scholarly journals The Clinical Value of the RA-Adjusted Fracture Risk Assessment Tool in the Fracture Risk Prediction of Patients with Type 2 Diabetes Mellitus in China

2021 ◽  
Vol Volume 14 ◽  
pp. 327-333
Author(s):  
Ling Hu ◽  
Ting Li ◽  
Yi Zou ◽  
Xiao-Ling Yin ◽  
Hui Gan
2020 ◽  
Vol 20 (1) ◽  
pp. 15-21
Author(s):  
Aung Myo Oo ◽  
Al-abed Ali Ahmed Al-abed ◽  
Ohn Mar Lwin ◽  
Sowmya Sham Kanneppady ◽  
Tee Yee Sim ◽  
...  

Type 2 diabetes mellitus (DM) is becoming major health threat worldwide and it is extremely common in clinical setting. Malaysia is one of the highest diabetic populations among Asian countries and the new cases are increasing day to day. Early detection of people with high risk of Type 2 DM by using simple, easy and cost-effective assessment tool is the better way to identify and prevent the community from this non-communicable disease. The objectives of the study were to identify those are high risk to become type 2DM among Malaysians by using risk scoring form and to educate them how to prevent it. Total 591 subjects were recruited from the health screening programs carried out by the collaboration of Petaling Jaya Development Council (MBPJ) and Lincoln University College, Malaysia. Modified form of Finnish Type 2 Diabetes Risk Assessment Tool was used to identify people at risk of becoming type 2 DM. Descriptive analysis was performed for all included variables in this study by using SPSS version 21. The study found out that almost half of the participants were found to have family history of DM, 60% of them were overweight and obese and 47% were having above normal waist circumference. We observed that nearly 60 % of participants in the study were having moderate to high risk of becoming type 2 DM in next 10 years. To conclude, the result of our study would be helpful in implementation of cost-effective, convenient Type 2 DM risk assessment tool which has yet to be implemented in Malaysia.


Author(s):  
Fenghui Pan ◽  
Wenxia Cui ◽  
Lei Gao ◽  
Xiaoting Shi ◽  
Mingrui Zhang ◽  
...  

Abstract Purpose To develop a simple and clinically useful assessment tool for osteoporosis in older women with type 2 diabetes mellitus (T2DM). Methods A total of 601 women over 60 years of age with T2DM were enrolled in this study. The levels of serum sex hormones and bone metabolism markers were compared between the osteoporosis and non-osteoporosis groups. The least absolute shrinkage and selection operator regularization (LASSO) model was applied to generate a risk assessment tool. The risk score formula was evaluated using receiver operating characteristic analysis and the relationship between the risk score and the bone mineral density (BMD) and T-value were investigated. Results Serum sex hormone-binding globulin (SHBG), cross-linked C-telopeptide of type 1 collagen (CTX), and osteocalcin (OC) were significantly higher in the osteoporosis group. After adjustment for age and body mass index (BMI), SHBG was found to be correlated with the T-value or BMD. Then, a risk score was specifically generated with age, BMI, SHBG, and CTX using the LASSO model. The risk score was significantly negatively correlated with the T-value and BMD of the lumbar spine, femoral neck, and total hip (all P<0.05). Conclusion A risk score using age, BMI, SHBG, and CTX performs well for identifying osteoporosis in older women with T2DM.


2020 ◽  
Vol 360 (5) ◽  
pp. 552-559
Author(s):  
Masahiro Ohira ◽  
Sawako Suzuki ◽  
Tomohiko Yoshida ◽  
Hisashi Koide ◽  
Tomoaki Tanaka ◽  
...  

2013 ◽  
pp. 1-1
Author(s):  
Gbadebo Ajani ◽  
Rosemary Ikem ◽  
Adenike Enikuomehin ◽  
David Soyoye ◽  
Babatope Kolawole

2020 ◽  
Vol 103 (11) ◽  
pp. 1131-1137

Background: When compared to people without type 2 diabetes mellitus (T2DM), people with T2DM have an increase in fracture risk despite having higher bone mineral density (BMD). Many studies in Caucasians demonstrated that trabecular bone score (TBS) is lower in people with T2DM than those without. The utility of TBS as a fracture risk assessment tool in Asians with T2DM is currently unclear. Objective: To compared lumbar spine (LS) BMD and TBS in Thais with or without T2DM and investigate the correlation between TBS and hemoglobin A1c (HbA1c) and diabetes duration in participants with T2DM. Materials and Methods: The present study was a cross-sectional study that included 97 participants with T2DM (37 men and 60 women) and 342 participants without T2DM (174 men and 168 women). LS-BMD and TBS were obtained. Results: Men and women with T2DM were older and had higher body mass index (BMI). Men with T2DM had significant higher LS-BMD (1.051±0.166 versus 0.972±0.125, p=0.009) and non-significant lower TBS (1.333±0.084 versus 1.365±0.096, p=0.055) than those without. Similarly, women with T2DM had significant higher LS-BMD (0.995±0.155 versus 0.949±0.124, p=0.021) and lower TBS (1.292±0.105 versus 1.382±0.096, p<0.001). After adjusting for age and BMI, T2DM predicted higher BMD in men (p<0.001), but not in women (p=0.143). T2DM was not associated with TBS after adjusting for age and BMI in both genders (p=0.403 and p=0.151 in men and women, respectively). TBS did not correlate with HbA1c in both genders. However, TBS was non-significantly associated with diabetes duration in women (p=0.073), but not in men (p=0.639). Conclusion: T2DM significantly predicted higher LS-BMD only in men and was not independently associated with TBS in both genders. These data highlighted that, in T2DM, there was some variation in the clinical usefulness of BMD and TBS in predicting osteoporotic fractures with regard to clinical characteristic of participants. Keywords: Bone mineral density, Type 2 diabetes mellitus, Trabecular bone score


2021 ◽  
Vol 6 (3) ◽  
pp. 407-412
Author(s):  
Leena Dorothy W ◽  
Pavithra C ◽  
Umadevi A K

Objective: Stroke is a major public health problem, both in developed and developing countries. Stroke is becoming an important cause of early death and disability in India due to increasing prevalence of the major key modifiable risk factors like type 2 diabetes mellitus and hypertension. Hence there is an urgent need for recognition of stroke risk factors and its warning signs. With this intention the present study aimed to assess the risk of stroke among patients with hypertension and type 2 diabetes mellitus. Methods: A non-experimental, descriptive survey method was adopted. Samples were selected by using quota sampling technique and 60 hypertensive and type 2 diabetes mellitus patients who met the inclusion criteria were selected for the study. Data were collected by an interview technique using a modified stroke risk assessment tool by the National Stroke Association, USA. Results: Out of 60 samples 48.3% of them were in high-risk category, 28.3% were in caution and 23.3% in low-risk category. There was a significant association found in relation to socio demographic variables such as education qualification, type of family, type of diet, weight and complications of hypertension (P<0.05). Discussion: The findings of the study suggested that there is an increased risk of stroke in hypertension and type 2 diabetes patients which can be aggravated by other risk factors and co-morbid conditions. Hence modifying these risk factors by changing lifestyle can help in prevention of stroke. Keywords: Stroke, risk assessment, hypertension and type 2 diabetes mellitus, comorbid conditions.


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