scholarly journals Effect of Age on Primary Balloon Dacryocystoplasty and Probing Success in Congenital Nasolacrimal Duct Obstruction

2021 ◽  
Author(s):  
Volkan Dericioğlu ◽  
Mehmet Orkun Sevik ◽  
Sena Sümmen Saçu ◽  
Muhsin Eraslan ◽  
Eren Cerman
Keyword(s):  
Success Rate ◽  
Age Groups ◽  
Nasolacrimal Duct ◽  
Success Rates ◽  
Congenital Nasolacrimal Duct Obstruction ◽  
Duct Obstruction ◽  
Group 3 ◽  
Group 2 ◽  
Effect Of Age ◽  
Group 1

Abstract Purpose: To compare the success rates of balloon dacryocystoplasty (BDP) and probing as a primary procedure in congenital nasolacrimal duct obstruction (CNLDO) and investigate the effect of age on both procedures.Methods: A total of 135 patients (171 eyes) with simple or incomplete complex CNLDO were included in this retrospective study; complete complex CNLDO cases were excluded. The success rates for primary BDP (118 eyes) and for probing (53 eyes) were compared as overall and among the age groups; Group 1 (12–24 months old), Group 2 (25–36 months old), and Group 3 (> 36 months old).Results: Mean age of the patients was 41.5±27.2 months for primary BDP, and 21.8±10.8 months for probing (p<0.001). Overall success rates for primary BDP and probing were 81.1% (43/53) and 76.3% (90/118), respectively (p=0.481). Success rates for BDP and probing among age groups were, 93.8% and 85.3% in Group 1 (p=0.306), 93.3% and 50.0% in Group 2 (p=0.012), and 63.6% and 27.3% in Group 3 (p=0.052), respectively. Cox regression analysis showed that the median ages were 18 months for probing and 36 months for primary BDP. Poisson regression model showed that, for every one-month increase in patients’ age, the success rate of probing decreased by 9.7%.Conclusion: Probing success decreased to a point where different treatment options such as primary BDP can be discussed with the patient’s parents after 18 months of age. The success of BDP decreased after 36 months, while it maintained a high success rate between 24-36 months as primary treatment.

scholarly journals Probing without Irrigation in Children with Congenital Nasolacrimal Duct Obstruction

2013 ◽  
Vol 36 (3) ◽  
pp. 158 ◽  
Author(s):  
Gloria Isaza ◽  
Sourabh Arora
Keyword(s):  
Success Rate ◽  
Nasolacrimal Duct ◽  
Nasolacrimal Duct Obstruction ◽  
Purulent Discharge ◽  
Complete Disappearance ◽  
Congenital Nasolacrimal Duct Obstruction ◽  
Duct Obstruction ◽  
Significant Difference ◽  
Group 2 ◽  
Group 1

Purpose: The purpose of this study was to evaluate the results of probing, without fluorescein irrigation, as a primary treatment for epiphora and/or mucous discharge, secondary to congenital nasolacrimal duct obstruction (CNLDO) Methods: The medical records of nine-two children (127 eyes) with CNLDO who underwent a single probing without the use of fluorescein irrigation between January 2006 and December 2011 were reviewed retrospectively. Inclusion criteria were no prior nasolacrimal surgical procedure, history of epiphora and/or discharge since birth or shortly after birth in one or both eyes and at least one of the following clinical signs: epiphora, muco-purulent discharge and increased tear meniscus height. Children were investigated in two sub-groups based on age at time of probing; group 1 (51 eyes/40 children) included children who underwent probing at age ≤ 2 years and group 2 (76 eyes/52 children) included children who underwent probing at age > 2years. The primary outcome was the complete disappearance of symptoms and signs in the affected eye(s), assessed at 3 months after surgery. Results: The success rate for the overall sample was 83.5 % (106/127 eyes), in group 1 was 90.2% (46/51) and in group 2 was 78.9% (60/76). There was no significant difference in success rate between groups (p=0.094). Gender (p=0.292), affected eye (p=0.647) and bilateral cases (p=0.739) were not associated with successful elimination of symptoms. Conclusion: Probing without fluorescein irrigation for CNLDO beyond 1 year of age is highly successful and comparable to the published efficacy rates of the traditional probing with fluorescein irrigation.

scholarly journals Outcomes and comparison of nasolacrimal probing for patients older than 12 months

2020 ◽  
Vol 12 ◽  
pp. 251584142092713
Author(s):  
Kürsad Ramazan Zor ◽  
Erkut Küçük ◽  
Zeynep Yılmaz Öztorun
Keyword(s):  
Success Rate ◽  
Nasolacrimal Duct ◽  
Older Age ◽  
Nasolacrimal Duct Obstruction ◽  
Age Group ◽  
Success Rates ◽  
Congenital Nasolacrimal Duct Obstruction ◽  
Duct Obstruction ◽  
Initial Surgery ◽  
First Choice

Objective: In this study, we report the results of probing done in our clinic. We also want investigate role of late probing on outcome, especially in children older than 24 and 48 months. Methods: We retrospectively evaluated records of patients who underwent probing under general anaesthesia due to congenital nasolacrimal duct obstruction between 2013 and 2017 in Nigde Ömer Halisdemir University Faculty of Medicine in Nigde, Turkey. Success rates of probing for different age groups were compared. Results: 143 eyes of 123 patients were included in the study. Overall success rate was 93.7% (134 eyes out of 143). We found the success rate as 95.5 in 12–18 months age group, 93.3% in 18–24 months age group, 93.8% in the 24–48 months age group, 86.6% in the 48 months and older age group. Overall success rate in 24 months and older age group was 91.5%. The second operation was performed on seven of the nine patients where the initial surgery failed, and successful results were achieved in six patients. Success rate was 100% after the second surgery in patients older than 48 months. Conclusion: The success rate of probing is high in patients with congenital nasolacrimal duct obstruction from 12 to 84 months. In patients with congenital nasolacrimal duct obstruction who are older than 48 months probing is effective and should be first-choice in this age group in management of congenital nasolacrimal duct obstruction. Probing may be used even in older patients who had previous unsuccessful probing.

Success rates of endoscopic-assisted probing for congenital nasolacrimal duct obstruction in children

2013 ◽  
Vol 127 (8) ◽  
pp. 794-798 ◽  
Author(s):  
S Theodoropoulou ◽  
M S M Sutherland ◽  
K Haddow ◽  
A Blaikie
Keyword(s):  
Success Rate ◽  
Nasolacrimal Duct ◽  
Nasolacrimal Duct Obstruction ◽  
Developmental Abnormality ◽  
Success Rates ◽  
Congenital Nasolacrimal Duct Obstruction ◽  
Duct Obstruction ◽  
Fluorescein Dye ◽  
Age Range ◽  
Test Result

AbstractObjective:To determine the success rate of initial probing in children with congenital nasolacrimal duct obstruction at different ages, using nasal endoscopy.Methods:Fifty eyes of 38 consecutive children with congenital nasolacrimal duct obstruction underwent endoscopic nasolacrimal duct probing under general anaesthesia. Patients were followed up for at least three months. Probing success was defined as complete remission of symptoms and a normal fluorescein dye disappearance test result.Results:The age range of patients was 17–109 months. The success rates of probing were: 100 per cent (29 out of 29) for cases of stenosis at the lower nasolacrimal duct, 100 per cent (7 out of 7) for functional epiphora cases and 92.86 per cent (13 out of 14) for nasolacrimal atresia cases. Overall, there was only one child for whom the probing treatment for nasolacrimal duct obstruction was not successful; this child had Down's syndrome and a more complex developmental abnormality of the nasolacrimal duct. Age and site of obstruction were not found to significantly affect the outcome of probing.Conclusion:Probing of the nasolacrimal system using an endoscopic approach allows direct visualisation of the nasolacrimal duct. This can facilitate diagnosis of the anomaly and significantly increase the procedure success rate.

scholarly journals Outcomes of external dacryocystorhinostomy and endoscopic endonasal dacryocystorhinostomy in the management of nasolacrimal duct obstruction

2015 ◽  
Vol 7 (1) ◽  
pp. 39-46 ◽  
Author(s):  
S Duwal ◽  
R Saiju
Keyword(s):  
Success Rate ◽  
Nasolacrimal Duct ◽  
Nasolacrimal Duct Obstruction ◽  
Endoscopic Endonasal ◽  
Duct Obstruction ◽  
Dence Interval ◽  
External Dacryocystorhinostomy ◽  
Group 2 ◽  
External Dcr ◽  
Group 1

Introduction: Dacryocystorhinostomy (DCR) is the treatment of choice for nasolacrimal duct obstruction. Although external DCR is regarded as the gold standard, endoscopic DCR is evolving as an equally-effective alternative. Objectives To compare the success rate of treating nasolacrimal duct obstruction by endoscopic endonasal method compared to the conventional DCR surgery.Materials and methods This prospective, comparative, non-randomised study was conducted in 2009 - 2010. Thirty consecutive patients undergoing endoscopic endonasal DCR (Group 1) and 30 consecutive patients undergoing external DCR (Group 2) between July 2009 and September 2010 at the oculoplasty unit of the Tilganga institute of ophthalmology were included in this study. A patent lacrimal passage on syringing and symptomatic improvement at six months after surgery was de¿ned as a successful outcome. The intraoperative and postoperative complications were also compared. Results Our study included 31 eyes of 30 patients in Group 1 and 34 eyes of 30 patients in Group 2. The success rate for endoscopic endonasal dacryocystorhinostomy was 90.3 % (95 % con¿dence interval 80 - 100) and external dacryocystorhinostomy was 94.1 % (95 % con¿dence interval 80 - 100). The difference of surgical success among the two methods was not statistically significant (p = 0.7). The rate of intra-operative and post-operative complications was similar in the two methods (p = 0.5). Conclusion: The short term outcomes and complication rates of endoscopic endonasal dacryocystorhinostomy and external dacryocystorhinostomy were similar.

scholarly journals Success rates of probing for congenital nasolacrimal duct obstruction at various ages

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Marta Świerczyńska ◽  
Ewelina Tobiczyk ◽  
Piotr Rodak ◽  
Dorota Barchanowska ◽  
Erita Filipek
Keyword(s):  
Age Groups ◽  
Significant Risk ◽  
Nasolacrimal Duct ◽  
Nasolacrimal Duct Obstruction ◽  
Optimal Timing ◽  
Success Rates ◽  
Chi Square ◽  
Congenital Nasolacrimal Duct Obstruction ◽  
Duct Obstruction ◽  
Chi Square Test

Abstract Background Although nasolacrimal duct probing is the standard treatment for congenital nasolacrimal duct obstruction (CNLDO) among children, the optimal timing of this procedure has been a topic of debate. The aim of the study was to analyze the clinical efficacy of nasolacrimal duct probing among patients with CNLDO symptoms at various ages. Methods An 8-year retrospective study involved 2434 patients (3009 eyes), who underwent nasolacrimal duct probing conducted under topical anesthesia in the operating theatre. The study group consisted of 1148 girls (47.2%) and 1286 boys (52.8%) from 2 weeks to 41 months (average age was 8 ± 5.6 months). The participants were divided into nine age groups: 0–2 months, 3–6 months, 7–9 months, 10–12 months, 13–15 months, 16–18 months, 19–21 months, 22–24 months and over 24 months. Results Bilateral obstruction was present among 575 (23.6%) children and was associated with a higher percentage of unsuccessful procedures compared to patients with unilateral obstruction (16.9% vs 10.2%, p < 0.001 Chi-square test). The success rate of the initial probing was 87.2% for all children and it was shown that it decreased with age. In the above age groups, it was 87.9%; 91.4%; 89.6%; 86%; 76.3%; 71.3%; 70.3%; 70.2%; 65.4%, respectively. Conclusions Probing is a safe and effective procedure. However, age at the time of the initial intervention and bilateral surgery constitute significant risk factors for failed probing. Probing between 7 and 9 months appears to be reasonable treatment strategy for children without recurrent infections. Early surgical intervention may be considered for patients with additional signs.

The effect of age on the female reproductive tract of the hopping-mouse Notomys alexis

1976 ◽  
Vol 24 (4) ◽  
pp. 533 ◽  
Author(s):  
S Telfer ◽  
WG Breed
Keyword(s):  
Reproductive Tract ◽  
Age Groups ◽  
Female Reproductive Tract ◽  
Corpora Lutea ◽  
Female Reproductive System ◽  
Group 3 ◽  
Group 2 ◽  
Secondary Lysosomes ◽  
Effect Of Age ◽  
Group 1

The effect of age on the female reproductive system of N. alexis was investigated in the following age groups: (1) 2.5-6 months; (2) 1-2 years; (3) >2 years old. Oestrous cycle length was slightly reduced in group 2 females relative to group 1, but most group 3 females showed either constant dioestrus or constant oestrus. Body, ovarian and uterine weights all tended to increase with age, and Graafian follicles and corpora lutea were present in females in all groups although the latter were significantly fewer in group 3. Cytology of uterine epithelial cells of females in dioestrus indicated that numbers of microvilli in old animals were somewhat variable but generally decreased, some cells appearing almost devoid of them, whereas numbers of secondary lysosomes and multi-vesicular bodies tended to increase. The effect of these differences on possible infertility have, however, yet to be proved.

scholarly journals Efficacy and Safety of Inhalation Sedation during Office Probing for Congenital Nasolacrimal Duct Obstruction

2021 ◽  
Vol 10 (8) ◽  
pp. 1800
Author(s):  
Chunghyun Lee ◽  
Su-Min Jeong ◽  
Gye Jung Kim ◽  
Eun-Young Joo ◽  
Myung Hee Song ◽  
...  
Keyword(s):  
Success Rate ◽  
Physical Restraint ◽  
Nasolacrimal Duct ◽  
Nasolacrimal Duct Obstruction ◽  
Multivariable Logistic Regression Analysis ◽  
Success Rates ◽  
Congenital Nasolacrimal Duct Obstruction ◽  
Duct Obstruction ◽  
Inhalation Sedation ◽  
Sedation Group

We compared the effectiveness of inhaled sevoflurane versus physical restraint during probing in children with congenital nasolacrimal duct obstruction (CNLDO). We performed a retrospective review of children with CNLDO who underwent office probing procedures by a single surgeon under sedation or restraint. Patients’ characteristics at the time of probing, including age, sex, laterality, previous non-surgical treatment, presence of dacryocystitis, outcomes of probing, and complications were compared between the sedation and restraint groups. A multivariable logistic regression analysis was performed to investigate the prognostic factors associated with the success of probing. A subgroup analysis by 12 months of age was also conducted. The overall success rate was 88.6% in 202 eyes of 180 consecutive children (mean age, 15.1 ± 7.7 months). The sedation group had a marginally higher success rates than the restraint group (93.8% vs. 85.1%, p = 0.056). The success rate was not significantly different between the two groups in children aged <12 months (90.9% vs. 93.1%, p = 0.739), but it was significantly higher in the sedation group (94.7% vs. 77.8%. p = 0.006) in children aged ≥12 months. Inhalation sedation was the most potent factor associated with success (adjusted odds ratio = 5.56, 95% confidence interval = 1.33–23.13, p = 0.018) in children aged ≥12 months. There were no surgical or sedation-related complications intra- and postoperatively. Inhaled sevoflurane sedation resulted in more successful, controlled, painless probing, particularly in children aged ≥12 months. It represents a safe, efficient alternative to general anesthesia.

scholarly journals Analysis of Age as a Possible Prognostic Factor for Transcanalicular Multidiode Laser Dacryocystorhinostomy

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Emre Ayintap ◽  
Ibrahim Bulent Buttanri ◽  
Fariz Sadıgov ◽  
Didem Serin ◽  
Mustafa Ozsutcu ◽  
...  
Keyword(s):  
Success Rate ◽  
Nasolacrimal Duct ◽  
Skin Incision ◽  
Old Patients ◽  
Surgical Success ◽  
Group 4 ◽  
Group 3 ◽  
Group 5 ◽  
Group 2 ◽  
Group 1

Purpose. To assess the prognostic value of age on the outcome of transcanalicular multidiode laser dacryocystorhinostomy (TCL-DCR) in patients with acquired nasolacrimal duct obstruction (NLDO).Methods. The medical records of TCL-DCR performed between March 2009 and September 2013 were reviewed retrospectively. Inclusion criteria include over 20 years of age, similar mean follow-up period, and similar mean duration of stenting. The main outcome is surgical success. The effect of age on success rate is also evaluated.Results. The anatomical success was 52% in Group 1 (20–30 years), 56% in Group 2 (31–40 years), 64% in Group 3 (41–50 years), 76% in Group 4 (51–60 years), and 88% in Group 5 (over 60 years). The statistical difference among Group 1 and Group 5, in terms of surgical success rate, was found to be significant (P=0.009). Additionally, the 20–30-year-old patients had a failure rate 6.76 times higher than that of the over-60-year-old patients (P=0.009; 95% CI, 1.605–28.542).Conclusion. TCL-DCR is a surgical treatment option for NLDO for which a skin incision can be avoided. The success rate of TCL-DCR for younger population is lower when compared with elderly population.

scholarly journals Comparison of Transcanalicular Multidiode Laser Dacryocystorhinostomy with and without Silicon Tube Intubation

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Yildiray Yildirim ◽  
Taner Kar ◽  
Tuncay Topal ◽  
Enver Cesmeci ◽  
Abdullah Kaya ◽  
...  
Keyword(s):  
Diode Laser ◽  
Nasolacrimal Duct ◽  
Nasolacrimal Duct Obstruction ◽  
Success Rates ◽  
Duct Obstruction ◽  
Significant Difference ◽  
Silicon Tube ◽  
Silicone Tube Intubation ◽  
Group 2 ◽  
Group 1

Aim. To compare the surgical outcomes of surgery with and without bicanalicular silicon tube intubation for the treatment of patients who have primary uncomplicated nasolacrimal duct obstruction.Methods. This retrospective study is comprised of 113 patients with uncomplicated primary nasolacrimal duct obstruction. There were 2 groups in the study: Group 1 (n=58) patients underwent transcanalicular diode laser dacryocystorhinostomy surgery with bicanalicular silicon tube intubation and Group 2 (n=55) patients underwent transcanalicular diode laser dacryocystorhinostomy surgery without bicanalicular silicon tube intubation. The follow-up period was18.42±2.8months for Group 1 and18.8±2.1months for Group 2.Results. Success was defined by irrigation of the lacrimal system without regurgitation and by the absence of epiphora. Success rates were 84.4% for Group 1 and 63.6% for Group 2 (P=0.011). Statistically a significant difference was found between the two groups.Conclusion. The results of the study showed that transcanalicular diode laser dacryocystorhinostomy surgery with bicanalicular silicon tube intubation was more successful than the other method of surgery. Consequently, the application of silicone tube intubation in transcanalicular diode laser dacryocystorhinostomy surgery is recommended.

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