scholarly journals Telephone-Delivered Dietary Intervention in Patients with Age-Related Macular Degeneration: 3-Months Post-Intervention Findings of a Randomised Controlled Trial

2020 ◽  
Author(s):  
Diana Tang ◽  
Paul Mitchell ◽  
George Burlutsky ◽  
Gerald Liew ◽  
Victoria M. Flood ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Controlled Trial ◽  
Age Related Macular Degeneration ◽  
Leafy Vegetables ◽  
Dietary Intakes ◽  
Dietary Recommendations ◽  
Post Intervention ◽  
Green Leafy Vegetables ◽  
Age Related ◽  
Dark Green

Abstract Background: There is an evidence-practice gap between the dietary recommendations for age-related macular degeneration (AMD) presented in the literature and those practiced by patients. This study reports on the 3-months post-intervention results of a randomised controlled trial (RCT) evaluating telephone-delivered dietary counselling aiming to improve dietary behaviors among patients with AMD.Methods: 155 AMD patients (57% female, aged 78 ± 8 years; control: 78, intervention: 77), primarily residing in New South Wales, Australia were recruited into the RCT at baseline. Participants completed a baseline questionnaire and short dietary questionnaire for age-related macular degeneration (SDQ-AMD). The intervention included an evidence-based nutrition resource and four monthly calls with a dietitian in addition to usual care; the control arm only received usual care. Immediately post-intervention, participants in the intervention arm were invited to repeat the SDQ-AMD and complete a feedback form. At 3-months post-intervention, all participants were invited to repeat the SDQ-AMD. Statistical analyses included t-tests and McNemar’s test to determine change in dietary intakes and proportion of participants meeting the dietary recommendations, respectively; level of significance for all statistical analyses was p <0.05. Descriptive statistics were used to describe adherence to and acceptability of the intervention.Results: At 3-months post-intervention compared to baseline, there were significant improvements within the intervention arm including increased intakes (mean serves ± SE) of dark green leafy vegetables (0.99 ± 0.17 vs 1.71 ± 0.22; p = 0.003) and legumes (0.69 ± 0.10 vs 1.12 ± 0.16; p = 0.02), and reduced intakes of specified discretionary foods (8.31 ± 0.76 vs 6.54 ± 0.58, p = 0.01). Between study arms, intakes of nuts were significantly higher in the intervention arm (control: 2.71 ± 0.32 vs intervention: 3.96 ± 0.51; p = 0.04) at 3-months post-intervention. Overall feedback about the intervention was positive, with all completers (n = 74) finding the program worthwhile and 98.7% (n = 73) indicating they would recommend it to others. Conclusion: This novel intervention was well-received and significantly improved the dietary intakes of dark green leafy vegetables, legumes and discretionary foods within the intervention arm.Trial registration: Australian New Zealand Clinical Trials Registry; ACTRN12618000527268; registered 10 April 2018.

scholarly journals Telephone-Delivered Dietary Intervention in Patients with Age-Related Macular Degeneration: 3-Month Post-Intervention Findings of a Randomised Controlled Trial

Nutrients ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 3083
Author(s):  
Diana Tang ◽  
Paul Mitchell ◽  
Gerald Liew ◽  
George Burlutsky ◽  
Victoria M. Flood ◽  
...  
Keyword(s):  
Randomised Controlled Trial ◽  
Macular Degeneration ◽  
Controlled Trial ◽  
Age Related Macular Degeneration ◽  
Leafy Vegetables ◽  
Secondary Outcome ◽  
Post Intervention ◽  
Age Related ◽  
Significant Difference ◽  
Randomised Controlled

There is an evidence–practice gap between the dietary recommendations for age-related macular degeneration (AMD) presented in the literature and those practiced by patients. This study reports on the 3-month post-intervention results of a randomised controlled trial (RCT) evaluating telephone-delivered counselling to improve dietary behaviours among AMD patients. A total of 155 AMD patients (57% female, aged 78 ± 8 years; control: 78, intervention: 77), primarily residing in New South Wales, Australia, were recruited. Participants completed a baseline questionnaire and a short dietary questionnaire (SDQ-AMD). The intervention included an evidence-based nutrition resource and four monthly calls with a dietitian. Immediately post-intervention, intervention participants repeated the SDQ-AMD and completed a feedback form. At 3 months post-intervention, both study arms repeated the SDQ-AMD. Statistical analyses included t-tests and McNemar’s test. Intervention participants reported satisfaction with the tailored phone calls, nutrition resource and nutrition education provided. At 3 months post-intervention, there was no statistically significant difference between study arms in the proportion of participants meeting the dietary goals nor in intake (mean servings ± SE) of total vegetables (primary outcome) and other key food groups; however, there was a significantly higher intake of nuts (secondary outcome) (3.96 ± 0.51 vs. 2.71 ± 0.32; p = 0.04) among participants in the intervention versus control group. Within the intervention arm, there were also significant improvements in intakes of the following secondary outcomes: dark green leafy vegetables (0.99 ± 0.17 vs. 1.71 ± 0.22; p = 0.003) and legumes (0.69 ± 0.10 vs. 1.12 ± 0.16; p = 0.02) and intake of sweets and processed/prepared foods (8.31 ± 0.76 vs. 6.54 ± 0.58, p = 0.01). In summary, although there were few dietary differences between study arms at 3 months post-intervention, the intervention involving four monthly calls was acceptable and helpful to the participants. This type of intervention therefore has the potential to provide people with AMD the needed support for improving their nutrition knowledge and dietary practices, especially if continued over a longer period.

scholarly journals Dietary intervention in patients with age-related macular degeneration: protocol for a randomised controlled trial

BMJ Open ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. e024774 ◽  
Author(s):  
Diana Tang ◽  
Paul Mitchell ◽  
Victoria Flood ◽  
Annette Kifley ◽  
Alison Hayes ◽  
...  
Keyword(s):  
Randomised Controlled Trial ◽  
Macular Degeneration ◽  
Dietary Intervention ◽  
Controlled Trial ◽  
Empirical Evaluation ◽  
Age Related Macular Degeneration ◽  
Dietary Recommendations ◽  
Phone Calls ◽  
Age Related ◽  
Randomised Controlled

IntroductionAge-related macular degeneration (AMD) is a leading cause of blindness. After smoking, nutrition is the key modifiable factor in reducing AMD incidence and progression, and no other preventative treatments are currently available. At present, there is an evidence–practice gap of dietary recommendations made by eye care practitioners and those actually practised by patients with AMD. To address this gap, a telephone-delivered dietary intervention tailored to patients with AMD will be piloted. The study aims to improve dietary intake and behaviours in patients with AMD. This type of nutrition-focused healthcare is currently not considered in the long-term management of AMD and represents the first empirical evaluation of a telephone-supported application encouraging adherence to dietary recommendations for AMD.Methods and analysis140 participants with AMD will be recruited for this randomised controlled trial. Those lacking English fluency; unwilling to engage in the intervention or provide informed consent were excluded. Following the completion of the baseline questionnaire, participants will be randomised into one of two arms: intervention or wait-list control (70 each in the intervention and control groups). Intervention participants will receive a detailed mail-delivered workbook containing information on healthy eating behaviours that promote optimal macular health, as well as scheduled phone calls over 4 months from an accredited practising dietitian. Descriptive statistics and multivariate stepwise linear regressions analyses will be used to summarise and determine the changes in dietary intakes, respectively. Economic analysis will be conducted to determine intervention feasibility and possibility of a large-scale rollout.Ethics and disseminationThe study was approved by the University of Sydney Human Research Ethics Committee (HREC) (Reference: HREC 2018/219). Study findings will be disseminated via presentations at national/international conferences and peer-reviewed journal articles.Trial registration numberACTRN12618000527268; Pre-results.

Lutein as a Contributing Modulator of Age-related Macular Degeneration

2012 ◽  
Vol 05 (01) ◽  
pp. 57
Author(s):  
Clyde Schultz ◽  
Keyword(s):  
Risk Factors ◽  
Body Weight ◽  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Leafy Vegetables ◽  
Green Leafy Vegetables ◽  
Age Related ◽  
History Of ◽  
Available Information ◽  
Oral Supplement

Lutein is a small-molecule carotenoid that has been studied with varying degrees of interest in both general nutrition and ophthalmology. This molecule is derived from green leafy vegetables (as well as commercially available dietary supplements) and has been postulated to act as a modulator in retinal health, specifically as a factor in the prevention of macular degeneration. The available clinical data do not suggest that lutein or the carotenoid zeaxanthin have any inherent toxicity. The presence of either or both has been linked to the prevention, but not necessarily the treatment, of macular degeneration. The available information may suggest that lutein intake as an oral supplement, coupled with awareness (and where possible modulation) of certain risk factors such as elevated body weight, smoking, and a family history of AMD, taken as part of an entire personalized treatment regimen, could positively impact the development of age-related macular degeneration.

scholarly journals Dietary Diversity in Cambodian Garment Workers: The Role of Free Lunch Provision

Nutrients ◽  
2018 ◽  
Vol 10 (8) ◽  
pp. 1010 ◽  
Author(s):  
Jan Makurat ◽  
Eleonore Kretz ◽  
Frank Wieringa ◽  
Chhoun Chamnan ◽  
Michael Krawinkel
Keyword(s):  
Vitamin A ◽  
Dietary Intake ◽  
Dietary Diversity ◽  
Controlled Trial ◽  
Leafy Vegetables ◽  
Food Groups ◽  
Green Leafy Vegetables ◽  
Garment Workers ◽  
Dark Green ◽  
Randomised Controlled

The objective of this paper is to compare food consumption by Cambodian garment workers with and without access to a free model lunch provision through a factory-based canteen. Data from an exploratory randomised controlled trial were analysed. In total, 223 female Cambodian garment workers were allocated to an intervention arm (six-month lunch provision) or a control arm. Dietary intake on workdays was assessed by qualitative 24-h recalls at baseline and twice at follow-ups during the period of lunch provision using the Food and Agricultural Organization (FAO) guideline on assessing women’s dietary diversity. In total, 158 participants provided complete data on the dietary intake over workdays at all interviews. Lunch provision resulted in a more frequent consumption of dark green leafy vegetables (DGLV), vitamin A-rich fruits, other fruits, and oils and fats during lunch breaks. In contrast, flesh meats, legumes, nuts and seeds, as well as sweets, were eaten at a lower frequency. Except for a higher consumption rate of vitamin A-rich fruits and a lower intake frequency of sweets, lunch provision had a less clear impact on total 24-h intake from different food groups and was not associated with a higher women’s dietary diversity score (WDDS). A more gap-oriented design of the lunch sets taking into account underutilised foods and the nutritional status of the workers is recommended.

scholarly journals Dietary Lutein, Zeaxanthin and Omega-3- Essential Fatty Acid Intake and Risk of Age-Related Macular Degeneration in a Selected Australian Population

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 111-111
Author(s):  
Kingsley Kalu ◽  
Angelica Ly ◽  
Charles McMonnies ◽  
Jayashree Arcot
Keyword(s):  
Fatty Acid ◽  
Family History ◽  
Macular Degeneration ◽  
South Asian ◽  
Middle Eastern ◽  
Age Related Macular Degeneration ◽  
Dietary Intakes ◽  
Omega 3 ◽  
Age Related ◽  
History Of

Abstract Objectives The aim of this study was to assess the dietary intakes of lutein, zeaxanthin (L + Z) and omega-3-essential fatty acid(EFA) among a selected population of Australian based adults and to examine the effect of specified risk factors for age-related macular degeneration(AMD) on those levels. Methods A cross-sectional study involving 70 adults aged 19–52 years was carried out. Demographic data were obtained using an online self-administered questionnaire while dietary intakes were estimated using USDA's 24 hours recall questionnaire, the Victorian Cancer Council(Australia) food frequency questionnaire and anthropometric characteristics were obtained using a body composition analyzer. Dietary intakes of lutein, zeaxanthin, omega-3-EFA and anthropometric indices against the risk of AMD were established using descriptive statistics and Spearman correlation. Results The mean age of the population was 29.9 ± 8.1years with 51% men and 49% women. Women had a higher intake of L + Z (1908.6 μg/day versus 1032.8 μg/day) and alpha-linolenic acid(ALA) compared to men(1.7 ± 1.1 g/day versus 1.6 ± 1.2 g/day). Men consumed more omega-3-EFA than women (433 ± 397.1 mg/day versus 365 ± 210.7 mg/day). L + Z levels were higher among people of Middle Eastern and South Asian origin (&gt;4000 μg/day) in the 19–25years age group. People of Middle Eastern, South East Asian and South Asian had the highest intake of omega-3-EFA(&gt;500 mg/day) at ages 19–25, 26–32 and 34–52years respectively. Women aged 34–52years with a family history of AMD had higher levels of L + Z(&gt;2500 μg/day) while women aged 26–32years with a family history of AMD had higher levels of ALA(&gt;3 g/day). Ethnicity and L + Z were correlated (P = −0.456, P &lt; 0.02). Higher levels of intake of L + Z (&gt;4000 μg/day) were seen in participants aged 34–52years with a 5–10years residence in Australia. Participants who had less than 5–10years of residency had higher levels of omega-3-EFA(&gt;500 mg/day) for ages 26–32years while those aged 34–52years who had less than 5years of residency had higher ALA(&gt;4 g/day). Conclusions Intake levels for L + Z vary significantly among participants. Culturally specific dietary habits could feasibly influence the levels of intake of L + Z. Intake levels of omega-3-EFA were met. This study provides detailed intake levels of L + Z and omega-3-EFA for the ‘at-risk’ AMD group. Funding Sources No funding source.

Sign in / Sign up

Export Citation Format

Share Document