Barrier to Treatment in Patients with Neurotic, Stress Related and Somatoform Disorders: Study from A Tertiary Centre of North India

Background: Various studies have found the overall incidence of cutaneous adverse drug reactions (CADR’s) in developed countries as 1-3%, while the incidence in developing countries is thought to be higher between 2 and 5%. FDEs’ share is seen to be about 15 -30% of all CADR’s as reported in various studies. Aim of the research work was to study the clinical and epidemiological features of fixed drug eruptions and to identify probable culprit drug or drugs using Naranjo ADR probability scale and to provide information to the patient regarding the drug responsible for his/her drug rash.Methods: A total of 180 patients of fixed drug eruptions were taken up for study who presented to skin OPD at a tertiary centre of North India. Diagnosis was made on the basis of history of drug intake prior to drug eruption, repetition of similar lesions on same as well as new sites on intake of same drug with improvement of skin lesions on discontinuation of the causative drug. Further on examination, skin lesions with typical morphology compatible with FDE were seen. Causality of the FDE was assessed according to the NARANJO ADR probability scale.Results: A total of 180 patients of FDE were studied. Males outnumbered the females. The most common class of drug implicated was antimicrobials seen in 115 patients followed by NSAIDS 65 patients. Regarding the clinical presentation both skin and mucosal involvement was seen. The most common skin lesions were erythematous to hyperpigmented and violaceous macules followed by bullous FDE.Conclusions: In summary, early recognition of FDE is important not only for the dermatologists but also for the clinicians of other specialties, so that the culprit drug is recognized and stopped immediately. Drug reactions are a common reason for litigation and has medicolegal pitfalls.

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Incidence of steroid modified tinea in pediatric age group at tertiary centre in North India

International Journal of Research in Dermatology ◽

10.18203/issn.2455-4529.intjresdermatol20213343 ◽

2021 ◽

Vol 7 (5) ◽

pp. 677

Author(s):

Savita Chaudhary ◽

Chandni Jain ◽

Gaurav Paliwal ◽

Priyanka Shukla

Keyword(s):

Common Species ◽

North India ◽

Topical Steroids ◽

Age Group ◽

Pediatric Age ◽

Atypical Form ◽

Pediatric Age Group ◽

Tertiary Centre ◽

History Of ◽

Common Variety

Background: Uncontrolled use and abuse of topical steroids has led to increase in number of cases of superficial dermatophytosis of skin, hair and nail in pediatric age group as well. Our study aimed to analyse epidemiological and microbiological profile of steroid modified tinea (SMT) in pediatric age group.Methods: Clinically diagnosed tinea childhood patients with history of usage of topical steroids in children were included in our study. Detailed history was taken and clinical examination along with KOH mount and culture was done.Results: 112 patients were clinically diagnosed as tinea out of which 61cases gave the history of topical steroids and were included in our study. Most common age group was 12-18 years with female:male of ratio approximately 3:1 and disseminated and atypical form was the most common variety. KOH mount was positive in 73.2% cases and culture was positive in 69.6% cases. Most common species found out to be Tinea mentagrophytes followed by Tinea rubrum. Among non-dermatophyte group, Candida was the commonest.Conclusions: There is rise in incidence of dermatophytosis, especially steroid modified, atypical and disseminated.

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Antenatal, intranatal and postnatal care: a tertiary centre study of North India

International Journal of Community Medicine and Public Health ◽

10.18203/2394-6040.ijcmph20182185 ◽

2018 ◽

Vol 5 (6) ◽

pp. 2500

Author(s):

Anjali Gupta ◽

Anish Khanna ◽

Rekha Sachan ◽

V. K. Singh ◽

O. P. Singh

Keyword(s):

Multivariate Logistic Regression Analysis ◽

Normal Growth ◽

Cross Sectional Study ◽

Normal Weight ◽

North India ◽

Growth Data ◽

Cross Sectional ◽

Mortality And Morbidity ◽

Factors Affecting ◽

Tertiary Centre

Background:Care of pregnant lady during antenatal period is the key to reducing maternal mortality and morbidity during pregnancy and child birth and futher improving the growth and development of the newborn. Optimal weight gain in the initial 6 months is very essential. Therefore, study aims to assess antenatal, intranatal and postnatal factors affecting the growth of newborn child. Methods:A Community based cross sectional study was conducted twice – at delivery and second after 6 months. A total of 220 ladies delivered at QMH, King Georges Medical University, Lucknow between August-2016 to September-2017 were included. WHO Standards were used to calculate the deviation from normal growth. Data was entered in SPSS-23 and assessment was made for factors affecting the growth of newborn. Results:At the time of birth the weight, length and head circumference of newborn was measured. Normal weight, length and H.C of ±2 SD was seen in 91%, 88%, 94% males respectively and 87.8%, 97.8 and 73.3% females. Repeat measurements at 6 month age of newborn showed normal weight, length and H.C in 62%, 58% and 87% males respectively and 87.8%, 74.4% and 96.7% females. Multivariate logistic regression analysis of factors revealed that growth of newborn upto 6 months was significantly associated with exclusive breastfeeding (OR 0.161; 95% CI 0.053-0.492; p=0.001), Illness in past 6 months (OR 6.820; 95%CI 2.376-19.579; p<0.001) low birth weight (OR 0.101; 95% CI 0.015-0.665; p=0.017). Conclusions:Although adherence to the proper schedule of antenatal, intranatal and postnatal visits and care varies between individuals and over time, the factors can be addressed with periodic counselling and motivation of pregnant ladies and their families.

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