scholarly journals Leukemia mortality in children from Latin America: Trends and predictions to 2030

2020 ◽  
Author(s):  
J. Smith Torres-Roman ◽  
Bryan Valcarcel ◽  
Pedro Guerra-Canchari ◽  
Camila Alves Dos Santos ◽  
Isabelle Ribeiro Barbosa ◽  
...  
Keyword(s):  
Latin American ◽  
Mortality Rates ◽  
World Health ◽  
Mortality Data ◽  
Mortality Trends ◽  
Annual Percent Change ◽  
Universal Healthcare ◽  
The World ◽  
Health Organization ◽  
Universal Healthcare Coverage

Abstract Background: Reports suggest that Latin American and Caribbean (LAC) countries have not reduced in leukemia mortality compared to high-income countries. However, updated trends remain largely unknown in the region. Given that leukemia is the leading cause of cancer-related death in LAC children, we evaluated mortality trends in children (0-14y) from 15 LAC countries for the period 2000-2017 and predicted mortality to 2030.Methods: We retrieved cancer mortality data using the World Health Organization Mortality Database. Mortality rates (standardized to the world standard SEGI population) were analyzed for 15 LAC countries. We evaluated the average mortality rates for the last 5 years (2013-2017). Joinpoint regression analysis was used to evaluate leukemia mortality trends and provide an estimated annual percent change (EAPC). Nordpred was utilized for the calculation of predictions until 2030.Results: Between 2013 and 2017, the highest mortality rates were reported in Venezuela, Ecuador, Nicaragua, Mexico, and Peru. Upward mortality trends were reported in Nicaragua (EAPC by 2.9% in boys, and EAPC by 2.0% in girls), and Peru (EAPC by 1.4% in both sexes). Puerto Rico experienced large declines in mortality among both boys (EAPC by −9.7%), and girls (EAPC by −6.0%). Leukemia mortality will increase in Argentina, Ecuador, Guatemala, Panama, Peru, and Uruguay by 2030.Conclusion: Leukemia mortality is predicted to increase in some LAC countries by 2030. Interventions to prevent this outcome should be tailor to reduce the socioeconomic inequalities and ensure universal healthcare coverage.

scholarly journals Leukemia mortality in children from Latin America: trends and predictions to 2030

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
J. Smith Torres-Roman ◽  
Bryan Valcarcel ◽  
Pedro Guerra-Canchari ◽  
Camila Alves Dos Santos ◽  
Isabelle Ribeiro Barbosa ◽  
...  
Keyword(s):  
Latin American ◽  
Mortality Rates ◽  
World Health ◽  
Mortality Data ◽  
Mortality Trends ◽  
Annual Percent Change ◽  
Universal Healthcare ◽  
The World ◽  
Health Organization ◽  
Universal Healthcare Coverage

Abstract Background Reports suggest that Latin American and Caribbean (LAC) countries have not reduced leukemia mortality compared to high-income countries. However, updated trends remain largely unknown in the region. Given that leukemia is the leading cause of cancer-related death in LAC children, we evaluated mortality trends in children (0-14y) from 15 LAC countries for the period 2000–2017 and predicted mortality to 2030. Methods We retrieved cancer mortality data using the World Health Organization Mortality Database. Mortality rates (standardized to the world standard SEGI population) were analyzed for 15 LAC countries. We evaluated the average mortality rates for the last 5 years (2013–2017). Joinpoint regression analysis was used to evaluate leukemia mortality trends and provide an estimated annual percent change (EAPC). Nordpred was utilized for the calculation of predictions until 2030. Results Between 2013 and 2017, the highest mortality rates were reported in Venezuela, Ecuador, Nicaragua, Mexico, and Peru. Upward mortality trends were reported in Nicaragua (EAPC by 2.9% in boys, and EAPC by 2.0% in girls), and Peru (EAPC by 1.4% in both sexes). Puerto Rico experienced large declines in mortality among both boys (EAPC by − 9.7%), and girls (EAPC by − 6.0%). Leukemia mortality will increase in Argentina, Ecuador, Guatemala, Panama, Peru, and Uruguay by 2030. Conclusion Leukemia mortality is predicted to increase in some LAC countries by 2030. Interventions to prevent this outcome should be tailor to reduce the socioeconomic inequalities and ensure universal healthcare coverage.

scholarly journals Leukemia mortality in children from Latin America: Trends and predictions to 2030

2020 ◽  
Author(s):  
J. Smith Torres-Roman ◽  
Bryan Valcarcel ◽  
Pedro Guerra-Canchari ◽  
Camila Alves Dos Santos ◽  
Isabelle Ribeiro Barbosa ◽  
...  
Keyword(s):  
Latin American ◽  
Mortality Rates ◽  
World Health ◽  
Mortality Data ◽  
Mortality Trends ◽  
Annual Percent Change ◽  
Control Programs ◽  
Standard Population ◽  
Health Organization ◽  
Treatment Abandonment

Abstract Background Reports suggest that Latin American and Caribbean (LAC) countries have not achieved the downward mortality trends in leukemia seen in other countries. However, updated trends remain largely unknown in the region. Given that leukemia is the leading cause of cancer-related death in LAC children, we aimed to evaluate mortality trends in children (0-14y) from 15 LAC countries for the period 2000–2017 and to predict mortality until 2030. Methods We retrieved cancer mortality data through the World Health Organization Mortality Database. Age-standardized (world standard population) rates were computed for LAC countries. Joinpoint regression analysis was used to examine trends in the mortality rates of leukemia and provide an estimated annual percent change (EAPC). Nordpred was utilized for the calculation of predictions until 2030. Results Between 2013 and 2017, the highest mortality rates were reported in Venezuela, Ecuador, Nicaragua, Mexico, and Peru. Upward mortality trends were reported in Nicaragua (EAPC by 1.2% in boys, and EAPC by 2.0% in girls), Panama (EAPC by 1.8% in boys, and by 2.7% in girls), and Peru (EAPC by 1.4% in both sexes). Puerto Rico experienced large declines in mortality among both boys (APC by − 9.7%), and girls (EAPC by − 6.0%). Forecasting models predicted that leukemia mortality between 2015 and 2030, will increase in Argentina, Ecuador, Guatemala, Panama, Peru, and Uruguay. Conclusion Leukemia mortality is predicted to increase unless efforts are made to intervene. Interventions include addressing the inequities in health care diagnosing cases earlier,, avoiding treatment abandonment, and proper supportive care such as infection control programs will reduce the mortality in a great proportion.

scholarly journals Breast Cancer Mortality in the Americas and Australasia over the Period 1980–2017 with Predictions for 2025

Biology ◽  
2021 ◽  
Vol 10 (8) ◽  
pp. 814
Author(s):  
Cezary Wojtyla ◽  
Paola Bertuccio ◽  
Michal Ciebiera ◽  
Carlo La Vecchia
Keyword(s):  
Breast Cancer ◽  
Latin American ◽  
Cancer Mortality ◽  
Breast Cancer Mortality ◽  
Mortality Rates ◽  
World Health ◽  
Mortality Trends ◽  
The World ◽  
Substantial Progress ◽  
Health Organization

Substantial progress has been made in the diagnosis, management, and treatment of breast cancer over the last decades. This has affected mortality rates but has also led to inequality in epidemiological trends between different regions of the world. We extracted death certification data for breast cancer from the World Health Organization database. We analyzed trends in breast cancer mortality in selected countries from America, Asia, and Oceania over the 1980–2017 period and predicted numbers of deaths and rates for 2025. In North America, we observed decreased breast cancer mortality, reaching a rate of about 13/100,000 women in 2017. In Latin American countries, breast cancer mortality rates did not consistently decrease. The highest decreases in mortality were observed in Australia. Mortality trends in Asian countries remained among the lowest globally. We have predicted decreased mortality from breast cancer in 2025 for most of the analyzed countries. The epidemiological situation regarding breast cancer mortality is expected to change in the coming years. Advancements in diagnosis and treatment of breast cancer must be extended in various areas of the world to obtain global control of breast cancer mortality.

scholarly journals Trends of HIV-Related Cancer Mortality between 2001 and 2018: An Observational Analysis

2021 ◽  
Vol 6 (4) ◽  
pp. 213
Author(s):  
Chinmay Jani ◽  
Omar Al Omari ◽  
Harpreet Singh ◽  
Alexander Walker ◽  
Kripa Patel ◽  
...  
Keyword(s):  
Cancer Mortality ◽  
Population Data ◽  
Developed Countries ◽  
World Health ◽  
Mortality Data ◽  
Female Mortality ◽  
Mortality Trends ◽  
Male Mortality ◽  
The World ◽  
Health Organization

The burden of AIDS-defining cancers has remained relatively steady for the past two decades, whilst the burden of non-AIDS-defining cancer has increased. Here, we conduct a study to describe mortality trends attributed to HIV-associated cancers in 31 countries. We extracted HIV-related cancer mortality data from 2001 to 2018 from the World Health Organization Mortality Database. We computed age-standardized death rates (ASDRs) per 100,000 population using the World Standard Population. Data were visualized using Locally Weighted Scatterplot Smoothing (LOWESS). Data for females were available for 25 countries. Overall, there has been a decrease in mortality attributed to HIV-associated cancers among most of the countries. In total, 18 out of 31 countries (58.0%) and 14 out of 25 countries (56.0%) showed decreases in male and female mortality, respectively. An increasing mortality trend was observed in many developing countries, such as Malaysia and Thailand, and some developed countries, such as the United Kingdom. Malaysia had the greatest increase in male mortality (+495.0%), and Canada had the greatest decrease (−88.5%). Thailand had the greatest increase in female mortality (+540.0%), and Germany had the greatest decrease (−86.0%). At the endpoint year, South Africa had the highest ASDRs for both males (16.8/100,000) and females (19.2/100,000). The lowest was in Japan for males (0.07/100,000) and Egypt for females (0.028/100,000).

scholarly journals P087 Mortality trends from systemic lupus erythematosus in Cuba: 2001-2014

Rheumatology ◽  
2021 ◽  
Vol 60 (Supplement_1) ◽  
Author(s):  
Halbert Hernández Negrín
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Health Problem ◽  
Time Trends ◽  
Reference Population ◽  
World Health ◽  
Mortality Data ◽  
Systemic Lupus ◽  
Mortality Trends ◽  
Health Organization

Abstract Background/Aims  There is little research on the mortality of Cuban patients with systemic lupus erythematosus (SLE), with not enough impact to recognize SLE as a health problem in the country. Our aim was to identify time trends and geographic variability in the mortality of Cuban patients with SLE. Methods  Mortality data of decedents over 15 years old were retrieved from the Cuban Ministry of Public Health mortality database, based on International Classification of Disease (ICD), Tenth Revision (ICD-10, code M32). We computed age-standardized mortality rate (ASMR) for each year and province as the estimated number of deaths per million inhabitants and its 95% confidence interval (95% CI) using World Health Organization reference population. The 2001-2014 time trends were analyzed using Jointpoint software. Results  Between 2001 and 2014, 1,054 deaths from SLE were found, mostly women (89.0%), white (54.4%) with a median age of 43 years (interquartile range: 34-53). In 2014 the ASMR caused by SLE per million inhabitants was 14.4 (95% CI: 10.9 to 18.4) in women and 1.3 (95% CI: 0.5 to 3.2) in men. A growing time trend was identified in the ASMR by SLE throughout the period (average annual percentage change [AAPC]: 1.6; 95% CI: 0.6 to 2.6), highest in males (AAPC: 5.6; 95% CI: 1.7 to 9.7) than in females (AAPC: 1.2; 95% CI: 0.3 to 2.0). The highest mortality in women was concentrated in the provinces of Camagüey, Las Tunas and Granma, and in the case of men, in Havana and Ciego de Ávila. Conclusion  The variation in the magnitude of the risk of dying from SLE over time and geographic areas indicates the possible influence of biological, environmental, socioeconomic and health systems factors. The growing trend in SLE mortality in Cuba demands its recognition as an important health problem and immediate actions that help mitigate it. Disclosure  H. Hernández Negrín: None.

scholarly journals Prevalence of Psychological Disorders in Patients with COVID-19 Syndrome

2021 ◽  
Author(s):  
Farzin Bagheri Sheykhangafshe
Keyword(s):  
Psychological Health ◽  
Treatment Process ◽  
Psychological Disorders ◽  
Mortality Rates ◽  
World Health ◽  
Definitive Treatment ◽  
High Infection ◽  
The World ◽  
Health Organization

The coronavirus 2019 first broke out on December 17, 2019 in Wuhan, China, and on March 11, 2020, it was announced as a worldwide pandemic by the World Health Organization. Despite nutritious diets and promising vaccines, health tips such as wearing a mask, social distancing, home quarantine, and not traveling are still the best ways to control the spread of COVID-19.While the widespread prevalence of COVID-19, severe restrictions, lack of definitive treatment, and the high infection and mortality rates have led to cognitive psychological disorders among the general population of the world. One of the epidemic consequences of COVID-19 syndrome in people who have defeated the coronavirus was psychological disorders. Considering the role of mental health in boosting the immune system, improving the effectiveness of the COVID-19 vaccine and accelerating the treatment process of patients, it is suggested that in the post-COVID era, more attention be paid to the psychological health of the community.

scholarly journals Development of a public geographical information system-based website to follow the impact of control activities of soil-transmitted helminths in endemic countries

2021 ◽  
Vol 16 (2) ◽  
Author(s):  
Maria Paola Maurelli ◽  
Paola Pepe ◽  
Antonio Montresor ◽  
Denise Mupfasoni ◽  
Martina Nocerino ◽  
...  
Keyword(s):  
Neglected Tropical Diseases ◽  
Mortality Rates ◽  
Geographical Information ◽  
World Health ◽  
High Morbidity ◽  
Preventive Chemotherapy ◽  
The World ◽  
Pharmaceutical Industries ◽  
Health Organization ◽  
The Impact

Soil-transmitted helminth (STH) infections are among the most common neglected tropical diseases worldwide causing high morbidity and mortality rates in endemic areas. Preventive chemotherapy (PC) programmes and health education are recommended by the World Health Organization (WHO) to reduce the impact of STH in endemic countries. Following our role as WHO collaborating centre (WHO CC ITA-116), we have developed a WebGIS and a dataset to support PC programmes to monitor the impact of STH control. This vHealth presentation shows the potentiality of these tools in improving communication among WHO’s regional and country offices, Ministries of Health, pharmaceutical industries and other partners.

Importance of Using Standardized Birth Weight Increments to Report Neonatal Mortality Data

PEDIATRICS ◽  
1986 ◽  
Vol 78 (1) ◽  
pp. 144-145
Author(s):  
Marcus C. Hermansen ◽  
Shirin Hasan
Keyword(s):  
Birth Weight ◽  
World Health Organization ◽  
Neonatal Mortality ◽  
World Health ◽  
Mortality Data ◽  
Weight Group ◽  
Mortality Statistics ◽  
Future Studies ◽  
The World ◽  
Health Organization

Neonatal mortality statistics are frequently reported in 100-g increments of birth weight. We tabulated our mortality statistics using two methods of incrementation: 500 to 599 g, 600 to 699 g, 700 to 799 g, etc. (method A) and 501 to 600 g, 601 to 700 g, 701 to 800 g, etc (method B). In each 100-g weight group, the mortality was less using method B. The average reduction in mortality using method B was 4.1%. Use of the two different methods creates difficulty in making meaningful comparisons of various published reports. We recommend that all future studies use method A, as that method is more consistent with previous recommendations of the World Health Organization.

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