scholarly journals Can the Bone Mineral Density of the Non-fractured Contralateral Hip Predict Medial Migration of Helical Blade-type Lag Screws in Osteoporotic Hip Fractures?

2020 ◽  
Author(s):  
Suenghwan Jo ◽  
Hyun Jun Lee ◽  
Sang Hong Lee ◽  
Je Hong Ryu ◽  
Ba Rom Kim ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Bone Mineral Density ◽  
Femoral Head ◽  
Bone Mineral ◽  
Mineral Density ◽  
Lag Screw ◽  
Medial Migration ◽  
Femoral Heads ◽  
Helical Blade ◽  
The Mean

Abstract Background: In this study, we performed a biomechanical tests on the osteoporotic femoral heads to validate whether the bone mineral density (BMD) measured at the non-fractured contralateral hip can predict the BMD and potential medial migration of helical blade-type lag screws on the fractured femoral head.Methods: Twenty-four osteoporotic femoral heads were retrieved from patients with femoral neck fracture undergoing hip arthroplasty. The patients had their BMD measured from the contralateral hip using dual-energy X-ray absorptiometry prior to surgery. The BMD of the retrieved femoral heads was measured using micro-computed tomography. The mechanical properties for the medial migration of lag screw were measured by performing an uniaxial compression test on the femoral head using a helical blade-type lag screw. Statistical analysis was performed to determine the correlation among the BMDs of the non-fractured contralateral hip and the retrieved femoral head and the mechanical properties of the fractured femoral head.Results: The mean BMD of the contralateral hip was 0.60±0.14 g/cm2 in the neck region and 0.63±0.15 g/cm2 in the total proximal femur. The mean BMD of the fractured femoral head was 463.3±48.05 mg HA/cm3. The mechanical properties of the fractured femoral head were measured to be 0.92 kN for the maximum compressive load and 14.50±5.48 kN for the accumulated compression load. In the analysis of the correlation among the parameters, we found no correlation between the BMD of the non-fractured contralateral hip and the mechanical properties of the fractured femoral head. In addition, we observed no correlation between the BMD of the fractured femoral head and that of the contralateral hip.Conclusions: Our results indicate that the BMD of the contralateral hip does not reflect the BMD or the mechanical properties of the fractured femoral head. Therefore, helical blade-type lag screw migration may not be predicted from the BMD of the non-fractured contralateral hip.

scholarly journals Bone Mineral Densities and Mechanical Properties of Retrieved Femoral Bone Samples in relation to Bone Mineral Densities Measured in the Respective Patients

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Yvonne Haba ◽  
Ralf Skripitz ◽  
Tobias Lindner ◽  
Martin Köckerling ◽  
Andreas Fritsche ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Bone Mineral Density ◽  
Femoral Head ◽  
Bone Mineral ◽  
Hip Replacement ◽  
Dual Energy ◽  
Femoral Bone ◽  
Mineral Density ◽  
X Ray

The bone mineral density (BMD) of retrieved cancellous bone samples is compared to the BMD measuredin vivoin the respective osteoarthritic patients. Furthermore, mechanical properties, in terms of structural modulus (Es) and ultimate compression strength (σmax) of the bone samples, are correlated to BMD data. Human femoral heads were retrieved from 13 osteoarthritic patients undergoing total hip replacement. Subsequently, the BMD of each bone sample was analysed using dual energy X-ray absorptiometry (DXA) as well as ashing. Furthermore, BMDs of the proximal femur were analysed preoperatively in the respective patients by DXA. BMDs of the femoral neck and head showed a wide variation, from1016±166 mg/cm2to1376±404 mg/cm2. BMDs of the bone samples measured by DXA and ashing yielded values of315±199 mg/cm2and347±113 mg/cm3, respectively.Esandσmaxamounted to232±151 N/mm2and6.4±3.7 N/mm2. Significant correlation was found between the DXA and ashing data on the bone samples and the DXA data from the patients at the femoral head (r=0.85and 0.79, resp.).Escorrelated significantly with BMD in the patients and bone samples as well as the ashing data (r=0.79,r=0.82, andr=0.8, resp.).

scholarly journals SAT0462 ASSESSMENT OF BONE MINERAL DENSITY IN INFLAMMATORY BOWEL DISEASE

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1188.1-1188
Author(s):  
C. Daldoul ◽  
N. El Amri ◽  
K. Baccouche ◽  
H. Zeglaoui ◽  
E. Bouajina
Keyword(s):  
Bone Mineral Density ◽  
Inflammatory Bowel Disease ◽  
Bone Mineral ◽  
Bowel Disease ◽  
Mineral Density ◽  
Femoral Site ◽  
Significant Difference ◽  
History Of ◽  
Inflammatory Bowel ◽  
The Mean

Background:Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn’s disease (CD), is considered as a risk factor of low bone mineral density (BMD). In fact, the prevalence of osteoporosis ranges from 17% to 41% in IBD patients. The possible contributing factors may include malabsorption, glucocorticoid treatment and coexisting comorbiditiesObjectives:The purpose of our work was to determine the frequency and the determinants of osteoporosis in patients with IBD and to assess whether there is a difference in BMD status between UC and CD.Methods:This is a retrospective study, over a period of 5 years (from January 2014 to December 2018) and including patients followed for IBD who had a measurement of BMD by DEXA. Clinical, anthropometric and densitometric data (BMD at the femoral and vertebral site) were recorded. The WHO criteria for the definition of osteoporosis and osteopenia were applied.Results:One hundred and five patients were collected; among them 45 were men and 60 were women. The average age was 45.89 years old. The average body mass index (BMI) was 25.81 kg/m2 [16.44-44.15]. CD and UC were diagnosed in respectively 57.1% and 42.9%. A personal history of fragility fracture was noted in 4.8%. Hypothyroidism was associated in one case. Early menopause was recorded in 7.6%. 46.8% patients were treated with corticosteroids. The mean BMD at the vertebral site was 1.023 g/cm3 [0.569-1.489 g/cm3]. Mean BMD at the femoral site was 0.920g/cm3 [0.553-1.286g / cm3]. The mean T-score at the femoral site and the vertebral site were -1.04 SD and -1.27 SD, respectively. Osteoporosis was found in 25.7% and osteopenia in 37.1%. Osteoporosis among CD and UC patients was found in respectively 63% and 37%. The age of the osteoporotic patients was significantly higher compared to those who were not osteoporotic (52.23 vs 43.67 years, p = 0.01). We found a significantly higher percentage of osteoporosis among men compared to women (35.6% vs 18.3%, p=0.046). The BMI was significantly lower in the osteoporotic patients (23.87 vs 26.48 kg/m2, p=0.035) and we found a significant correlation between BMI and BMD at the femoral site (p=0.01). No increase in the frequency of osteoporosis was noted in patients treated with corticosteroids (27.9% vs 21.6%, p=0.479). Comparing the UC and CD patients, no difference was found in baseline characteristics, use of steroids or history of fracture. No statistically significant difference was found between UC and CD patients for osteoporosis(p=0.478), BMD at the femoral site (p=0.529) and at the vertebral site (p=0.568).Conclusion:Osteoporosis was found in 25.7% of IBD patients without any difference between CD and UC. This decline does not seem to be related to the treatment with corticosteroids but rather to the disease itself. Hence the interest of an early screening of this silent disease.Disclosure of Interests:None declared

Bone mineral density and spongiosa architecture in correlation to vertebral body insufficiency fractures

1998 ◽  
Vol 39 (5) ◽  
pp. 538-542 ◽  
Author(s):  
R. Andresen ◽  
S. Radmer ◽  
D. Banzer
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Vertebral Body ◽  
Unknown Etiology ◽  
Insufficiency Fractures ◽  
Mineral Density ◽  
Group Iii ◽  
Group I ◽  
The Mean ◽  
Group Ii

Objective: the clinical value of spinal quantitative CT (sQCT) and the structural patterns of the vertebral bone were studied Material and Methods: sQCT was performed on 246 patients with a mean age of 57 years for whom conventional lateral radiographies of the thoracic and lumbar spine were available. All patients were suffering from back pain of unknown etiology. the bone mineral density (BMD) of the midvertebral section of 3 lumbar vertebral bodies was determined by means of single-energy-(SE)-weighted QCT (85 kV). Spongiosa architecture and density profile analyses were made in the axial images. This was contrasted to BMD values ascertained in SE QCT. the mean BMD was compared to the number of fractures and the patients were divided into three groups: group I — no fracture; group II — one fracture; and group III 1 fracture Results: the mean BMD was: 134.3 (74.1–187.5) mg hydroxyapatite (HA)/ml in group I; 79.6 (58.6–114.3) mg HA/ml in group II; and 52.4 (13.1–79.1)mg HA/ml in group III. A significant deterioration in spongiosa structure was found with increasing demineralization: strongly rarefied patterns predominated in the fracture groups II and III Conclusion: sQCT provides a good risk assessment of the occurrence of vertebral body insufficiency fractures

scholarly journals Jumping exercise preserves bone mineral density and mechanical properties in osteopenic ovariectomized rats even following established osteopenia

2017 ◽  
Vol 28 (4) ◽  
pp. 1461-1471 ◽  
Author(s):  
R . Okubo ◽  
L. S. Sanada ◽  
V. A. Castania ◽  
M. J. Q. Louzada ◽  
F. J. A. de Paula ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Bone Mineral Density ◽  
Bone Mineral ◽  
Ovariectomized Rats ◽  
Mineral Density ◽  
Jumping Exercise

93 Does Spinal Bone Mineral Density Predict An Absolute 10 Year Probability of Sustaining A Major Osteoporotic Fracture

2021 ◽  
Vol 50 (Supplement_1) ◽  
pp. i12-i42
Author(s):  
A Nandi ◽  
N Obiechina ◽  
A Timperley ◽  
F Al-Khalidi
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Osteoporotic Fracture ◽  
Negative Correlation ◽  
Pearson Correlation ◽  
Fragility Fractures ◽  
Mineral Density ◽  
Major Osteoporotic Fracture ◽  
T Score ◽  
The Mean

Abstract Introduction Spine and hip bone mineral density (BMD) have previously been shown to predict the risk of sustaining future fractures. Although these have been shown in population studies, there is a paucity of trials looking at the relationship between BMD and 10 year probability of major osteoporotic fractures (Using FRAX UK without BMD) in patients with previous fragility fractures. Aims To evaluate the correlation between spinal T-score and an absolute 10 year probability of sustaining a major osteoporotic fracture (using FRAX without BMD) in patients with prior fragility fractures. Methods A retrospective cross-sectional analysis of 202 patients (29 males and 173 females) with prior fragility fractures attending a fracture prevention clinic between January and August 2019 was performed. Patients with pathological and high impact traumatic fractures were excluded. The BMD at the spine was determined using the lowest T-score of the vertebrae from L1 to L4. Using the FRAX (UK) without BMD, the absolute 10 year probability of sustaining a major osteoporotic fracture was calculated for each patient. Statistical analysis was performed using SPSS 26 software. Results The mean T-score at the spine was −1.15 (SD +/− 1.90) for all patients, −0.68 (SD +/− 0.45) for males and − 1.23 (SD +/− 0.14) for females. The mean FRAX score without BMD for major osteoporotic fracture was 18.5% (SD +/− 8.84) for all patients, 11.41% (SD +/−0.62) and 19.7% (SD +/−0.68) for males and females respectively. Pearson correlation coefficient showed a statistically significant, slightly negative correlation between spinal T- score and the FRAX (UK) without BMD (r = −0.157; p < 0.05). Correlation was not statistically significant when males (r = 0.109; p = 0.59) and females (r = 0.148; p = 0.053) were considered independently. Conclusion In patients with prior fragility fracture spinal BMD has a statistically significant negative correlation with an absolute 10 year probability of sustaining a major osteoporotic fracture.

Estimation of Central Osteopenia in Children With Chronic Polyarthritis Treated With Glucocorticoids

PEDIATRICS ◽  
1993 ◽  
Vol 91 (6) ◽  
pp. 1127-1130
Author(s):  
Antero Kotaniemi ◽  
Anneli Savolainen ◽  
Hannu Kautiainen ◽  
Heikki Kröger
Keyword(s):  
Bone Mineral Density ◽  
Lumbar Spine ◽  
Femoral Neck ◽  
Bone Mineral ◽  
Bone Size ◽  
Mineral Density ◽  
Volumetric Density ◽  
Chronic Polyarthritis ◽  
The Mean ◽  
Bone Volumetric Density

Study objective. To investigate the degree and determinants of osteopenia in juvenile chronic polyarthritis. Design. Retrospective case-control study of central bone mineral density. Setting. Rheumatism Foundation Hospital and Kuopio University Hospital, Finland. Subjects. A sample of 43 girls aged 7 to 19 with juvenile chronic polyarthritis treated with systemic glucocorticoids and a control sample of 44 healthy girls matched for age. Main outcome measures. Bone mineral density and bone size (width) measured by dual-energy x-ray absorptiometry and bone volumetric density calculated as an approximation of true bone density at both the lumbar spine and femoral neck. Results. The girls with juvenile chronic arthritis had reduced bone mineral density, bone size, and bone volumetric density at both the lumbar spine and femoral neck (statistically significant findings, P = .022 for the bone size of the femoral neck and P < .001 for the other parameters). At the spine, the mean bone mineral density was 80%, the mean bone size 89%, and the mean bone volumetric density 89% of the values in the control group. At the femoral neck, the values were 78%, 93%, and 83%, respectively. The groups were matched for age, but the girls with arthritis were smaller and lighter. In the juvenile arthritis group, the femoral bone mineral density and bone volumetric density and the spinal bone width correlated negatively with the mean glucocorticoid dose. Conclusion. Axial bone mineral density is clearly reduced in severe juvenile polyarthritis and is mediated by both decreased bone volumetric density and diminished growth.

scholarly journals Heterogeneity of Bone Mineral Density and Fatigue Failure of Human Vertebrae

2012 ◽  
Author(s):  
Yener N. Yeni ◽  
Laila M. Poisson ◽  
Michael J. Flynn
Keyword(s):  
Mechanical Properties ◽  
Bone Mineral Density ◽  
Vertebral Fracture ◽  
Bone Mineral ◽  
Vertebral Fractures ◽  
Important Determinant ◽  
Fatigue Properties ◽  
Static Properties ◽  
Mineral Density ◽  
Significant Interest

Bone qualities that are measurable via clinically available modalities and that can explain fracture risk beyond what is explainable by bone mineral density (BMD) are of significant interest. Evidence from literature suggests that the heterogeneity of BMD within a vertebra, in addition to the average BMD, may be an important determinant of the mechanical properties of a vertebra 1–3 and risk of a clinical vertebral fracture 4. Much of the experimental evidence comes from tests, in which vertebrae are monotonically loaded and relates BMD heterogeneity to the quasi-static properties of a vertebra 1, 3. The appearance of clinical vertebral fractures is in the form of progressive deformities indicating that fatigue processes are involved. However, the relationships between BMD heterogeneity and fatigue properties of a vertebra are not well-understood.

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