebrospinal fluid (CSF) culture. The treatment included external ventricular drainage, posterior fossa decompressive craniectomy, and endoscopic lavage for fourth ventricle, subdural drainage, and intravenous injection /ventricular irrigation of sulperazone. Results: The MRAB-induced intracranial infection was successfully cured. The follow-up lasted for 84 months, and the patient has resumed normal life and work. Conclusion: Active individualized treatment should be administered at the earliest. The drainage of CSF, ventricular lavage, and proper choice of antibiotics are key to treat intracranial infections caused by MRAB.

scholarly journals Clinical presentation and surgical outcomes of intramedullary neurenteric cysts

2015 ◽  
Vol 23 (1) ◽  
pp. 99-110 ◽  
Author(s):  
Tao Yang ◽  
Liang Wu ◽  
Jingyi Fang ◽  
Chenlong Yang ◽  
Xiaofeng Deng ◽  
...  
Keyword(s):  
Case Reports ◽  
Clinical Manifestations ◽  
Gross Total Resection ◽  
Neurological Deficits ◽  
Motor Deficit ◽  
Cervical Cord ◽  
Subtotal Resection ◽  
Total Resection ◽  
Cyst Recurrence

OBJECT Intramedullary neurenteric cysts (NECs) are exceedingly rare lesions and have been previously reported in case reports. The aim of this study was to determine the clinical manifestations, radiological features, and long-term prognosis of patients with such lesions. METHODS The authors retrospectively reviewed the records of 13 patients with an intramedullary NEC. Each patient underwent MRI, laminotomy, and microsurgery. The accurate diagnosis was based on imaging and pathology findings. Each patient's follow-up status was determined through individual office visits and a structured telephone interview. RESULTS The series included 7 male and 6 female patients. Progressive or intermittent motor deficit was the main symptom associated with or without pain or sensory disturbance. Five cysts were located in the cervical cord, 1 in the cervicothoracic cord, 3 in the thoracic cord, and 4 in the conus medullaris. Concurrent malformations included scoliosis (3 cases), fusion of rib (1 case), enlarged spinal canal (1 case), tethered spinal cord (1 case), and ectocardia (1 case). Gross-total resection of the cyst was achieved in 8 cases, and subtotal resection (STR) was achieved in 5 cases. All patients were followed up, with a mean duration of 66.5 months. Cyst recurrence was observed in 4 cases after STR. In 2 cases the patients underwent reoperation; the other 2 patients remained clinically stable and did not undergo reoperation. At the last evaluation, neurological function was improved in 11 patients and remained stable in 2 patients. CONCLUSIONS Intramedullary NECs should be considered in the differential diagnosis of a middle-aged patient with intermittent neurological symptoms and concurrent malformations. Early surgery is advocated to prevent permanent neurological deficits. When gross-total resection cannot be achieved, maximally safe removal under the protection of intraoperative neuromonitoring is advised. Because of the high risk of cyst recurrence, routine follow-up MRI is needed. If a residual cyst shows obvious regrowth and results in neurological deficits, timely reoperation with a goal of STR should be performed.

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