scholarly journals Total Knee Arthroplasty Postsurgical Chronic Pain, Neuropathic Pain, and the Prevalence of Neuropathic Symptoms: A Prospective Observational Study in Turkey

2021 ◽  
Vol Volume 14 ◽  
pp. 1315-1321
Author(s):  
Fatih Şahin ◽  
Serbülent Gökhan Beyaz ◽  
Nazım Karakuş ◽  
Mustafa Erkan İnanmaz
2020 ◽  
Vol 48 (11) ◽  
pp. 030006052096930
Author(s):  
Chenrong Ke ◽  
Naifeng Tian ◽  
Xiumeng Zhang ◽  
Mochuan Chen

Objective This study was performed to depict the patterns of change in the perioperative hemoglobin (Hb) concentration and hematocrit (Hct) and to identify the optimal timing of Hb and Hct measurement in patients undergoing total knee arthroplasty (TKA). Methods This prospective observational study involved 302 consecutive patients who underwent TKA. The patients were kept in hospital for 1 full week postoperatively. Hb and Hct measurements were performed preoperatively and on days 1 to 7 postoperatively and then during clinic visits at 1, 3, and 6 months postoperatively. Results The Hb concentration and Hct decreased during the first few days postoperatively and reached a nadir on postoperative day 4 and 3, respectively; they then recovered in the following days. Significant differences in the Hb concentration and Hct were detected between the preoperative period and day 1, between days 1 and 2, between days 2 and 3, between day 7 and 1 month, and between 1 and 3 months. A significant difference in the Hct was also detected between 3 and 6 months. Conclusion The optimal timing of Hb and Hct measurement is on postoperative day 3 or 4. This timing accurately reflects ongoing hidden blood loss to better guide blood transfusions.


Author(s):  
Richard M. Langford

The paper discussed in this chapter, published in 2010 by Buvanendran et al. is entitled ‘Perioperative oral pregabalin reduces chronic pain after total knee arthroplasty: a prospective, randomized, controlled trial.’ Chronic (or persistent) post-surgical pain is defined as pain that develops after surgical intervention and lasts at least 2 months; other causes being excluded, in particular pain from a condition preceding surgery. The subject of the commentary reviewed in this chapter is a study conducted in 2006–7, regarded as a pivotal step to establish the role of gabapentinoids, and in particular pregabalin, for both perioperative pain management and prevention of chronic post-surgical neuropathic pain, specifically persisting neuropathic pain after total knee arthroplasty.


2021 ◽  
Vol Volume 14 ◽  
pp. 133-139
Author(s):  
Mohammed Alisi ◽  
Jihad Al-Ajlouni‎ ◽  
Mohammed Kareem Ibsais‎ ◽  
Zeinab Obeid‎ ◽  
Yazan Hammad‎ ◽  
...  

2020 ◽  
Author(s):  
Chenrong Ke ◽  
Naifeng Tian ◽  
Xiumeng Zhang ◽  
Mochuan Chen

Abstract Background Total knee arthroplasty (TKA) has long been associated with significant blood loss, hence postoperative hemoglobin (Hb) and hematocrit (Hct) determination remains necessary for evaluating blood loss and guiding transfusions. The aim of the study was to depict the changing patterns of perioperative Hb and Hct levels and to identify an optimal timing of determination in patients receiving TKA surgeries. Methods This was a prospective observational study by recruiting a total of 302 consecutive patients who received TKA surgeryfor final analysisfrom January 2017 until December 2018. Patients were kept in hospital for a full week postoperatively to detect a preoperative, postoperative day1 through to day7 Hb and Hct concentrations, postoperative 1-month, 3-months and 6-monthsvalues were followed up in the clinic visiting. Results Hb and Hct levels decreased in the first few days and reached a nadir on postoperative day4 and day3 respectively while recovered in the following days and approached to preoperative values at postoperative 3-months. The mean maximum drop of Hb and Hct concentrations was detected as 4.0g/dL and 11.5%separately. Significant differences were detected on Hb and Hct concentrations between the timing neighbors on preoperative vs. day1, day1 vs. day2, day2 vs. day3, day7 vs. 1 month, 1-monthvs. 3-months and Hct values at 3-months vs. 6-months. A total of 21 patients received blood transfusion perioperatively, among whom 4 patients were at postoperative day3and 5 patients were at day4. Conclusion Hb and Hct concentrations dramatically decreased during the first few days following TKA surgery whilegradually recovered from postoperative day4 and approached to the preoperative values at 3-months postoperatively. The changing patterns indicated an optimal timing of blood determination on postoperative day3 or day4 to accurately reflect ongoing hidden blood loss for better guiding blood transfusions.


2021 ◽  
Vol 27 (2) ◽  
pp. 103-108
Author(s):  
Cemile Sevgi Polat ◽  
Didem Sezgin Özcan ◽  
Elif Umay Altaş ◽  
Şule Şahin Onat ◽  
Belma Füsun Köseoğlu

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