scholarly journals MRI feature tracking strain in pulmonary hypertension: utility of combined left atrial volumetric and deformation assessment in distinguishing post- from pre-capillary physiology

2021 ◽  
Author(s):  
Kai'En Leong ◽  
Luke Howard ◽  
Francesco Lo Guidice ◽  
Holly Pavey ◽  
Rachel Davies ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Left Atrial ◽  
Feature Tracking ◽  
Cross Sectional Study ◽  
Right Atrial ◽  
Peak Strain ◽  
Sectional Study ◽  
Left Atrial Strain ◽  
Cross Sectional ◽  
Atrial Strain

Abstract AimsPulmonary hypertension (PH) is dichotomized into pre- and post-capillary physiology by invasive catheterization. Imaging, particularly strain assessment, may aid in classification and be helpful with ambiguous haemodynamics. We sought to define cardiac MRI (CMR) feature tracking biatrial peak reservoir and biventricular peak systolic strain in pre- and post-capillary PH and examine the performance of peak left atrial strain in distinguishing the 2 groups compared to TTE.Methods and resultsRetrospective cross-sectional study from 1 Jan 2015 to 31 Dec 2020; 48 patients (22 pre- and 26 post-capillary) were included with contemporaneous TTE, CMR and catheterization. Mean pulmonary artery pressures were higher in the pre-capillary cohort (55 + 14 mmHg vs 42 + 9 mmHg; p<0.001) as was pulmonary vascular resistance (median 11.7 WU vs 3.7 WU; p<0.001). Post-capillary patients had significantly larger left atria (60 + 22 ml/m2 vs 25 + 9 ml/m2; p<0.001). There was no difference in right atrial volumes between groups (60 + 21 ml/m2 vs 61 + 29 ml/m2; p=0.694), however peak RA strain was lower in post-capillary PH patients (8.9 + 5.5% vs 18.8 + 7.0%; p<0.001). In the post-capillary group, there was commensurately severe peak strain impairment in both atria (LA strain 9.0 + 5.8%, RA strain 8.9 + 5.5%). CMR LAVi and peak LA strain had a multivariate AUC of 0.98 (95% CI 0.89-1.00; p<0.001) for post-capillary PH diagnosis which was superior to TTE.ConclusionCMR volumetric and deformation assessment of the left atrium can highly accurately distinguish post- from pre-capillary PH.

Left atrial size and strain in elite athletes: A cross‐sectional study at the NBA Draft Combine

2020 ◽  
Vol 37 (7) ◽  
pp. 1030-1036
Author(s):  
Baljash Cheema ◽  
Menhel Kinno ◽  
David Gu ◽  
Juliet Ryan ◽  
Sumeet Mitter ◽  
...  
Keyword(s):  
Left Atrial ◽  
Elite Athletes ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Left Atrial Size ◽  
Cross Sectional ◽  
Atrial Size

scholarly journals RIGHT ATRIAL STRAIN IN A NORMAL ADULT AFRICAN POPULATION AND ITS CORRELATION WITH AGE

2021 ◽  
Author(s):  
Mushitu Nyange ◽  
Ruchika Meel
Keyword(s):  
Normal Values ◽  
Black Population ◽  
Cross Sectional Study ◽  
African Population ◽  
Right Atrial ◽  
Cross Sectional ◽  
Black African ◽  
The Mean ◽  
Atrial Strain ◽  
The Right

Background The right atrial longitudinal strain (RALS) has been shown to be a useful parameter to define right atrial (RA) subclinical dysfunction in several cardiovascular disorders prior to changes in traditional RA two dimensional and volumetric parameters. There is a scarcity of data regarding normal values for RALS in a normal African population. Objectives We sought to establish normal values for RALS and its correlation with age, in a Sub-Saharan black African population. Methods This was a retrospective cross-sectional study of 100 normal individuals (recruited as controls for another study) performed at Chris Hani Baragwanath Hospital (2017-2019). All echocardiographic measurements were done as per standard guidelines. RALS was measured using Philips QLAB 9 (Amsterdam, The Netherlands) speckle-tracking software. Results Median age was 37.5 years (IQR 26- 46, 60% females). The mean right atrial volume indexed to body surface area (RAVI) was 19.5 ± 5.7 mL/m and the mean RALS was 32.7 ± 10.5%. There was a trend towards decreasing RALS with age (r=-0.15, P=0.129) with no change in RAVI with age ( P=0.27). Males had a tendency towards higher RAVI and RALS measurements compared to females (20.8 ± 6.3 mL/m and 18.7 ± 5.2 mL/m , P=0.07: 34.6 ± 9.6% and 31.4 ± 10.9 %, P=0.141, respectively) . BMI was an independent predictor of RALS on multivariate analysis ( r= -0.43, P =0.003) Conclusion We have defined the normal reference values for RALS in a black population. RALS tended to decrease with age prior to change in RAVI and can serve as a marker of subclinical RA dysfunction . BMI was an important determinant of RALS.

scholarly journals Left Atrial Function by Speckle Tracking in Liver Cirrhosis. A Cross-sectional Study

2019 ◽  
Vol 87 (6) ◽  
pp. 453-456
Author(s):  
Zuilma Vásquez Ortiz ◽  
Verónica Rendón Bravo ◽  
Pablo Reyes Hernández ◽  
Jorge Osequera Moguel
Keyword(s):  
Liver Cirrhosis ◽  
Left Atrial ◽  
Speckle Tracking ◽  
Cross Sectional Study ◽  
Atrial Function ◽  
Left Atrial Function ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Left Atrial Strain as Evaluated by Two-Dimensional Speckle Tracking Predicts Left Atrial Appendage Dysfunction in Chinese Patients with Atrial Fibrillation

2020 ◽  
Vol 2020 ◽  
pp. 1-8 ◽  
Author(s):  
Yu Wang ◽  
Mingqi Li ◽  
Lishan Zhong ◽  
Siqi Ren ◽  
Hezhi Li ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Roc Curve ◽  
Left Atrial ◽  
Left Atrial Appendage ◽  
Atrial Appendage ◽  
Chinese Patients ◽  
Left Atrial Strain ◽  
Cross Sectional ◽  
Atrial Strain ◽  
Development And Validation

Left atrial appendage (LAA) dysfunction identified by transesophageal echocardiography (TEE) is a powerful predictor of stroke in patients with atrial fibrillation (AF). The aim of our study is to assess if there is a correlation between the left atrial (LA) functional parameter and LAA dysfunction in the AF patients. This cross-sectional study included a total of 249 Chinese AF patients who did not have cardiac valvular diseases and were undergoing cardiac ablation. TEE was performed in all the patients who were categorized into two groups according to their left atrial appendage (LAA) function. A total of 120 of the 249 AF patients had LAA dysfunction. Univariate and multivariate logistic regression was conducted to assess the independent factors that correlated with the LAA dysfunction. Different predictive models for the LAA dysfunction were compared with the receiver operating characteristic (ROC) curve. The final ROC curve on the development and validation datasets was drawn based on the calculation of each area under the curves (AUC). Univariate and multivariate analysis showed that the peak left atrial strain (PLAS) was the most significant factor that correlated with the LAA dysfunction. PLAS did not show inferiority amongst all the models and revealed strong discrimination ability on both the development and validation datasets with AUC 0.818 and 0.817. Our study showed that a decrease in PLAS is independently associated with LAA dysfunction in the AF patients.

Predictive effect of serum uric acid and blood pressure on the left atrial size in Chinese south population

2020 ◽  
Author(s):  
danhong Fang ◽  
Gaojun Wu ◽  
Qinfen Chen ◽  
Jiansheng Wu ◽  
Shengjie Wu ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
Left Atrial ◽  
Blood Pressure Level ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Atrial Size ◽  
Predictive Effect

Abstract Background: Serum uric acid (SUA) is strongly associated with hypertension and is associated with a variety of cardiovascular diseases. In this study we aimed to investigate the predictive effect of SUA and blood pressure on the left atrial (LA) size in Chinese south population. Methods: In this cross-sectional study, we investigated the association between SUA and LA diameter and studied the risk of LA enlargement among subjects with and without hyperuricemia (HU) in different grades of blood pressure in a single-center database (n=5392). Results: The LA diameter was significantly correlated with SUA(r=0.31, P<0.001). The incidence of LA enlargement was significantly greater in subjects with HU than in those without HU [25.7% vs. 14.2%, P<0.001; odds ratio (OR) = 2.09, 95% confidence interval (CI) = (1.78,2.45)], especially in women [21.8% vs. 7.4%, P<0.001; OR=3.50, 95%CI= (2.35, 5.22)]. In subjects with hypertension (≥140/90 mmHg) and HU, the risk of LA enlargement was 7.90 times higher than those with ideal blood pressure (< 120/80 mmHg) and normal SUA [33.1% vs. 5.9%; P<0.001, OR=7.90, 95% CI= (5.87,10.63)]. At the same blood pressure level, the risk of LA enlargement in HU subjects was higher than that in normal SUA (P<0.01). After adjustment for blood pressure, the effect of HU on LA size still exists[public OR=1.82, 95% CI=(1.54,2.14), P<0.001]. Conclusions: HU is an independent risk factor of LA enlargement in Chinese south population. SUA and blood pressure play a synergistic role in predicting the increase of LA diameter. Keywords: Uric acid, Hyperuricemia, Blood pressure, Left atrium

Sign in / Sign up

Export Citation Format

Share Document