scholarly journals ASD Toddlers Exhibit Impaired Development of Neural Systems That Respond to and Guide Mother-Child Interactions

2020 ◽  
Author(s):  
Yaqiong Xiao ◽  
Teresa Wen ◽  
Lauren Kupis ◽  
Lisa Eyler ◽  
Disha Goel ◽  
...  
Keyword(s):  
Eye Tracking ◽  
Language Learning ◽  
Clinical Data ◽  
Neural Systems ◽  
Neural Responses ◽  
Data Types ◽  
Language Abilities ◽  
Emotion Development ◽  
Behavioral Preference ◽  
Human Specific

Abstract Motherese is an experience-expectant, human-specific and innate form of parent speech that enhances social and language learning, and affect and emotion development in infants. An early sign of ASD is the child’s lack of responding to motherese and reduced social mother-child interactions. To learn why, we devised a novel experiment quantifying (a) neural responses to motherese and other emotion speech with sleep fMRI and (b) active behavioral preference for motherese with eye tracking in ASD and TD toddlers. We combined the power of diverse neural and clinical data types using Similarity Network Fusion to reveal four neural-clinical clusters. The ASD cluster with the weakest neural responses to motherese and the poorest social and language abilities had the lowest eye tracking attention to motherese, while the TD cluster with the strongest neural response to motherese showed the opposite effects. We conclude that the ASD child’s impairment in engaging in social mother-child interactions is due to impaired development of innate neural systems that normally respond to and guide behavior that maintains mother-child interactions.

Language and Aging

2019 ◽  
pp. 294-316
Author(s):  
Jonathan E. Peelle
Keyword(s):  
Language Processing ◽  
Brain Function ◽  
Neural Systems ◽  
Language Abilities ◽  
Physiological Mechanisms ◽  
Cognitive Changes ◽  
Older Adulthood ◽  
Neural Organization ◽  
Age Related ◽  
High Level

Language processing in older adulthood is a model of balance between preservation and decline. Despite widespread changes to physiological mechanisms supporting perception and cognition, older adults’ language abilities are frequently well preserved. At the same time, the neural systems engaged to achieve this high level of success change, and individual differences in neural organization appear to differentiate between more and less successful performers. This chapter reviews anatomical and cognitive changes that occur in aging and popular frameworks for age-related changes in brain function, followed by an examination of how these principles play out in the context of language comprehension and production.

Perception of Formant Transition Cues to Place of Articulation in Children With Language Impairments

1993 ◽  
Vol 36 (6) ◽  
pp. 1286-1299 ◽  
Author(s):  
Joan E. Sussman
Keyword(s):  
Working Memory ◽  
Language Learning ◽  
Left Hemisphere ◽  
Language Impairments ◽  
Phonetic Category ◽  
Language Abilities ◽  
Formant Transition ◽  
Place Of Articulation ◽  
Normal Language ◽  
Phonetic Categorization

Discrimination and phonetic identification abilities of 5- to 6-year-old children with language impairments were compared to those of 4-year-olds with normally developing language and to previous findings from 5- to 6-year-olds and adults for synthetic stimuli ranging from [ba] to da]. Results showed similar discrimination sensitivity to the second- and third-formant transition cues of stimuli by all children, with poorest sensitivity by the youngest. Phonetic categorization by children with language impairments was most different from the groups with normal language abilities, evidenced by a difference in the percent of tokens labeled as "BA" and by greater variability in labeling and in placement of phonetic category boundaries. Results support hypotheses by Gathercole and Baddeley (1990) suggesting that the phonological component of working memory may be disordered in children with language impairments. Results are also suggestive of specific difficulties with left-hemisphere processing associated with language learning rather than with problems related to sensitivity to formant transitions of the speech tokens.

Roadblocks to Bilingualism

2019 ◽  
pp. 66-90
Author(s):  
John Evar Strid ◽  
James A. Cohen ◽  
Autumn Gathings ◽  
Raven Stepter ◽  
Amor Taylor
Keyword(s):  
Language Learning ◽  
Teacher Candidates ◽  
Language Abilities ◽  
Heritage Speakers ◽  
Native Languages ◽  
Heritage Speaker ◽  
The Us ◽  
Bilingual Teacher

Most teacher candidates have little experience with learning other languages. They therefore become cogs in the assimilationist machine that causes immigrants to lose native languages and become monolingual in English (Rumbaut, Massey, & Bean, 2006). In a time of devaluing immigrants (and their languages) and failure on the part of most Americans to learn other languages, educators need to focus on the role of other languages in promoting multicultural understanding and to increase language learning in the US. This chapter examines bilingual teacher candidates' experiences with language learning. For four years, students studying for ESL/bilingual licensure were asked to rate their language abilities, finding that 30% rated themselves as bilingual, with 70.43% of bilinguals describing themselves as heritage speakers. The authors report the overall findings as well as the bilingual heritage speaker candidates' own words on their experiences with language learning and maintaining their bilingualism.

Heritage-Language Education for Japanese Children Living Abroad and the Impacts on Their Ethnic Identity

2021 ◽  
pp. 154-176
Author(s):  
Akiko Onda
Keyword(s):  
Ethnic Identity ◽  
Language Learning ◽  
Heritage Language ◽  
Language Education ◽  
Learning Goals ◽  
Japanese Language ◽  
Japanese Children ◽  
Language Abilities ◽  
Education Abroad ◽  
Heritage Language Education

With consistently increasing globalization, the number of Japanese children living and receiving education abroad continues to grow. Previous studies have compared the Japanese-language abilities of children studying Japanese abroad to those of children living in Japan. However, the author contends that the backgrounds of children studying Japanese abroad vary greatly, as do their learning goals. The former do not necessarily want to learn the same language skills as children who study in Japan. Japanese-language education for children living overseas requires that students understand what they want to achieve in terms of their language ability. This chapter focuses on children who have lived and been educated in multiple countries other than Japan; it discusses their Japanese-language learning goals and the environment needed to support those goals. It also examines their sense of ethnic identity as Japanese and how this relates to their upbringing and language-learning experiences.

Assessing young learners’ foreign language abilities

2020 ◽  
Vol 54 (1) ◽  
pp. 1-37 ◽  
Author(s):  
Marianne Nikolov ◽  
Veronika Timpe-Laughlin
Keyword(s):  
Foreign Language ◽  
Language Learning ◽  
Language Proficiency ◽  
Large Scale ◽  
Experimental Studies ◽  
Language Abilities ◽  
Language Programs ◽  
Young Learners ◽  
Foreign Language Programs ◽  
The Impact

AbstractGiven the exponential growth in the popularity of early foreign language programs, coupled with an emphasis of evidence-based instruction, assessing young learners’ (YLs) foreign language abilities has moved to center stage. This article canvasses how the field of assessing young learners of foreign languages has evolved over the past two decades. The review offers insights into how and why the field has developed, how constructs have been defined and operationalized, what language proficiency frameworks have been used, why children were assessed, what aspects of their foreign language proficiency have been assessed, who was involved in the assessment, and how the results have been used. By surveying trends in foreign language (FL) and content-based language learning programs involving children between the ages of 3 and 14, the article highlights research into assessment of and for learning, and critically discusses areas such as large-scale assessments and proficiency examinations, comparative and experimental studies, the impact of assessment, teachers’ beliefs and assessment practices, young learners’ test-taking strategies, age-appropriate tasks, alternative and technology-mediated assessment, as well as game-based assessments. The final section of the article highlights where more research is needed, thus outlining potential future directions for the field.

Learners’ strategies with a grammar application: the influence of language ability and personality preferences

ReCALL ◽  
2007 ◽  
Vol 19 (1) ◽  
pp. 21-38 ◽  
Author(s):  
FENFANG HWU
Keyword(s):  
Language Learning ◽  
Learning Strategies ◽  
Language Ability ◽  
Future Research ◽  
Placement Test ◽  
Language Abilities ◽  
Personality Preferences ◽  
Myers Briggs ◽  
Tracking Ability

This case study investigated the ways pre-major and pre-minor students of Spanish interacted with a grammar application from four perspectives. Firstly, using the computer’s tracking ability to collect learners’ behaviors, the study set out to uncover the different ways learners approached the application. Secondly, the study assessed the influence of two learner variables on learning behaviors: language abilities determined by a placement test and personality preferences measured by Jung-Myers-Briggs-Typology based approach. Thirdly, the study assessed whether the frequency of various behaviors resulted in different knowledge increases. Finally, the study categorized the uncovered behaviors into the learning strategies covered in the Strategy Inventory for Language Learning (SILL) (Oxford 1990). The study concludes with implications for software improvement, as well as with indications of likely directions for future research.

Large-Scale Analysis of Genetic and Clinical Patient Data

2018 ◽  
Vol 1 (1) ◽  
pp. 263-274 ◽  
Author(s):  
Marylyn D. Ritchie
Keyword(s):  
Clinical Data ◽  
Large Scale ◽  
Data Science ◽  
Genomic Analysis ◽  
Genomic Data ◽  
Data Sets ◽  
Biomedical Data ◽  
Data Types ◽  
Phenotypic Data ◽  
Clinical Patient

Biomedical data science has experienced an explosion of new data over the past decade. Abundant genetic and genomic data are increasingly available in large, diverse data sets due to the maturation of modern molecular technologies. Along with these molecular data, dense, rich phenotypic data are also available on comprehensive clinical data sets from health care provider organizations, clinical trials, population health registries, and epidemiologic studies. The methods and approaches for interrogating these large genetic/genomic and clinical data sets continue to evolve rapidly, as our understanding of the questions and challenges continue to emerge. In this review, the state-of-the-art methodologies for genetic/genomic analysis along with complex phenomics will be discussed. This field is changing and adapting to the novel data types made available, as well as technological advances in computation and machine learning. Thus, I will also discuss the future challenges in this exciting and innovative space. The promises of precision medicine rely heavily on the ability to marry complex genetic/genomic data with clinical phenotypes in meaningful ways.

scholarly journals Neural Systems underlying Lexical Competition: An Eye Tracking and fMRI Study

2010 ◽  
Vol 22 (2) ◽  
pp. 213-224 ◽  
Author(s):  
Giulia Righi ◽  
Sheila E. Blumstein ◽  
John Mertus ◽  
Michael S. Worden
Keyword(s):  
Eye Tracking ◽  
Superior Temporal Gyrus ◽  
Visual Display ◽  
Auditory Target ◽  
Neural Systems ◽  
Pictorial Representation ◽  
Conceptual Representation ◽  
Supramarginal Gyrus ◽  
Lexical Competition ◽  
Fmri Study

The present study investigated the neural bases of phonological onset competition using an eye tracking paradigm coupled with fMRI. Eighteen subjects were presented with an auditory target (e.g., beaker) and a visual display containing a pictorial representation of the target (e.g., beaker), an onset competitor (e.g., beetle), and two phonologically and semantically unrelated objects (e.g., shoe, hammer). Behavioral results replicated earlier research showing increased looks to the onset competitor compared to the unrelated items. fMRI results showed that lexical competition induced by shared phonological onsets recruits both frontal structures and posterior structures. Specifically, comparison between competitor and no-competitor trials elicited activation in two nonoverlapping clusters in the left IFG, one located primarily within BA 44 and the other primarily located within BA 45, and one cluster in the left supramarginal gyrus (SMG) extending into the posterior superior temporal gyrus. These results indicate that the left IFG is sensitive to competition driven by phonological similarity and not only to competition among semantic/conceptual factors. Moreover, they indicate that the SMG is not only recruited in tasks requiring access to lexical form but is also recruited in tasks that require access to the conceptual representation of a word.

scholarly journals ODM Clinical Data Generator: Syntactically Correct Clinical Data Based on Metadata Definition

2021 ◽  
Author(s):  
Tobias J. Brix ◽  
Ludger Becker ◽  
Timm Harbich ◽  
Johannes Oehm ◽  
Maximilian Fechner ◽  
...  
Keyword(s):  
Clinical Data ◽  
Web Application ◽  
Clinical Trial Data ◽  
Medical Data ◽  
Data Models ◽  
Clinical Test ◽  
Data Types ◽  
Data Generator ◽  
Definition Of ◽  
Privacy Issues

The Operational Data Model (ODM) is a data standard for interchanging clinical trial data. ODM contains the metadata definition of a study, i.e., case report forms, as well as the clinical data, i.e., the answers of the participants. The portal of medical data models is an infrastructure for creation, exchange, and analysis of medical metadata models. There, over 23000 metadata definitions can be downloaded in ODM format. Due to data protection law and privacy issues, clinical data is not contained in these files. Access to exemplary clinical test data in the desired metadata definition is necessary in order to evaluate systems claiming to support ODM or to evaluate if a planned statistical analysis can be performed with the defined data types. In this work, we present a web application, which generates syntactically correct clinical data in ODM format based on an uploaded ODM metadata definition. Data types and range constraints are taken into account. Data for up to one million participants can be generated in a reasonable amount of time. Thus, in combination with the portal of medical data models, a large number of ODM files including metadata definition and clinical data can be provided for testing of any ODM supporting system. The current version of the application can be tested at https://cdgen.uni-muenster.de and source code is available, under MIT license, at https://imigitlab.uni-muenster.de/published/odm-clinical-data-generator.

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