scholarly journals Follow-Up Study of Echocardiography in 38 Children With Kawasaki Disease Complicated by Heart Lesion

Author(s):  
Tingting Liu ◽  
Weina Hou ◽  
Liandi Xu ◽  
Tianhua Li ◽  
Baihong Qiu

Abstract Background: The most common and most serious complication of Kawasaki disease (KD)is heart lesion(HL), which is the main cause of childhood acquired HL.Objective: Use echocardiography to study the HL recovery of children with KD complicated by HL, and provide an important theoretical basis for the prognosis of KD complicated by HL.Methods: Using prospective research methods, 38 children with KD complicated by HL were followed up for echocardiographic examination, and the longest examination time was one year. And carry on statistical analysis to the inspection data.Results: In 38 children with KD complicated by HL, 36 cases of coronary artery lesion (CAL), including 29 cases of coronary artery dilation(CAD), 7 cases of coronary artery stenosis(CAS), and 2 cases of simple pericardial effusion without CAL. CAL complicated with valve regurgitation in 4 cases, pericardial effusion in 3 cases, and left ventricular enlargement in 4 cases. In about 3 weeks, most of the pericardial effusion and mild CAD recovered. At 3 months, except for a few severe CAL, heart valve regurgitation and left ventricular enlargement all recovered. The recovery of moderate CAD was slow. One case still failed to return to normal after 1 year, but the coronary artery diameter gradually decreased.Conclusion: Kawasaki disease complicated by heart lesion mainly affects the coronary arteries, and the main manifestation is expansion. The more the expansion, the slower the recovery.

Author(s):  
Akshar Jaglan ◽  
Tarek Ajam ◽  
Steven C Port ◽  
Tanvir Bajwa ◽  
A Jamil Tajik

Abstract Background Coronary artery ectasia (CAE) is a rare anomaly that can present at any age. Predisposing risk factors include Kawasaki disease in a younger population and atherosclerosis in the older generation. We present a unique case of the management of a young woman diagnosed with multivessel CAE with aneurysmal changes in the setting of acute coronary syndrome and subsequently during pregnancy. Case summary A 23-year-old woman presented with acute onset chest pain. Electrocardiogram revealed no ischaemic changes; however, troponin I peaked at 16 ng/mL (reference range 0–0.04 ng/mL). Echocardiogram showed apical dyskinesis with preserved left ventricular ejection fraction. Coronary angiography showed multivessel CAE along with significant thrombus burden in an ectatic lesion of the left anterior descending artery. Since the patient was haemodynamically stable, conservative management with dual antiplatelet therapy and anticoagulation was started. On follow-up, coronary computed tomographic angiogram illustrated resolution of the coronary thrombi and echocardiogram showed improvement to the apical dyskinesis. It was presumed that Kawasaki disease was the most likely aetiology of her disease. Subsequently the patient reported that, contrary to medical advice, she was pregnant, adding another layer of complexity to her case. Discussion Coronary artery ectasia can be discovered as an incidental finding or can present with an acute coronary syndrome. Management is challenging in the absence of randomized trials and large-scale data. Treatment options include medications, percutaneous intervention, and surgical revascularization. Close surveillance is required in these patients to assess progression of disease. Here we discuss treatment options during acute coronary syndrome and pregnancy.


2018 ◽  
Vol 51 (6) ◽  
pp. 1178
Author(s):  
Nelson Samesima ◽  
Pedro Augusto Moraes ◽  
Tatyane Saito ◽  
Horacio Pereira Filho ◽  
Mirella Facin ◽  
...  

Author(s):  
Alexander K. C. Leung ◽  
William Lane M. Robson ◽  
Carsten Büning ◽  
Johann Ockenga ◽  
Janine Büttner ◽  
...  

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
L A Pereira de Sousa ◽  
V Tostes Carvalho ◽  
W Wagner de Oliveira ◽  
M V Lins de Barros ◽  
T Guimarães Teixeira ◽  
...  

Abstract Background The use of tele-echocardiograms could be useful for improving access of patients to echocardiographic evaluation in places where there is a shortage of trained physicians. It was evaluated the agreement between a physician sonographer and another health professional with basic training to acquire transthoracic images, assessed by a remote echocardiographer. Methods 174 patients underwent echocardiography by a physician level III training in Echo. A moving image protocol (MPEG format, 3 cycles for each image) was stored: 2D parasternal long axis, apical four chambers with and without color. Soon after, a nurse with 20 hours of training in Echo, unaware of the result of the report, acquired the same protocol. The exams were randomized and sent to a remote observer, another echocardiographer level III, blinded to the sonographer's status, to recognize the presence of the any of the following abnormalities: left ventricular enlargement, hypertrophy and systolic dysfunction; right ventricular enlargement, left atrium enlargement and left sided valvopathy at least moderate. Agreement was evaluated by kappa concordance. Results It was analyzed 108 females and 66 males, median age= 61 y [P.25=50-P.75=72]; LV ejection fraction= 64 % [58-69] and body mass index= 27.6 kg/m2 [24.5-32.5]. There was a good concordance between the evaluators. All the indices analyzed showed agreement above 0.55 and statistic significance (left ventricular enlargement - 0.84; left ventricular hypertrophy - 0.84; systolic left ventricular dysfunction - 0.82; right ventricle enlargement - 0.72; left atrial enlargement - 0.80; valvopathy - 0.56). Conclusions The image acquisition by a tele-echocardiogram screening may be acquired by non-physician professionals with minimum training. Key messages Echocardiography. Remote.


2019 ◽  
Vol 09 (01) ◽  
pp. 060-063 ◽  
Author(s):  
Yilmaz Yozgat ◽  
Selcuk Uzuner ◽  
Aysegul Dogan Demir ◽  
Mustafa Ogur ◽  
Can Yilmaz Yozgat ◽  
...  

AbstractWe report a 13-year-old boy who (initially) had symptoms of toxic shock-like syndrome and mumps. Then, the patient was hospitalized in the pediatric intensive care unit (PICU) because of his ongoing hemodynamic instability (low blood pressure of 70/30 mm Hg and capillary refill time of > 4 seconds). During his stay in the PICU, the patient was treated with fluid resuscitation and vasoactive infusion and at the same time was diagnosed with Kawasaki disease shock syndrome (KDSS), when giant right coronary artery aneurysms were detected on echocardiographic examination. This case illustrates the risk of KDSS in patient who carries both parotitis and toxic shock-like syndrome. The clinicians should be cautious about detecting any types of coronary artery aneurysms in such patients. This is the first case of KDSS associated with parotitis reported in the literature.


2019 ◽  
Vol 7 (10) ◽  
pp. 4153-4165 ◽  
Author(s):  
Yusuke Kambe ◽  
Tetsuji Yamaoka

Random collagen fiber networks formed by a slowly degrading silk fibroin hydrogel injection prevented left ventricular enlargement after myocardial infarction.


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