scholarly journals Leukemia mortality in children from Latin America: Trends and predictions to 2030

2020 ◽  
Author(s):  
J. Smith Torres-Roman ◽  
Bryan Valcarcel ◽  
Pedro Guerra-Canchari ◽  
Camila Alves Dos Santos ◽  
Isabelle Ribeiro Barbosa ◽  
...  
Keyword(s):  
Latin American ◽  
Mortality Rates ◽  
World Health ◽  
Mortality Data ◽  
Mortality Trends ◽  
Annual Percent Change ◽  
Control Programs ◽  
Standard Population ◽  
Health Organization ◽  
Treatment Abandonment

Abstract Background Reports suggest that Latin American and Caribbean (LAC) countries have not achieved the downward mortality trends in leukemia seen in other countries. However, updated trends remain largely unknown in the region. Given that leukemia is the leading cause of cancer-related death in LAC children, we aimed to evaluate mortality trends in children (0-14y) from 15 LAC countries for the period 2000–2017 and to predict mortality until 2030. Methods We retrieved cancer mortality data through the World Health Organization Mortality Database. Age-standardized (world standard population) rates were computed for LAC countries. Joinpoint regression analysis was used to examine trends in the mortality rates of leukemia and provide an estimated annual percent change (EAPC). Nordpred was utilized for the calculation of predictions until 2030. Results Between 2013 and 2017, the highest mortality rates were reported in Venezuela, Ecuador, Nicaragua, Mexico, and Peru. Upward mortality trends were reported in Nicaragua (EAPC by 1.2% in boys, and EAPC by 2.0% in girls), Panama (EAPC by 1.8% in boys, and by 2.7% in girls), and Peru (EAPC by 1.4% in both sexes). Puerto Rico experienced large declines in mortality among both boys (APC by − 9.7%), and girls (EAPC by − 6.0%). Forecasting models predicted that leukemia mortality between 2015 and 2030, will increase in Argentina, Ecuador, Guatemala, Panama, Peru, and Uruguay. Conclusion Leukemia mortality is predicted to increase unless efforts are made to intervene. Interventions include addressing the inequities in health care diagnosing cases earlier,, avoiding treatment abandonment, and proper supportive care such as infection control programs will reduce the mortality in a great proportion.

scholarly journals Leukemia mortality in children from Latin America: Trends and predictions to 2030

2020 ◽  
Author(s):  
J. Smith Torres-Roman ◽  
Bryan Valcarcel ◽  
Pedro Guerra-Canchari ◽  
Camila Alves Dos Santos ◽  
Isabelle Ribeiro Barbosa ◽  
...  
Keyword(s):  
Latin American ◽  
Mortality Rates ◽  
World Health ◽  
Mortality Data ◽  
Mortality Trends ◽  
Annual Percent Change ◽  
Universal Healthcare ◽  
The World ◽  
Health Organization ◽  
Universal Healthcare Coverage

Abstract Background: Reports suggest that Latin American and Caribbean (LAC) countries have not reduced in leukemia mortality compared to high-income countries. However, updated trends remain largely unknown in the region. Given that leukemia is the leading cause of cancer-related death in LAC children, we evaluated mortality trends in children (0-14y) from 15 LAC countries for the period 2000-2017 and predicted mortality to 2030.Methods: We retrieved cancer mortality data using the World Health Organization Mortality Database. Mortality rates (standardized to the world standard SEGI population) were analyzed for 15 LAC countries. We evaluated the average mortality rates for the last 5 years (2013-2017). Joinpoint regression analysis was used to evaluate leukemia mortality trends and provide an estimated annual percent change (EAPC). Nordpred was utilized for the calculation of predictions until 2030.Results: Between 2013 and 2017, the highest mortality rates were reported in Venezuela, Ecuador, Nicaragua, Mexico, and Peru. Upward mortality trends were reported in Nicaragua (EAPC by 2.9% in boys, and EAPC by 2.0% in girls), and Peru (EAPC by 1.4% in both sexes). Puerto Rico experienced large declines in mortality among both boys (EAPC by −9.7%), and girls (EAPC by −6.0%). Leukemia mortality will increase in Argentina, Ecuador, Guatemala, Panama, Peru, and Uruguay by 2030.Conclusion: Leukemia mortality is predicted to increase in some LAC countries by 2030. Interventions to prevent this outcome should be tailor to reduce the socioeconomic inequalities and ensure universal healthcare coverage.

scholarly journals Leukemia mortality in children from Latin America: trends and predictions to 2030

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
J. Smith Torres-Roman ◽  
Bryan Valcarcel ◽  
Pedro Guerra-Canchari ◽  
Camila Alves Dos Santos ◽  
Isabelle Ribeiro Barbosa ◽  
...  
Keyword(s):  
Latin American ◽  
Mortality Rates ◽  
World Health ◽  
Mortality Data ◽  
Mortality Trends ◽  
Annual Percent Change ◽  
Universal Healthcare ◽  
The World ◽  
Health Organization ◽  
Universal Healthcare Coverage

Abstract Background Reports suggest that Latin American and Caribbean (LAC) countries have not reduced leukemia mortality compared to high-income countries. However, updated trends remain largely unknown in the region. Given that leukemia is the leading cause of cancer-related death in LAC children, we evaluated mortality trends in children (0-14y) from 15 LAC countries for the period 2000–2017 and predicted mortality to 2030. Methods We retrieved cancer mortality data using the World Health Organization Mortality Database. Mortality rates (standardized to the world standard SEGI population) were analyzed for 15 LAC countries. We evaluated the average mortality rates for the last 5 years (2013–2017). Joinpoint regression analysis was used to evaluate leukemia mortality trends and provide an estimated annual percent change (EAPC). Nordpred was utilized for the calculation of predictions until 2030. Results Between 2013 and 2017, the highest mortality rates were reported in Venezuela, Ecuador, Nicaragua, Mexico, and Peru. Upward mortality trends were reported in Nicaragua (EAPC by 2.9% in boys, and EAPC by 2.0% in girls), and Peru (EAPC by 1.4% in both sexes). Puerto Rico experienced large declines in mortality among both boys (EAPC by − 9.7%), and girls (EAPC by − 6.0%). Leukemia mortality will increase in Argentina, Ecuador, Guatemala, Panama, Peru, and Uruguay by 2030. Conclusion Leukemia mortality is predicted to increase in some LAC countries by 2030. Interventions to prevent this outcome should be tailor to reduce the socioeconomic inequalities and ensure universal healthcare coverage.

scholarly journals Breast Cancer Mortality in the Americas and Australasia over the Period 1980–2017 with Predictions for 2025

Biology ◽  
2021 ◽  
Vol 10 (8) ◽  
pp. 814
Author(s):  
Cezary Wojtyla ◽  
Paola Bertuccio ◽  
Michal Ciebiera ◽  
Carlo La Vecchia
Keyword(s):  
Breast Cancer ◽  
Latin American ◽  
Cancer Mortality ◽  
Breast Cancer Mortality ◽  
Mortality Rates ◽  
World Health ◽  
Mortality Trends ◽  
The World ◽  
Substantial Progress ◽  
Health Organization

Substantial progress has been made in the diagnosis, management, and treatment of breast cancer over the last decades. This has affected mortality rates but has also led to inequality in epidemiological trends between different regions of the world. We extracted death certification data for breast cancer from the World Health Organization database. We analyzed trends in breast cancer mortality in selected countries from America, Asia, and Oceania over the 1980–2017 period and predicted numbers of deaths and rates for 2025. In North America, we observed decreased breast cancer mortality, reaching a rate of about 13/100,000 women in 2017. In Latin American countries, breast cancer mortality rates did not consistently decrease. The highest decreases in mortality were observed in Australia. Mortality trends in Asian countries remained among the lowest globally. We have predicted decreased mortality from breast cancer in 2025 for most of the analyzed countries. The epidemiological situation regarding breast cancer mortality is expected to change in the coming years. Advancements in diagnosis and treatment of breast cancer must be extended in various areas of the world to obtain global control of breast cancer mortality.

scholarly journals P087 Mortality trends from systemic lupus erythematosus in Cuba: 2001-2014

Rheumatology ◽  
2021 ◽  
Vol 60 (Supplement_1) ◽  
Author(s):  
Halbert Hernández Negrín
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Health Problem ◽  
Time Trends ◽  
Reference Population ◽  
World Health ◽  
Mortality Data ◽  
Systemic Lupus ◽  
Mortality Trends ◽  
Health Organization

Abstract Background/Aims  There is little research on the mortality of Cuban patients with systemic lupus erythematosus (SLE), with not enough impact to recognize SLE as a health problem in the country. Our aim was to identify time trends and geographic variability in the mortality of Cuban patients with SLE. Methods  Mortality data of decedents over 15 years old were retrieved from the Cuban Ministry of Public Health mortality database, based on International Classification of Disease (ICD), Tenth Revision (ICD-10, code M32). We computed age-standardized mortality rate (ASMR) for each year and province as the estimated number of deaths per million inhabitants and its 95% confidence interval (95% CI) using World Health Organization reference population. The 2001-2014 time trends were analyzed using Jointpoint software. Results  Between 2001 and 2014, 1,054 deaths from SLE were found, mostly women (89.0%), white (54.4%) with a median age of 43 years (interquartile range: 34-53). In 2014 the ASMR caused by SLE per million inhabitants was 14.4 (95% CI: 10.9 to 18.4) in women and 1.3 (95% CI: 0.5 to 3.2) in men. A growing time trend was identified in the ASMR by SLE throughout the period (average annual percentage change [AAPC]: 1.6; 95% CI: 0.6 to 2.6), highest in males (AAPC: 5.6; 95% CI: 1.7 to 9.7) than in females (AAPC: 1.2; 95% CI: 0.3 to 2.0). The highest mortality in women was concentrated in the provinces of Camagüey, Las Tunas and Granma, and in the case of men, in Havana and Ciego de Ávila. Conclusion  The variation in the magnitude of the risk of dying from SLE over time and geographic areas indicates the possible influence of biological, environmental, socioeconomic and health systems factors. The growing trend in SLE mortality in Cuba demands its recognition as an important health problem and immediate actions that help mitigate it. Disclosure  H. Hernández Negrín: None.

Mortality of Testicular Cancer in East and West Germany 20 Years after Reunification: A Gap Not Closed Yet

2015 ◽  
Vol 95 (2) ◽  
pp. 160-166 ◽  
Author(s):  
Andreas Stang ◽  
Freddie Bray ◽  
Klaus-Peter Dieckmann ◽  
Joannie Lortet-Tieulent ◽  
Carsten Rusner
Keyword(s):  
Testicular Cancer ◽  
Cancer Mortality ◽  
East Germany ◽  
Mortality Rates ◽  
West Germany ◽  
Mortality Data ◽  
Mortality Trends ◽  
Male Population ◽  
East And West Germany ◽  
Standard Population

Background: The decline of testicular cancer mortality in East Germany began in the 1980s, about 10 years later than that recorded in West Germany. We aimed at providing up-to-date time trends of testicular cancer mortality rates in Germany. Material and Methods: Mortality data from East Germany (1971-2010) and West Germany (1954-2010) were provided by the Federal Bureau of Statistics. We estimated age-specific and age-standardized mortality rates using the World Standard Population. Results: Despite the declining trend in the 2000s, the mortality rates of testicular cancer remained higher in East than in West Germany. These rates were 5.5 and 2.6 per million person-years in 2010, respectively. Age-specific mortality trends by period and birth cohort showed that the mortality decline was larger among younger (15-44 years) than elderly men. Conclusion: The mortality of testicular cancer is still higher in East than West Germany. Despite very similar densities of hospital beds, urologists and oncologist per million male population in both parts of Germany, we hypothesized that a paucity of centers of expertise for treating testicular cancers in the East could account for this particular pattern.

scholarly journals Cervical cancer mortality in Peru: regional trend analysis from 2008–2017

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
J. Smith Torres-Roman ◽  
Luz Ronceros-Cardenas ◽  
Bryan Valcarcel ◽  
Miguel A. Arce-Huamani ◽  
Janina Bazalar-Palacios ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Spatial Analysis ◽  
Latin American ◽  
Cancer Mortality ◽  
Care Delivery ◽  
Mortality Rates ◽  
Mortality Trends ◽  
Annual Percent Change ◽  
North East ◽  
Cervical Cancer Mortality

Abstract Background Cervical cancer is the third leading cause of cancer-related death among Latin American women. Peru has the sixth highest mortality rate for cervical cancer in the region with regional variations. We aimed to determine overall and regional cervical cancer mortality rates and trends in Peru between 2008 and 2017. Methods We performed an ecological study on the number of deaths by cervical cancer in Peru. Deaths were extracted from the Peruvian Ministry of Health mortality database. Age-standardized mortality rates (ASMR) were estimated per 100,000 women-years using the world standard Segi population. We computed mortality trends using the Joinpoint regression program, estimating the annual percent change (APC). For spatial analysis, GeoDA software was used. Results Peru showed downward trends in the last decade (from 11.62 in 2008 to 9.69 in 2017 (APC = − 2.2, 95% CI: − 4.3, − 0.1, p < 0.05). According to regional-specific analysis, the highest ASMR was in the rainforest region, although this declined from 34.16 in 2008 to 17.98 in 2017 (APC = − 4.3, 95% CI: − 7.2, − 1.3, p < 0.01). Concerning spatial analysis and clustering, the mortality rates from 2008 to 2017 showed a positive spatial autocorrelation and significant clustering (Moran’s I: 0.35, p < 0.001) predominantly in the neighboring North-East departments (Loreto, Ucayali, and San Martin). Conclusions Although mortality trends in the entire population are decreasing, mortality rates remain very high, mainly in the rainforest region. Our results encourage a need for further development and improvement of the current health care delivery system in Peru.

scholarly journals Changes in drowning mortality rates and quality of reporting from 2004–2005 to 2014–2015: a comparative study of 61 countries

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Ching-Yi Lin ◽  
Liang-Yi Wang ◽  
Tsung-Hsueh Lu
Keyword(s):  
Death Certificate ◽  
Mortality Rates ◽  
World Health ◽  
Mortality Data ◽  
Specific Information ◽  
Quality Of Reporting ◽  
The Past ◽  
Notable Increase ◽  
Health Organization

Abstract Background This study assessed international variations in changes in drowning mortality rates and the quality of reporting specific information in death certificates over the past decade. Methods Drowning mortality data of 61 countries were extracted from the World Health Organization Mortality Database. We calculated the percentage change (PC) in age-standardized drowning mortality rates and percentage of drowning deaths reported with unspecified codes between 2004 and 2005 and 2014–2015. Results Of the 61 countries studied, 50 exhibited a reduction in drowning mortality rates from 2004 to 2005 to 2014–2015. Additionally, five countries—Lithuania, Moldova, Kyrgyzstan, Romania, and El Salvador—with a high mortality rate in 2004–2005 (> 40 deaths per 100,000) showed improvement (PC < − 32%). By contrast, four countries—South Africa, Guyana, Morocco, and Guatemala—exhibited a more than twofold increase in mortality rates. Regarding the quality of reporting, 34 countries exhibited a decrease in the percentage of unspecified codes. Additionally, three countries—Paraguay, Serbia, and Croatia—with moderate and high percentages of unspecified codes (> 40%) exhibited a marked reduction (PC < − 60%), whereas three countries—Malaysia, Belgium, and Nicaragua—exhibited a notable increase. Conclusions Large international variations in the extent of changes in drowning mortality rates and the quality of reporting specific information on the death certificate were observed during the study period.

scholarly journals The impact of inequalities and health expenditure on mortality due to oral and oropharyngeal cancer in Brazil

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Amanda Ramos da Cunha ◽  
Alessandro Bigoni ◽  
José Leopoldo Ferreira Antunes ◽  
Fernando Neves Hugo
Keyword(s):  
Health Services ◽  
Oropharyngeal Cancer ◽  
Government Expenditure ◽  
Health Spending ◽  
Mortality Rates ◽  
Mortality Data ◽  
Mortality Trends ◽  
Annual Percent Change ◽  
The Government ◽  
The Impact

AbstractThis study aims to assess the magnitude and trend of mortality rates due to oral (OC) and oropharyngeal cancer (OPC) in the 133 Intermediate Geographic Regions (IGR) of Brazil between 1996 and 2018 and to analyze its association with sociodemographic variables and provision of health services. It also aims to compare the trend of mortality from neoplasms that have been reported as associated with HPV (OPC) with the trend of neoplasms that have been reported as not associated with HPV (OC). We obtained mortality data from the Mortality Information System in Brazil and analyzed the trends using the Prais-Winsten method. Then, we assessed the relationship between mortality trends and socioeconomic, health spending, and health services provision variables. The median of the annual percent change of the country’s mortality rates was 0.63% for OC and 0.83% for OPC. Trends in mortality in the IGRs correlated significantly with the Human Development Index and government expenditure on ambulatory health care and hospitalizations. Mortality from both types of cancer decreased in those IGR in which the government spent more on health and in the more socioeconomically developed ones. This study found no epidemiological indication that HPV plays the leading etiological factor in OPC in Brazil.

scholarly journals Prostate cancer mortality trends in Argentina 1986-2006: an age-period-cohort and joinpoint analysis

2011 ◽  
Vol 27 (1) ◽  
pp. 123-130 ◽  
Author(s):  
Camila Niclis ◽  
Sonia A. Pou ◽  
Rubén H. Bengió ◽  
Alberto R. Osella ◽  
María del Pilar Díaz
Keyword(s):  
Prostate Cancer ◽  
Cancer Mortality ◽  
Time Trends ◽  
World Health ◽  
Mortality Data ◽  
Birth Cohorts ◽  
Mortality Trends ◽  
Prostate Cancer Mortality ◽  
Increased Risk ◽  
Health Organization

The aim of this study was to give an overview of the magnitude, variation by age and time trends in the rates of prostate cancer mortality in Córdoba province and in Argentina as a whole from 1986 to 2006. Mortality data were provided by the Córdoba Ministry of Health and the World Health Organization cancer mortality database. Prostate cancer mortality time trends were analyzed using joinpoint analysis and age-period-cohort models. In Argentina prostate cancer age-standardized mortality rates rose by 1% and 3.4% per year from 1986 to 1992 and from 1992 to 1998 respectively. There was a decreasing trend (-1.6%) for Argentina from 1998 and Córdoba (-1.9%) from 1995. Age-period-cohort models for the country and the province showed a strong age effect. In the country there was an increased risk in the 1996-2000 period, whereas there was decreased risk for birth cohorts since 1946, principally in Córdoba. A decreasing trend in prostate cancer mortality was found in Córdoba as well as in Argentina, which might be attributed to the improvement in treatment in this country.

scholarly journals Incidence and mortality by larynx cancer in Central and South America

2021 ◽  
Vol 42 ◽  
Author(s):  
Suellen Nadine de Lima Costa ◽  
Fábia Cheyenne Gomes de Morais Fernandes ◽  
Dyego Leandro Bezerra de Souza ◽  
Héllyda de Souza Bezerra ◽  
Emelynne Gabrielly de Oliveira Santos ◽  
...  
Keyword(s):  
Laryngeal Cancer ◽  
Incidence Rates ◽  
World Health ◽  
International Agency ◽  
Mortality Data ◽  
Mortality Trends ◽  
Incidence Data ◽  
Incidence And Mortality ◽  
Mortality Ratio ◽  
Health Organization

ABSTRACT Objective: To describe how the incidence and mortality trends for laryngeal cancer in South and Central American countries. Methods: Time series study, with incidence data from the International Agency for Research on Cancer, from 1990 to 2012 and mortality data from 17 countries of the World Health Organization, from 1995 to 2013. The trend was analyzed by Joinpoint regression. Results: The highest incidence rate for laryngeal cancer was in Brazil, with 5.9 new cases per 100,000 men, and the highest mortality rate in Uruguay with 4.2 deaths per 100,000 men. The incidence ratio between genders ranged from 4: 1 (Colombia) to 12: 1 (Ecuador). The mortality ratio between the sexes ranged from 4: 1 (Peru) to 14: 1 (Uruguay). Conclusion: Most countries had low incidence rates and reduced mortality in Latin America.

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