Equus roundworms (Parascaris spp.) are undergoing divergence due to natural and anthropogenic factors

2021 ◽  
Author(s):  
Lei Han ◽  
Tianming Lan ◽  
Yaxian Lu ◽  
Mengchao Zhou ◽  
Haimeng Li ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Environmental Factors ◽  
Continuous Monitoring ◽  
Anthropogenic Factors ◽  
Molecular Evidence ◽  
Strong Positive Selection ◽  
History Of ◽  
Genetic Level ◽  
Work Supports ◽  
Natural And Anthropogenic Factors

Abstract The evolution of parasites is often directly affected by the host's environment or behavior. Studies on the evolution of the same parasites in different hosts are extremely attractive and highly relevant to our understanding of divergence and speciation. Here we presented the first molecular evidence of divergence of Equus roundworms in different hosts (horses, zebras and donkeys). At the genetic level, Equus roundworms were mainly separated into two clades (Horse-derived and Zebra & Donkey-derived). This divergence began at 600–1500 years ago, which interestingly coincided with the domestication history of horses. We found that most of the key enzymes related to glycolysis were under strong positive selection in zebra & donkey-derived roundworms, indicating that the evolution of the metabolic level was one of the main reasons for the divergence. In addition, we conducted a selective scan of resistance-related genes and found that the three populations were under different degrees of selection. This prompted us to pay attention to the possible impact of drugs on divergence, not just the drug resistance. This work supports that divergence or speciation is a continuous and dynamic process, and continuous monitoring of environmental factors is conducive to further understanding the adaptive evolution of roundworms.

Environmental problems in the Alinjachai basin as a result of natural and anthropogenic impacts and ways to overcome them

2021 ◽  
Vol 07 (02) ◽  
pp. 25-28
Author(s):  
Nailə Zahid qızı Əliyeva ◽  
Keyword(s):  
Climate Change ◽  
Agricultural Development ◽  
Anthropogenic Impacts ◽  
Animal Husbandry ◽  
Environmental Problems ◽  
Anthropogenic Factors ◽  
Drying Up ◽  
History Of ◽  
Ancient Times ◽  
Natural And Anthropogenic Factors

The article provides information on the environmental problems of the Alinjachai basin under the influence of natural and anthropogenic factors. It is noted that the Alinjachai basin is one of the largest river basins in the Nakhchivan Autonomous Republic. The history of human settlement here dates back to ancient times, and at the same time it is one of the fastest growing areas of agriculture and animal husbandry. Provides information about the morphometry of the river, gives detailed information about the climatic features of the area, climatic types, distribution of precipitation by seasons and months, types of landscape. Ancient settlements in this area, agricultural development, population growth, climate change have led to an increase in anthropogenic impact on nature, and, thus, environmental problems have arisen. In particular, climate change has led to a decrease in biomass, accelerated erosion and desertification. In the past, the Alinjachai River provided the population's water needs throughout the year, but today the Alinjachai River is one of the drying up rivers.

scholarly journals Morphological variability of Bembidion minimum (Coleoptera, Carabidae) populations under the influence of natural and anthropogenic factors

2019 ◽  
Vol 27 (3) ◽  
pp. 250-269
Author(s):  
V. O. Komlyk ◽  
V. V. Brygadyrenko
Keyword(s):  
Environmental Factors ◽  
Body Length ◽  
Soil Acidity ◽  
Plant Cover ◽  
Morphological Variability ◽  
The Body ◽  
Head Length ◽  
Anthropogenic Factors ◽  
Angular Characteristic ◽  
Natural And Anthropogenic Factors

Morphological variability is the result of interaction between genetic diversity of the population and environmental selection. Despite the large number of studies of morphological variability of ground beetles, there is very little research dedicated to influence of environmental factors on it. This article discusses the influence of natural and anthropogenic factors on the variability of Bembidion minimum (Fabricius, 1792). B. minimum is a West Palearctic species which is distributed in North Africa, Europe, Western Asia. It is a macropterous species that lives in humid biotopes along the shores of seas, rivers and standing water bodies. 410 specimens were collected from 12 ecosystems differing by plant cover, degree of litter development, mechanical composition of the soil, mineralization and acidity of soil solution, type and intensity of anthropogenic impact. 13 linear characteristics, one angular characteristic, density of elytra puncturing and contrast of spots on the beetles’ elytra were measured. Additionally 6 morphometric indices were calculated. More than a third of the variability of imagoes in the studied populations was found to be determined by the general body size. Sexual dimorphism was observed on all linear parameters and most morphometric indices. Females do not differ from males in the back angles of the prothorax. Natural and anthropogenic factors to a greater or lesser degree were shown to affect the morphological variability of B. minimum: soil acidity and mineralization have the greatest impact. The soil acidity causes significant variability of most linear parameters; mineralization – body length, head length, prothorax length and width, elytra width. Plant cover and mechanical composition of the soil have a slight impact on imago morphology. The type and structure of vegetation significantly affect head width, prothorax length and width, and the mechanical composition of the soil – body length and head length. Degree of litter development does not cause significant changes in the linear dimensions of beetles. With thickening of the litter the posterior spots on the elytra become brighter, they have sharper contours, and density of elytra puncturing also changes. The mean value of the back angles is affected by the herb layer of meadow vegetation, soil mineralization and acidity. The variability of morphometric indexes under the influence of natural factors was found to be lower than variability of linear characteristics. The recreational load and cattle grazing cause similar changes in linear measurements and morphometric indexes of B. minimum. With escalation of these factors, the body length, length and width of elytra of both females and males decrease. Assessing the natural morphological variability of populations in ecosystems whose environmental factors are within extreme and sub-extreme values for a given population is a promising direction of research in modern ecology.

scholarly journals ASPECTS OF THE RESTORATION OF THE CAVE TEMPLES AND MONASTERIES

2021 ◽  
Vol 2 (3) ◽  
pp. 62-69
Author(s):  
Polina Vovzhenyak ◽  
M. Per'kova ◽  
L. Kolesnikova ◽  
S. Semencov
Keyword(s):  
Urban Planning ◽  
Research Problem ◽  
Object Identification ◽  
Operating Conditions ◽  
Anthropogenic Factors ◽  
Resource Potential ◽  
History Of ◽  
Underground Facility ◽  
Further Development ◽  
Natural And Anthropogenic Factors

The research problem lies in the urgent need to preserve the historical, cultural, and architectural and urban planning heritage of cave monasteries due to the risk of their loss. Natural and anthropogenic factors of the destruction of cave temples and monasteries were formulated. Ways to preserve cave temples and monasteries were considered. Principles for the development of design solutions for the revitalization of the adjacent territory and the cave monastery were proposed, such as functional, urban planning, infrastructural, the principle of the identity of the environment. The following algorithm for revitalizing cave monasteries was proposed: a study of the place and history of the emergence of the cave monastery; a study of the resource potential of the object; identification of problems of further development of the territory and underground facility; development of a conceptual proposal for adapting the facility to modern operating conditions.

scholarly journals Forest fire hazard assessment by clustering and using neural networks under unstability and uncertainty

2020 ◽  
Vol 2020 (2) ◽  
pp. 56-69
Author(s):  
Tatiana Sergeevna Stankevich
Keyword(s):  
Risk Assessment ◽  
Environmental Factors ◽  
Forest Fire ◽  
Forest Fires ◽  
Minimum Distance ◽  
Fire Risk ◽  
Anthropogenic Factors ◽  
Fire Weather ◽  
Forest Fire Risk ◽  
Natural And Anthropogenic Factors

The paper focuses on the data on forest fires and identification of key natural and anthropogenic factors that are crucial for forest management, especially, for developing and implementing the fire safety measures. In recent decades, there have been observed the increased environmental, social and economic losses from the forest fires on a global scale, which has required stepped-up fire-fighting surveillance, especially in the preventive forest fire risk assessment. In all the variety of modern approaches aimed at assessing the fire hazards to the forests and taking into account the effecting environmental factors, most of them are based on simplified calculations and do not take into account different factors, mainly anthropological ones. The purpose of the study is to assess the forest fire risk depending on the environmental factors by using cluster analysis in conditions of instability and uncertainty. It could help applying the integrated approach to forest fire risk assessing in order to take into account both natural and anthropogenic factors in difficult conditions. To assess the forest fire risk, there were used the data obtained by MODIS spectroradiometer from January 1, 2014 to November 24, 2019: latitude; longitude; acquisition time and date. The following parameters were used as additional: Fire Weather Index; minimum distance to an inhabited locality; minimum distance to the road (highway or railway); minimum distance to the water area; holiday / day off; potential value. According to the results of the spatial distribution of forest fires and taking into account the data on the environmental factors there have been formed three clusters; there has been revealed a key relationship between the probability of a forest fire and proximity to the inhabited locality. There has been submitted the index of forest fire risk assessment (the Fire Weather and Human Index (FWHI)) based on the natural and anthropogenic impacts. Identification of social and biophysical aspects of the community exposure to fires and the adaptation of the existing fire prevention strategy will improve the forest fire safety system.

Gene mutation and drug resistance of M. tuberculosis in the patients followed up in the city of Moscow

2020 ◽  
Vol 97 (12) ◽  
pp. 34-44
Author(s):  
M. A. Krasnova ◽  
E. M. Belilovsky ◽  
S. E. Borisov ◽  
A. A. Khakhalina ◽  
Yu. D. Mikhaylova ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Statistical Significance ◽  
Molecular Genetic ◽  
Previous Treatment ◽  
Repeated Treatment ◽  
Phenotypic Resistance ◽  
Therapy Regimen ◽  
Treatment History ◽  
History Of ◽  
Relationship Of

The article describes a retrospective study of the results of microbiological and molecular genetic tests of 685 M. tuberculosis cultures isolated from 685 adult tuberculosis patients registered for dispensary follow-up in Moscow in 2014.The following was identified during the study: phenotypic drug resistance (FDR) of MTB to rifampicin, isoniazid, fluoroquinolones, kanamycin, amikacin, and capreomycin in groups of patients with different treatment history; the frequency of FDR to the above anti-tuberculosis drugs in strains with mutations being drug resistance markers; the frequency of various mutations in case of FDR of mycobacteria in the patients from different groups; the relationship of FDR or the presence of a particular mutation with various characteristics of the patients and their treatment history.The history of previous treatment was determined as statistical significance to provide the greatest influence on the spread of drug resistant MTB: patients undergoing repeated treatment had FDR more often and also a much more pronounced variety of mutations being markers of FDR to certain anti-tuberculosis drugs.The results of the study showed that the detection of genetic mutations in MBT associated with FDR was a reliable tool for predicting phenotypic resistance and should be used as the main method for selecting anti-tuberculosis drugs when compiling the etiotropic therapy regimen.

scholarly journals Correlation of Circular RNA hsa_circ_0001946, hsa_circ_0125589, and Environmental Factors With Hypertension

2020 ◽  
Vol 33 (11) ◽  
pp. 1047-1047
Author(s):  
Wan-yue Liu ◽  
Yi Sun ◽  
Shu-na Huang ◽  
Yu-zhen Lin ◽  
Hong-yan Guo ◽  
...  
Keyword(s):  
Environmental Factors ◽  
Peripheral Blood ◽  
Circular Rna ◽  
Peripheral Blood Lymphocytes ◽  
Normal Weight ◽  
Circular Rnas ◽  
Blood Leukocytes ◽  
Crossover Analysis ◽  
History Of ◽  
The Relationship

Abstract Background To investigate the main environmental factors of hypertension and the relationship between hypertension and circular RNAs in peripheral blood lymphocytes. Methods This was a case–control study. A total of 681 hypertension patients and 485 subjects without hypertension were recruited between April 2017 and October 2018. All participations completed the questionnaire investigation, physical examination, and laboratory detection. Quantitative real-time polymerase chain reaction was used to analyze circRNAs (hsa_circ_0001946 and hsa_circ_0125589) in peripheral blood leukocytes in 84 hypertensives and 84 controls. Multivariate logistic regression and crossover analysis were used to analyze the interaction and association between environmental factors and circRNAs in hypertension. Results After adjusted by gender, age and marital status, overweight/obesity (odds ratio (OR) = 1.66, 95% confidence interval (CI) 1.24–2.22), abdominal obesity (OR = 2.17, 95% CI 1.54–3.04), anxiety (OR = 2.15, 95% CI 1.41–3.28), family history of hypertension (OR = 4.26, 95% CI 3.18–5.70), and higher levels of hsa_circ_0001946 (OR = 4.13, 95% CI 1.85–9.21) were risk factors for hypertension, while levels of hsa_circ_0125589 were not associated with hypertension. Crossover analysis showed that the risk of hypertension was 13.12 times higher (95% CI 3.89–44.23) in overweight subjects with high hsa_circ_0001946 levels compared with normal weight subjects with low hsa_circ_0001946 levels. Further, the risk of hypertension was 17.78 times higher (95% CI 1.88–168.61) in subjects with anxiety and high hsa_circ_0001946 levels. Conclusions Hypertension is the result of both environmental factors and genetic factors. Higher hsa_circ_0001946 levels, overweight and anxiety may increase the risk of hypertension, while hsa_circ_0125589 levels are not related to hypertension.

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