scholarly journals Bacteria Patterns on Tonsillar Surface and Tonsillar Core Tissue among Patients Scheduled for Tonsillectomy at Bugando Medical Centre

2021 ◽  
Author(s):  
Gustave Buname ◽  
Gapto Kiwale ◽  
Vitus Silago ◽  
Martha F Mushi ◽  
Stephen E Mshana
Keyword(s):  
Bacterial Pathogen ◽  
Positive Culture ◽  
Medical Centre ◽  
Microbiology Laboratory ◽  
Bugando Medical ◽  
Positive Growth ◽  
Standard Operating ◽  
Core Tissue ◽  
Bugando Medical Centre ◽  
Culture Positive

Abstract Background: Tonsillitis is an inflammation of tonsils due to either viruses or bacteria. Here we report the bacteria patterns on tonsillar surface and tonsillar core tissue among patients scheduled for tonsillectomy at Bugando Medical Centre (BMC), Mwanza Tanzania.Methods: The study included 120 patients planned for tonsillectomy between April and July 2019. Swab samples from tonsilar surface pre-tonsillectomy and core post-tonsillectomy were collected. Culture was performed following the microbiology laboratory standard operating procedures. Data analysis was done using STATA version 13 as per study objectives.Results: The slightly majority of participants were males 73 (60.83%) with median age of 6 [IQR 4-11] years. The proportion of culture positive growth was high on surface than in core swab samples 65(54.2%) vs 42(35.0%), p=0.003. The commonest bacterial pathogen detected from the surface and core were S. aureus 29(40.3%) and 22(51.2%), followed by S. pyogenes, 17(23.6%) and 11(25.6%), respectively. Features suggestive of tonsillitis on histology were reported in 83 (73.5%) of samples. Conclusion: More than two-third of patients undergoing tonsillectomy had positive culture of possible bacterial pathogens. Streptococcus pyogenes and Staphylococcus aureus were the predominant bacteria detected. More studies to investigate the treatment outcome of these patients are highly recommended.

scholarly journals Bacteria Patterns on Tonsillar Surface and Tonsillar Core Tissue among Patients Scheduled for Tonsillectomy at Bugando Medical Centre, Mwanza, Tanzania

Pathogens ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 1560
Author(s):  
Gustave Buname ◽  
Gapto Aristides Kiwale ◽  
Martha F. Mushi ◽  
Vitus Silago ◽  
Peter Rambau ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Streptococcus Pyogenes ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Bacterial Pathogen ◽  
Positive Culture ◽  
Medical Centre ◽  
Bugando Medical ◽  
Core Tissue ◽  
Culture Growth ◽  
Bugando Medical Centre

Background: Tonsillitis is an inflammation of the tonsils due to either viruses or bacteria. Here, we report the bacteria patterns on the tonsillar surface and tonsillar core tissue among patients scheduled for tonsillectomy at Bugando Medical Centre (BMC), Mwanza Tanzania. Methods: The study included 120 patients planned for tonsillectomy between April and July 2019. Swab samples from tonsillar surface pre-tonsillectomy and core post-tonsillectomy were collected. Culture was performed following the microbiology laboratory standard operating procedures. Data analysis was completed using STATA version 13, as per the study objectives. Results: The slight majority of participants were males (73; 60.83%) with median age of 6 years (interquartile range 4–11). The proportion of positive culture growth was higher on the surface than in core swab samples: 65 (54.2%) vs. 42 (35.0%), p = 0.003. The commonest bacterial pathogen detected from the surface and core were S. aureus in 29 (40.3%) and 22 (51.2%) participants, followed by S. pyogenes in 17 (23.6%) and 11 (25.6%), respectively. Methicillin-resistant Staphylococcus aureus (MRSA) was observed in 20/51 (39%) of isolates. Streptococcus pyogenes resistance to macrolides ranged from 8.3% for core isolates to 35.3% for surface isolates. Features suggestive of tonsillitis on histology were reported in 83 (73.5%) samples. Conclusion: More than two-thirds of patients undergoing tonsillectomy had a positive culture for possible bacterial pathogens. Staphylococcus aureus and Streptococcus pyogenes were the predominant bacteria detected with more than one third of Staphylococcus aureus being MRSA. More studies to investigate the treatment outcome of these patients are highly recommended.

scholarly journals Incidence and predictors of surgical site infections following caesarean sections at Bugando Medical Centre, Mwanza, Tanzania

2014 ◽  
Vol 3 (1) ◽  
pp. 25 ◽  
Author(s):  
Filbert J Mpogoro ◽  
Stephen E Mshana ◽  
Mariam M Mirambo ◽  
Benson R Kidenya ◽  
Balthazar Gumodoka ◽  
...  
Keyword(s):  
Surgical Site Infections ◽  
Medical Centre ◽  
Bugando Medical ◽  
Bugando Medical Centre

scholarly journals AWARENESS OF CHEMOTHERAPY SIDE EFFECTS AND ATTITUDE TOWARDS CHEMOTHERAPY USE AMONG CANCER PATIENTS ATTENDING ONCOLOGY CLINIC AT BUGANDO MEDICAL CENTRE, IN MWANZA, NORTHERN TANZANIA

2018 ◽  
Vol 8 (5) ◽  
pp. 448-454 ◽  
Author(s):  
Deogratias M Katabalo ◽  
Raphael Matinde ◽  
Stanley Mwita ◽  
Karoli Marwa ◽  
Nestory Masalu
Keyword(s):  
Side Effects ◽  
Cancer Cells ◽  
Cancer Patients ◽  
Cross Section ◽  
Positive Attitude ◽  
Medical Centre ◽  
Bugando Medical ◽  
Northern Tanzania ◽  
Chemotherapy Side Effects ◽  
Bugando Medical Centre

Background: Chemotherapy is the use of drugs to kill cancer cells. Because cancer cells generally grow and divide faster than normal cells, they are more susceptible to the action of these drugs. However, damage to healthy cells is unavoidable, and this damage accounts for the side effects linked to these drugs. Methodology: A cross section study was conducted at oncology department in Bugando Medical Centre. A sample of 216 people was recruited into the study. The data was collected by using the pre-constructed questionnaire. After data collection, the data was transferred into SPSS version 20 and analyzed. Results: The study found that 88 (40.7%) of the respondents were aware of the chemotherapy side effects whereby majority, 68 (77.3%) of these had been informed by the doctor. Most of the respondents, 197 (92.1%) had a positive attitude towards the use of chemotherapy. Conclusion: There is still poor awareness of the chemotherapy side effects among the cancer patients attending and receiving chemotherapy in oncology department at Bugando Medical Centre. However, most of the respondents had positive attitude towards the use of chemotherapy Keywords: Awareness, attitude, chemotherapy, side effects and Tanzania.

scholarly journals Comparative Evaluation of Enteric Bacterial Culture and a Molecular Multiplex Syndromic Panel in Children with Acute Gastroenteritis

2019 ◽  
Vol 57 (6) ◽  
Author(s):  
Thomas Kellner ◽  
Brendon Parsons ◽  
Linda Chui ◽  
Byron M. Berenger ◽  
Jianling Xie ◽  
...  
Keyword(s):  
Pathogen Detection ◽  
Rectal Swab ◽  
Bacterial Pathogen ◽  
Positive Culture ◽  
Content Type ◽  
Negative Culture ◽  
Percent Agreement ◽  
Stool Samples ◽  
Culture Positive ◽  
Culture Negative

ABSTRACTAlthough enteric multianalyte syndromic panels are increasingly employed, direct comparisons with traditional methods and the inclusion of host phenotype correlations are limited. Luminex xTAG gastrointestinal pathogen panel (GPP) and culture results are highly concordant. However, phenotypic and microbiological confirmatory testing raises concerns regarding the accuracy of the GPP, especially forSalmonellaspp. A total of 3,089 children with gastroenteritis submitted stool specimens, rectal swab specimens, and clinical data. The primary outcome was bacterial pathogen detection agreement for shared targets between culture and the Luminex xTAG GPP. Secondary analyses included phenotype assessment, additional testing of GPP-negative/culture-positive isolate suspensions with the GPP, and in-house and commercial confirmatory nucleic acid testing of GPP-positive/culture-negative extracts. The overall percent agreement between technologies was >99% for each pathogen.Salmonellaspp. were detected in specimens from 64 participants: 12 (19%) by culture only, 9 (14%) by GPP only, and 43 (67%) by both techniques. Positive percent agreement forSalmonellaspp. was 78.2% (95% confidence interval [CI], 64.6%, 87.8%). Isolate suspensions from the 12 participants with specimens GPP negative/culture positive forSalmonellatested positive by GPP. Specimens GPP positive/culture negative forSalmonellaoriginated in younger children with less diarrhea and more vomiting. GPP-positive/culture-negative specimen extracts tested positive using additional assays for 0/2Campylobacter-positive specimens, 0/4Escherichia coliO157-positive specimens, 0/9Salmonella-positive specimens, and 2/3Shigella-positive specimens. For both rectal swab and stool samples, the median cycle threshold (CT) values, determined using quantitative PCR, were higher for GPP-negative/culture-positive samples than for GPP-positive/culture-positive samples (for rectal swabs, 36.9 [interquartile range {IQR}, 33.7, 37.1] versus 30.0 [IQR, 26.2, 33.2], respectively [P = 0.002]; for stool samples, 36.9 [IQR, 33.7, 37.1] versus 29.0 [IQR, 24.8, 30.8], respectively [P = 0.001]). GPP and culture have excellent overall agreement; however, for specific pathogens, GPP is less sensitive than culture and, notably, identifies samples false positive forSalmonellaspp.

Expanding Neurosurgical Care in Northwest Tanzania: The Early Experience of an Initiative to Teach Neurosurgery at Bugando Medical Centre

2012 ◽  
Vol 77 (1) ◽  
pp. 32-38 ◽  
Author(s):  
David A. Wilson ◽  
Mark P. Garrett ◽  
Scott D. Wait ◽  
Elisa J. Kucia ◽  
Emmanuel Saguda ◽  
...  
Keyword(s):  
Early Experience ◽  
Medical Centre ◽  
Bugando Medical ◽  
Bugando Medical Centre
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