scholarly journals Disability-Adjusted Life Years (DALYs) and Mortality Rate Attributed to Unsafe Sex and Drug Use for AIDS in the Middle East and North Africa Countries

2020 ◽  
Author(s):  
Farid Najafi ◽  
Fatemeh Khosravi ◽  
Mojtaba Ghalandari ◽  
Mitra Darbandi
Keyword(s):  
Risk Factors ◽  
Mortality Rate ◽  
Drug Use ◽  
North Africa ◽  
Unsafe Sex ◽  
Disability Adjusted Life Years ◽  
Mena Countries ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Standardized Mortality Rate

Abstract Background: To reduce the burden of HIV/AIDS, it is important to identify and estimate the attributable burden of risk factors associated with HIV/AIDS. The present study aimed to estimate the attributable burden of unsafe sex and drug use in AIDS in the Middle East and North Africa (MENA) countries. Methods: We used the data in Global Burden of Disease (GBD) 2017 to estimate the attributable burden of unsafe sex and drug use in AIDS in the MENA (22 countries) from 1990 to 2017 by sex and age. We estimated the attributable mortality and disability-adjusted life-years (DALYs) for the mentioned risk factors.Results: The rate of DALYs/100,000 attributed to drug use for AIDS increased 1.10 (95% CI: 0.75-1.71) to 13.39 (95% CI: 9.98- 18.17) in women of MENA countries from 1990 to 2017, and there is an increasing trend in DALY attributable to drug use for AIDS in men. The rate of DALYs/100,000 attributed to unsafe sex for AIDS increased in women of MENA countries, 5.15 (95% CI: 3.34-8.07) to 53.44 (95% CI: 38.79-75.89); and 10.06 (95% CI: 6.61-16.18) to 46.16 (95% CI: 31.30-72.66) in men. Age-standardized mortality rate attributed to drug use and unsafe sex for AIDS increased from 1990 to 2017 in both sex in MENA.Conclusion: The rate of DALYs/100,000 and age-standardized mortality rate attributed to unsafe sex and drug use increased in MENA from 1990 to 2017. While most of such countries have traditional cultures with religious believes, such increase need to be addressed in more depth by all policy makers.

scholarly journals Correction to: Disability-adjusted life years and mortality rate attributed to unsafe sex and drug use for AIDS in the Middle East and North Africa countries

2021 ◽  
Vol 79 (1) ◽  
Author(s):  
Farid Najafi ◽  
Fatemeh Khosravi Shadmani ◽  
Mojtaba Ghalandari ◽  
Mitra Darbandi
Keyword(s):  
Middle East ◽  
Mortality Rate ◽  
Drug Use ◽  
North Africa ◽  
Unsafe Sex ◽  
Disability Adjusted Life Years ◽  
Disability Adjusted Life ◽  
Life Years

An amendment to this paper has been published and can be accessed via the original article.

Examination of incidence, mortality and disability-adjusted life years and risk factors of breast cancer in 49 Asian countries, 1990–2019: estimates from Global Burden of Disease Study 2019

2021 ◽  
Author(s):  
Rajesh Sharma
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Mortality Rate ◽  
Burden Of Disease ◽  
Global Burden ◽  
Disability Adjusted Life Years ◽  
Asian Countries ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Standardized Mortality Rate

Abstract Background This study presents an up-to-date, comprehensive and comparative examination of breast cancer’s temporal patterns in females in Asia in last three decades. Methods The estimates of incidence, mortality, disability-adjusted-life-years and risk factors of breast cancer in females in 49 Asian countries were retrieved from Global Burden of Disease 2019 study. Results In Asia, female breast cancer incidence grew from 245 045[226 259–265 260] in 1990 to 914 878[815 789–1025 502] in 2019 with age-standardized incidence rate rising from 21.2/100 000[19.6–22.9] to 35.9/100 000[32.0–40.2] between 1990 and 2019. The death counts more than doubled from 136 665[126 094–148 380] to 337 822[301 454–375 251]. The age-standardized mortality rate rose marginally between 1990 and 2019 (1990: 12.1[11.0–13.1]; 2019: 13.4[12.0–14.9]). In 2019, age-standardized incidence rate varied from 17.2/100 000[13.95–21.4] in Mongolia to 122.5[92.1–160.7] in Lebanon and the age-standardized mortality rate varied 4-fold from 8.0/100 000 [7.2–8.8] in South Korea to 51.9[39.0–69.8] in Pakistan. High body mass index (5.6%), high fasting plasma glucose (5.6%) and secondhand smoke (3.5%) were the main contributory risk factors to all-age disability-adjusted-life-years due to breast cancer in Asia. Conclusion With growing incidence, escalating dietary and behavioural risk factors and lower survival rates due to late-disease presentation in low- and medium-income countries of Asia, breast cancer has become a significant public health threat. Its rising burden calls for increasing breast cancer awareness, preventive measures, early-stage detection and cost-effective therapeutics in Asia.

scholarly journals Disability-adjusted life years and mortality rate attributed to unsafe sex and drug use for AIDS in the Middle East and North Africa countries

2020 ◽  
Vol 78 (1) ◽  
Author(s):  
Farid Najafi ◽  
Fatemeh Khosravi ◽  
Mojtaba Ghalandari ◽  
Mitra Darbandi
Keyword(s):  
Middle East ◽  
Drug Use ◽  
North Africa ◽  
Acquired Immunodeficiency Syndrome ◽  
Unsafe Sex ◽  
Disability Adjusted Life Years ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome

Abstract Background The Middle East and North Africa, is one of few regions where the number of new human immunodeficiency virus infections is increasing. The present study aimed to estimate the attributable burden of unsafe sex and drug use in Acquired immunodeficiency syndrome in the Middle East and North Africa countries. Methods We used the Global Burden of Disease data 2017 to estimate the attributable mortality and disability-adjusted life-years to unsafe sex and drug use in Acquired immunodeficiency syndrome in the Middle East and North Africa countries (21 countries) from 1990 to 2017 by region, sex and age. The percent change was calculated at three time points by country and sex. Results The rate of Disability-adjusted life years/100,000 attributed to drug use for Acquired immunodeficiency syndrome increased 1.10 (95% CI: 0.75–1.71) to 13.39 (95% CI: 9.98–18.17) in women of Middle East and North Africa countries from 1990 to 2017, and there is an increasing trend in Disability-adjusted life years attributable to drug use for Acquired immunodeficiency syndrome in men. The rate of Disability-adjusted life years/100,000 attributed to unsafe sex for Acquired immunodeficiency syndrome increased in women of Middle East and North Africa countries, 5.15 (95% CI: 3.34–8.07) to 53.44 (95% CI: 38.79–75.89); and 10.06 (95% CI: 6.61–16.18) to 46.16 (95% CI: 31.30–72.66) in men. Age-standardized mortality rate attributed to drug use and unsafe sex for Acquired immunodeficiency syndrome increased from 1990 to 2017 in both sex in Middle East and North Africa countries. Conclusion The rate of Disability-adjusted life years /100,000 and age-standardized mortality rate attributed to unsafe sex and drug use increased in Middle East and North Africa from 1990 to 2017. While most of such countries have traditional cultures with religious believes, such increase need to be addressed in more depth by all policy makers.

scholarly journals Disability-adjusted life years and mortality rate attributed to unsafe sex and drug use for AIDS in the Middle East and North Africa countries

2020 ◽  
Author(s):  
Farid Najafi ◽  
Fatemeh Khosravi ◽  
Mojtaba Ghalandari ◽  
Mitra Darbandi
Keyword(s):  
Middle East ◽  
Drug Use ◽  
North Africa ◽  
Acquired Immunodeficiency Syndrome ◽  
Unsafe Sex ◽  
Disability Adjusted Life Years ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome

Abstract Background: The Middle East and North Africa, is one of few regions where the number of new human immunodeficiency virus infections is increasing. The present study aimed to estimate the attributable burden of unsafe sex and drug use in Acquired immunodeficiency syndrome in the Middle East and North Africa countries. Methods: We used the Global Burden of Disease data 2017 to estimate the attributable mortality and disability-adjusted life-years to unsafe sex and drug use in Acquired immunodeficiency syndrome in the Middle East and North Africa countries (21 countries) from 1990 to 2017 by region, sex and age. The percent change was calculated at three time points by country and sex.Results: The rate of Disability-adjusted life years/100,000 attributed to drug use for Acquired immunodeficiency syndrome increased 1.10 (95% CI: 0.75-1.71) to 13.39 (95% CI: 9.98- 18.17) in women of Middle East and North Africa countries from 1990 to 2017, and there is an increasing trend in Disability-adjusted life years attributable to drug use for Acquired immunodeficiency syndrome in men. The rate of Disability-adjusted life years/100,000 attributed to unsafe sex for Acquired immunodeficiency syndrome increased in women of Middle East and North Africa countries, 5.15 (95% CI: 3.34-8.07) to 53.44 (95% CI: 38.79-75.89); and 10.06 (95% CI: 6.61-16.18) to 46.16 (95% CI: 31.30-72.66) in men. Age-standardized mortality rate attributed to drug use and unsafe sex for Acquired immunodeficiency syndrome increased from 1990 to 2017 in both sex in Middle East and North Africa countries.Conclusion: The rate of Disability-adjusted life years /100,000 and age-standardized mortality rate attributed to unsafe sex and drug use increased in Middle East and North Africa from 1990 to 2017. While most of such countries have traditional cultures with religious believes, such increase need to be addressed in more depth by all policy makers.

Disability-Adjusted Life Years and Mortality Rate Attributed to Brain and Central Nervous System Cancer in the Middle East and North Africa Countries

2021 ◽  
pp. 1-13
Author(s):  
Hamid Reza Saeidi Borojeni ◽  
Farid Najafi ◽  
Fatemeh Khosravi Shadmani ◽  
Zahra Darabi ◽  
Mitra Darbandi ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Mortality Rate ◽  
North Africa ◽  
Disability Adjusted Life Years ◽  
Mena Region ◽  
Central Nervous System Cancer ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Nervous System Cancer

<b><i>Background:</i></b> Primary brain tumors are among the main causes of death. This study aimed to determine the epidemiological features of the brain and central nervous system cancer in the Middle East and North Africa (MENA) region. <b><i>Methods:</i></b> In this study, data of the Global Burden of Disease (GBD) study were used to estimate the incidence, prevalence, deaths, disability-adjusted life years (DALYs), and mortality in 21 countries in the MENA region from 1990 to 2019 based on age and sex. The percentage of the changes of epidemiologic indicators was calculated between 1990 and 2019. <b><i>Results:</i></b> Palestine and Turkey had the highest rate of brain and central nervous system cancer in 2019. Saudi Arabia, Oman, Iraq, and Lebanon had the highest percentage of incidence rate changes from 1990 to 2019. The prevalence of brain and central nervous system cancer in the MENA region was increased from 7.51 (95% CI: 4.95–11.01) in 1990 to 16.45 (95% CI: 10.83–19.54) in 2019 (percentage of changes = 54.35%). The standardized age mortality rate in the MENA region was increased by 2.7% in 2019 compared to that in 1990. The rate of standardized age of DALY per 100,000 individuals in the MENA region decreased from 135.09 (95% CI: 92.57–199.92) in 1990 to 128.34 (95% CI: 87.81–151.3) in 2019. <b><i>Conclusion:</i></b> The incidence rate, prevalence, and standardized age mortality (per 100,000) had increased significantly in the MENA region in 2019 compared to those in 1990. Focusing on the diversity of the estimates of such indices in different countries of MENA can lead to the identification of important risk factors for brain cancer in future studies.

scholarly journals Systematic Analysis of the Global, Regional and National Burden of Cardiovascular Diseases from 1990 to 2017

2021 ◽  
Author(s):  
Zhenkun Wang ◽  
Aihua Du ◽  
Hong Liu ◽  
Ziwei Wang ◽  
Jifa Hu
Keyword(s):  
Risk Factors ◽  
Cardiovascular Diseases ◽  
Mortality Rate ◽  
Systematic Analysis ◽  
Disability Adjusted Life ◽  
Life Years ◽  
National Burden ◽  
Comparative Risk ◽  
Disease Study ◽  
Standardized Mortality Rate

Abstract Background Previous studies on the burden of cardiovascular diseases (CVDs) were mainly based on limited data of the study period or area, or did not include detailed risk factor analysis. Objective To investigate up-to-date temporal and regional trends and risk factors of mortality and disability-adjusted life years (DALYs) attributed to CVDs by age, sex, and disease throughout the world. Methods Data for the disease burden of CVDs in 195 countries and territories from 1990 to 2017, including mortality, DALYs, age-standardized mortality rates, and age-standardized DALY rates, were estimated from the Global Burden of Disease Study 2017. Risk factors attributable to deaths and DALYs for CVDs were also estimated using the comparative risk assessment framework. Results The number of deaths from CVDs increased by 48.62%, from 11.94 (95% UI 11.78–12.18) million in 1990 to 17.79 (17.53–18.04) million in 2017. However, the age-standardized mortality rate decreased by an average of − 1.45% (− 1.72% to − 1.18%) annually. After fluctuation in the expected age-standardized mortality rate of CVDs in most of the socio-demographic index (SDI) scale, these rates decrease rapidly for SDI values of 0.7 and higher. In 2017, metabolic risks accounted for 73.48% of deaths and 73.25% of DALYs due to CVDs, behavioral factors accounted for 63.23% of deaths and 66.71% of attributable DALYs. Conclusion CVDs remain a major global health burden due to the increment in death numbers and DALYs. Aging and the main risk factors are the main drivers of mortality and health loss. More attention to main risk factors should be paid with supportive health policies.

scholarly journals Burden of Stroke in Myanmar

2021 ◽  
pp. 49-51
Author(s):  
Narayanaswamy Venketasubramanian ◽  
Yee Mon Khine ◽  
Ohnmar Ohnmar ◽  
Myat Po Po Kyaw Khin ◽  
Min Thit Win
Keyword(s):  
Rural Areas ◽  
Mechanical Thrombectomy ◽  
Disability Adjusted Life Years ◽  
Stroke Units ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Lower Blood ◽  
Life Years Lost ◽  
Standardized Mortality Rate ◽  
Age And Sex

Myanmar is home to over 51 million people. The age- and sex-standardized mortality rate due to stroke is 165.4/100,000, while the rate of age- and sex-standardized disability-adjusted life years lost due to stroke is 2971.3/100,000. The prevalence of stroke among adults aged 40–99 years is 1.5%. Stroke is the leading cause of morbidity and mortality and comprises 20% of the neurological workload. There are only 10 stroke units in the whole country. Doctors are aware of the importance of hypertension in stroke prevention and the need for physiotherapy after stroke, but, until recently and in rural areas, they also tend to use steroids and neuroprotectants, and lower blood pressure aggressively acutely after stroke; antiplatelets are not widely used. Thrombolysis service is available at some tertiary centers but mechanical thrombectomy is not yet available.

scholarly journals Risk of acute respiratory infection from crop burning in India: estimating disease burden and economic welfare from satellite and national health survey data for 250 000 persons

2019 ◽  
Vol 48 (4) ◽  
pp. 1113-1124 ◽  
Author(s):  
Suman Chakrabarti ◽  
Mohammed Tajuddin Khan ◽  
Avinash Kishore ◽  
Devesh Roy ◽  
Samuel P Scott
Keyword(s):  
Risk Factors ◽  
Respiratory Infection ◽  
Health Survey ◽  
Acute Respiratory Infection ◽  
Disease Burden ◽  
Crop Residue ◽  
Agricultural Crop ◽  
Disability Adjusted Life Years ◽  
Disability Adjusted Life ◽  
Life Years

Abstract Background Respiratory infections are among the leading causes of death and disability globally. Respirable aerosol particles released by agricultural crop-residue burning (ACRB), practised by farmers in all global regions, are potentially harmful to human health. Our objective was to estimate the health and economic costs of ACRB in northern India. Methods The primary outcome was acute respiratory infection (ARI) from India’s fourth District Level Health Survey (DLHS-4). DLHS-4 data were merged with Moderate-Resolution Imaging Spectroradiometer satellite data on fire occurrence. Mutually adjusted generalized linear models were used to generate risk ratios for risk factors of ARI. Overall disease burden due to ACRB was estimated in terms of disability-adjusted life years. Results Seeking medical treatment for ARI in the previous 2 weeks was reported by 5050 (2%) of 252 539 persons. Living in a district with intense ACRB—the top quintile of fires per day—was associated with a 3-fold higher risk of ARI (mutually adjusted risk ratio 2.99, 95% confidence interval 2.77 to 3.23) after adjustment for socio-demographic and household factors. Children under 5 years of age were particularly susceptible (3.65, 3.06 to 4.34 in this subgroup). Additional ARI risk factors included motor-vehicle congestion (1.96, 1.72 to 2.23), open drainage (1.91, 1.73 to 2.11), cooking with biomass (1.73, 1.58 to 1.90) and living in urban areas (1.35, 1.26 to 1.44). Eliminating ACRB would avert 14.9 million disability-adjusted life years lost per year, valued at US$152.9 billion over 5 years. Conclusions Investments to stop crop burning and offer farmers alternative crop-residue disposal solutions are likely to improve population-level respiratory health and yield major economic returns.

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