scholarly journals Effect of gene environment interactions on lung function and cardiovascular disease in COPD

Author(s):  
Hackett ◽  
Stefanowicz ◽  
Aminuddin ◽  
Don Sin ◽  
Connett ◽  
...  
2014 ◽  
Vol 108 (12) ◽  
pp. 1779-1785 ◽  
Author(s):  
Hwa Mu Lee ◽  
Michael A. Liu ◽  
Elizabeth Barrett-Connor ◽  
Nathan D. Wong

2021 ◽  
Vol 23 (12) ◽  
Author(s):  
Jaana A. Hartiala ◽  
James R. Hilser ◽  
Subarna Biswas ◽  
Aldons J. Lusis ◽  
Hooman Allayee

2003 ◽  
Vol 253 (5) ◽  
pp. 574-581 ◽  
Author(s):  
G. Engstrom ◽  
B. Hedblad ◽  
P. Nilsson ◽  
P. Wollmer ◽  
G. Berglund ◽  
...  

Author(s):  
Khouloud Kchaou ◽  
Ahmed Ben Ayed ◽  
Asma Chaker ◽  
Soumaya Khaldi ◽  
Salma Mokaddem ◽  
...  

2004 ◽  
Vol 4 (03) ◽  
pp. 265-270
Author(s):  
Eric J. Sijbrands ◽  
Geesje Dallinga-Thie ◽  
Janneke G Langendonk

2021 ◽  
Vol 22 (8) ◽  
pp. 4182
Author(s):  
Michal Vrablik ◽  
Dana Dlouha ◽  
Veronika Todorovova ◽  
Denes Stefler ◽  
Jaroslav A. Hubacek

Despite the rapid progress in diagnosis and treatment of cardiovascular disease (CVD), this disease remains a major cause of mortality and morbidity. Recent progress over the last two decades in the field of molecular genetics, especially with new tools such as genome-wide association studies, has helped to identify new genes and their variants, which can be used for calculations of risk, prediction of treatment efficacy, or detection of subjects prone to drug side effects. Although the use of genetic risk scores further improves CVD prediction, the significance is not unambiguous, and some subjects at risk remain undetected. Further research directions should focus on the “second level” of genetic information, namely, regulatory molecules (miRNAs) and epigenetic changes, predominantly DNA methylation and gene-environment interactions.


1994 ◽  
Vol 139 (11) ◽  
pp. 1066-1076 ◽  
Author(s):  
Nancy R. Cook ◽  
Patricia R. Hebert ◽  
Suzanne Satterfield ◽  
James O. Taylor ◽  
Julie E. Buring ◽  
...  

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