Risk of Developing Perforations and Abscesses for Patients With Appendicitis, With Regards to Duration of Symptoms. A Retrospective Cohort Study.

2021 ◽  
Author(s):  
Gunnar Andrésson ◽  
Árný Kristínardóttir
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Perforated Appendicitis ◽  
University Hospital ◽  
Duration Of Symptoms ◽  
National University ◽  
Perforated Appendix ◽  
Prolonged Hospital ◽  
Relationship Of

Abstract ObjectiveSome studies have supported delayed appendectomy citing that the risk of perforation does not increase until beyond 24-48 hours of hospitalization. This retrospective cohort study looked at the relationship of duration of symptoms and the prevalence of perforated appendicitis. To evaluate if a delayed approach would be justifiable.MethodsBetween 1st of January 2018 and 30th of March 2020, there were N=1274 patients, 40 years or younger, suspected of appendicitis at the National University Hospital of Iceland. n=658 had appendicitis and n=105 of them had a perforated appendix. ResultsRelative risk for perforations depending on duration of symptoms were; 6.4, 14.7, 20.2 and 27.1 for 24-48, 48-72, 72-96, and over 96 hours, respectively, compared to 0-24 hours (p < 0.001). There was also a significant correlation with increased duration of symptoms and prolonged hospital stay for patients with appendicitis (p < 0.0001 and rho = 0.36). ConclusionThis indicates that perforations are dependent on the duration of the symptomatic period, and it is probably beneficial to react early and not postpone the workup or treatment past 24 hours.

scholarly journals Assessing the utilization of radiotherapy near end of life at a Finnish University Hospital: a retrospective cohort study

2017 ◽  
Vol 56 (10) ◽  
pp. 1265-1271 ◽  
Author(s):  
Liisa K. Rautakorpi ◽  
Johanna M. Mäkelä ◽  
Fatemeh Seyednasrollah ◽  
Anna M. Hammais ◽  
Tarja Laitinen ◽  
...  
Keyword(s):  
Cohort Study ◽  
End Of Life ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
University Hospital

scholarly journals Diabetes Mellitus as a Risk Factor for Drug Resistance Tuberculosis: A Retrospective Cohort Study at King Abdul Aziz University, Jeddah

2021 ◽  
pp. 136-145
Author(s):  
Sumyia Mehrin M. D. Abulkalam ◽  
Mai Kadi ◽  
Mahmoud A. Gaddoury ◽  
Wallaa Khalid Albishi
Keyword(s):  
Diabetes Mellitus ◽  
Drug Resistance ◽  
Risk Factor ◽  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
University Hospital ◽  
P Value ◽  
Baseline Characteristic ◽  
Drug Resistant

Background: The association between tuberculosis (TB) and diabetes mellitus (DM) is re-emerging with the epidemic of type II diabetes. Both TB and DM were of the top 10 causes of death.[1] This study explores diabetes mellitus as a risk factor for developing the different antitubercular drug-resistant (DR) patterns among TB patients.  Methods: A retrospective cohort study has been conducted on all TB cases reported to the King Abdul Aziz University Hospital, Jeddah, between January 2012 to January 2021. All culture-confirmed and PCR-positive TB cases were included in this study. Categorical baseline characteristic of TB patient has been compared with DM status by using Fisher's exact and Pearson chi-square test. The univariable and multivariable logistic regression model was used to estimate the association between DM and different drug resistance patterns.  Results: Of the total 695 diagnosed TB patients, 92 (13.24%) are resistant to 1st line anti TB drugs. Among 92 DR-TB patients, 36 (39.13%) are diabetic. The percentage of different patterns of DR-TB with DM, in the case of mono DR (12.09%), poly DR (4.19%) MDR (0.547%). As a risk factor, DM has a significant association with DR-TB, mono drug-resistant, and pyrazinamide-resistant TB (P-value <0.05). The MDR and PDR separately do not show any significant association with DM, but for further analysis, it shows a significant association with DM when we combined.  Conclusion: Our study identified diabetes mellitus as a risk factor for developing DR-TB. Better management of DM and TB infection caring programs among DM patients might improve TB control and prevent DR-TB development in KSA.

scholarly journals Frequency of Breakfast, Lunch, and Dinner and Incidence of Proteinuria: A Retrospective Cohort Study

Nutrients ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 3549
Author(s):  
Ryohei Tomi ◽  
Ryohei Yamamoto ◽  
Maki Shinzawa ◽  
Yoshiki Kimura ◽  
Yoshiyuki Fujii ◽  
...  
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Close Association ◽  
Observational Period ◽  
Cardiometabolic Diseases ◽  
Hazard Ratios ◽  
National University ◽  
Skipping Breakfast ◽  
Male Workers

Although multiple studies have revealed a close association of skipping breakfast with cardiometabolic diseases, few studies have reported its association with chronic kidney disease (CKD). Furthermore, there is scant reporting on the clinical impacts that skipping lunch and dinner has on cardiometabolic diseases and CKD. This retrospective cohort study, including 5439 female and 4674 male workers of a national university in Japan who underwent annual health checkups between January 2005 and March 2013, aimed to assess an association of frequencies of breakfast, lunch, and dinner with incidence of proteinuria (dipstick urinary protein ≥1+). The incidence of proteinuria was observed in 763 (14.0%) females and 617 (13.2%) males during the median 4.3 and 5.9 years of the observational period, respectively. In females, skipping breakfast as well as skipping dinner, but not lunch, were associated with the incidence of proteinuria (adjusted hazard ratios of breakfast frequency of “every day”, “sometimes”, and “rarely”: 1.00 (reference), 1.35 (1.09–1.66), and 1.54 (1.22–1.94), respectively; those of dinner frequency of “every day” and “≤sometimes”: 1.00 (reference) and 1.31 (1.00–1.72), respectively). However, no association was observed in male workers. Skipping breakfast and skipping dinner were identified as risk factors of proteinuria in females, but not in males.

Sign in / Sign up

Export Citation Format

Share Document