scholarly journals Comparative Study of Diabetic Retinopathy by Means of Clinical Evaluation of Fundus and Fundus Fluorescein Angiography among Diabetic Patients Less than 10 Years of Diabetic Age

Author(s):  
Vinit Rewanwar ◽  
B. S. Joshi
2020 ◽  
Vol 11 (3) ◽  
pp. 3240-3250
Author(s):  
Vinit Umesh Rewanwar ◽  
Joshi B.S.

People with diabetes complications under many tests. For diabetic retinopathy, we do many tests like, ophthalmoscopy which is done in clinical examination & Fundus Fluorescein Angiography (FFA), etc. This study has been conducted to evaluate the use of Fundus fluorescein angiography in DM patients and its comparison with clinical evaluation for early detection and assessment of the stage of diabetic retinopathy. The current study looked for ophthalmology and the diagnostic potential of FFA in the diagnosis of ophthalmic retinopathy findings because both facilities may not be available everywhere. So look for and provide better options for diagnosis of diabetic retinopathy. Diabetic maculopathy is also a clear finding on direct eye examination. We found that there was a significant correlation between the age groups of the patients: Diabetes, and the development of diabetic retinopathy. No significant association with the sex of patients was observed in the event of retinopathy. In diabetic patients younger than five years of age or those who are in the early stage of diabetic retinopathy, we found that the initial pathological changes that could not be seen on ophthalmoscopy were evident on FFA. The procedure is useful in diagnosis, treatment, follow-up of patients, maintain a permanent record of the retinopathy staging, study the course of the disease, and response to the procedure.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Xiaoli Li ◽  
Jie Xie ◽  
Liang Zhang ◽  
Ying Cui ◽  
Guanrong Zhang ◽  
...  

Abstract Background To analyze the distribution of manifest lesions of diabetic retinopathy (DR) by fundus fluorescein angiography (FFA) and color fundus photography (FP). Methods A total of 566 eyes of 324 Chinese patients diagnosed with DR were included in this retrospective study. DR severity was graded by the international grading criterion. The distributions of microaneurysms (MA), intraretinal hemorrhages/exudates (He/Ex), intraretinal microvascular abnormality (IRMA), capillary nonperfusion areas (NPA), and neovascularization (NV) were estimated by multiple logistic regression analyse based on nine-field FFA and FP images. Results In mild nonproliferative diabetic retinopathy (NPDR), the highest frequency of MA was found in the posterior pole (67.7%), followed by the inferior nasal (59.4%), and the nasal (55.4%) fields. In moderate NPDR, MA frequently distributed in the posterior pole (98.0%), nasal (97.0%), superior (96.0%), inferior nasal (94.9%), and inferior (92.9%) fields, whereas He/Ex were most prevalent in the posterior pole (69.7%). In severe NPDR and proliferative DR, IRMA, NPA, and NV were more frequent in the nasal field, particularly in the inferior nasal field (60.3, 38.7, and 76.0%, respectively). All lesions were more observed in the combined posterior pole, nasal, and inferior nasal fields than in the posterior pole or combined two fields in the early and severe stages of DR (P < 0.05). Conclusions The manifest lesions of DR were common in the nasal field besides the posterior pole in Chinese patients. A combined examination of the posterior pole, nasal, and inferior nasal mid-peripheral retina would help to detect different retinal lesions of DR. Trial registration ClinicalTrial. gov, NCT03528720. Registered 18 May 2018 - Retrospectively registered.


Diabetic retinopathy is an important public health issue as its prevalence has been increasing every year. It is one of the major causes of visual loss which can be preventable with early diagnosis and appropriate treatment. The fundus examination must be done in detail using mydriatics, and digital images must be recorded in all diabetic patients with special emphasis on the disease type (type I and type II), duration, and prognosis. Fluorescein angiography (FA) is a gold standard invasive retinal imaging technique for the diagnosis, monitoring, and evaluating the response of the treatment in diabetic patients, but FA has limitations due to possible side effects. Optical coherence tomography angiography (OCTA) is a recent, non-invasive, dye-free imaging technique that can be used in every visit. It has the capability to image all retinal and choroidal vascular layers (segmentation) and quantify macular ischemia in a short period of time which is beneficial for the patient, and the ophthalmologist. The aim of this review is to address the findings, advantages, and disadvantages of FA and OCTA in patients with diabetic retinopathy and diabetic macular edema.


Author(s):  
Bheema Patil ◽  
Pankaj Puri

The chapter begins by discussing key clinical skills, namely fundus fluorescein angiography, abnormal fluorescein angiography, indocyanine green angiography, and electrophysiology. The following areas of clinical knowledge are then discussed: diabetic retinopathy, hypertensive retinopathy, retinal vein occlusion, retinal artery occlusions, age-related macular degeneration, intravitreal anti-VEGF injections, central serous chorioretinopathy, retinal vascular anomalies, retinal dystrophies, and choroidal dystrophies. The chapter concludes with eight case-based discussions, on gradual visual loss, central visual loss, visual loss in a hypertensive patient, sudden, painless visual loss, diabetic retinopathy, difficult night vision, visual loss in child, and macular lesion.


2021 ◽  
pp. 112067212110087
Author(s):  
Yifeng Ke ◽  
Heng Zhang ◽  
Kaiwen Hei ◽  
Yi Shi ◽  
Xiaorong Li ◽  
...  

Purpose: This study aimed to evaluate the relationship between diabetic iridopathy (DI) and diabetic retinopathy (DR) and distinguish iris neovascular and physiological leakage using iris fluorescein angiography (IFA). Methods: A total of 210 subjects were prospectively recruited in this study. Sixty normal subjects were divided equally into three groups (<40 years old, 40–59 years old, and 60–79 years old). One hundred fifty patients with diabetic mellitus (DM) were divided equally into five groups (no retinopathy, mild non proliferative DR (mildnPDR), moderate nPDR, severe nPDR, and PDR group). Normal subjects underwent IFA. Patients with DR underwent both IFA and ultrawide field fundus fluorescein angiography (uwFFA) at the same time. The leakage time and area were recorded and compared with each group. Results: Fluorescein leakage occurred at the pupillary edge of patients that were 40–59 and 60–79 years old but not in those <40 years old. In the PDR group, the leakage time was earlier and the leakage area was larger than nPDR and patients with no retinopathy ( p = 0.039 and p = 0.005, respectively). However, the leakage time and area were not significantly different between patients with no retinopathy and nPDR ( p > 0.05). Conclusion: IFA examination can only assist in estimating the fundus severity of PDR patients, whereas the fundus changes of patients with no retinopathy and nPDR were not related to DI changes. Trial registration No.: ChiCTR1800018003. The date of registration: Aug 26th, 2018.


2018 ◽  
Vol 6 (2) ◽  
pp. 93-101
Author(s):  
Dr. Sapna Raghuwanshi ◽  
◽  
Dr. Rashmi Kumar ◽  
Dr. Shivkumar Raghuwanshi ◽  
◽  
...  

2020 ◽  
Vol 15 (02) ◽  
pp. 122-133
Author(s):  
Rainer Guthoff

AbstractThe frequency of diabetic retinopathy increases and is a leading cause of blindness in the working population. Recommended exams are testing of the visual acuity, ophthalmoscopy with dilated pupils, fundus fluorescein angiography and optical coherence tomography (OCT). By OCT the diagnosis and monitoring of diabetic macular edema has vastly improved. By intravitreal medications such as intravitreal anti-VEGF or intravitreal steroids macular edema can be treated successfully. Panretinal laser photocoagulation is the gold-standard in the therapy of proliferative diabetic retinopathy. Patients benefit from good co-working of general practitioner and ophthalmologist concerning screening and treatment.


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