Enhancement of Dendritic Cell-Based Immunotherapy Using a Small Molecule TGF-beta Receptor Type I Kinase Inhibitor

Enhancement of Dendritic Cell-Based Immunotherapy Using A Small Molecule TGF-?? Receptor Type I (TGF-??RI) Kinase Inhibitor

Journal of Immunotherapy ◽

10.1097/01.cji.0000191075.57371.3b ◽

2005 ◽

Vol 28 (6) ◽

pp. 651

Author(s):

Matthew P Rausch ◽

Daruka Mahadevan ◽

Emmanuel T Akporiaye

Keyword(s):

Dendritic Cell ◽

Small Molecule ◽

Kinase Inhibitor ◽

Receptor Type ◽

Type I

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Inhibition of Natural Type I IFN-Producing and Dendritic Cell Development by a Small Molecule Receptor Tyrosine Kinase Inhibitor with Flt3 Affinity

The Journal of Immunology ◽

10.4049/jimmunol.175.6.3674 ◽

2005 ◽

Vol 175 (6) ◽

pp. 3674-3680 ◽

Cited By ~ 40

Author(s):

Roxane Tussiwand ◽

Nobuyuki Onai ◽

Luca Mazzucchelli ◽

Markus G. Manz

Keyword(s):

Dendritic Cell ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Small Molecule ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitor ◽

Type I ◽

Type I Ifn ◽

Receptor Tyrosine Kinase Inhibitor ◽

Natural Type

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Effects of TGF-$beta;1/IFN-$gamma; on expression of TGF-$beta; receptor type I of rat VSMC

American Journal of Hypertension ◽

10.1016/s0895-7061(03)00574-0 ◽

2003 ◽

Vol 16 (5) ◽

pp. A183

Author(s):

G DING

Keyword(s):

Receptor Type ◽

Type I ◽

Tgf Beta ◽

Ifn Gamma ◽

Beta Receptor

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P0320 : Targeting TGF-beta I with the transforming growth factor receptor type I kinase inhibitor, LY2157299, modulates stemness-related biomarkers in hepatocellular carcinoma

Journal of Hepatology ◽

10.1016/s0168-8278(15)30535-3 ◽

2015 ◽

Vol 62 ◽

pp. S429 ◽

Cited By ~ 1

Author(s):

B. Rani ◽

F. Dituri ◽

Y. Cao ◽

U. Engström ◽

L. Lupo ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Growth Factor ◽

Transforming Growth Factor ◽

Kinase Inhibitor ◽

Growth Factor Receptor ◽

Receptor Type ◽

Type I ◽

Tgf Beta ◽

Transforming Growth Factor Receptor

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Identification of a small molecule kinase inhibitor that enhances osteoblast differentiation of human skeletal (mesenchymal) stem cells through regulation of TGF[beta] signaling

Bone Abstracts ◽

10.1530/boneabs.1.pp175 ◽

2013 ◽

Author(s):

Majken Storm Siersbaek ◽

Abbas Jafari ◽

Walid Zaher ◽

Li Chen ◽

Moustapha Kassem

Keyword(s):

Stem Cells ◽

Mesenchymal Stem Cells ◽

Small Molecule ◽

Osteoblast Differentiation ◽

Kinase Inhibitor ◽

Tgf Beta ◽

Small Molecule Kinase Inhibitor

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Faculty Opinions recommendation of Human uterine leiomyoma-derived fibroblasts stimulate uterine leiomyoma cell proliferation and collagen type I production, and activate RTKs and TGF beta receptor signaling in coculture.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.3677956.3399054 ◽

2010 ◽

Author(s):

Phyllis Leppert

Keyword(s):

Cell Proliferation ◽

Uterine Leiomyoma ◽

Collagen Type ◽

Collagen Type I ◽

Type I ◽

Receptor Signaling ◽

Tgf Beta ◽

Beta Receptor

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Growth inhibition by transforming growth factor beta (TGF-beta) type I is restored in TGF-beta-resistant hepatoma cells after expression of TGF-beta receptor type II cDNA.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.90.11.5359 ◽

1993 ◽

Vol 90 (11) ◽

pp. 5359-5363 ◽

Cited By ~ 118

Author(s):

M. Inagaki ◽

A. Moustakas ◽

H. Y. Lin ◽

H. F. Lodish ◽

B. I. Carr

Keyword(s):

Growth Factor ◽

Growth Inhibition ◽

Transforming Growth Factor Beta ◽

Transforming Growth Factor ◽

Hepatoma Cells ◽

Receptor Type ◽

Type I ◽

Type Ii ◽

Tgf Beta ◽

Growth Factor Beta

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Abstract 4568: A novel TGF-beta receptor I kinase inhibitor demonstrated to be an effective immuno-therapy for cancer

10.1158/1538-7445.am2017-4568 ◽

2017 ◽

Author(s):

Zusheng Xu ◽

Yangtong Lou ◽

Li Chen ◽

Kun Zeng ◽

Qingrui Sun ◽

...

Keyword(s):

Kinase Inhibitor ◽

Tgf Beta ◽

Beta Receptor

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Abstract A073: TGF-beta receptor type-2 expression regulates breast cancer progression and is a prognostic marker for racial disparities

10.1158/1538-7755.disp19-a073 ◽

2020 ◽

Author(s):

Alakesh Bera ◽

John Karaian ◽

Harvey B Pollard ◽

Hai Hu ◽

Craig D Shriver ◽

...

Keyword(s):

Breast Cancer ◽

Racial Disparities ◽

Prognostic Marker ◽

Cancer Progression ◽

Breast Cancer Progression ◽

Receptor Type ◽

Tgf Beta ◽

Beta Receptor

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Cloning of a type I TGF-beta receptor and its effect on TGF-beta binding to the type II receptor

Science ◽

10.1126/science.8388127 ◽

1993 ◽

Vol 260 (5112) ◽

pp. 1344-1348 ◽

Cited By ~ 259

Author(s):

R Ebner ◽

R. Chen ◽

L Shum ◽

S Lawler ◽

T. Zioncheck ◽

...

Keyword(s):

Type I ◽

Type Ii ◽

Tgf Beta ◽

Beta Receptor

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