Understanding of Optimum Antibiotic Prophylaxis is Inconsistent Among Orthopaedic Surgery and Anesthesia Teams
Abstract Background Antibiotic surgical prophylaxis is a core strategy for the prevention of surgical site infections (SSI). Despite best practice guidelines and known efficacy of antibiotic prophylaxis in decreasing SSI risk, there is often wide variation in its use. We performed this study to assess antibiotic prophylaxis perspectives of orthopaedic surgery and anesthesiology teams at our institution regarding preoperative antibiotic choice, dosing, and timing.Methods An IRB approved questionnaire was distributed amongst orthopaedic surgery and anesthesia team members involved in preoperative antibiotic decision making from August 2017 to June 2019. The questionnaire addressed ten key practices relating to preoperative antibiotic use, including antibiotic choice, timing, rate of infusion, and dosing. Provider and service type responses were also compared using Chi-square tests. Results Two nurse practitioner (NP), 22 resident, and 23 attending orthopaedic surgery providers completed the survey. Twelve nurse anesthetist (CRNA), 6 resident, and 8 attending anesthesiology providers completed the survey. Only 30% of all providers agreed that both vancomycin and cefazolin are equally effective for the purpose of antibiotic prophylaxis. As for the antibiotic choice in patients with penicillin allergies, 50% agreed with vancomycin, 28% agreed with clindamycin, and 22% disagreed with both alternatives. Furthermore, resident physicians more frequently agreed with vancomycin (71%) compared to NPs (29%), and attendings physicians (35%) (p=0.014). A majority of providers agreed with the necessity of weight-based dosing and timely infusion of vancomycin.Conclusions There is no clear consensus amongst providers for which antibiotic to administer for antibiotic prophylaxis despite existing guidelines. Discrepancy exists between orthopaedic and anesthesia providers for which antibiotic to administer in patients with penicillin allergies. Institutions should evaluate antibiotic prophylaxis perspectives amongst their perioperative staff in order to identify any inconsistencies that could result in inappropriate antibiotic prophylaxis for patients. A multifactorial quality improvement strategy that includes development of a protocol, displaying prophylaxis guidelines in perioperative areas, educational training, a preoperative checklist, and optimizing the electronic medical record should be implemented to standardize prophylaxis practices. It is also integral to involve both the orthopaedic and the anesthesia staff in the quality improvement process otherwise discrepancies may continue to persist.