scholarly journals Visceral Adiposity Index and Atherogenic Index of Plasma as Useful Predictor of Cardiovascular Diseases Risk: Evidence From A Cohort Study in Iran

2021 ◽  
Author(s):  
Behrooz Hamzeh ◽  
Yahya Pasdar ◽  
Narmin Mirzaei ◽  
Roya Safari Faramani ◽  
Farid Najafi ◽  
...  
Keyword(s):  
Cohort Study ◽  
Cardiovascular Diseases ◽  
Communicable Disease ◽  
Density Lipoprotein ◽  
Visceral Adiposity ◽  
Atherogenic Index ◽  
Visceral Adiposity Index ◽  
Cross Sectional ◽  
Atherogenic Index Of Plasma ◽  
Adiposity Index

Abstract Background Visceral Adiposity index (VAI) and atherogenic index of plasma (AIP) are relatively new indicators for predicting Non-Communicable disease (NCDs). The aim of this study was to assess the association AIP and VAI with risk of cardiovascular diseases (CVDs). Methods This was a cross-sectional analysis conducted on 7362 individuals aged 35 to 65 years participated in Ravansar Non-Communicable Diseases (RaNCD) cohort study. AIP was calculated based on the value of triglyceride and high density lipoprotein cholesterol (HDL-C). VAI was calculated using Body mass index (BMI), waist circumference (WC), triglyceride, and HDL-C. All participants were stratified into three groups based on AIP and VAI tertiles. Logistic regression models were used to assess the association of AIP and VAI with CVDs. Results The mean of AIP and VAI was significantly higher in CVDs patients than in non-CVDs (P < 0.001). After adjusting for age, sex, BMI and physical activity the risk of CVDs in the second and third tertile of AIP were 1.22 (95% CI: 1.02, 1.45) and 1.40 (95% CI: 1.19, 1.66) times higher comparing to the first tertile, respectively. Risk of CVDs in the second and third tertile of VAI were 1.28 (95% CI: 1.06, 1.53) and 1.52 (95% CI: 1.25, 1.83) times higher than the first tertile, respectively; while adjusting for age, sex, hypertension and dyslipidemia and smoking. Conclusion According to the findings, AIP and VAI were positively associated with CVDs. Therefore, AIP and VAI can be useful in identifying high-risk subgroups of CVDs in general population.

scholarly journals Visceral Adiposity index and atherogenic index of plasma as reliable indices to prediction of cardiovascular diseases in adults: A Cross-Sectional analysis from the Iranian RaNCD Cohort Data

2021 ◽  
Author(s):  
Behrooz Hamzeh ◽  
Yahya Pasdar ◽  
Narmin Mirzaei ◽  
Roya Safari Faramani ◽  
Farid Najafi ◽  
...  
Keyword(s):  
Cardiovascular Diseases ◽  
Serum Triglyceride ◽  
Visceral Adiposity ◽  
Atherogenic Index ◽  
Visceral Adiposity Index ◽  
Cross Sectional ◽  
Atherogenic Index Of Plasma ◽  
Adiposity Index ◽  
Cross Sectional Analysis ◽  
Sectional Analysis

Abstract Background: Visceral Adiposity index (VAI) and atherogenic index of plasma (AIP) are relatively new indicators for predicting Non-Communicable disease (NCDs). The aim of this study was to assess the association AIP and VAI with risk of developing cardiovascular diseases (CVDs) in adults.Materials: This was a cross-sectional analysis conducted on 7362 individuals aged 35 to65 years participated in Ravansar Non-Communicable Diseases (RaNCD) cohort study. AIP was calculated based on the value of TG and HDL-C. VAI was calculated using BMI (Body mass index), waist circumference (WC), serum triglyceride, and High density lipoprotein cholesterol (HDL-C).All participants were stratified into three groups based on AIP and VAI tertiles. Simple and multiple logistic regression models were applied to assess the effect of these indices on CVDs.Results: The mean of AIP and VAI was significantly higher in CVDs patients than in non-CVDs (P < 0.001). After adjusting for age, sex hypertension, hyperlipidemia and smoking the risk of CVDs in the second and third tertile of AIP were 1.27 (95% CI: 1.06, 1.52) and 1.63 (95% CI: 1.31, 2.03) times higher comparing to the first tertile, respectively. Risk of CVDs in the second and third tertile of VAI were1.41 (95% CI: 1.18, 1.70) and 1.98 (95% CI: 1.60, 2.46) times higher than the first tertile, respectively; while adjusting for age, sex, hypertension and dyslipidemia.Conclusion: According to the findings, AIP and VAI were positively associated with CVDs in adults. Therefore, AIP and VAI can be useful in identifying high-risk subgroups of CVDs in general population.

scholarly journals The Effect of Edible Lipids on Atherogenic Index of Plasma: Results From RaNCD Cohort Study

2020 ◽  
Author(s):  
Badrieh Sahargahi ◽  
Yahya Pasdar ◽  
Mehdi Moradinazar ◽  
Farid Najafi ◽  
Mitra Darbandi ◽  
...  
Keyword(s):  
Cohort Study ◽  
Vegetable Oil ◽  
Edible Oils ◽  
Communicable Disease ◽  
Atherogenic Index ◽  
Cvd Risk ◽  
Cross Sectional ◽  
Atherogenic Index Of Plasma ◽  
Hydrogenated Oil ◽  
Hydrogenated Vegetable Oil

Abstract Background: The amount and type of lipids consumed has a great impact on serum lipid profile and risk of cardiovascular diseases (CVDs). A novel index named atherogenic index of plasma (AIP) is better predictors of CVD risk factors than lipids alone. This study aimed to investigate the effect of edible oils on AIP. Methods: This cross-sectional study conducted on preliminary phase of Ravansar Non-Communicable Disease (RaNCD) cohort study. The amount of consumption of edible lipids was determined based on validated Food Frequency Questionnaire (FFQ). Lipid profiles including triglyceride (TG), and lipoprotein cholesterol (HDL-C) were measured, and AIP was calculated as log10 (TG/HDL-C).Results: A total of 9996 individuals, 4738(47.4%) were male. The mean of AIP was 0.98±0.6 (range from -1.73 to 4.15) that in females (0.97 ± 0.6) was lower than males (1.10 ± 0.6). After controlling for confounding and affecting variables, the AIP index decreased with increasing consumption of a local oil named Kermanshahi oil [β(CI 95% ): -0.006(-0.008, -0.003)], butter[β(CI 95% ): -0.008(-0.011, -0.005)] and not statistically significant decrease with Hydrogenated or partial hydrogenated oil [β(CI 95% ): -0.008(-0.001, 0.001)] but the AIP index increased with un-hydrogenated oil [β(CI 95% ): 0.001(-0.001, 0.001)]Conclusion: Kermanshahi oil and butter have decreasing effect on AIP, the effect of margarine was neutral, hydrogenated vegetable oil has trace decreasing effect whereas un-hydrogenated vegetable oil has increasing effect on it. So, consumption of Kermanshahi oil may be associated with lower cardiovascular risk.

scholarly journals Visceral adiposity index and atherogenic index of plasma as useful predictors of risk of cardiovascular diseases: evidence from a cohort study in Iran

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Behrooz Hamzeh ◽  
Yahya Pasdar ◽  
Narmin Mirzaei ◽  
Roya Safari Faramani ◽  
Farid Najafi ◽  
...  
Keyword(s):  
Cohort Study ◽  
Cardiovascular Diseases ◽  
Lipid Profile ◽  
Atherogenic Index ◽  
Visceral Adiposity Index ◽  
Anthropometric Indices ◽  
Atherogenic Index Of Plasma ◽  
Non Communicable Diseases ◽  
Mean Values ◽  
The Third

Abstract Background Visceral adiposity index (VAI) and atherogenic index of plasma (AIP) are relatively new indicators for predicting non-communicable diseases (NCDs). Therefore, the present study was done to assess the association of AIP and VAI with risk of cardiovascular diseases (CVDs). Methods This cross-sectional study was conducted on 7,362 individuals aged between 35 and 65 years old participated in Ravansar non-communicable diseases (RaNCD) cohort study. AIP was calculated based on levels of triglyceride and high -density lipoprotein cholesterol (HDL-C). VAI was calculated using values of body mass index (BMI), waist circumference (WC), triglyceride, and HDL-C. Logistic regression models were used to assess the association of AIP and VAI with risk of CVDs. Results Mean values of anthropometric indices, lipid profile, AIP, and VAI were significantly higher in patients with CVDs than individuals without CVDs (P < 0.001). Mean values of anthropometric indices, lipid profile, and NCDs including hypertension, dyslipidemia, diabetes, metabolic syndrome (MetS), and CVDs in the third tertile of AIP and VAI were significantly increased compared to the first tertile (P < 0.001). After adjusting confounding factors, risk of CVDs in the third tertile of AIP was (OR = 1.32, 95 % CI: 1.03, 1.69) significantly increased compared to the first tertile. Risk of CVDs in the third tertile of VAI was (OR = 1.48, 95 % CI: 1.12, 1.97) significantly increased compared to the first tertile. Conclusions According to the findings, AIP and VAI were positively associated with risk of CVDs. Therefore, AIP and VAI can be useful in identifying high-risk subgroups of CVDs in general population.

scholarly journals The Relationship Between the Atherogenic Index of Plasma and Arterial Stiffness in Essential Hypertensive Patients from China: A Cross-Sectional Study

2021 ◽  
Author(s):  
Juan Yin ◽  
Minghui Li ◽  
Lingling Yu ◽  
Feng Hu ◽  
Yu Yu ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Arterial Stiffness ◽  
Linear Regression Analysis ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Atherogenic Index ◽  
Multivariate Linear Regression Analysis ◽  
Sectional Study ◽  
Cross Sectional ◽  
Atherogenic Index Of Plasma

Abstract Background: The atherogenic index of plasma (AIP) always remains in a potential association with the arterial stiffness, however, in large hypertensive patient populations, this relation is not fully discovered and needs to be studied in depth. The present analysis thus sought to further explore the association that exists between AIP and arterial stiffness in patients diagnosed with arterial hypertension in China.Methods: This cross-sectional study analyzed 4744 Chinese individuals with essential hypertension. AIP was defined as the base 10 logarithm of the ratio of plasma of triglycerides (TG) to high-density lipoprotein cholesterol (HDL-c) levels indicates as in molar concentrations. Measurement of arterial stiffness was carried out via brachial-ankle pulse wave velocity (baPWV).Results: Data were adjusted for potential confounding variables, after which a multivariate linear regression analysis revealed AIP to be positively correlated with baPWV (β = 1.34, 95% CI: 0.96 to 1.72, P < 0.001). When AIP was instead treated as a categorical variable divided into quartiles, this same relationship was observed (P for trend < 0.001). We additionally found AIP and baPWV had a stronger positive association in individuals with a body mass index (BMI) < 24 kg/m2 (P for interaction < 0.05).Conclusion: AIP and arterial stiffness were positively correlated in essential hypertension patients in China, especially in those with a BMI < 24 kg/m2.

Chinese visceral adiposity index, a novel indicator of visceral obesity for assessing the risk of incident hypertension in a prospective cohort study

2020 ◽  
pp. 1-9
Author(s):  
Minghui Han ◽  
Ranran Qie ◽  
Quanman Li ◽  
Leilei Liu ◽  
Shengbing Huang ◽  
...  
Keyword(s):  
Cohort Study ◽  
Characteristic Curve ◽  
Visceral Obesity ◽  
Visceral Adiposity ◽  
Sensitivity Analyses ◽  
Cluster Sampling ◽  
Visceral Adiposity Index ◽  
Adiposity Index ◽  
Hypertension Risk ◽  
Obesity Indices

Abstract The present study aimed to investigate the association of the Chinese visceral adiposity index (CVAI) and its 6-year change with hypertension risk and compare the ability of CVAI and other obesity indices to predict hypertension based on the Rural Chinese Cohort Study. Study participants were randomly recruited by a cluster sampling procedure, and 10 304 participants ≥18 years were included. Modified Poisson regression was used to derive adjusted relative risks (RR) and 95 % CI. We identified 2072 hypertension cases during a median of 6·03 years of follow-up. The RR for the highest v. lowest CVAI quartile were 1·29 (95 % CI 1·05, 1·59) for men and 1·53 (95 % CI 1·22, 1·91) for women. Per-sd increase in CVAI was associated with hypertension for both men (RR 1·09, 95 % CI 1·02, 1·16) and women (RR 1·14, 95 % CI 1·06, 1·22). Also, the area under the receiver operating characteristic curve value for hypertension was higher for CVAI than the four other obesity indices for both sexes (all P < 0·05). Finally, per-sd increase in CVAI change was associated with hypertension for both men (RR 1·26, 95 % CI 1·16, 1·36) and women (RR 1·23, 95 % CI 1·15, 1·30). Similar results were observed in sensitivity analyses. CVAI and its 6-year change are positively associated with hypertension risk. CVAI has better performance in predicting hypertension than other visceral obesity indices for both sexes. The current findings suggest CVAI as a reliable and applicable predictor of hypertension in rural Chinese adults.

Sign in / Sign up

Export Citation Format

Share Document